{"id":"https://openalex.org/W131022151","doi":null,"title":"A study of the role of monocyte functional subpopulations in patients with carotid atherosclerosis and coronary artery disease","display_name":"A study of the role of monocyte functional subpopulations in patients with carotid atherosclerosis and coronary artery disease","publication_year":2014,"publication_date":"2014-12-01","ids":{"openalex":"https://openalex.org/W131022151","mag":"131022151"},"language":"en","primary_location":{"id":"pmh:oai:etheses.bham.ac.uk:5549","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","pdf_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004440466","display_name":"Anthony S. Jaipersad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Anthony Jaipersad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5004440466"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/monocyte-subsets","display_name":"monocyte subsets","score":0.9259999990463257},{"id":"https://openalex.org/keywords/carotid-atherosclerosis","display_name":"carotid atherosclerosis","score":0.9549999833106995},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/contrast-enhanced-ultrasound","display_name":"contrast-enhanced ultrasound","score":0.7940000295639038},{"id":"https://openalex.org/keywords/neovascularization","display_name":"neovascularization","score":0.8700000047683716},{"id":"https://openalex.org/keywords/ccr2","display_name":"CCR2","score":0.8610000014305115},{"id":"https://openalex.org/keywords/cd14","display_name":"CD14","score":0.8669999837875366},{"id":"https://openalex.org/keywords/cd16","display_name":"CD16","score":0.9869999885559082},{"id":"https://openalex.org/keywords/carotid-intima-media-thickness","display_name":"carotid intima-media thickness","score":0.8949999809265137},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9169999957084656},{"id":"https://openalex.org/keywords/statin-therapy","display_name":"statin therapy","score":0.9350000023841858},{"id":"https://openalex.org/keywords/atherosclerosis-severity","display_name":"atherosclerosis severity","score":0.6439999938011169}],"concepts":[{"id":"https://openalex.org/C206615009","wikidata":"https://www.wikidata.org/wiki/Q4035572","display_name":"CCR2","level":5,"score":0.8243480324745178},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.7781258821487427},{"id":"https://openalex.org/C2778513237","wikidata":"https://www.wikidata.org/wiki/Q419553","display_name":"CD14","level":3,"score":0.7669111490249634},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7217642664909363},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.6892112493515015},{"id":"https://openalex.org/C2781462264","wikidata":"https://www.wikidata.org/wiki/Q78482053","display_name":"CD16","level":5,"score":0.5635489821434021},{"id":"https://openalex.org/C2776184368","wikidata":"https://www.wikidata.org/wiki/Q1576205","display_name":"Carotid artery disease","level":4,"score":0.5467681884765625},{"id":"https://openalex.org/C2779339615","wikidata":"https://www.wikidata.org/wiki/Q2698596","display_name":"Intima-media thickness","level":3,"score":0.49778246879577637},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4793306589126587},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43843764066696167},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4270259141921997},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.4138137102127075},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.39193129539489746},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.36128950119018555},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3583090007305145},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35344457626342773},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.340704083442688},{"id":"https://openalex.org/C2987047532","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Carotid arteries","level":2,"score":0.20447295904159546},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.15094393491744995},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11851492524147034},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.11740481853485107},{"id":"https://openalex.org/C12823836","wikidata":"https://www.wikidata.org/wiki/Q24720618","display_name":"Chemokine receptor","level":4,"score":0.08594077825546265},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.0},{"id":"https://openalex.org/C2781068581","wikidata":"https://www.wikidata.org/wiki/Q5045544","display_name":"Carotid endarterectomy","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:etheses.bham.ac.uk:5549","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","pdf_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:131022151","doi":null,"is_oa":false,"landing_page_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etheses.bham.ac.uk:5549","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","pdf_url":"http://etheses.bham.ac.uk/5549/5/Jaipersad14MD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W131022151.pdf","grobid_xml":"https://content.openalex.org/works/W131022151.grobid-xml"},"referenced_works_count":241,"referenced_works":["https://openalex.org/W5896399","https://openalex.org/W12613825","https://openalex.org/W21438853","https://openalex.org/W23687344","https://openalex.org/W32167704","https://openalex.org/W81986490","https://openalex.org/W94153032","https://openalex.org/W111332543","https://openalex.org/W172183759","https://openalex.org/W336237379","https://openalex.org/W589142326","https://openalex.org/W1410931458","https://openalex.org/W1493858061","https://openalex.org/W1495287184","https://openalex.org/W1506270602","https://openalex.org/W1507921386","https://openalex.org/W1507950132","https://openalex.org/W1561059299","https://openalex.org/W1564674105","https://openalex.org/W1592045168","https://openalex.org/W1594181759","https://openalex.org/W1597409170","https://openalex.org/W1599975943","https://openalex.org/W1600542667","https://openalex.org/W1603077759","https://openalex.org/W1605018996","https://openalex.org/W1640610491","https://openalex.org/W1650965741","https://openalex.org/W1679229092","https://openalex.org/W1783580437","https://openalex.org/W1852654097","https://openalex.org/W1852797979","https://openalex.org/W1905974666","https://openalex.org/W1923270121","https://openalex.org/W1949173079","https://openalex.org/W1950146087","https://openalex.org/W1964657490","https://openalex.org/W1964794100","https://openalex.org/W1966042804","https://openalex.org/W1966126044","https://openalex.org/W1969262255","https://openalex.org/W1970016838","https://openalex.org/W1970017835","https://openalex.org/W1972168139","https://openalex.org/W1973404873","https://openalex.org/W1974009038","https://openalex.org/W1975868692","https://openalex.org/W1977319681","https://openalex.org/W1978644984","https://openalex.org/W1980932859","https://openalex.org/W1984378291","https://openalex.org/W1985564012","https://openalex.org/W1986559037","https://openalex.org/W1990965637","https://openalex.org/W1991226754","https://openalex.org/W1991267259","https://openalex.org/W1994374799","https://openalex.org/W1994787312","https://openalex.org/W1995827857","https://openalex.org/W1995911944","https://openalex.org/W1996017815","https://openalex.org/W1996430165","https://openalex.org/W1997204455","https://openalex.org/W1998252372","https://openalex.org/W1998405343","https://openalex.org/W2000502243","https://openalex.org/W2001644716","https://openalex.org/W2002131026","https://openalex.org/W2003307830","https://openalex.org/W2007091795","https://openalex.org/W2007227806","https://openalex.org/W2008207915","https://openalex.org/W2008214565","https://openalex.org/W2010734847","https://openalex.org/W2010804206","https://openalex.org/W2013135918","https://openalex.org/W2015954946","https://openalex.org/W2017041417","https://openalex.org/W2017459928","https://openalex.org/W2017574292","https://openalex.org/W2017763556","https://openalex.org/W2018702616","https://openalex.org/W2020024962","https://openalex.org/W2024281966","https://openalex.org/W2024815256","https://openalex.org/W2025299174","https://openalex.org/W2026003575","https://openalex.org/W2026125174","https://openalex.org/W2027244023","https://openalex.org/W2029194789","https://openalex.org/W2029224544","https://openalex.org/W2030106461","https://openalex.org/W2030160629","https://openalex.org/W2031131334","https://openalex.org/W2031359035","https://openalex.org/W2034001161","https://openalex.org/W2034911894","https://openalex.org/W2036435465","https://openalex.org/W2037033559","https://openalex.org/W2037789405","https://openalex.org/W2038809846","https://openalex.org/W2039666458","https://openalex.org/W2042653767","https://openalex.org/W2042842188","https://openalex.org/W2044009235","https://openalex.org/W2044738371","https://openalex.org/W2044818322","https://openalex.org/W2045247659","https://openalex.org/W2045700517","https://openalex.org/W2048380290","https://openalex.org/W2049476825","https://openalex.org/W2049746081","https://openalex.org/W2049780044","https://openalex.org/W2050000945","https://openalex.org/W2057106552","https://openalex.org/W2057576736","https://openalex.org/W2057688025","https://openalex.org/W2059155403","https://openalex.org/W2060340186","https://openalex.org/W2061945278","https://openalex.org/W2063535670","https://openalex.org/W2065957571","https://openalex.org/W2066888615","https://openalex.org/W2067688851","https://openalex.org/W2068102230","https://openalex.org/W2069090934","https://openalex.org/W2069092801","https://openalex.org/W2069961866","https://openalex.org/W2070040521","https://openalex.org/W2072751592","https://openalex.org/W2072920954","https://openalex.org/W2073472691","https://openalex.org/W2073621056","https://openalex.org/W2074253462","https://openalex.org/W2074937504","https://openalex.org/W2075333521","https://openalex.org/W2076631681","https://openalex.org/W2076984312","https://openalex.org/W2077767552","https://openalex.org/W2078697224","https://openalex.org/W2079825774","https://openalex.org/W2080798849","https://openalex.org/W2083222165","https://openalex.org/W2083261882","https://openalex.org/W2084112421","https://openalex.org/W2085390558","https://openalex.org/W2086244971","https://openalex.org/W2088302753","https://openalex.org/W2090819042","https://openalex.org/W2092001446","https://openalex.org/W2092150075","https://openalex.org/W2092515735","https://openalex.org/W2092692976","https://openalex.org/W2094866977","https://openalex.org/W2095263277","https://openalex.org/W2095282566","https://openalex.org/W2098674532","https://openalex.org/W2099144412","https://openalex.org/W2099216922","https://openalex.org/W2099992963","https://openalex.org/W2100955335","https://openalex.org/W2101559592","https://openalex.org/W2101726084","https://openalex.org/W2101955404","https://openalex.org/W2103227975","https://openalex.org/W2104566530","https://openalex.org/W2106697674","https://openalex.org/W2107445027","https://openalex.org/W2110310553","https://openalex.org/W2112911107","https://openalex.org/W2114279349","https://openalex.org/W2114495365","https://openalex.org/W2116563879","https://openalex.org/W2116756227","https://openalex.org/W2117307804","https://openalex.org/W2118154631","https://openalex.org/W2120582139","https://openalex.org/W2120621109","https://openalex.org/W2121165964","https://openalex.org/W2121338555","https://openalex.org/W2122251453","https://openalex.org/W2122975632","https://openalex.org/W2123193821","https://openalex.org/W2124109795","https://openalex.org/W2125689680","https://openalex.org/W2126587403","https://openalex.org/W2129716877","https://openalex.org/W2130019417","https://openalex.org/W2131434404","https://openalex.org/W2132107001","https://openalex.org/W2133368506","https://openalex.org/W2133665922","https://openalex.org/W2133858220","https://openalex.org/W2134575914","https://openalex.org/W2135304449","https://openalex.org/W2135647797","https://openalex.org/W2136480005","https://openalex.org/W2136973280","https://openalex.org/W2137374083","https://openalex.org/W2137441445","https://openalex.org/W2137596113","https://openalex.org/W2140252716","https://openalex.org/W2143835519","https://openalex.org/W2144976857","https://openalex.org/W2146672236","https://openalex.org/W2148017951","https://openalex.org/W2148749733","https://openalex.org/W2149973964","https://openalex.org/W2152063570","https://openalex.org/W2153608588","https://openalex.org/W2154177618","https://openalex.org/W2154514319","https://openalex.org/W2154676325","https://openalex.org/W2155410080","https://openalex.org/W2155761636","https://openalex.org/W2155877309","https://openalex.org/W2156013098","https://openalex.org/W2158318180","https://openalex.org/W2159193498","https://openalex.org/W2159767534","https://openalex.org/W2163049467","https://openalex.org/W2163127813","https://openalex.org/W2163301034","https://openalex.org/W2164777277","https://openalex.org/W2165834854","https://openalex.org/W2165909152","https://openalex.org/W2166603442","https://openalex.org/W2168833608","https://openalex.org/W2171650049","https://openalex.org/W2171998177","https://openalex.org/W2184486465","https://openalex.org/W2201971948","https://openalex.org/W2316997036","https://openalex.org/W2324841714","https://openalex.org/W2334205878","https://openalex.org/W2335455113","https://openalex.org/W2402832492","https://openalex.org/W2408344606","https://openalex.org/W2422607663","https://openalex.org/W2510284052","https://openalex.org/W2615751376"],"related_works":["https://openalex.org/W2038809846","https://openalex.org/W2904145782","https://openalex.org/W7213862055","https://openalex.org/W2966634881","https://openalex.org/W4234038972","https://openalex.org/W2067208148","https://openalex.org/W4403771136","https://openalex.org/W2268899648","https://openalex.org/W2323984416","https://openalex.org/W2305363321"],"abstract_inverted_index":{"This":[0,177],"thesis":[1,178],"focuses":[2],"on":[3,175],"monocyte":[4,50,64,148,164],"subsets":[5,65],"and":[6,34,46,70,109,193],"furthers":[7],"the":[8,14,42,141,185],"understanding":[9,183],"of":[10,21,44,77,107,124,143,154,184,188],"their":[11],"relationships":[12],"to":[13,40,111,130,180],"atherosclerotic":[15,191],"disease":[16,32,38,192],"process.":[17],"A":[18],"novel":[19],"method":[20],"carotid":[22,31,118],"contrast":[23],"ultrasound":[24],"(CEUS)":[25],"is":[26],"used":[27],"in":[28,114,133,140,171,190],"those":[29,115,134],"with":[30,49,75,89,94,105,116,135],"(CD)":[33],"pre-existing":[35,90,95],"coronary":[36],"artery":[37],"(CAD)":[39],"detect":[41],"presence":[43,142],"neovascularisation":[45],"correlates":[47],"this":[48,160],"subset":[51,165],"totals":[52],"determined":[53],"by":[54,79],"flow":[55],"cytometry/":[56],"enzyme-":[57],"linked":[58],"immunosorbent":[59],"assay":[60],"(ELISA).":[61],"\\n":[62,146,202],"\\nThree":[63],"((CD14++CD16-CCR2+":[66],"(Mon1),":[67],"CD14++CD16+CCR2+":[68],"(Mon2)":[69],"CD14+CD16++CCR2-":[71],"(Mon3)),":[72],"are":[73],"compared":[74],"severity":[76,106],"CD":[78,137],"division":[80],"into":[81],"4":[82],"groups":[83],"(each":[84],"40":[85],"patients);":[86],"grp.1=":[87],"CD>50%":[88],"CAD,":[91,96],"grp.2=":[92],"CD<50%":[93],"grp.3=hypercholesterolemia":[97],"(HC),":[98],"grp.4=":[99],"normocholesterolaemic":[100],"(NC).":[101],"Monllevels":[102],"were":[103],"increased":[104,117,132],"CD,":[108],"found":[110],"be":[112,131],"predictive":[113],"intima":[119],"media":[120],"thickness,":[121],"a":[122,169,197],"marker":[123],"systemic":[125],"atherosclerosis.":[126],"Mon3,":[127],"was":[128],"shown":[129],"moderate":[136],"but":[138,167],"not":[139,162],"severe":[144],"disease.":[145],"\\nFinally,":[147],"levels":[149],"where":[150],"checked":[151],"after":[152],"cessation":[153],"statin":[155],"therapy":[156],"for":[157],"two":[158],"weeks,":[159],"did":[161],"affect":[163],"counts":[166],"caused":[168],"reduction":[170],"inflammatory":[172],"receptor":[173],"expression":[174],"Monl.":[176],"attempts":[179],"expand":[181],"one's":[182],"behavioral":[186],"heterogeneity":[187],"monocytes":[189],"demonstrates":[194],"CEUS":[195],"as":[196],"feasible":[198],"research":[199],"imaging":[200],"method.":[201]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}