{"id":"https://openalex.org/W126879072","doi":null,"title":"Vascular remodeling associated with pregnancy","display_name":"Vascular remodeling associated with pregnancy","publication_year":2015,"publication_date":"2015-01-28","ids":{"openalex":"https://openalex.org/W126879072","mag":"126879072"},"language":"en","primary_location":{"id":"pmh:oai:d-scholarship.pitt.edu:23644","doi":null,"is_oa":true,"landing_page_url":"https://d-scholarship.pitt.edu/23644/1/N_Niemczyk_dissertation_dec_2014.pdf","pdf_url":"http://d-scholarship.pitt.edu/23644/1/N_Niemczyk_dissertation_dec_2014.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://d-scholarship.pitt.edu/23644/1/N_Niemczyk_dissertation_dec_2014.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055240825","display_name":"Nancy Anderson Niemczyk","orcid":"https://orcid.org/0000-0003-1094-1210","observed_orcids":["https://orcid.org/0000-0003-1094-1210"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Nancy A. Niemczyk","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1094-1210","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5055240825"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00199958,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-remodeling","display_name":"vascular remodeling","score":0.6919999718666077},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.9940000176429749},{"id":"https://openalex.org/keywords/carotid-artery","display_name":"carotid artery","score":0.7649999856948853},{"id":"https://openalex.org/keywords/intima-media-thickness","display_name":"intima-media thickness","score":0.7519999742507935},{"id":"https://openalex.org/keywords/brachial-artery-distensibility","display_name":"brachial artery distensibility","score":0.9070000052452087},{"id":"https://openalex.org/keywords/arterial-stiffness","display_name":"arterial stiffness","score":0.8930000066757202},{"id":"https://openalex.org/keywords/parity","display_name":"parity","score":0.8230000138282776},{"id":"https://openalex.org/keywords/nulliparity","display_name":"nulliparity","score":0.9229999780654907},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.6399999856948853},{"id":"https://openalex.org/keywords/overweight-women","display_name":"overweight women","score":0.8799999952316284},{"id":"https://openalex.org/keywords/cardiovascular-disease-in-pregnancy","display_name":"cardiovascular disease in pregnancy","score":0.6010000109672546},{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.9279999732971191},{"id":"https://openalex.org/keywords/maternal-cardiovascular-risk","display_name":"maternal cardiovascular risk","score":0.6809999942779541}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8558471202850342},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.7995282411575317},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.7522849440574646},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5236113667488098},{"id":"https://openalex.org/C2777604165","wikidata":"https://www.wikidata.org/wiki/Q503643","display_name":"Brachial artery","level":3,"score":0.5198941230773926},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5016186237335205},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.4673958718776703},{"id":"https://openalex.org/C2781207646","wikidata":"https://www.wikidata.org/wiki/Q707674","display_name":"Uterine artery","level":4,"score":0.44946154952049255},{"id":"https://openalex.org/C2781064879","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Common carotid artery","level":3,"score":0.4491101801395416},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4465941786766052},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4462870955467224},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4380209147930145},{"id":"https://openalex.org/C2987047532","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Carotid arteries","level":2,"score":0.2613745331764221},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.23330166935920715},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.1825627088546753},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:d-scholarship.pitt.edu:23644","doi":null,"is_oa":true,"landing_page_url":"https://d-scholarship.pitt.edu/23644/1/N_Niemczyk_dissertation_dec_2014.pdf","pdf_url":"http://d-scholarship.pitt.edu/23644/1/N_Niemczyk_dissertation_dec_2014.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"mag:126879072","doi":null,"is_oa":false,"landing_page_url":"http://d-scholarship.pitt.edu/23644/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:d-scholarship.pitt.edu:23644","doi":null,"is_oa":true,"landing_page_url":"https://d-scholarship.pitt.edu/23644/1/N_Niemczyk_dissertation_dec_2014.pdf","pdf_url":"http://d-scholarship.pitt.edu/23644/1/N_Niemczyk_dissertation_dec_2014.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W126879072.pdf","grobid_xml":"https://content.openalex.org/works/W126879072.grobid-xml"},"referenced_works_count":89,"referenced_works":["https://openalex.org/W75304703","https://openalex.org/W122349615","https://openalex.org/W306081986","https://openalex.org/W1921406091","https://openalex.org/W1940566475","https://openalex.org/W1966324370","https://openalex.org/W1968160385","https://openalex.org/W1969313157","https://openalex.org/W1970212278","https://openalex.org/W1973836491","https://openalex.org/W1976868429","https://openalex.org/W1978465359","https://openalex.org/W1979282325","https://openalex.org/W1980677382","https://openalex.org/W1983126942","https://openalex.org/W1983360494","https://openalex.org/W1984842636","https://openalex.org/W1985393612","https://openalex.org/W1985814052","https://openalex.org/W1986847177","https://openalex.org/W1989532665","https://openalex.org/W1991792523","https://openalex.org/W1992519606","https://openalex.org/W1996472368","https://openalex.org/W2001427070","https://openalex.org/W2002612440","https://openalex.org/W2006862162","https://openalex.org/W2007578342","https://openalex.org/W2015059379","https://openalex.org/W2015379124","https://openalex.org/W2016475703","https://openalex.org/W2019258522","https://openalex.org/W2029514978","https://openalex.org/W2035953264","https://openalex.org/W2036519431","https://openalex.org/W2042834584","https://openalex.org/W2042950731","https://openalex.org/W2043771561","https://openalex.org/W2049820052","https://openalex.org/W2050743354","https://openalex.org/W2053105549","https://openalex.org/W2056996714","https://openalex.org/W2064852552","https://openalex.org/W2067508496","https://openalex.org/W2073218072","https://openalex.org/W2091786740","https://openalex.org/W2093274439","https://openalex.org/W2094019991","https://openalex.org/W2096796423","https://openalex.org/W2098745241","https://openalex.org/W2101701509","https://openalex.org/W2103237507","https://openalex.org/W2108762011","https://openalex.org/W2109881629","https://openalex.org/W2110922412","https://openalex.org/W2112927272","https://openalex.org/W2115094926","https://openalex.org/W2116404316","https://openalex.org/W2120113415","https://openalex.org/W2120491756","https://openalex.org/W2122034228","https://openalex.org/W2125794932","https://openalex.org/W2125874733","https://openalex.org/W2127995190","https://openalex.org/W2129837832","https://openalex.org/W2133786107","https://openalex.org/W2136486168","https://openalex.org/W2139129761","https://openalex.org/W2143309901","https://openalex.org/W2143420161","https://openalex.org/W2144312201","https://openalex.org/W2147047643","https://openalex.org/W2147829211","https://openalex.org/W2149136975","https://openalex.org/W2150204340","https://openalex.org/W2151389745","https://openalex.org/W2152401910","https://openalex.org/W2152685563","https://openalex.org/W2152765986","https://openalex.org/W2159780487","https://openalex.org/W2160234571","https://openalex.org/W2171712172","https://openalex.org/W2243235382","https://openalex.org/W2263566824","https://openalex.org/W2316167515","https://openalex.org/W2340055652","https://openalex.org/W2917462181","https://openalex.org/W3015544325","https://openalex.org/W3023401627"],"related_works":["https://openalex.org/W1489604964","https://openalex.org/W2143420161","https://openalex.org/W2805438146","https://openalex.org/W1597258351","https://openalex.org/W2236925866","https://openalex.org/W2139521615","https://openalex.org/W4231890802","https://openalex.org/W3210620047","https://openalex.org/W2766195850","https://openalex.org/W39551429"],"abstract_inverted_index":{"Objectives:":[0],"Research":[1],"indicates":[2],"a":[3,25,56,86,97,166],"relationship":[4,15,26,41,102],"between":[5,27,47,103],"pregnancy":[6,28,89,333],"and":[7,29,49,66,77,90,106,115,172,174,191,207,219,227,241,256,264,290],"cardiovascular":[8],"disease,":[9],"but":[10],"the":[11,45,52,68,82,101,110,121,138,179,212,277,298,307,337,341],"cause":[12,309,342],"of":[13,34,51,58,63,71,81,100,109,126,137,162,168,279,310,316,332,339,343],"this":[14,35,40],"is":[16,21,24,37,306],"unknown.":[17],"One":[18],"possible":[19],"explanation":[20],"that":[22,295],"there":[23],"vascular":[30,285,330],"change.":[31],"The":[32,93,131],"objective":[33],"dissertation":[36],"to":[38,142,229,239,253],"illuminate":[39],"by":[42],"exploring":[43],"1)":[44],"association":[46],"parity":[48],"structure":[50],"carotid":[53,73,111,164,187,274],"arteries":[54],"in":[55,79,113,120,147,312],"population":[57],"overweight":[59,114,263],"or":[60],"obese":[61,116,265],"women":[62,118,152,183,201,317],"reproductive":[64,104],"age":[65,218],"2)":[67],"normal":[69,329],"course":[70,278],"common":[72,186],"artery":[74,84,112,170,247],"(CCA)":[75],"remodeling":[76],"changes":[78,286,331],"stiffness":[80],"brachial":[83,169,246,292],"throughout":[85,156],"healthy":[87,150,273,280],"first":[88,94,158,281],"postpartum.":[91,231,260],"Methods:":[92],"paper":[95],"provides":[96],"cross-sectional":[98],"analysis":[99],"factors":[105],"structural":[107],"measures":[108],"young":[117,151,266],"participating":[119],"Slow":[122],"Adverse":[123],"Vascular":[124,140],"Effect":[125],"Obesity":[127],"(SAVE)":[128],"clinical":[129],"trial.":[130],"subsequent":[132],"2":[133],"papers":[134],"provide":[135],"results":[136],"Maternal":[139],"Adaptation":[141],"Healthy":[143],"Pregnancy":[144],"(MVP)":[145],"study,":[146,181,214],"which":[148],"43":[149],"were":[153],"assessed":[154],"prospectively":[155],"their":[157,163],"pregnancies":[159],"with":[160,199,271],"ultrasounds":[161],"arteries,":[165],"measure":[167],"distensibility,":[171],"physical":[173],"metabolic":[175],"measures.":[176],"Results:":[177],"In":[178,211],"SAVE":[180],"nulliparous":[182],"had":[184],"greater":[185],"inter-adventitial":[188],"diameter":[189],"(IAD)":[190],"mean":[192,222],"CCA":[193,233,288],"intima":[194],"media":[195],"thickness":[196],"(IMT)":[197],"compared":[198,238],"parous":[200],"after":[202,215],"adjustment":[203,216],"for":[204,217,325],"age,":[205],"race,":[206],"CVD":[208],"risk":[209,320,326],"factors.":[210],"MVP":[213],"pre-pregnancy":[220],"BMI,":[221],"IAD":[223],"increased":[224,236],"each":[225],"trimester":[226,243,252,255],"returned":[228],"baseline":[230],"Mean":[232,245],"IMT":[234,289],"was":[235,269],"postpartum":[237,299],"1st":[240,251],"2nd":[242],"values.":[244],"distensibility":[248],"decreased":[249],"from":[250],"3rd":[254],"then":[257],"remained":[258],"unchanged":[259],"Conclusions:":[261],"Among":[262],"women,":[267],"nulliparity":[268],"associated":[270],"less":[272],"arteries.":[275],"During":[276],"pregnancy,":[282],"some":[283],"negative":[284],"(greater":[287],"stiffer":[291],"arteries)":[293],"occurred":[294],"persisted":[296],"into":[297],"period.":[300],"Public":[301],"Health":[302],"Significance:":[303],"Cardiovascular":[304],"disease":[305],"leading":[308],"death":[311],"women.":[313],"Early":[314],"identification":[315],"at":[318],"high":[319],"(nulliparous)":[321],"offers":[322],"early":[323],"opportunity":[324],"reduction.":[327],"Understanding":[328],"may":[334],"help":[335],"explain":[336],"pathophysiology":[338],"preeclampsia,":[340],"50,000":[344],"maternal":[345],"deaths":[346],"per":[347],"year.":[348]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}