{"id":"https://openalex.org/W126976492","doi":null,"title":"Neurobiologic and psychobiologic mechanisms in gastric function and ulceration.","display_name":"Neurobiologic and psychobiologic mechanisms in gastric function and ulceration.","publication_year":1985,"publication_date":"1985-08-01","ids":{"openalex":"https://openalex.org/W126976492","mag":"126976492","pmid":"https://pubmed.ncbi.nlm.nih.gov/2863896","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1306273"},"language":"en","primary_location":{"id":"pmid:2863896","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2863896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Western journal of medicine","raw_type":"Journal Article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1306273/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110069125","display_name":"Herbert Weiner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Weiner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066710917","display_name":"Donald Novin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Novin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013962602","display_name":"Carlos V. Grijalva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C V Grijalva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010241733","display_name":"Yvette Tach\u00e9","orcid":"https://orcid.org/0000-0002-1044-5279","observed_orcids":["https://orcid.org/0000-0002-1044-5279"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Tach\u00e9","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111464180","display_name":"Thomas Garrick","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Garrick","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2622,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.26190476,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"143","issue":"2","first_page":"207","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.6723999977111816,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.6723999977111816,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.1729000061750412,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.13230000436306,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastric-acid-secretion","display_name":"gastric acid secretion","score":0.9819999933242798},{"id":"https://openalex.org/keywords/gastric-ulcer","display_name":"gastric ulcer","score":0.7879999876022339},{"id":"https://openalex.org/keywords/gastric-erosions","display_name":"gastric erosions","score":0.8159999847412109},{"id":"https://openalex.org/keywords/feeding-behavior","display_name":"feeding behavior","score":0.9240000247955322},{"id":"https://openalex.org/keywords/lateral-hypothalamus","display_name":"lateral hypothalamus","score":0.8159999847412109},{"id":"https://openalex.org/keywords/vagotomy","display_name":"vagotomy","score":0.8960000276565552},{"id":"https://openalex.org/keywords/propantheline-bromide","display_name":"propantheline bromide","score":0.9290000200271606},{"id":"https://openalex.org/keywords/gastric-mucosal-barrier","display_name":"gastric mucosal barrier","score":0.8230000138282776},{"id":"https://openalex.org/keywords/neuropeptides","display_name":"neuropeptides","score":0.859000027179718},{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"autonomic nervous system","score":0.9150000214576721},{"id":"https://openalex.org/keywords/thyrotropin-releasing-hormone","display_name":"thyrotropin-releasing hormone","score":0.9490000009536743},{"id":"https://openalex.org/keywords/body-temperature","display_name":"body temperature","score":0.8450000286102295},{"id":"https://openalex.org/keywords/food-intake-regulation","display_name":"food intake regulation","score":0.5139999985694885},{"id":"https://openalex.org/keywords/gastric-motility","display_name":"gastric motility","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C2777504413","wikidata":"https://www.wikidata.org/wiki/Q846270","display_name":"Gastric acid","level":3,"score":0.8074218034744263},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.6855838298797607},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.6409322023391724},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6045746803283691},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5878072381019592},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4930884540081024},{"id":"https://openalex.org/C55924715","wikidata":"https://www.wikidata.org/wiki/Q7309668","display_name":"Regulation of gastric function","level":4,"score":0.4801004230976105},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.47538673877716064},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.47174131870269775},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.42326292395591736}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001831","descriptor_name":"Body Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005247","descriptor_name":"Feeding Behavior","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:2863896","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2863896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Western journal of medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1306273","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1306273/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"West J Med","raw_type":"Text"},{"id":"mag:126976492","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2863896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1306273","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1306273/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"West J Med","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":104,"referenced_works":["https://openalex.org/W235657979","https://openalex.org/W1419049002","https://openalex.org/W1531104212","https://openalex.org/W1538311832","https://openalex.org/W1578942385","https://openalex.org/W1591447100","https://openalex.org/W1799972237","https://openalex.org/W1845296680","https://openalex.org/W1892790757","https://openalex.org/W1963850215","https://openalex.org/W1966990176","https://openalex.org/W1967015396","https://openalex.org/W1970058812","https://openalex.org/W1972836378","https://openalex.org/W1973332748","https://openalex.org/W1973363641","https://openalex.org/W1974828706","https://openalex.org/W1975196264","https://openalex.org/W1975709498","https://openalex.org/W1975809767","https://openalex.org/W1976268916","https://openalex.org/W1977455068","https://openalex.org/W1978350881","https://openalex.org/W1978893665","https://openalex.org/W1979221373","https://openalex.org/W1981258786","https://openalex.org/W1981596107","https://openalex.org/W1986274902","https://openalex.org/W1987160566","https://openalex.org/W1990286984","https://openalex.org/W1990723779","https://openalex.org/W1993714990","https://openalex.org/W2003193184","https://openalex.org/W2004183780","https://openalex.org/W2011050938","https://openalex.org/W2011811477","https://openalex.org/W2018097667","https://openalex.org/W2021134386","https://openalex.org/W2023707331","https://openalex.org/W2027842060","https://openalex.org/W2029839050","https://openalex.org/W2034603599","https://openalex.org/W2035581625","https://openalex.org/W2036506953","https://openalex.org/W2038883744","https://openalex.org/W2042176727","https://openalex.org/W2044226522","https://openalex.org/W2045230214","https://openalex.org/W2047726411","https://openalex.org/W2049020587","https://openalex.org/W2049997217","https://openalex.org/W2053797053","https://openalex.org/W2054187499","https://openalex.org/W2055146749","https://openalex.org/W2055360599","https://openalex.org/W2056127437","https://openalex.org/W2058677776","https://openalex.org/W2062098928","https://openalex.org/W2065599351","https://openalex.org/W2066530232","https://openalex.org/W2066886083","https://openalex.org/W2067997256","https://openalex.org/W2068554799","https://openalex.org/W2068820507","https://openalex.org/W2070622383","https://openalex.org/W2072017760","https://openalex.org/W2072071294","https://openalex.org/W2072417674","https://openalex.org/W2078013007","https://openalex.org/W2079094885","https://openalex.org/W2081264545","https://openalex.org/W2081296087","https://openalex.org/W2081812023","https://openalex.org/W2085944033","https://openalex.org/W2086620537","https://openalex.org/W2087705876","https://openalex.org/W2091129282","https://openalex.org/W2092554038","https://openalex.org/W2117120766","https://openalex.org/W2138786576","https://openalex.org/W2140285237","https://openalex.org/W2144207965","https://openalex.org/W2161330056","https://openalex.org/W2176371502","https://openalex.org/W2227819704","https://openalex.org/W2265091643","https://openalex.org/W2272073499","https://openalex.org/W2300832093","https://openalex.org/W2315227837","https://openalex.org/W2317409204","https://openalex.org/W2320511563","https://openalex.org/W2326771544","https://openalex.org/W2331343093","https://openalex.org/W2335817366","https://openalex.org/W2394633275","https://openalex.org/W2398037455","https://openalex.org/W2400391065","https://openalex.org/W2402434182","https://openalex.org/W2413973339","https://openalex.org/W2417213317","https://openalex.org/W2443865134","https://openalex.org/W2923997800","https://openalex.org/W4299736849","https://openalex.org/W4302389336"],"related_works":["https://openalex.org/W1975709498","https://openalex.org/W2026898552","https://openalex.org/W2324004232","https://openalex.org/W2058677776","https://openalex.org/W2090577013","https://openalex.org/W2329937858","https://openalex.org/W2037729996","https://openalex.org/W2228966059","https://openalex.org/W2394791882","https://openalex.org/W2016511356"],"abstract_inverted_index":{"The":[0,11,24,39],"initiation":[1],"and":[2,26,37,44,58,72,77,82,164],"termination":[3],"of":[4,19,28,102,108,124,132,152,155],"feeding":[5],"behavior":[6],"are":[7,30,135],"not":[8,146],"fully":[9],"understood.":[10],"stomach":[12],"has":[13],"been":[14],"implicated":[15],"as":[16],"one":[17],"source":[18],"signals":[20],"regulating":[21,48],"food":[22,29,49],"intake.":[23],"sight":[25],"smell":[27],"potent":[31,158],"stimuli":[32],"to":[33,160],"gastric":[34,74,79,119,133,161],"acid":[35,75,89,120,162],"secretion":[36,76,90,121,163],"contraction.":[38],"mouth,":[40],"upper":[41],"gastrointestinal":[42],"tract":[43],"liver":[45],"contain":[46],"receptors":[47],"intake;":[50],"afferent":[51],"information":[52],"passes":[53],"into":[54,59,104],"the":[55,60,69,87,97,109,112,125,150],"brain":[56,61],"stem":[57],"areas.":[62],"Lateral":[63],"hypothalamic":[64],"lesions":[65],"abolish":[66,86],"feeding,":[67],"raise":[68],"body":[70,140],"temperature":[71],"basal":[73],"produce":[78],"erosions.":[80],"Vagotomy":[81],"administering":[83],"propantheline":[84],"bromide":[85],"increased":[88,153],"after":[91],"such":[92],"lesions;":[93],"they":[94],"also":[95],"alter":[96],"mucosal":[98,105],"barrier":[99],"permitting":[100],"diffusion":[101],"protons":[103],"cells.":[106],"Several":[107],"neuropeptides":[110],"via":[111],"central":[113],"nervous":[114,127],"system":[115],"stimulate":[116],"or":[117,145],"inhibit":[118],"through":[122],"modulation":[123],"autonomic":[126],"system.":[128],"Most":[129],"animal":[130],"models":[131],"erosions":[134],"associated":[136],"with":[137],"a":[138],"reduced":[139],"temperature.":[141],"Unknown":[142],"is":[143,149],"whether":[144],"this":[147],"association":[148],"result":[151],"levels":[154],"thyrotropin-releasing":[156],"hormone-a":[157],"stimulus":[159],"erosion":[165],"formation":[166],"when":[167],"injected":[168],"intracisternally.":[169]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}