{"id":"https://openalex.org/W129184406","doi":null,"title":"Immune response of olive flounder, Paralichthys oliveceus against B-hemolytic Streptococcus ineae formalin-killed cells","display_name":"Immune response of olive flounder, Paralichthys oliveceus against B-hemolytic Streptococcus ineae formalin-killed cells","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W129184406","mag":"129184406"},"language":"en","primary_location":{"id":"mag:129184406","doi":null,"is_oa":false,"landing_page_url":"https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001165964","pdf_url":null,"source":{"id":"https://openalex.org/S4210193422","display_name":"Journal of fish pathology","issn_l":"1226-0819","issn":["1226-0819","2233-5412"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"JOURNAL OF FISH PATHOLOGY","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Mi-Young Jo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mi-Young Jo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115588944","display_name":"Deok-Chan Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Deok-Chan Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100434596","display_name":"Jinwoo Kim","orcid":"https://orcid.org/0000-0002-3397-1247","observed_orcids":["https://orcid.org/0000-0002-3397-1247"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jinwoo Kim","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3397-1247","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046282774","display_name":"Ju-Seok Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ju-Seok Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103171898","display_name":"Hee-Jung Choi","orcid":"https://orcid.org/0000-0002-7149-7398","observed_orcids":["https://orcid.org/0000-0002-7149-7398"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hee-Jung Choi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7149-7398","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2401,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.53026984,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"19","issue":"1","first_page":"73","last_page":"82"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/olive-flounder","display_name":"Paralichthys olivaceus","score":0.996999979019165},{"id":"https://openalex.org/keywords/streptococcus-iniae","display_name":"Streptococcus iniae","score":0.9959999918937683},{"id":"https://openalex.org/keywords/formalin-killed-vaccine","display_name":"formalin-killed vaccine","score":0.875},{"id":"https://openalex.org/keywords/fish-vaccines","display_name":"fish vaccines","score":0.3529999852180481},{"id":"https://openalex.org/keywords/antibody-titers","display_name":"antibody titers","score":0.7519999742507935},{"id":"https://openalex.org/keywords/booster-vaccination","display_name":"booster vaccination","score":0.8960000276565552},{"id":"https://openalex.org/keywords/protection-against-challenge","display_name":"challenge protection","score":0.6610000133514404},{"id":"https://openalex.org/keywords/relative-percent-survival","display_name":"relative percent survival","score":0.7749999761581421}],"concepts":[{"id":"https://openalex.org/C2776533291","wikidata":"https://www.wikidata.org/wiki/Q1322753","display_name":"Olive flounder","level":3,"score":0.8408147096633911},{"id":"https://openalex.org/C2776459645","wikidata":"https://www.wikidata.org/wiki/Q3011327","display_name":"Paralichthys","level":3,"score":0.8117095232009888},{"id":"https://openalex.org/C2778815482","wikidata":"https://www.wikidata.org/wiki/Q7623354","display_name":"Streptococcus iniae","level":3,"score":0.7257002592086792},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5818930268287659},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5653008222579956},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5535179972648621},{"id":"https://openalex.org/C22889606","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Antibody titer","level":4,"score":0.5485974550247192},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.5250482559204102},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5007462501525879},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.46074002981185913},{"id":"https://openalex.org/C12590561","wikidata":"https://www.wikidata.org/wiki/Q2920497","display_name":"Booster dose","level":4,"score":0.45255768299102783},{"id":"https://openalex.org/C2776367567","wikidata":"https://www.wikidata.org/wiki/Q4246303","display_name":"Flounder","level":3,"score":0.4205140769481659},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.36897996068000793},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34987735748291016},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.23684686422348022}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:129184406","doi":null,"is_oa":false,"landing_page_url":"https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001165964","pdf_url":null,"source":{"id":"https://openalex.org/S4210193422","display_name":"Journal of fish pathology","issn_l":"1226-0819","issn":["1226-0819","2233-5412"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"JOURNAL OF FISH PATHOLOGY","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.4359000027179718}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W102425714","https://openalex.org/W113538203","https://openalex.org/W1491291048","https://openalex.org/W1967660544","https://openalex.org/W1971427480","https://openalex.org/W1973763036","https://openalex.org/W1980995255","https://openalex.org/W1992596941","https://openalex.org/W1992949522","https://openalex.org/W2015827285","https://openalex.org/W2043010764","https://openalex.org/W2046323146","https://openalex.org/W2060547213","https://openalex.org/W2078656288","https://openalex.org/W2095372957","https://openalex.org/W2128513613","https://openalex.org/W2160297458","https://openalex.org/W2316886890","https://openalex.org/W2521435901"],"related_works":["https://openalex.org/W2343073296","https://openalex.org/W2338033364","https://openalex.org/W2362906169","https://openalex.org/W7222847246","https://openalex.org/W2370071483","https://openalex.org/W1985963042","https://openalex.org/W3121091604","https://openalex.org/W2365081054","https://openalex.org/W2232410730","https://openalex.org/W4401992456"],"abstract_inverted_index":{"Streptococcal":[0],"infections":[1],"were":[2,33,52,82,104,130],"considered":[3],"as":[4],"a":[5,42],"serious":[6],"problem":[7],"because":[8],"of":[9,21,46,57,65,78,87,93,127,144,162,179,207,210],"significant":[10,72],"economic":[11],"losses":[12],"in":[13,25,141],"fish":[14,168],"farm":[15],"industry.":[16],"We":[17],"evaluated":[18],"the":[19,58,66,94,124,133,136,145,157,177,194,204],"efficacies":[20],"Streptococcus":[22],"iniae":[23,201],"vaccines":[24,32,60,67],"olive":[26],"flounder,":[27],"Par-":[28],"alichthys":[29],"olivaceus.":[30],"The":[31,75],"prepared":[34],"from":[35],"10%":[36],"neutral":[37],"buffered":[38],"formalin":[39,98,211],"to":[40,70,97,188],"give":[41],"final":[43],"concen-":[44],"tration":[45],"0.3%":[47,151],"or":[48,62,154,174],"3%,":[49],"respectively.":[50,122,166,183],"Fish":[51,148],"immunized":[53,80,89,149,169],"by":[54,106,132],"intraperitoneal":[55],"injection":[56],"experimental":[59],"once":[61,153,173],"twice.":[63],"Neither":[64],"gave":[68],"rise":[69],"any":[71],"side":[73,205],"effects.":[74],"antibody":[76,102,128,195],"titers":[77,103,196],"booster":[79,120],"groups":[81,90],"significantly":[83,100],"higher":[84],"than":[85],"those":[86],"prime":[88,118],"with":[91,150,170],"both":[92,146],"vaccines.":[95,147],"According":[96],"dosage,":[99],"increased":[101],"produced":[105],"3%":[107,171],"formalin-killed":[108],"cells":[109],"(FKC)":[110],"at":[111],"4":[112],"weeks":[113,116],"and":[114,119,164,181,197],"8":[115],"after":[117],"vaccination,":[121],"Although":[123],"different":[125],"levels":[126],"production":[129],"showed":[131],"vaccinated":[134],"fish,":[135],"good":[137],"protec-":[138],"tion":[139],"obtained":[140],"challenge":[142],"trials":[143],"FKC":[152,172],"twice":[155,175],"had":[156,176],"relative":[158],"percent":[159],"survival":[160],"(RPS)":[161],"66.7%":[163],"87.5%,":[165],"Similarly,":[167],"RPS":[178,198],"70.0%":[180],"77.0%,":[182],"Further":[184],"experiments":[185],"are":[186],"needed":[187],"study":[189],"not":[190],"only":[191],"correlation":[192],"between":[193],"against":[199],"S.":[200],"but":[202],"also":[203],"effects":[206],"high":[208],"dose":[209],"on":[212],"antigenicity.":[213]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}