{"id":"https://openalex.org/W13028128","doi":null,"title":"[Erythrocyte abnormalities in thyroid dysfunction].","display_name":"[Erythrocyte abnormalities in thyroid dysfunction].","publication_year":2010,"publication_date":"2010-11-01","ids":{"openalex":"https://openalex.org/W13028128","mag":"13028128","pmid":"https://pubmed.ncbi.nlm.nih.gov/21049405"},"language":"fr","primary_location":{"id":"pmid:21049405","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21049405","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"La Tunisie medicale","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109202859","display_name":"Souheil Omar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098525","display_name":"H\u00f4pital La Rabta","ror":"https://ror.org/00gffbx54","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210098525"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Souheil Omar","raw_affiliation_strings":["Laboratoire de Biochimie, Service d'Endocrinologie Diab\u00e9tologie, H\u00f4pital la Rabta, Tunis, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biochimie, Service d'Endocrinologie Diab\u00e9tologie, H\u00f4pital la Rabta, Tunis, Tunisia","institution_ids":["https://openalex.org/I4210098525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002200241","display_name":"Sameh Hadj Taeib","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sameh Hadj Taeib","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062076758","display_name":"Faouzi Kanoun","orcid":"https://orcid.org/0000-0003-2957-4377","observed_orcids":["https://orcid.org/0000-0003-2957-4377"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Faouzi Kanoun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090168662","display_name":"Bassem Hammami","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohamed Bassem Hammami","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003743830","display_name":"Samia Kamoun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samia Kamoun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071050143","display_name":"Ne\u00efla Ben Romdhane","orcid":"https://orcid.org/0000-0002-2068-824X","observed_orcids":["https://orcid.org/0000-0002-2068-824X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neila Ben Romdhane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007599948","display_name":"Moncef Feki","orcid":"https://orcid.org/0000-0003-1585-4052","observed_orcids":["https://orcid.org/0000-0003-1585-4052","https://orcid.org/0000-0001-7537-6297"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Moncef Feki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108615455","display_name":"H\u00e9dia Slimane","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hedia Slimane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5066153934","display_name":"Naziha Kaabachi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Naziha Kaabachi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9708,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.75688194,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"88","issue":"11","first_page":"783","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13374","display_name":"Hematological disorders and diagnostics","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythrocyte-abnormalities","display_name":"erythrocyte abnormalities","score":0.9909999966621399},{"id":"https://openalex.org/keywords/thyroid-disease","display_name":"thyroid dysfunction","score":0.9710000157356262},{"id":"https://openalex.org/keywords/hyperthyroidism","display_name":"hyperthyroidism","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":1.0},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.9100000262260437},{"id":"https://openalex.org/keywords/microcytosis","display_name":"microcytosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/macrocytosis","display_name":"macrocytosis","score":0.972000002861023},{"id":"https://openalex.org/keywords/normocytic-anemia","display_name":"normocytic anemia","score":0.9240000247955322},{"id":"https://openalex.org/keywords/mean-corpuscular-volume","display_name":"mean corpuscular volume","score":0.890999972820282},{"id":"https://openalex.org/keywords/mean-corpuscular-hemoglobin","display_name":"mean corpuscular hemoglobin","score":0.843999981880188},{"id":"https://openalex.org/keywords/free-thyroxine","display_name":"free thyroxine","score":0.859000027179718},{"id":"https://openalex.org/keywords/subclinical-thyroid-dysfunction","display_name":"subclinical thyroid dysfunction","score":0.8960000276565552}],"concepts":[{"id":"https://openalex.org/C2781400336","wikidata":"https://www.wikidata.org/wiki/Q1091552","display_name":"Microcytosis","level":4,"score":0.9099056124687195},{"id":"https://openalex.org/C2777195454","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Euthyroid","level":3,"score":0.8812693953514099},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8684345483779907},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6466203927993774},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.6320841312408447},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5956825017929077},{"id":"https://openalex.org/C2993291352","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid function","level":3,"score":0.587425708770752},{"id":"https://openalex.org/C2781291160","wikidata":"https://www.wikidata.org/wiki/Q1886493","display_name":"Macrocytosis","level":3,"score":0.5742257237434387},{"id":"https://openalex.org/C2780176905","wikidata":"https://www.wikidata.org/wiki/Q6673122","display_name":"Thyroid disease","level":3,"score":0.5436716079711914},{"id":"https://openalex.org/C2778840127","wikidata":"https://www.wikidata.org/wiki/Q712838","display_name":"Thyroid function tests","level":3,"score":0.5064548254013062},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.49151381850242615},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4773816466331482},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.4659290015697479},{"id":"https://openalex.org/C2781058662","wikidata":"https://www.wikidata.org/wiki/Q1358504","display_name":"Mean corpuscular volume","level":3,"score":0.4475369453430176},{"id":"https://openalex.org/C2775897519","wikidata":"https://www.wikidata.org/wiki/Q1273048","display_name":"Mean corpuscular hemoglobin concentration","level":4,"score":0.42042461037635803},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.41454213857650757},{"id":"https://openalex.org/C2777417653","wikidata":"https://www.wikidata.org/wiki/Q1313081","display_name":"Iron deficiency","level":3,"score":0.25557366013526917}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D004909","descriptor_name":"Erythrocyte Indices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004913","descriptor_name":"Erythrocytes, Abnormal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013959","descriptor_name":"Thyroid Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:21049405","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21049405","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"La Tunisie medicale","raw_type":"English Abstract"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4210809500","https://openalex.org/W4322098310","https://openalex.org/W2609602633","https://openalex.org/W7126375201","https://openalex.org/W1859581417","https://openalex.org/W3202235962","https://openalex.org/W4386402187","https://openalex.org/W139507590","https://openalex.org/W3216742453","https://openalex.org/W4367369484"],"abstract_inverted_index":{"BACKGROUND:":[0],"Erythrocyte":[1],"abnormalities":[2,32,191,213],"are":[3,11,197],"frequently":[4,198],"associated":[5,199],"with":[6,52,113,130,136,152,162,168,180,200],"thyroid":[7,34,42,54,225],"dysfunction.":[8],"However,":[9],"they":[10],"rarely":[12],"investigated":[13,216],"and":[14,28,36,67,81,97,132,175,177,182,208,217],"related":[15],"to":[16,24],"the":[17,26,169],"thyroid.":[18],"AIM:":[19],"This":[20,46],"study":[21,48],"was":[22,62,73,109,124,144,156,165],"aimed":[23],"determine":[25],"nature":[27],"frequency":[29],"of":[30,106,128,134,148,160,171,186],"erythrocyte":[31,190,201],"in":[33,79,84,111,126,146,158,206,210],"disease":[35],"look":[37],"for":[38,64,69,117],"their":[39],"evolution":[40],"after":[41],"function":[43],"restoration.":[44],"METHODS:":[45],"retrospective":[47],"included":[49],"412":[50],"patients":[51,112,129,135,161],"peripheral":[53],"disease;":[55],"hyperthyroidism":[56,131],"(n=235)":[57],"or":[58,141,153],"hypothyroidism":[59,68,207],"(n=177).":[60],"Hyperthyroidism":[61],"considered":[63,110],"TSH<0.10":[65],"\u00ccUI/ml":[66],"TSH>5.0":[70],"\u00ccUI/ml.":[71],"Anemia":[72],"defined":[74],"by":[75,87,94,99],"hemoglobin":[76,102],"level<13":[77],"g/dl":[78,83],"men":[80],"<12":[82],"women,":[85],"microcytosis":[86,209],"mean":[88,100],"corpuscular":[89,101],"volume":[90],"(MCV)<80":[91],"fl,":[92,96],"macrocytosis":[93],"MCV>98":[95],"hypochromia":[98],"(MCH)<25":[103],"pg.":[104],"Restoration":[105],"euthyroid":[107,187],"state":[108],"normal":[114],"TSH":[115],"levels":[116],"at":[118],"least":[119],"3":[120],"months.":[121],"RESULTS:":[122],"Anaemia":[123],"observed":[125],"40.9%":[127],"57.1%":[133],"hypothyroidism.":[137],"Among":[138],"these,":[139],"normocytic":[140,204],"macrocytic":[142],"anaemia":[143,205],"present":[145],"46.3%":[147],"cases.":[149],"Whereas,":[150],"microcytosis,":[151],"without":[154],"anaemia,":[155],"noted":[157],"87.7%":[159],"hyperthyroidism.":[163,211],"FT4":[164],"positively":[166],"correlated":[167,179],"number":[170],"red":[172],"blood":[173],"cells":[174],"haemoglobin,":[176],"inversely":[178],"MCV":[181],"MCH.":[183],"After":[184],"restoration":[185],"state,":[188],"most":[189],"were":[192],"corrected.":[193,218],"CONCLUSION:":[194],"Thyroid":[195],"diseases":[196],"abnormalities,":[202],"including":[203],"These":[212],"should":[214],"be":[215],"Their":[219],"presence":[220],"could":[221],"steer":[222],"towards":[223],"subclinical":[224],"dysfunction,":[226],"allowing":[227],"its":[228],"early":[229],"management.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}