{"id":"https://openalex.org/W1262681963","doi":null,"title":"Effect of benzodiazepine hypnotics on all-night sleep EEG spectra.","display_name":"Effect of benzodiazepine hypnotics on all-night sleep EEG spectra.","publication_year":1985,"publication_date":"1985-01-01","ids":{"openalex":"https://openalex.org/W1262681963","mag":"1262681963","pmid":"https://pubmed.ncbi.nlm.nih.gov/2866173"},"language":"en","primary_location":{"id":"pmid:2866173","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2866173","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human neurobiology","raw_type":"Clinical Trial"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012903274","display_name":"Alexander A. Borb\u00e9ly","orcid":"https://orcid.org/0000-0002-0115-6141","observed_orcids":["https://orcid.org/0000-0002-0115-6141"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A A Borb\u00e9ly","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035329833","display_name":"P Mattmann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Mattmann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028186981","display_name":"Maija Loepfe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Loepfe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077574062","display_name":"Inge Strauch","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Strauch","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"D Lehmann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Lehmann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1242,"has_fulltext":false,"cited_by_count":230,"citation_normalized_percentile":{"value":0.80147854,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"4","issue":"3","first_page":"189","last_page":"94"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.6172000169754028,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.6172000169754028,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.3513000011444092,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzodiazepine-hypnotics","display_name":"benzodiazepine hypnotics","score":0.9940000176429749},{"id":"https://openalex.org/keywords/flunitrazepam","display_name":"flunitrazepam","score":0.9309999942779541},{"id":"https://openalex.org/keywords/flurazepam","display_name":"flurazepam","score":1.0},{"id":"https://openalex.org/keywords/triazolam","display_name":"triazolam","score":1.0},{"id":"https://openalex.org/keywords/sleep-stages","display_name":"sleep stages","score":0.8790000081062317},{"id":"https://openalex.org/keywords/rem-sleep","display_name":"REM sleep","score":0.9639999866485596},{"id":"https://openalex.org/keywords/stage-2-sleep","display_name":"stage 2 sleep","score":0.6800000071525574},{"id":"https://openalex.org/keywords/sleep-spindles","display_name":"sleep spindles","score":0.9200000166893005},{"id":"https://openalex.org/keywords/residual-drug-effects","display_name":"residual drug effects","score":0.9089999794960022}],"concepts":[{"id":"https://openalex.org/C2779738154","wikidata":"https://www.wikidata.org/wiki/Q412143","display_name":"Triazolam","level":4,"score":0.9300661683082581},{"id":"https://openalex.org/C2781442855","wikidata":"https://www.wikidata.org/wiki/Q62947","display_name":"Flunitrazepam","level":4,"score":0.860936164855957},{"id":"https://openalex.org/C2778173252","wikidata":"https://www.wikidata.org/wiki/Q83871","display_name":"Benzodiazepine","level":3,"score":0.7524865865707397},{"id":"https://openalex.org/C2776156762","wikidata":"https://www.wikidata.org/wiki/Q418998","display_name":"Flurazepam","level":4,"score":0.7163988351821899},{"id":"https://openalex.org/C2778537899","wikidata":"https://www.wikidata.org/wiki/Q254034","display_name":"Bedtime","level":2,"score":0.6662675738334656},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.6471390724182129},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.5919579863548279},{"id":"https://openalex.org/C110539466","wikidata":"https://www.wikidata.org/wiki/Q3964845","display_name":"Slow-wave sleep","level":3,"score":0.516899585723877},{"id":"https://openalex.org/C2910364982","wikidata":"https://www.wikidata.org/wiki/Q35831","display_name":"Sleep Stages","level":4,"score":0.5148619413375854},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.44651687145233154},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.43741345405578613},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32822781801223755},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3032262325286865},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.1472872495651245},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.13472455739974976},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005445","descriptor_name":"Flunitrazepam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005479","descriptor_name":"Flurazepam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012894","descriptor_name":"Sleep Stages","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012894","descriptor_name":"Sleep Stages","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014151","descriptor_name":"Anti-Anxiety Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014229","descriptor_name":"Triazolam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2866173","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2866173","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human neurobiology","raw_type":"Clinical Trial"},{"id":"mag:1262681963","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2866173","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8600000143051147}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2004288951","https://openalex.org/W2085540309","https://openalex.org/W141397220","https://openalex.org/W1994787382","https://openalex.org/W2046569873","https://openalex.org/W2097351421","https://openalex.org/W2047553923","https://openalex.org/W2126636144","https://openalex.org/W2089265206","https://openalex.org/W164364704"],"abstract_inverted_index":{"The":[0,184],"effect":[1],"of":[2,8,51,64,72,83,89,155,161,181],"a":[3,87],"single,":[4],"oral":[5],"bedtime":[6],"dose":[7],"the":[9,26,30,43,49,62,77,84,111,115,120,138,152,156,159,178,182,194,199],"benzodiazepine":[10,188],"hypnotics":[11,189],"flunitrazepam":[12],"(FR;":[13,17],"2":[14,131,166],"mg),":[15,19],"flurazepam":[16],"30":[18],"and":[20,29,54,60,69,100,132,148,201],"triazolam":[21],"(TR;":[22],"0.5":[23],"mg)":[24],"on":[25],"sleep":[27,31,147,209],"stages":[28,95],"EEG":[32,85,195],"was":[33,126,167],"investigated":[34],"in":[35,76,94,110,119,129,137,145,164,177,193],"eight":[36],"healthy,":[37],"young":[38],"subjects.":[39],"In":[40,114,151],"comparison":[41],"to":[42],"placebo":[44],"night,":[45,158],"all":[46,107],"drugs":[47,109],"reduced":[48],"percentage":[50],"stage":[52,58,65,130,149,165],"1":[53],"REM":[55,101,146],"sleep,":[56,102],"increased":[57],"2,":[59,96],"decreased":[61],"number":[63],"shifts.":[66],"For":[67],"FN":[68],"FR,":[70],"some":[71],"these":[73],"changes":[74,103,192],"persisted":[75,105],"postdrug":[78],"night.":[79,113,183],"All-night":[80],"spectral":[81],"analysis":[82],"showed":[86],"reduction":[88],"low-frequency":[90,162],"activity":[91,118,136,163],"(0.25-10.0":[92],"Hz)":[93,125,143],"3":[97,133],"+":[98,134],"4":[99],"that":[104,187],"for":[106],"three":[108],"post-drug":[112],"drug":[116,157,203],"nights,":[117],"spindle":[121],"frequency":[122,140],"range":[123,141],"(11-14":[124],"enhanced":[127],"particularly":[128,144],"4,":[135],"high":[139],"(17-25":[142],"1.":[150],"first":[153],"third":[154],"depression":[160],"either":[168],"absent":[169],"(FR)":[170],"or":[171],"less":[172],"prominent":[173],"(FN,":[174],"TR)":[175],"than":[176,207],"following":[179],"part":[180],"results":[185],"demonstrate":[186],"induce":[190],"specific":[191],"spectra":[196],"which":[197],"reflect":[198],"immediate":[200],"residual":[202],"effects":[204],"more":[205],"sensitively":[206],"conventional":[208],"scores.":[210]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}