{"id":"https://openalex.org/W121345263","doi":null,"title":"En studie av antistoffrespons og depoteffekt ved bruk av partikler med ulik st\u00f8rrelse, molekylvekt og L:G forhold.","display_name":"En studie av antistoffrespons og depoteffekt ved bruk av partikler med ulik st\u00f8rrelse, molekylvekt og L:G forhold.","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W121345263","mag":"121345263"},"language":"nn","primary_location":{"id":"pmh:oai:munin.uit.no:10037/4175","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10037/4175","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/masterThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/10037/4175","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090714309","display_name":"Jostein Grip","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jostein Grip","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5090714309"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.5234000086784363,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.5234000086784363,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.39259999990463257,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plga","display_name":"PLGA","score":0.6399999856948853},{"id":"https://openalex.org/keywords/polylactic-acid","display_name":"polylactic acid","score":0.8050000071525574},{"id":"https://openalex.org/keywords/humoral-immune-response","display_name":"humoral immune response","score":0.7170000076293945},{"id":"https://openalex.org/keywords/vaccine-adjuvants","display_name":"vaccine adjuvants","score":0.6980000138282776},{"id":"https://openalex.org/keywords/human-gamma-globulin","display_name":"human gamma globulin","score":0.703000009059906},{"id":"https://openalex.org/keywords/beta-glucan","display_name":"\u03b2-glucan","score":0.7990000247955322},{"id":"https://openalex.org/keywords/particle-size","display_name":"particle size","score":0.5040000081062317},{"id":"https://openalex.org/keywords/molecular-weight","display_name":"molecular weight","score":0.8849999904632568},{"id":"https://openalex.org/keywords/lactide-glycolide-ratio","display_name":"lactide/glycolide ratio","score":0.8040000200271606},{"id":"https://openalex.org/keywords/tissue-distribution","display_name":"tissue distribution","score":0.5879999995231628},{"id":"https://openalex.org/keywords/antigen-release","display_name":"antigen release","score":0.5080000162124634},{"id":"https://openalex.org/keywords/nanoparticle-encapsulation","display_name":"nanoparticle encapsulation","score":0.4950000047683716},{"id":"https://openalex.org/keywords/atlantic-salmon","display_name":"Atlantic salmon","score":0.7749999761581421},{"id":"https://openalex.org/keywords/fish-vaccination","display_name":"fish vaccination","score":0.4909999966621399},{"id":"https://openalex.org/keywords/immunogenicity","display_name":"immunogenicity","score":0.367000013589859},{"id":"https://openalex.org/keywords/iodine-125","display_name":"iodine-125","score":0.4959999918937683}],"concepts":[{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.372091144323349},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3115718960762024}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:munin.uit.no:10037/4175","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10037/4175","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"mag:121345263","doi":null,"is_oa":false,"landing_page_url":"https://munin.uit.no/bitstream/10037/4175/1/thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2182383452","doi":null,"is_oa":false,"landing_page_url":"https://ub.uit.no/munin/bitstream/10037/4175/1/thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:munin.uit.no:10037/4175","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10037/4175","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/masterThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W586180648","https://openalex.org/W1261650543","https://openalex.org/W1487014217","https://openalex.org/W1964313447","https://openalex.org/W1965399445","https://openalex.org/W1970000136","https://openalex.org/W1977698433","https://openalex.org/W1978876638","https://openalex.org/W1982096781","https://openalex.org/W1985486195","https://openalex.org/W1990223878","https://openalex.org/W2000993433","https://openalex.org/W2004329358","https://openalex.org/W2015218404","https://openalex.org/W2015639818","https://openalex.org/W2022961578","https://openalex.org/W2024088680","https://openalex.org/W2031763448","https://openalex.org/W2035953055","https://openalex.org/W2036999791","https://openalex.org/W2037395882","https://openalex.org/W2047824475","https://openalex.org/W2048274021","https://openalex.org/W2050438864","https://openalex.org/W2052974669","https://openalex.org/W2055208346","https://openalex.org/W2057572412","https://openalex.org/W2058416686","https://openalex.org/W2068021450","https://openalex.org/W2068593367","https://openalex.org/W2069638932","https://openalex.org/W2070194538","https://openalex.org/W2076778560","https://openalex.org/W2081288629","https://openalex.org/W2081365179","https://openalex.org/W2081423126","https://openalex.org/W2082617147","https://openalex.org/W2083407483","https://openalex.org/W2085336378","https://openalex.org/W2089185792","https://openalex.org/W2092070022","https://openalex.org/W2093483924","https://openalex.org/W2094092294","https://openalex.org/W2097751983","https://openalex.org/W2133449490","https://openalex.org/W2143629227","https://openalex.org/W2152367839","https://openalex.org/W2152758574","https://openalex.org/W2159465958","https://openalex.org/W2278233976","https://openalex.org/W2314470992","https://openalex.org/W3143486655"],"related_works":["https://openalex.org/W1243137","https://openalex.org/W183440267","https://openalex.org/W2045106645","https://openalex.org/W2068955837","https://openalex.org/W7217115809","https://openalex.org/W1981836087","https://openalex.org/W2053260887","https://openalex.org/W2025391614","https://openalex.org/W2047788951","https://openalex.org/W1872476862"],"abstract_inverted_index":{"Sammendrag\\nPartikler":[0],"av":[1,67,86,113,117,148,155,160,185,189,205,228],"polymerene":[2],"poly":[3,8],"(lactide-co-glycolide)":[4],"acid":[5,10],"(PLGA)":[6],"og":[7,30,88,105,128,218],"(lactide)":[9],"(PLA)":[11],"har":[12,72,215],"vist":[13],"seg":[14],"\u00e5":[15,26,49,59,221],"v\u00e6re":[16],"effektive":[17],"som":[18,37],"adjuvanter/antigendepot":[19],"i":[20,39,84,99,121,129,141,196,209,224],"musemodeller,":[21],"hvor":[22],"de":[23],"bidrar":[24],"til":[25,52,58,65,203,220],"fremprovosere":[27],"en":[28],"robust":[29],"vedvarende":[31],"antistoffrespons.":[32],"Fremdeles":[33],"er":[34],"PLGA/PLA-partiklenes":[35],"egenskaper":[36,93],"adjuvans":[38],"atlantisk":[40,100,225],"laks":[41,101,226],"lite":[42],"kjent.":[43],"\\nM\u00e5let":[44],"med":[45,81,90,182,191],"dette":[46,210],"studiet":[47,71,211],"var":[48,173],"sammenlikne":[50],"depotegenskapen":[51],"ulike":[53,91,216],"PLGA/PLA-formuleringer,":[54],"samt":[55],"deres":[56],"evne":[57,219],"stimulere":[60],"det":[61],"adaptive":[62],"(humorale)":[63],"immunforsvaret":[64],"produksjon":[66],"spesifikke":[68,149],"antistoffer.":[69,207],"Til":[70],"vi":[73],"koinkapsulert":[74],"et":[75],"modellprotein":[76],"(human":[77],"gamma":[78],"globulin,":[79],"HGG)":[80],"\u03b2-glukan":[82],"(laminaran)":[83],"formuleringer":[85],"PLGA":[87],"PLA":[89],"fysio-kjemiske":[92,230],"(molekylvekt,":[94],"partikkelst\u00f8rrelse,":[95],"melke:glykolsyre":[96],"forhold).\\nPartiklenes":[97],"depoteffekt":[98,199],"ble":[102,119,138,165,194],"unders\u00f8kt":[103],"7":[104],"36":[106],"dager":[107],"etter":[108,136],"intraperitoneal":[109],"injeksjon":[110],"ved":[111,153],"bruk":[112,154],"I125-merket":[114],"HGG.":[115],"Depot/biodistribusjon":[116],"HGG-I125":[118],"m\u00e5lt":[120],"organpakken":[122],"(mage-tarmsystem,":[123],"lever,":[124],"milt),":[125],"muskel,":[126],"nyren":[127],"hele":[130],"fisken.":[131],"I":[132],"perioden":[133],"4-16":[134],"uker":[135,145],"immunisering":[137],"fisken":[139],"blodtappet":[140],"intervaller":[142],"p\u00e5":[143],"2":[144],"for":[146,178],"m\u00e5ling":[147],"antistoffer":[150],"mot":[151],"HGG":[152],"indirekte":[156],"ELISA.\\nIn":[157],"vitro":[158],"inkubering":[159],"partikkelformuleringene":[161,214],"viste":[162],"at":[163,213],"antigen":[164,186],"frigjort":[166],"raskere":[167],"fra":[168,187],"mikropartikler":[169],"enn":[170],"nanopartikler,":[171],"samtidig":[172],"depoteffekten":[174],"in":[175],"vivo":[176],"bedre":[177],"enkelte":[179],"mikropartikkelformuleringer":[180],"sammenliknet":[181],"nanopartikler.":[183],"Akkumulering":[184],"nanopartikler":[188],"polymer":[190],"h\u00f8y":[192],"molekylvekt":[193],"observert":[195],"nyrene.":[197],"Partikkelformuleringenes":[198],"kunne":[200],"ikke":[201],"korreleres":[202],"niv\u00e5et":[204],"HGG-spesifikke":[206],"Funnene":[208],"viser":[212],"depotegenskaper":[217],"fremkalle":[222],"antistoffrespons":[223],"avhengig":[227],"polymerenes":[229],"egenskaper.":[231]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}