{"id":"https://openalex.org/W129355265","doi":"https://doi.org/10.1016/b978-0-12-380916-2.00009-7","title":"Rethinking Pediatric Gliomas as Developmental Brain Abnormalities","display_name":"Rethinking Pediatric Gliomas as Developmental Brain Abnormalities","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W129355265","doi":"https://doi.org/10.1016/b978-0-12-380916-2.00009-7","mag":"129355265","pmid":"https://pubmed.ncbi.nlm.nih.gov/21295690"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-380916-2.00009-7","doi":"https://doi.org/10.1016/b978-0-12-380916-2.00009-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-380916-2.00009-7","pdf_url":null,"source":{"id":"https://openalex.org/S36555808","display_name":"Current topics in developmental biology/Current Topics in Developmental Biology","issn_l":"0070-2153","issn":["0070-2153","1557-8933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Developmental Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W651084229","display_name":"Cancer and Development"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021119105","display_name":"Nikkilina R. Crouse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nikkilina R. Crouse","raw_affiliation_strings":["Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA","Department of Neurology Washington University School of Medicine, St. Louis, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Neurology Washington University School of Medicine, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000563525","display_name":"Sonika M Dahiya","orcid":"https://orcid.org/0000-0002-5585-0964","observed_orcids":["https://orcid.org/0000-0002-5585-0964"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sonika Dahiya","raw_affiliation_strings":["Department of Pathology, Washington University School of Medicine, St. Louis, Missouri, USA","Department of Pathology, Washington University School of Medicine, St. Louis, Missouri USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Washington University School of Medicine, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Pathology, Washington University School of Medicine, St. Louis, Missouri USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065106421","display_name":"David H. Gutmann","orcid":"https://orcid.org/0000-0002-3127-5045","observed_orcids":["https://orcid.org/0000-0002-3127-5045"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David H. Gutmann","raw_affiliation_strings":["Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA","Department of Neurology Washington University School of Medicine, St. Louis, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Neurology Washington University School of Medicine, St. Louis, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":3.4568,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.91807542,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"94","issue":null,"first_page":"283","last_page":"308"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11173","display_name":"Neurofibromatosis and Schwannoma Cases","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pediatric-glioma","display_name":"pediatric glioma","score":0.9800000190734863},{"id":"https://openalex.org/keywords/astrocytoma","display_name":"astrocytoma","score":0.8109999895095825},{"id":"https://openalex.org/keywords/neurofibromatosis-type-1","display_name":"neurofibromatosis type 1","score":0.972000002861023},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.8199999928474426},{"id":"https://openalex.org/keywords/stromal-cells","display_name":"stromal cells","score":0.781000018119812},{"id":"https://openalex.org/keywords/tumor-growth","display_name":"tumor growth","score":0.35499998927116394},{"id":"https://openalex.org/keywords/preneoplastic-cells","display_name":"preneoplastic cells","score":0.8080000281333923},{"id":"https://openalex.org/keywords/tumor-cell-interactions","display_name":"tumor cell interactions","score":0.3529999852180481}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8146308660507202},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.7123026847839355},{"id":"https://openalex.org/C15224491","wikidata":"https://www.wikidata.org/wiki/Q7169338","display_name":"Permissive","level":2,"score":0.6973070502281189},{"id":"https://openalex.org/C2778984943","wikidata":"https://www.wikidata.org/wiki/Q847605","display_name":"Neurofibromatosis","level":2,"score":0.6871089935302734},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.5721198320388794},{"id":"https://openalex.org/C52124034","wikidata":"https://www.wikidata.org/wiki/Q557179","display_name":"Stroma","level":3,"score":0.45045214891433716},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4301702678203583},{"id":"https://openalex.org/C2778880634","wikidata":"https://www.wikidata.org/wiki/Q177755","display_name":"Astrocytoma","level":3,"score":0.4160638451576233},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.41252806782722473},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3342587351799011},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2576034665107727},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17369598150253296},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12445127964019775},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/b978-0-12-380916-2.00009-7","doi":"https://doi.org/10.1016/b978-0-12-380916-2.00009-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-380916-2.00009-7","pdf_url":null,"source":{"id":"https://openalex.org/S36555808","display_name":"Current topics in developmental biology/Current Topics in Developmental Biology","issn_l":"0070-2153","issn":["0070-2153","1557-8933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Developmental Biology","raw_type":"book-chapter"},{"id":"pmid:21295690","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21295690","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current topics in developmental biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"sustainable_development_goals_aurora":[{"display_name":"Life on land","id":"https://metadata.un.org/sdg/15","score":0.699999988079071}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":130,"referenced_works":["https://openalex.org/W199447113","https://openalex.org/W1480357432","https://openalex.org/W1495551511","https://openalex.org/W1560814177","https://openalex.org/W1567873511","https://openalex.org/W1576600078","https://openalex.org/W1596721271","https://openalex.org/W1600123087","https://openalex.org/W1651539757","https://openalex.org/W1673160816","https://openalex.org/W1871911763","https://openalex.org/W1930700863","https://openalex.org/W1970574581","https://openalex.org/W1971442377","https://openalex.org/W1971602793","https://openalex.org/W1974408717","https://openalex.org/W1977267072","https://openalex.org/W1980787482","https://openalex.org/W1981711832","https://openalex.org/W1983033726","https://openalex.org/W1985214132","https://openalex.org/W1986758971","https://openalex.org/W1988338260","https://openalex.org/W1992791907","https://openalex.org/W1995607634","https://openalex.org/W1996539839","https://openalex.org/W1996778863","https://openalex.org/W1999879982","https://openalex.org/W2001396896","https://openalex.org/W2001620613","https://openalex.org/W2003506162","https://openalex.org/W2005768105","https://openalex.org/W2006979538","https://openalex.org/W2007194256","https://openalex.org/W2008077459","https://openalex.org/W2008471038","https://openalex.org/W2009441755","https://openalex.org/W2012626714","https://openalex.org/W2012696125","https://openalex.org/W2014006702","https://openalex.org/W2015396002","https://openalex.org/W2016042686","https://openalex.org/W2017090190","https://openalex.org/W2019128864","https://openalex.org/W2019349725","https://openalex.org/W2020231002","https://openalex.org/W2020417669","https://openalex.org/W2021308032","https://openalex.org/W2021448795","https://openalex.org/W2022971724","https://openalex.org/W2023287528","https://openalex.org/W2025238642","https://openalex.org/W2030171190","https://openalex.org/W2031671747","https://openalex.org/W2034029713","https://openalex.org/W2034053511","https://openalex.org/W2039382551","https://openalex.org/W2041609008","https://openalex.org/W2044282514","https://openalex.org/W2044356784","https://openalex.org/W2048140690","https://openalex.org/W2048898424","https://openalex.org/W2049222757","https://openalex.org/W2050168827","https://openalex.org/W2051082355","https://openalex.org/W2052432571","https://openalex.org/W2054318886","https://openalex.org/W2054674800","https://openalex.org/W2057835981","https://openalex.org/W2057839285","https://openalex.org/W2058233029","https://openalex.org/W2059986841","https://openalex.org/W2062809578","https://openalex.org/W2065633693","https://openalex.org/W2066441128","https://openalex.org/W2071893342","https://openalex.org/W2072478579","https://openalex.org/W2073355522","https://openalex.org/W2073998405","https://openalex.org/W2075878390","https://openalex.org/W2077203214","https://openalex.org/W2077377303","https://openalex.org/W2077858999","https://openalex.org/W2082630330","https://openalex.org/W2086520244","https://openalex.org/W2086618165","https://openalex.org/W2095900053","https://openalex.org/W2102726935","https://openalex.org/W2103711259","https://openalex.org/W2105164395","https://openalex.org/W2109063774","https://openalex.org/W2109969209","https://openalex.org/W2112057120","https://openalex.org/W2115516291","https://openalex.org/W2116056936","https://openalex.org/W2116605894","https://openalex.org/W2117558653","https://openalex.org/W2118119833","https://openalex.org/W2119368326","https://openalex.org/W2123383209","https://openalex.org/W2125433565","https://openalex.org/W2126062426","https://openalex.org/W2128994172","https://openalex.org/W2130521145","https://openalex.org/W2130737806","https://openalex.org/W2134201967","https://openalex.org/W2138426514","https://openalex.org/W2138919043","https://openalex.org/W2143089870","https://openalex.org/W2143619463","https://openalex.org/W2143868113","https://openalex.org/W2144283038","https://openalex.org/W2149506749","https://openalex.org/W2149714164","https://openalex.org/W2151067616","https://openalex.org/W2152165396","https://openalex.org/W2152387543","https://openalex.org/W2161289668","https://openalex.org/W2161737261","https://openalex.org/W2162372366","https://openalex.org/W2163720536","https://openalex.org/W2167022467","https://openalex.org/W2169438753","https://openalex.org/W2319887569","https://openalex.org/W2339678451","https://openalex.org/W2396746017","https://openalex.org/W4293026333","https://openalex.org/W6639179960","https://openalex.org/W6652561266","https://openalex.org/W6678398186"],"related_works":["https://openalex.org/W2118512822","https://openalex.org/W2152678253","https://openalex.org/W4311090678","https://openalex.org/W13526662","https://openalex.org/W4210463230","https://openalex.org/W2996143244","https://openalex.org/W3090890720","https://openalex.org/W2120343071","https://openalex.org/W2093548930","https://openalex.org/W3208178658"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}