{"id":"https://openalex.org/W134948765","doi":null,"title":"Bisphosphonates in the prevention and treatment of glucocorticoid-induced osteoporosis.","display_name":"Bisphosphonates in the prevention and treatment of glucocorticoid-induced osteoporosis.","publication_year":2000,"publication_date":"2000-09-01","ids":{"openalex":"https://openalex.org/W134948765","mag":"134948765","pmid":"https://pubmed.ncbi.nlm.nih.gov/11032210"},"language":"en","primary_location":{"id":"pmid:11032210","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11032210","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of family practice","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029508997","display_name":"M M Blair","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M M Blair","raw_affiliation_strings":["Medical University of South Carolina, Charleston, USA. blairmm@musc.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical University of South Carolina, Charleston, USA. blairmm@musc.edu","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108561504","display_name":"Deborah Stier Carson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D S Carson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"R Barrington","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Barrington","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.253,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.79745738,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"49","issue":"9","first_page":"839","last_page":"48"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bisphosphonates","display_name":"bisphosphonates","score":1.0},{"id":"https://openalex.org/keywords/glucocorticoid-induced-osteoporosis","display_name":"glucocorticoid-induced osteoporosis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/corticosteroid-induced-bone-loss","display_name":"corticosteroid-induced bone loss","score":0.9049999713897705},{"id":"https://openalex.org/keywords/osteoporosis-prevention","display_name":"osteoporosis prevention","score":0.9129999876022339},{"id":"https://openalex.org/keywords/osteoporosis-treatment","display_name":"osteoporosis treatment","score":0.9100000262260437},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.9980000257492065},{"id":"https://openalex.org/keywords/fracture-risk-reduction","display_name":"fracture risk reduction","score":0.8960000276565552},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.953000009059906},{"id":"https://openalex.org/keywords/premenopausal-women","display_name":"premenopausal women","score":0.9210000038146973},{"id":"https://openalex.org/keywords/drug-safety-and-tolerability","display_name":"drug safety and tolerability","score":0.875}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9564218521118164},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.8001546859741211},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5262150764465332},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.5204418301582336},{"id":"https://openalex.org/C136524200","wikidata":"https://www.wikidata.org/wiki/Q3136977","display_name":"Jadad scale","level":4,"score":0.4323718547821045},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.43043631315231323},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.41660749912261963},{"id":"https://openalex.org/C2777251235","wikidata":"https://www.wikidata.org/wiki/Q412205","display_name":"Bisphosphonate","level":3,"score":0.4140973389148712},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.41399645805358887},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39974987506866455},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3463081121444702},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33465105295181274},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.2663878798484802},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004164","descriptor_name":"Diphosphonates","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004164","descriptor_name":"Diphosphonates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004164","descriptor_name":"Diphosphonates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005938","descriptor_name":"Glucocorticoids","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019317","descriptor_name":"Evidence-Based Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:11032210","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11032210","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of family practice","raw_type":"Journal Article"},{"id":"mag:134948765","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11032210","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7099999785423279,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2021034959","https://openalex.org/W2472805311","https://openalex.org/W4250477855","https://openalex.org/W2155941341","https://openalex.org/W7097103085","https://openalex.org/W1990059084","https://openalex.org/W2321773152","https://openalex.org/W2026342986","https://openalex.org/W2044204587","https://openalex.org/W4248486577"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"summarize":[2],"the":[3,6,11,22,39,43,48,56,80,98,102,105,132,142,149,167,191,198,216],"literature":[4,33],"concerning":[5,21,42,111,139,190],"use":[7,24,44,81],"of":[8,15,25,45,52,65,82,101,151,188,193,202,221],"bisphosphonates":[9,46,84,152,241],"in":[10,38,47,85,117,141,157,175,210],"prevention":[12,49],"and":[13,18,60,68,123,242],"treatment":[14,51],"corticosteroid-induced":[16,53,160,180],"osteoporosis":[17,54],"make":[19],"recommendations":[20],"proper":[23],"these":[26,194],"agents.":[27,244],"SEARCH":[28],"STRATEGIES:":[29],"We":[30,74,96],"conducted":[31],"a":[32,186],"search":[34],"to":[35,153,165,196,223,228],"identify":[36],"studies":[37,226],"English":[40],"language":[41],"or":[50,219],"using":[55,104],"MEDLINE,":[57],"CURRENT":[58],"CONTENTS,":[59],"HEALTHSTAR":[61],"electronic":[62],"databases,":[63],"bibliographies":[64],"selected":[66],"citations,":[67],"recent":[69],"meeting":[70],"abstracts.":[71],"SELECTION":[72],"CRITERIA:":[73],"included":[75],"randomized":[76],"controlled":[77],"trials":[78,103,239],"evaluating":[79],"oral":[83],"adults":[86],"by":[87],"central":[88],"dual":[89],"X-ray":[90],"absorptiometry.":[91],"DATA":[92],"COLLECTION":[93],"AND":[94],"ANALYSIS:":[95],"assessed":[97],"methodologic":[99],"quality":[100],"Jadad":[106],"criteria.":[107],"Data":[108,135],"were":[109,136],"collected":[110],"bone":[112,181],"mineral":[113],"density":[114],"(BMD)":[115],"changes":[116,140],"multiple":[118],"areas,":[119],"fracture":[120,155,203,230],"rates,":[121],"safety,":[122],"tolerability.":[124],"MAIN":[125],"RESULTS:":[126],"Bisphosphonates":[127,171],"generally":[128],"increased":[129,173],"BMD":[130,174],"at":[131,177],"lumbar":[133],"spine.":[134],"less":[137],"clear":[138],"femoral":[143],"area.":[144],"Little":[145],"information":[146],"exists":[147],"about":[148],"ability":[150,192],"reduce":[154],"risk":[156,178,231],"patients":[158,176],"with":[159,240],"osteoporosis.":[161],"Postmenopausal":[162],"women":[163,209],"seemed":[164],"receive":[166],"most":[168],"benefit.":[169],"CONCLUSIONS:":[170],"significantly":[172],"for":[179],"loss.":[182],"However,":[183],"there":[184],"is":[185],"sparsity":[187],"data":[189],"agents":[195],"affect":[197],"clinically":[199],"important":[200],"outcome":[201],"rate":[204],"reduction,":[205],"especially":[206],"among":[207],"premenopausal":[208],"whom":[211],"fractures":[212],"are":[213,233],"rare":[214],"within":[215],"first":[217],"year":[218],"2":[220],"exposure":[222],"corticosteroids.":[224],"Long-term":[225],"powered":[227],"detect":[229],"reduction":[232],"needed":[234],"as":[235,237],"well":[236],"comparative":[238],"other":[243]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}