{"id":"https://openalex.org/W13429889","doi":"https://doi.org/10.1023/a:1006509312674","title":"Relation of matrilysin messenger RNA expression with invasive activity in human gastric cancer","display_name":"Relation of matrilysin messenger RNA expression with invasive activity in human gastric cancer","publication_year":1998,"publication_date":"1998-05-01","ids":{"openalex":"https://openalex.org/W13429889","doi":"https://doi.org/10.1023/a:1006509312674","mag":"13429889","pmid":"https://pubmed.ncbi.nlm.nih.gov/9626810"},"language":"en","primary_location":{"id":"doi:10.1023/a:1006509312674","doi":"https://doi.org/10.1023/a:1006509312674","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1006509312674","pdf_url":null,"source":{"id":"https://openalex.org/S100674681","display_name":"Clinical & Experimental Metastasis","issn_l":"0262-0898","issn":["0262-0898","1573-7276"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & Experimental Metastasis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089257590","display_name":"Akinori Senota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akinori Senota","raw_affiliation_strings":["First Department of Internal Medicine, Sapporo Medical University, Japan","First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Sapporo Medical University, Japan","institution_ids":["https://openalex.org/I141882310"]},{"raw_affiliation_string":"First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan","institution_ids":["https://openalex.org/I141882310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109325065","display_name":"Fumio Itoh","orcid":"https://orcid.org/0000-0003-3411-0278","observed_orcids":["https://orcid.org/0000-0003-3411-0278"]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Fumio Itoh","raw_affiliation_strings":["First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan","institution_ids":["https://openalex.org/I141882310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014493260","display_name":"Hiroyuki Yamamoto","orcid":"https://orcid.org/0000-0003-4742-7653","observed_orcids":["https://orcid.org/0000-0003-4742-7653"]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Yamamoto","raw_affiliation_strings":["First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan","institution_ids":["https://openalex.org/I141882310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045458943","display_name":"Yasushi Adachi","orcid":"https://orcid.org/0000-0002-2530-1745","observed_orcids":["https://orcid.org/0000-0002-2530-1745"]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Adachi","raw_affiliation_strings":["First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan","institution_ids":["https://openalex.org/I141882310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004215583","display_name":"Yuji Hinoda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuji Hinoda","raw_affiliation_strings":["First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan","institution_ids":["https://openalex.org/I141882310"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111631917","display_name":"Kohzoh Imai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141882310","display_name":"Sapporo Medical University","ror":"https://ror.org/01h7cca57","country_code":"JP","type":"education","lineage":["https://openalex.org/I141882310"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kohzoh Imai","raw_affiliation_strings":["First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Internal Medicine, Sapporo Medical University, Chuo-ku, Sapporo, Japan","institution_ids":["https://openalex.org/I141882310"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I141882310"],"apc_list":{"value":5090,"currency":"USD","value_usd":5090},"apc_paid":null,"fwci":1.5014,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.81174312,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"16","issue":"4","first_page":"313","last_page":"321"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13437","display_name":"Mechanisms of cancer metastasis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/matrilysin","display_name":"matrilysin","score":1.0},{"id":"https://openalex.org/keywords/matrix-metalloproteinases","display_name":"matrix metalloproteinases","score":0.8960000276565552},{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.9779999852180481},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.9549999833106995},{"id":"https://openalex.org/keywords/mrna-expression","display_name":"mRNA expression","score":0.753000020980835},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6510000228881836},{"id":"https://openalex.org/keywords/subserosal-invasion","display_name":"subserosal invasion","score":0.6140000224113464},{"id":"https://openalex.org/keywords/dna-transfection","display_name":"DNA transfection","score":0.7419999837875366},{"id":"https://openalex.org/keywords/gastric-cancer-cell-lines","display_name":"gastric cancer cell lines","score":0.7120000123977661}],"concepts":[{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.8021907806396484},{"id":"https://openalex.org/C2779939298","wikidata":"https://www.wikidata.org/wiki/Q18029191","display_name":"Matrilysin","level":3,"score":0.6919904947280884},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.6837468147277832},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.605291485786438},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.5463774800300598},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4422447979450226},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42837655544281006},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4268915057182312},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41440466046333313},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37726348638534546},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3603147268295288},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33356788754463196},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23256176710128784},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.23191070556640625},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11560511589050293}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004792","descriptor_name":"Enzyme Precursors","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008666","descriptor_name":"Metalloendopeptidases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008666","descriptor_name":"Metalloendopeptidases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008666","descriptor_name":"Metalloendopeptidases","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020783","descriptor_name":"Matrix Metalloproteinase 7","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1023/a:1006509312674","doi":"https://doi.org/10.1023/a:1006509312674","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1006509312674","pdf_url":null,"source":{"id":"https://openalex.org/S100674681","display_name":"Clinical & Experimental Metastasis","issn_l":"0262-0898","issn":["0262-0898","1573-7276"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & Experimental Metastasis","raw_type":"journal-article"},{"id":"pmid:9626810","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9626810","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & experimental metastasis","raw_type":"Journal Article"},{"id":"mag:2336668533","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/500000159943","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W70137129","https://openalex.org/W746902434","https://openalex.org/W1493755221","https://openalex.org/W1500781084","https://openalex.org/W1515173040","https://openalex.org/W1604342691","https://openalex.org/W1641843888","https://openalex.org/W1676799983","https://openalex.org/W1954929088","https://openalex.org/W1969222740","https://openalex.org/W1974384889","https://openalex.org/W1982977732","https://openalex.org/W1985491088","https://openalex.org/W1993280782","https://openalex.org/W2007672389","https://openalex.org/W2011807008","https://openalex.org/W2015361704","https://openalex.org/W2026151657","https://openalex.org/W2038314223","https://openalex.org/W2068013043","https://openalex.org/W2082183799","https://openalex.org/W2104193952","https://openalex.org/W2109658199","https://openalex.org/W2116477272","https://openalex.org/W2116479391","https://openalex.org/W2123424871","https://openalex.org/W2134812217","https://openalex.org/W2138270253","https://openalex.org/W2141959092","https://openalex.org/W2142121571","https://openalex.org/W2145310996","https://openalex.org/W2158565740","https://openalex.org/W2161892290","https://openalex.org/W2335804637","https://openalex.org/W2415881300","https://openalex.org/W2419571328"],"related_works":["https://openalex.org/W2351451926","https://openalex.org/W2336668533","https://openalex.org/W2006686322","https://openalex.org/W2123757803","https://openalex.org/W2189143161","https://openalex.org/W247635409","https://openalex.org/W1989012228","https://openalex.org/W2360334021","https://openalex.org/W2348581722","https://openalex.org/W2093512107"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}