{"id":"https://openalex.org/W122050792","doi":null,"title":"Intersegmental fusion in vertebrate rod photoreceptors. Rod cell structure revisited.","display_name":"Intersegmental fusion in vertebrate rod photoreceptors. Rod cell structure revisited.","publication_year":1995,"publication_date":"1995-08-01","ids":{"openalex":"https://openalex.org/W122050792","mag":"122050792","pmid":"https://pubmed.ncbi.nlm.nih.gov/7635665"},"language":"en","primary_location":{"id":"pmid:7635665","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7635665","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108131824","display_name":"Ellen Townes\u2010Anderson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"E Townes-Anderson","raw_affiliation_strings":["Department of Physiology and Biophysics, Cornell University Medical College, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics, Cornell University Medical College, New York, New York, USA","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108131824"],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":null,"apc_paid":null,"fwci":0.3602,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.49310624,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"36","issue":"9","first_page":"1918","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.6323000192642212,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.6323000192642212,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.33719998598098755,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rod-photoreceptors","display_name":"rod photoreceptors","score":0.9959999918937683},{"id":"https://openalex.org/keywords/inner-segment","display_name":"inner segment","score":0.6290000081062317},{"id":"https://openalex.org/keywords/outer-segment","display_name":"outer segment","score":0.9990000128746033},{"id":"https://openalex.org/keywords/membrane-fusion","display_name":"membrane fusion","score":0.8100000023841858},{"id":"https://openalex.org/keywords/retinal-detachment","display_name":"retinal detachment","score":0.8769999742507935},{"id":"https://openalex.org/keywords/calcium","display_name":"calcium","score":0.4230000078678131},{"id":"https://openalex.org/keywords/temperature-effects","display_name":"temperature effects","score":0.6470000147819519},{"id":"https://openalex.org/keywords/depolarization","display_name":"depolarization","score":0.7799999713897705},{"id":"https://openalex.org/keywords/photoreceptor-ultrastructure","display_name":"photoreceptor ultrastructure","score":0.6970000267028809},{"id":"https://openalex.org/keywords/membrane-fission","display_name":"membrane fission","score":0.5120000243186951},{"id":"https://openalex.org/keywords/salamander-retina","display_name":"salamander retina","score":0.7289999723434448},{"id":"https://openalex.org/keywords/frog-retina","display_name":"frog retina","score":0.9509999752044678},{"id":"https://openalex.org/keywords/rat-retina","display_name":"rat retina","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C103038307","wikidata":"https://www.wikidata.org/wiki/Q6556360","display_name":"Lipid bilayer fusion","level":3,"score":0.6563141345977783},{"id":"https://openalex.org/C92488253","wikidata":"https://www.wikidata.org/wiki/Q56592403","display_name":"Cell fusion","level":3,"score":0.6043441891670227},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.6040271520614624},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5761672854423523},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5449177622795105},{"id":"https://openalex.org/C158525013","wikidata":"https://www.wikidata.org/wiki/Q2593739","display_name":"Fusion","level":2,"score":0.5400539040565491},{"id":"https://openalex.org/C4141045","wikidata":"https://www.wikidata.org/wiki/Q83183","display_name":"Depolarization","level":2,"score":0.5103654265403748},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.48768675327301025},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.4653193950653076},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.4445445239543915},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.35703930258750916},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3289175033569336},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.3032371401786804},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3003436326980591},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20307910442352295},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.06298908591270447},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000557","descriptor_name":"Ambystoma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008561","descriptor_name":"Membrane Fusion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010786","descriptor_name":"Photoreceptor Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010786","descriptor_name":"Photoreceptor Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012163","descriptor_name":"Retinal Detachment","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D014982","descriptor_name":"Xenopus laevis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017948","descriptor_name":"Retinal Rod Photoreceptor Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D017948","descriptor_name":"Retinal Rod Photoreceptor Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017948","descriptor_name":"Retinal Rod Photoreceptor Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:7635665","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7635665","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},{"id":"mag:122050792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7635665","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W79812794","https://openalex.org/W1997019506","https://openalex.org/W1539170644","https://openalex.org/W1835827598","https://openalex.org/W3036528925","https://openalex.org/W2079844971","https://openalex.org/W1965192990","https://openalex.org/W3036393053","https://openalex.org/W7096380615","https://openalex.org/W2120406492"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"determine":[2],"the":[3,10,14,43,63,141,169,185,191,206,248,255],"cause":[4],"of":[5,13,40,45,52,69,124,136,143,171,220,247],"intersegmental":[6],"fusion--a":[7],"fusion":[8,41,97,125,165,199,207,216],"between":[9,190],"plasma":[11],"membranes":[12],"inner":[15,192],"and":[16,29,42,58,72,110,152,193],"outer":[17,194],"segments--in":[18],"vertebrate":[19,221],"rod":[20,99,145,222,256],"cells.":[21,223],"METHODS:":[22],"Rod":[23],"cells":[24,100,173],"from":[25,62,89],"adult":[26],"salamander,":[27],"frog,":[28],"rat":[30],"retinas":[31,60,79,82,130],"were":[32,47,74,93],"examined":[33,75],"with":[34,212],"electron":[35],"microscopy.":[36],"The":[37,67,122,187],"fine":[38],"structure":[39],"frequency":[44],"occurrence":[46],"assessed":[48],"in":[49,76,83,98,104,112,127,174,184],"three":[50],"types":[51],"preparations":[53],"(intact":[54],"eyeballs,":[55],"eyecup":[56,176],"preparations,":[57,177],"neural":[59,78],"detached":[61],"retinal":[64,108,228],"pigmented":[65],"epithelium).":[66],"effects":[68],"temperature,":[70],"depolarization,":[71],"calcium":[73],"isolated":[77,128],"by":[80,182,197,233],"maintaining":[81],"culture":[84],"under":[85],"defined":[86],"conditions.":[87],"Retinas":[88],"anesthetized":[90],"animals":[91],"also":[92],"examined.":[94],"RESULTS:":[95],"Intersegmental":[96,215],"was":[101,131,166],"consistently":[102],"observed":[103],"all":[105],"species":[106],"after":[107,227],"detachment":[109],"maintenance":[111],"a":[113,134,218],"standard":[114],"Ringer's":[115],"solution":[116],"for":[117],"20":[118],"to":[119,133,209],"30":[120],"minutes.":[121],"amount":[123],"seen":[126,167,225],"amphibian":[129,175],"sensitive":[132],"number":[135,142],"factors:":[137],"Elevated":[138],"temperature":[139],"increased":[140,181],"fused":[144,172],"cells,":[146],"whereas":[147],"high":[148],"KCl,":[149],"low":[150],"CaCl2,":[151],"Tricaine,":[153],"which":[154],"has":[155],"calcium-related":[156],"effects,":[157],"reduced":[158],"or":[159],"prevented":[160],"fusion.":[161],"In":[162],"attached":[163],"retinas,":[164],"infrequently;":[168],"incidence":[170],"however,":[178],"could":[179],"be":[180,210,245],"incubation":[183],"cold.":[186],"extensive":[188],"continuity":[189],"segments":[195],"created":[196],"their":[198],"did":[200],"not":[201],"disrupt":[202],"intracellular":[203],"structure.":[204],"Moreover,":[205],"seemed":[208],"reversible":[211],"time.":[213],"CONCLUSIONS:":[214],"is":[217,231],"feature":[219],"Although":[224],"predominantly":[226],"detachment,":[229],"it":[230,243],"influenced":[232],"factors":[234],"that":[235],"affect":[236],"other":[237],"well-known":[238],"exoplasmic":[239],"membrane":[240,251],"fusions.":[241],"Thus,":[242],"may":[244],"one":[246],"many":[249],"regulated":[250],"fusion-fission":[252],"events":[253],"within":[254],"photoreceptor.":[257]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}