{"id":"https://openalex.org/W129490998","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_1081-c","title":"Abstract 1189: Changes in the Prevalence of Abnormal Lipid Fractions among US Adults: Results from the National Health and Nutrition Examination Survey II, III, and 1999\u20132006","display_name":"Abstract 1189: Changes in the Prevalence of Abnormal Lipid Fractions among US Adults: Results from the National Health and Nutrition Examination Survey II, III, and 1999\u20132006","publication_year":2008,"publication_date":"2008-10-28","ids":{"openalex":"https://openalex.org/W129490998","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_1081-c","mag":"129490998"},"language":"en","primary_location":{"id":"doi:10.1161/circ.118.suppl_18.s_1081-c","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_1081-c","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.118.suppl_18.s_1081-c","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103457846","display_name":"Jerome D. Cohen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405269232","display_name":"National Lipid Association","ror":"https://ror.org/03gh46007","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269232"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerome D Cohen","raw_affiliation_strings":["National Lipid Association, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Lipid Association, St Louis, MO","institution_ids":["https://openalex.org/I4405269232"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086835788","display_name":"Mark J. Cziraky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285906","display_name":"Carelon Research (United States)","ror":"https://ror.org/00n30fg43","country_code":"US","type":"company","lineage":["https://openalex.org/I4210115830","https://openalex.org/I4405285906"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark J Cziraky","raw_affiliation_strings":["HealthCore, Inc., Wilmington, DE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HealthCore, Inc., Wilmington, DE","institution_ids":["https://openalex.org/I4405285906"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084230583","display_name":"Terry A. Jacobson","orcid":"https://orcid.org/0000-0002-9926-2179","observed_orcids":["https://orcid.org/0000-0002-9926-2179"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terry A Jacobson","raw_affiliation_strings":["Emory Univ, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Univ, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102977350","display_name":"Anna E. Wallace","orcid":"https://orcid.org/0000-0003-2345-6636","observed_orcids":["https://orcid.org/0000-0003-2345-6636"]},"institutions":[{"id":"https://openalex.org/I4405285906","display_name":"Carelon Research (United States)","ror":"https://ror.org/00n30fg43","country_code":"US","type":"company","lineage":["https://openalex.org/I4210115830","https://openalex.org/I4405285906"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Wallace","raw_affiliation_strings":["HealthCore, Inc., Wilmington, DE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HealthCore, Inc., Wilmington, DE","institution_ids":["https://openalex.org/I4405285906"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056689039","display_name":"Cassie Cai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285906","display_name":"Carelon Research (United States)","ror":"https://ror.org/00n30fg43","country_code":"US","type":"company","lineage":["https://openalex.org/I4210115830","https://openalex.org/I4405285906"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cassie Cai","raw_affiliation_strings":["HealthCore, Inc., Wilmington, DE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HealthCore, Inc., Wilmington, DE","institution_ids":["https://openalex.org/I4405285906"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"118","issue":"suppl_18","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.5723000168800354,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.5723000168800354,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.396699994802475,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10010","display_name":"Obesity, Physical Activity, Diet","score":0.013399999588727951,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9779999852180481},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8180000185966492},{"id":"https://openalex.org/keywords/prevalence-trends","display_name":"prevalence trends","score":0.7760000228881836},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.8640000224113464},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9210000038146973},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9980000257492065},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.890999972820282},{"id":"https://openalex.org/keywords/nhanes","display_name":"NHANES","score":0.703000009059906},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.5640000104904175},{"id":"https://openalex.org/keywords/nhanes-ii","display_name":"NHANES II","score":0.4569999873638153},{"id":"https://openalex.org/keywords/nhanes-iii","display_name":"NHANES III","score":0.9900000095367432}],"concepts":[{"id":"https://openalex.org/C2779874844","wikidata":"https://www.wikidata.org/wiki/Q1967281","display_name":"National Health and Nutrition Examination Survey","level":3,"score":0.9669890403747559},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8915989398956299},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.887292742729187},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5579034090042114},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.530346691608429},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5222074389457703},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4983513355255127},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.29720115661621094},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.2066703736782074}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/circ.118.suppl_18.s_1081-c","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_1081-c","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.118.suppl_18.s_1081-c","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2159084635","https://openalex.org/W2101328789","https://openalex.org/W7206207722","https://openalex.org/W2911420357","https://openalex.org/W2168649151","https://openalex.org/W71342633","https://openalex.org/W2671932359","https://openalex.org/W2761775817","https://openalex.org/W196695463","https://openalex.org/W2118262141"],"abstract_inverted_index":{"Objective":[0],"To":[1],"examine":[2],"the":[3,20,35,42,130,172,186,193,219,231,300,314,319,323,335],"prevalence":[4,153,173,221,232],"of":[5,22,77,110,154,174,222,233,256,287,316],"abnormal":[6,81,111,155,175,187,234,288,301,347],"lipid":[7,37,82,112,348],"fractions":[8,113,349],"among":[9],"US":[10,115,324],"adults":[11,116,212],"from":[12,41,158,181,240],"1976":[13],"through":[14],"2006,":[15],"with":[16,120,213,258,265,275,342],"a":[17,311],"focus":[18,343],"on":[19,344],"relationship":[21],"dyslipidemia":[23,133,214,259,272,352],"and":[24,45,58,100,107,117,134,143,148,177,185,227,236,296,328,350],"obesity.":[25],"Methods":[26],"Adults":[27,264],"aged":[28],"20":[29],"to":[30,128,163,183,198,245,270],"74":[31],"years":[32],"who":[33],"took":[34],"blood":[36],"examination":[38],"were":[39,122,260,267],"selected":[40],"National":[43],"Health":[44],"Nutrition":[46],"Examination":[47],"Surveys":[48],"(NHANES):":[49],"NHANES":[50,54,59,141,161,166,225,228,243,248,294,297],"II":[51,162,226,244,295],"(1976":[52],"\u20131980),":[53],"III":[55],"(1988":[56],"\u20131994),":[57],"1999":[60,229,249],"\u20132006.":[61],"Obesity":[62],"was":[63,73,126,201,207,308],"defined":[64,74],"as":[65,75],"BMI":[66,257,276,317],"\u2265":[67,89,103],"30":[68],"kg/m":[69,279],"2":[70,280],".":[71],"Dyslipidemia":[72],"presence":[76],"one":[78],"or":[79],"more":[80,189,268,330],"fractions:":[83],"low":[84],"density":[85,93],"lipoprotein":[86,94],"cholesterol":[87,95],"(LDL-C)":[88],"100":[90],"mg/dL,":[91,99],"high":[92],"(HDL-C)":[96],"<":[97,277],"40":[98],"triglycerides":[101],"(TG)":[102],"150":[104],"mg/dL.":[105],"Crude":[106],"age-stratified":[108],"proportions":[109],"for":[114,118,137,211,337],"those":[119,274],"obesity":[121,223,266],"estimated.":[123],"Multivariate":[124,254],"analysis":[125,333],"used":[127],"assess":[129],"association":[131],"between":[132,224,293],"obesity,":[135],"controlling":[136],"age,":[138],"gender,":[139],"race/ethnicity,":[140],"wave,":[142],"comorbidities":[144],"(heart":[145],"attack,":[146],"diabetes":[147],"smoking":[149],"status).":[150],"Results":[151],"The":[152],"LDL-C":[156,302],"decreased":[157],"43.5%":[159],"in":[160,165,242,247,313],"36.3%":[164],"1999\u20132006;":[167],"however,":[168],"during":[169],"this":[170,332],"period,":[171],"TG":[176,188,235,289],"HDL-C":[178,237,291],"combined":[179,238],"doubled":[180],"2.1%":[182],"4.8%":[184],"than":[190,209,273],"tripled":[191],"within":[192,251],"elderly":[194],"population":[195,325],"(from":[196],"1.8%":[197],"11.3%).":[199],"It":[200],"estimated":[202],"that":[203],"antidyslipidemic":[204],"medication":[205],"use":[206],"less":[208],"2.6%":[210],"throughout":[215],"study":[216],"period.":[217],"With":[218],"increased":[220,239,292],"\u20132006,":[230],"3.8%":[241],"6.5%":[246],"\u20132006":[250],"obese":[252,320],"adults.":[253],"analyses":[255],"significant":[261],"(p<":[262],"0.001).":[263],"likely":[269],"have":[271],"25":[278],"[OR=2.9,":[281],"(95%":[282],"CI:":[283],"2.7\u20133.2)].":[284],"Conclusions":[285],"Prevalence":[286],"and/or":[290],"1999\u20132006":[298],"although":[299],"shows":[303],"an":[304],"optimistic":[305],"trend.":[306],"This":[307],"paralleled":[309],"by":[310],"shift":[312],"distribution":[315],"toward":[318],"category.":[321],"As":[322],"is":[326],"aging":[327],"becoming":[329],"obese,":[331],"underscores":[334],"need":[336],"renewed":[338],"public":[339],"health":[340],"efforts":[341],"treating":[345],"multiple":[346],"preventing":[351],"via":[353],"body":[354],"mass":[355],"control.":[356]},"counts_by_year":[],"updated_date":"2026-10-24T09:50:30.924529","created_date":"2016-06-24T00:00:00"}