{"id":"https://openalex.org/W135677128","doi":null,"title":"Bromocriptine mesylate for lactation suppression: a risk for postpartum hypertension?","display_name":"Bromocriptine mesylate for lactation suppression: a risk for postpartum hypertension?","publication_year":1989,"publication_date":"1989-10-01","ids":{"openalex":"https://openalex.org/W135677128","mag":"135677128","pmid":"https://pubmed.ncbi.nlm.nih.gov/2797633"},"language":"en","primary_location":{"id":"pmid:2797633","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2797633","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018340055","display_name":"D L Watson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210130380","display_name":"Hutzel Women's Hospital","ror":"https://ror.org/02paek818","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800326109","https://openalex.org/I4210130380"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D L Watson","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Wayne State University/Hutzel Hospital, Detroit, Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Wayne State University/Hutzel Hospital, Detroit, Michigan","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210130380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041626838","display_name":"Rajneet Bhatia","orcid":"https://orcid.org/0000-0002-9867-9618","observed_orcids":["https://orcid.org/0000-0002-9867-9618"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R K Bhatia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077345913","display_name":"Gwendolyn Norman","orcid":"https://orcid.org/0000-0003-0483-286X","observed_orcids":["https://orcid.org/0000-0003-0483-286X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G S Norman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012292755","display_name":"B A Brindley","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B A Brindley","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109760987","display_name":"Robert J. Sokol","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R J Sokol","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.3863,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.85179219,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"74","issue":"4","first_page":"573","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bromocriptine-mesylate","display_name":"bromocriptine mesylate","score":0.9909999966621399},{"id":"https://openalex.org/keywords/lactation-suppression","display_name":"lactation suppression","score":0.9129999876022339},{"id":"https://openalex.org/keywords/postpartum-hypertension","display_name":"postpartum hypertension","score":0.984000027179718},{"id":"https://openalex.org/keywords/postpartum-eclampsia","display_name":"postpartum eclampsia","score":0.8809999823570251},{"id":"https://openalex.org/keywords/gestational-hypertension","display_name":"gestational hypertension","score":0.9629999995231628},{"id":"https://openalex.org/keywords/idiosyncratic-adverse-drug-reactions","display_name":"idiosyncratic drug reactions","score":0.8029999732971191},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.8230000138282776},{"id":"https://openalex.org/keywords/chronic-hypertension","display_name":"chronic hypertension","score":0.800000011920929},{"id":"https://openalex.org/keywords/medication-safety-in-pregnancy","display_name":"drug safety in pregnancy","score":0.44600000977516174}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9499239921569824},{"id":"https://openalex.org/C2776856834","wikidata":"https://www.wikidata.org/wiki/Q413581","display_name":"Bromocriptine","level":4,"score":0.8858403563499451},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6586015224456787},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.64799964427948},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.548034131526947},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4319356381893158},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.417402058839798},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3584596514701843},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.34126514196395874},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.13465887308120728},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.12434577941894531},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001971","descriptor_name":"Bromocriptine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011644","descriptor_name":"Puerperal Disorders","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2797633","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2797633","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Journal Article"},{"id":"mag:135677128","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2797633","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2085655324","https://openalex.org/W2009585963","https://openalex.org/W95281427","https://openalex.org/W2017378099","https://openalex.org/W2918305652","https://openalex.org/W4302444459","https://openalex.org/W4238395674","https://openalex.org/W138019907","https://openalex.org/W4403931703","https://openalex.org/W2176333121"],"abstract_inverted_index":{"The":[0,25],"etiology":[1],"of":[2,22,27,71,77,85,92,128,195],"postpartum":[3,44,139,189],"eclampsia":[4],"and":[5,115,133],"hypertension":[6,140,163,177,202],"remains":[7],"controversial.":[8],"Recent":[9],"reports":[10],"have":[11],"suggested":[12],"a":[13,40,205],"possible":[14],"idiosyncratic":[15],"hypertensive":[16],"reaction":[17],"associated":[18],"with":[19,174,200],"the":[20,69,93,98,104,121,155,159,170,192],"use":[21,194],"bromocriptine":[23,101,160,180],"mesylate.":[24],"purpose":[26],"this":[28,72,196],"study":[29,73],"was":[30,97,103,165],"to":[31,138,209],"determine":[32],"whether":[33],"bromocriptine,":[34],"used":[35],"for":[36,43,68,181,188],"lactation":[37,182],"suppression,":[38],"is":[39],"risk":[41,187],"factor":[42],"hypertension.":[45,190],"In":[46],"1813":[47],"consecutively":[48],"delivered":[49],"staff":[50],"patients,":[51],"blood":[52],"pressures":[53],"at":[54,185],"three":[55,94],"separate":[56],"home":[57,95],"visits":[58],"were":[59],"obtained":[60],"between":[61],"3-21":[62],"days":[63],"postpartum.":[64],"Postpartum":[65],"hypertension,":[66,112,114,130,132],"defined":[67],"purposes":[70],"as":[74],"systolic":[75],"pressure":[76,84],"140":[78],"mmHg":[79,87],"or":[80,88],"greater":[81,89],"and/or":[82],"diastolic":[83],"90":[86],"on":[90],"any":[91],"visits,":[96],"dependent":[99],"variable;":[100],"exposure":[102],"independent":[105],"variable.":[106],"Covariates":[107],"included":[108],"age,":[109],"race,":[110,126],"chronic":[111,129],"pregnancy-induced":[113,131,162,176,201],"antihypertensive":[116,134],"medication.":[117],"Discriminant":[118],"analysis,":[119],"including":[120],"first-order":[122],"interactions,":[123],"revealed":[124],"that":[125,172],"history":[127],"medication":[135],"contributed":[136],"significantly":[137],"(F":[141],"(7,":[142],"1803)":[143],"=":[144],"107.9;":[145],"P":[146],"less":[147],"than":[148],".001,":[149],"explained":[150],"variance":[151],"30%).":[152],"Of":[153],"all":[154],"interaction":[156,164],"terms,":[157],"only":[158],"by":[161],"significant.":[166],"These":[167],"findings":[168],"support":[169],"contention":[171],"patients":[173,199],"antepartum":[175],"who":[178],"receive":[179],"suppression":[183],"are":[184],"increased":[186],"Avoiding":[191],"elective":[193],"drug":[197],"in":[198],"might":[203],"constitute":[204],"reasonable":[206],"clinical":[207],"response":[208],"these":[210],"findings.":[211]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}