{"id":"https://openalex.org/W136126595","doi":null,"title":"[Spironolactone-induced pemphigoid].","display_name":"[Spironolactone-induced pemphigoid].","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W136126595","mag":"136126595","pmid":"https://pubmed.ncbi.nlm.nih.gov/9740867"},"language":"fr","primary_location":{"id":"pmid:9740867","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9740867","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales de dermatologie et de venereologie","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059800915","display_name":"Florent Grange","orcid":"https://orcid.org/0000-0003-3387-0283","observed_orcids":["https://orcid.org/0000-0003-3387-0283"]},"institutions":[{"id":"https://openalex.org/I4210092661","display_name":"Hopitaux Civils de Colmar","ror":"https://ror.org/00jtq6z81","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092661"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Grange","raw_affiliation_strings":["Service de Dermatologie, H\u00f4pitaux civils de Colmar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Dermatologie, H\u00f4pitaux civils de Colmar","institution_ids":["https://openalex.org/I4210092661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001390105","display_name":"Yannis Scrivener","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Scrivener","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"A Koessler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Koessler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110635557","display_name":"Pierre Straub","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Straub","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110049709","display_name":"Jean Claude Guillaume","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J C Guillaume","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"124","issue":"10","first_page":"700","last_page":"2"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11730","display_name":"Autoimmune Bullous Skin Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11730","display_name":"Autoimmune Bullous Skin Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spironolactone","display_name":"spironolactone","score":0.9480000138282776},{"id":"https://openalex.org/keywords/drug-induced-pemphigoid","display_name":"drug-induced pemphigoid","score":0.8700000047683716},{"id":"https://openalex.org/keywords/bullous-pemphigoid","display_name":"bullous pemphigoid","score":0.9610000252723694},{"id":"https://openalex.org/keywords/drug-induced-skin-disease","display_name":"drug-induced skin disease","score":0.47600001096725464},{"id":"https://openalex.org/keywords/furosemide","display_name":"furosemide","score":0.675000011920929},{"id":"https://openalex.org/keywords/alimemazine","display_name":"alimemazine","score":0.6710000038146973},{"id":"https://openalex.org/keywords/flunarizine","display_name":"flunarizine","score":0.9409999847412109},{"id":"https://openalex.org/keywords/drug-withdrawal","display_name":"drug withdrawal","score":0.38100001215934753}],"concepts":[{"id":"https://openalex.org/C2776379505","wikidata":"https://www.wikidata.org/wiki/Q422188","display_name":"Spironolactone","level":3,"score":0.9626833200454712},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8452416658401489},{"id":"https://openalex.org/C2779252107","wikidata":"https://www.wikidata.org/wiki/Q1004647","display_name":"Bullous pemphigoid","level":3,"score":0.8217390775680542},{"id":"https://openalex.org/C2778075117","wikidata":"https://www.wikidata.org/wiki/Q881811","display_name":"Pemphigoid","level":4,"score":0.7214523553848267},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.6401829719543457},{"id":"https://openalex.org/C2777955127","wikidata":"https://www.wikidata.org/wiki/Q388801","display_name":"Furosemide","level":2,"score":0.4446829855442047},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3729337453842163},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1678837537765503},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.13496416807174683},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.10376405715942383}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004232","descriptor_name":"Diuretics","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010391","descriptor_name":"Pemphigoid, Bullous","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D010391","descriptor_name":"Pemphigoid, Bullous","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013148","descriptor_name":"Spironolactone","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D013848","descriptor_name":"Thigh","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9740867","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9740867","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales de dermatologie et de venereologie","raw_type":"Case Reports"},{"id":"mag:136126595","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9740867","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2285329188","https://openalex.org/W37140615","https://openalex.org/W2037156712","https://openalex.org/W3159934995","https://openalex.org/W2416966423","https://openalex.org/W2145800719","https://openalex.org/W4244723271","https://openalex.org/W1973477680","https://openalex.org/W2416975276","https://openalex.org/W3141807844"],"abstract_inverted_index":{"BACKGROUND:":[0],"Sporadic":[1],"observations":[2,131],"would":[3],"suggest":[4],"that":[5],"certain":[6],"drugs":[7],"play":[8],"a":[9,40],"role":[10,33,138],"in":[11,112,141],"the":[12,31,44,62,74,103,125,136],"development":[13,45,142],"of":[14,34,46,50,66,110,115,139,143],"pemphigoid.":[15,67],"A":[16],"recent":[17],"case-control":[18],"study":[19],"on":[20,61],"long-term":[21,88],"drug":[22],"use":[23,49],"associated":[24],"with":[25,127],"pemphigoid":[26,47,116,144],"was":[27,92],"unable":[28],"to":[29],"confirm":[30],"suspected":[32],"these":[35],"drugs,":[36],"but":[37],"did":[38],"demonstrate":[39],"significant":[41],"association":[42],"between":[43],"and":[48,69,85,98],"spironolactone.":[51],"CASE":[52],"REPORT:":[53],"An":[54],"82-year-old":[55],"patient":[56,77],"had":[57,78],"bullous":[58],"erythematous":[59],"lesions":[60,96],"left":[63],"thigh":[64],"suggestive":[65],"Histology":[68],"direct":[70],"cutaneous":[71,95],"immunofluorescence":[72],"confirmed":[73],"diagnosis.":[75],"The":[76,94,107],"been":[79],"taking":[80],"alimemazine,":[81],"adrafinil,":[82],"flunarizine,":[83],"spironolactone":[84,111,140],"furosemide":[86],"as":[87],"treatment.":[89],"Spironolactone":[90],"alone":[91],"withdrawn.":[93],"regressed":[97],"have":[99],"not":[100],"recurred":[101],"during":[102],"18-month":[104],"follow-up.":[105],"DISCUSSION:":[106],"causal":[108,137],"effect":[109],"this":[113],"case":[114],"is":[117,122],"quite":[118],"plausible.":[119],"This":[120],"hypothesis":[121],"favored":[123],"by":[124],"agreement":[126],"epidemiological":[128],"data.":[129],"Other":[130],"are":[132],"however":[133],"required":[134],"before":[135],"can":[145],"be":[146],"confirmed.":[147]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}