{"id":"https://openalex.org/W129357877","doi":null,"title":"Advanced glycated human serum albumin as AGE-carrier protein in enzyme-linked immunosorbent assay.","display_name":"Advanced glycated human serum albumin as AGE-carrier protein in enzyme-linked immunosorbent assay.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W129357877","mag":"129357877","pmid":"https://pubmed.ncbi.nlm.nih.gov/19097490"},"language":"en","primary_location":{"id":"pmid:19097490","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19097490","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical laboratory","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089874071","display_name":"Bojan Benko","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bojan Benko","raw_affiliation_strings":["State Intellectual Property Office, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Intellectual Property Office, Zagreb, Croatia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111865430","display_name":"Zdenka Turk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zdenka Turk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0177305,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"54","issue":"9-10","first_page":"331","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-glycation-end-products","display_name":"advanced glycation end products","score":0.9950000047683716},{"id":"https://openalex.org/keywords/human-serum-albumin","display_name":"human serum albumin","score":0.9390000104904175},{"id":"https://openalex.org/keywords/competitive-elisa","display_name":"competitive ELISA","score":0.9620000123977661},{"id":"https://openalex.org/keywords/ph-effect","display_name":"pH effect","score":0.6539999842643738},{"id":"https://openalex.org/keywords/glycation","display_name":"glycation","score":0.921999990940094},{"id":"https://openalex.org/keywords/immunoreactivity","display_name":"immunoreactivity","score":0.5979999899864197},{"id":"https://openalex.org/keywords/serum-proteins","display_name":"serum proteins","score":0.3140000104904175}],"concepts":[{"id":"https://openalex.org/C147990577","wikidata":"https://www.wikidata.org/wiki/Q25790","display_name":"Glycation","level":3,"score":0.8559159636497498},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7263956665992737},{"id":"https://openalex.org/C2778597219","wikidata":"https://www.wikidata.org/wiki/Q11721976","display_name":"Human serum albumin","level":2,"score":0.7169240117073059},{"id":"https://openalex.org/C956191","wikidata":"https://www.wikidata.org/wiki/Q930144","display_name":"Polyclonal antibodies","level":3,"score":0.6945145726203918},{"id":"https://openalex.org/C165616093","wikidata":"https://www.wikidata.org/wiki/Q424232","display_name":"Serum albumin","level":2,"score":0.5926597118377686},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.592329740524292},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.5235861539840698},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.505695104598999},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5031883120536804},{"id":"https://openalex.org/C193363816","wikidata":"https://www.wikidata.org/wiki/Q1617865","display_name":"Size-exclusion chromatography","level":3,"score":0.49115511775016785},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4853271543979645},{"id":"https://openalex.org/C2776997535","wikidata":"https://www.wikidata.org/wiki/Q2556837","display_name":"Advanced glycation end-product","level":4,"score":0.48315638303756714},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.43476101756095886},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4089425504207611},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.35912859439849854},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1979999840259552},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17280647158622742},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1271153688430786},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000075462","descriptor_name":"Serum Albumin, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012260","descriptor_name":"Ribonucleases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D017127","descriptor_name":"Glycation End Products, Advanced","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D017127","descriptor_name":"Glycation End Products, Advanced","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:19097490","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19097490","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical laboratory","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W28432897","https://openalex.org/W150772031","https://openalex.org/W1483156553","https://openalex.org/W1609735481","https://openalex.org/W1797161917","https://openalex.org/W1975057327","https://openalex.org/W1975677839","https://openalex.org/W1978793468","https://openalex.org/W1994051814","https://openalex.org/W2024428227","https://openalex.org/W2033274423","https://openalex.org/W2059736408","https://openalex.org/W2061892874","https://openalex.org/W2075422811","https://openalex.org/W2077319761","https://openalex.org/W2080170077","https://openalex.org/W2091966929","https://openalex.org/W2138774341","https://openalex.org/W2148759943","https://openalex.org/W2165179204","https://openalex.org/W2336388442","https://openalex.org/W2471605942"],"related_works":["https://openalex.org/W2789491643","https://openalex.org/W2361637522","https://openalex.org/W56867288","https://openalex.org/W4411689323","https://openalex.org/W2362669377","https://openalex.org/W2083856205","https://openalex.org/W2750846949","https://openalex.org/W4231893197","https://openalex.org/W2782189264","https://openalex.org/W2330517222"],"abstract_inverted_index":{"Competitive":[0],"ELISAs":[1],"for":[2],"advanced":[3],"glycation":[4,139],"end":[5],"product":[6],"(AGE)":[7],"measurements":[8],"are":[9],"based":[10],"on":[11,51,93,137],"anti-AGE-antibody":[12],"and":[13,30,64,80],"in":[14,81],"vitro":[15,82],"prepared":[16,24,83,111,123],"AGE-carrier":[17],"competitive":[18,37,73,148],"antigen.":[19,38],"AGE-human":[20],"serum":[21,101],"albumin":[22],"(HSA)":[23],"by":[25,59,77,118],"non-enzymatic":[26],"reaction":[27],"between":[28],"protein":[29],"glucose":[31],"is":[32],"often":[33],"used":[34],"as":[35],"a":[36],"The":[39,54,103],"aim":[40],"of":[41,49,56,69,100,135,147],"the":[42,47,94,109,133,138,145],"study":[43],"was":[44,75,106],"to":[45,97],"examine":[46],"impact":[48,92,134],"pH":[50,86,113,125,136],"AGE-HSA":[52,57,84,88],"preparation.":[53],"sets":[55],"analyzed":[58],"gel":[60],"filtration":[61],"chromatography,":[62],"IEF":[63],"UV/VIS":[65],"showed":[66,90],"significant":[67],"modifications":[68],"native":[70],"albumin.":[71],"A":[72],"ELISA":[74,95,149],"developed":[76],"using":[78],"polyclonal-AGE-antibody":[79],"at":[85,112,124],"4.5-8.0.":[87],"preparations":[89],"an":[91],"ability":[96],"recognize":[98],"AGE-immunoreactivity":[99,105],"proteins.":[102],"highest":[104],"recorded":[107],"with":[108,121],"antigen":[110],"4.5;":[114],"detection":[115],"limit":[116],"declined":[117],"approximately":[119],"50%":[120],"antigens":[122],"6.5,":[126],"7.5":[127],"or":[128],"8.0.":[129],"Study":[130],"results":[131,146],"confirmed":[132],"adduct":[140],"formation,":[141],"thus":[142],"significantly":[143],"modifying":[144],"measurements.":[150]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}