{"id":"https://openalex.org/W135886672","doi":"https://doi.org/10.1007/978-1-4615-3806-6_11","title":"Interactions between the Contact System, Neutrophils and Fibrinogen","display_name":"Interactions between the Contact System, Neutrophils and Fibrinogen","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W135886672","doi":"https://doi.org/10.1007/978-1-4615-3806-6_11","mag":"135886672","pmid":"https://pubmed.ncbi.nlm.nih.gov/1966352"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4615-3806-6_11","doi":"https://doi.org/10.1007/978-1-4615-3806-6_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-3806-6_11","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W562518803","display_name":"Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104652394","display_name":"Robert W. Colman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert W. Colman","raw_affiliation_strings":["Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140","Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA, 19140, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140","institution_ids":["https://openalex.org/I84392919"]},{"raw_affiliation_string":"Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA, 19140, USA","institution_ids":["https://openalex.org/I84392919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5104652394"],"corresponding_institution_ids":["https://openalex.org/I84392919"],"apc_list":null,"apc_paid":null,"fwci":0.6696,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.71052632,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"281","issue":null,"first_page":"105","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contact-system","display_name":"contact system","score":0.7319999933242798},{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.7480000257492065},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.8759999871253967},{"id":"https://openalex.org/keywords/high-molecular-weight-kininogen","display_name":"high molecular weight kininogen","score":0.9819999933242798},{"id":"https://openalex.org/keywords/kallikrein","display_name":"kallikrein","score":0.8650000095367432},{"id":"https://openalex.org/keywords/integrins","display_name":"integrins","score":0.6859999895095825},{"id":"https://openalex.org/keywords/fibrinogen-gamma-chain","display_name":"fibrinogen gamma chain","score":0.6349999904632568},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.5130000114440918},{"id":"https://openalex.org/keywords/glycoprotein-iib-iiia","display_name":"integrin \u03b1IIb\u03b23","score":0.7829999923706055}],"concepts":[{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.7497671842575073},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3784281611442566},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3594967722892761},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3141939640045166},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1668078899383545}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002449","descriptor_name":"Cell Aggregation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007704","descriptor_name":"Kininogens","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017981","descriptor_name":"Receptors, Neurotransmitter","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018000","descriptor_name":"Receptors, Peptide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4615-3806-6_11","doi":"https://doi.org/10.1007/978-1-4615-3806-6_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-3806-6_11","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},{"id":"pmid:1966352","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1966352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in experimental medicine and biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1633218185","display_name":null,"funder_award_id":"HL 19055","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1731336883","display_name":"PHYSIOLOGY OF BLOOD DURING EXTRACORPOREAL BYPASS","funder_award_id":"5r01hl019055-21","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1839165806","display_name":null,"funder_award_id":"HL 24365","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5273409778","display_name":"BIOCHEMISTRY AND PATHOPHYSIOLOGY OF PLASMA KALLIKREIN","funder_award_id":"5r01hl024365-11","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1423223045","https://openalex.org/W1488543398","https://openalex.org/W1513000136","https://openalex.org/W1534869523","https://openalex.org/W1536465820","https://openalex.org/W1545341742","https://openalex.org/W1569353770","https://openalex.org/W1582888773","https://openalex.org/W1588127588","https://openalex.org/W1599568592","https://openalex.org/W1969632860","https://openalex.org/W1976257261","https://openalex.org/W1977580980","https://openalex.org/W1985334666","https://openalex.org/W1986866278","https://openalex.org/W1987568997","https://openalex.org/W1993345959","https://openalex.org/W1994610964","https://openalex.org/W1998623051","https://openalex.org/W2004793126","https://openalex.org/W2012330153","https://openalex.org/W2013381560","https://openalex.org/W2025562266","https://openalex.org/W2036688878","https://openalex.org/W2043813981","https://openalex.org/W2053125166","https://openalex.org/W2059777229","https://openalex.org/W2069718808","https://openalex.org/W2077702220","https://openalex.org/W2080580789","https://openalex.org/W2086232516","https://openalex.org/W2092079486","https://openalex.org/W2092462079","https://openalex.org/W2096144517","https://openalex.org/W2117343102","https://openalex.org/W2117944649","https://openalex.org/W2136016201","https://openalex.org/W2143734437","https://openalex.org/W2144694645","https://openalex.org/W2169211697","https://openalex.org/W2170684533","https://openalex.org/W2188674398","https://openalex.org/W2286906990","https://openalex.org/W2398177205","https://openalex.org/W2409351365","https://openalex.org/W2411733269","https://openalex.org/W2427652915","https://openalex.org/W2465590130","https://openalex.org/W2772099086","https://openalex.org/W2889538120"],"related_works":["https://openalex.org/W1963952199","https://openalex.org/W2165609919","https://openalex.org/W55368941","https://openalex.org/W7096121576","https://openalex.org/W2888996942","https://openalex.org/W2408554416","https://openalex.org/W1541073910","https://openalex.org/W2077634879","https://openalex.org/W2145523399","https://openalex.org/W2046811036"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}