{"id":"https://openalex.org/W121021296","doi":null,"title":"Vascular depression: An early indicator of decline","display_name":"Vascular depression: An early indicator of decline","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W121021296","mag":"121021296"},"language":"en","primary_location":{"id":"pmh:oai:digitalcommons.wayne.edu:oa_dissertations-1736","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.wayne.edu/oa_dissertations/737","pdf_url":null,"source":{"id":"https://openalex.org/S171990522","display_name":"Human Biology","issn_l":"0018-7143","issn":["0018-7143","1534-6617"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","erih-plus","jufo-1","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316469","host_organization_name":"Wayne State University Press","host_organization_lineage":["https://openalex.org/P4310316469"],"host_organization_lineage_names":["Wayne State University Press"],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wayne State University Dissertations","raw_type":"dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047389113","display_name":"Daniel L. Paulson","orcid":"https://orcid.org/0000-0002-4299-2437","observed_orcids":["https://orcid.org/0000-0002-4299-2437"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Daniel Paulson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4299-2437","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5047389113"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12811","display_name":"Aging, Health, and Disability","score":0.147599995136261,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.08269999921321869,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-depression","display_name":"vascular depression","score":0.9909999966621399},{"id":"https://openalex.org/keywords/geriatric-depression","display_name":"geriatric depression","score":0.7480000257492065},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.8840000033378601},{"id":"https://openalex.org/keywords/frailty","display_name":"frailty","score":0.8610000014305115},{"id":"https://openalex.org/keywords/brain-reserve","display_name":"brain reserve","score":0.7099999785423279},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.4259999990463257},{"id":"https://openalex.org/keywords/healthy-aging","display_name":"healthy aging","score":0.5210000276565552},{"id":"https://openalex.org/keywords/integrated-care","display_name":"integrated care","score":0.5320000052452087},{"id":"https://openalex.org/keywords/older-women","display_name":"older women","score":0.8270000219345093},{"id":"https://openalex.org/keywords/aging-in-place","display_name":"aging in place","score":0.39800000190734863},{"id":"https://openalex.org/keywords/functional-decline","display_name":"functional decline","score":0.37700000405311584},{"id":"https://openalex.org/keywords/vascular-disease","display_name":"vascular disease","score":0.3190000057220459},{"id":"https://openalex.org/keywords/health-and-retirement-study","display_name":"Health and Retirement Study","score":0.5910000205039978},{"id":"https://openalex.org/keywords/latent-growth-curve-models","display_name":"latent growth curve models","score":0.4519999921321869},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.38199999928474426},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.6190000176429749},{"id":"https://openalex.org/keywords/chronic-comorbidities","display_name":"chronic comorbidities","score":0.6069999933242798},{"id":"https://openalex.org/keywords/functional-independence","display_name":"functional independence","score":0.32600000500679016}],"concepts":[{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.6605772376060486},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3878694176673889},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3566105365753174},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.2346464991569519},{"id":"https://openalex.org/C165556158","wikidata":"https://www.wikidata.org/wiki/Q83937","display_name":"Keynesian economics","level":1,"score":0.08270043134689331}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:digitalcommons.wayne.edu:oa_dissertations-1736","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.wayne.edu/oa_dissertations/737","pdf_url":null,"source":{"id":"https://openalex.org/S171990522","display_name":"Human Biology","issn_l":"0018-7143","issn":["0018-7143","1534-6617"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","erih-plus","jufo-1","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316469","host_organization_name":"Wayne State University Press","host_organization_lineage":["https://openalex.org/P4310316469"],"host_organization_lineage_names":["Wayne State University Press"],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wayne State University Dissertations","raw_type":"dissertation"},{"id":"mag:121021296","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.wayne.edu/cgi/viewcontent.cgi?article=1736&context=oa_dissertations","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.979200005531311}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":164,"referenced_works":["https://openalex.org/W115848647","https://openalex.org/W144734289","https://openalex.org/W165338889","https://openalex.org/W563966646","https://openalex.org/W619790032","https://openalex.org/W657398986","https://openalex.org/W1516486747","https://openalex.org/W1517352381","https://openalex.org/W1526861311","https://openalex.org/W1537840728","https://openalex.org/W1561672229","https://openalex.org/W1746685364","https://openalex.org/W1750611917","https://openalex.org/W1847168837","https://openalex.org/W1965478903","https://openalex.org/W1967235520","https://openalex.org/W1969673584","https://openalex.org/W1975058717","https://openalex.org/W1978465828","https://openalex.org/W1978597088","https://openalex.org/W1979556598","https://openalex.org/W1982324410","https://openalex.org/W1982497009","https://openalex.org/W1983270529","https://openalex.org/W1985499706","https://openalex.org/W1986286400","https://openalex.org/W1987430929","https://openalex.org/W1990077202","https://openalex.org/W1990866527","https://openalex.org/W1995083258","https://openalex.org/W1997741731","https://openalex.org/W2001003353","https://openalex.org/W2001659985","https://openalex.org/W2001890682","https://openalex.org/W2002361530","https://openalex.org/W2002571399","https://openalex.org/W2005133023","https://openalex.org/W2007721897","https://openalex.org/W2008679344","https://openalex.org/W2008739372","https://openalex.org/W2009177556","https://openalex.org/W2010664010","https://openalex.org/W2010765832","https://openalex.org/W2011941985","https://openalex.org/W2013992160","https://openalex.org/W2017558624","https://openalex.org/W2019871639","https://openalex.org/W2020143693","https://openalex.org/W2020977183","https://openalex.org/W2023280641","https://openalex.org/W2023464568","https://openalex.org/W2023681059","https://openalex.org/W2025644609","https://openalex.org/W2025806545","https://openalex.org/W2028718056","https://openalex.org/W2030774611","https://openalex.org/W2031742858","https://openalex.org/W2032784244","https://openalex.org/W2033502671","https://openalex.org/W2034455408","https://openalex.org/W2038382492","https://openalex.org/W2039752037","https://openalex.org/W2039831781","https://openalex.org/W2042796303","https://openalex.org/W2044237823","https://openalex.org/W2045376133","https://openalex.org/W2046233805","https://openalex.org/W2048431959","https://openalex.org/W2048595403","https://openalex.org/W2049641275","https://openalex.org/W2049699863","https://openalex.org/W2050826158","https://openalex.org/W2053604249","https://openalex.org/W2055736359","https://openalex.org/W2058291016","https://openalex.org/W2058837262","https://openalex.org/W2058874815","https://openalex.org/W2058945984","https://openalex.org/W2060529943","https://openalex.org/W2061730652","https://openalex.org/W2063197497","https://openalex.org/W2064685463","https://openalex.org/W2066297166","https://openalex.org/W2066503688","https://openalex.org/W2068209156","https://openalex.org/W2068574233","https://openalex.org/W2069384378","https://openalex.org/W2069402089","https://openalex.org/W2070181692","https://openalex.org/W2073037575","https://openalex.org/W2075104388","https://openalex.org/W2075231192","https://openalex.org/W2078052745","https://openalex.org/W2079089334","https://openalex.org/W2080254032","https://openalex.org/W2081333853","https://openalex.org/W2081877072","https://openalex.org/W2081883639","https://openalex.org/W2083283628","https://openalex.org/W2086234351","https://openalex.org/W2089094328","https://openalex.org/W2092946228","https://openalex.org/W2094278935","https://openalex.org/W2095396894","https://openalex.org/W2096071880","https://openalex.org/W2097318458","https://openalex.org/W2098307144","https://openalex.org/W2098584567","https://openalex.org/W2098743205","https://openalex.org/W2099924309","https://openalex.org/W2101635391","https://openalex.org/W2103860290","https://openalex.org/W2104657012","https://openalex.org/W2106158410","https://openalex.org/W2107202876","https://openalex.org/W2109319750","https://openalex.org/W2111451129","https://openalex.org/W2111660568","https://openalex.org/W2112778345","https://openalex.org/W2114092300","https://openalex.org/W2114429616","https://openalex.org/W2114656311","https://openalex.org/W2114713121","https://openalex.org/W2114717670","https://openalex.org/W2115456836","https://openalex.org/W2115981201","https://openalex.org/W2116029803","https://openalex.org/W2116052538","https://openalex.org/W2121298241","https://openalex.org/W2123545797","https://openalex.org/W2125174015","https://openalex.org/W2127363947","https://openalex.org/W2127740849","https://openalex.org/W2127782460","https://openalex.org/W2127864943","https://openalex.org/W2132156834","https://openalex.org/W2133371501","https://openalex.org/W2133812567","https://openalex.org/W2134336290","https://openalex.org/W2134383199","https://openalex.org/W2134765924","https://openalex.org/W2136239752","https://openalex.org/W2136869363","https://openalex.org/W2139100680","https://openalex.org/W2142604626","https://openalex.org/W2143635839","https://openalex.org/W2144741700","https://openalex.org/W2146747402","https://openalex.org/W2146967348","https://openalex.org/W2150957352","https://openalex.org/W2152517124","https://openalex.org/W2159861873","https://openalex.org/W2163187326","https://openalex.org/W2164059021","https://openalex.org/W2166088416","https://openalex.org/W2168448139","https://openalex.org/W2169939207","https://openalex.org/W2172174356","https://openalex.org/W2308784387","https://openalex.org/W2497171922","https://openalex.org/W2523860607","https://openalex.org/W2802250175","https://openalex.org/W2953601685","https://openalex.org/W4243115481"],"related_works":["https://openalex.org/W1994665864","https://openalex.org/W2142440136","https://openalex.org/W7095640154","https://openalex.org/W2082746138","https://openalex.org/W2072091729","https://openalex.org/W2406087867","https://openalex.org/W2028718056","https://openalex.org/W4407056169","https://openalex.org/W2996750445","https://openalex.org/W2587216622"],"abstract_inverted_index":{"Women":[0],"over":[1,182,236,324,349],"the":[2,44,54,143,155,169,183,201,269,301,306,325,363,406,418,443,455,464,509,537],"age":[3,184,326],"of":[4,25,31,64,86,91,99,123,137,165,185,252,283,309,321,327,331,365,457,466,492],"80":[5,186],"represent":[6],"a":[7,104,107,160,449,462,501,522,550],"rapidly":[8],"growing":[9],"demographic":[10],"group.":[11],"While":[12],"older":[13,166,254,576],"women":[14,181,255,323,416],"live":[15],"longer":[16],"than":[17],"men,":[18],"they":[19],"do":[20],"so":[21],"with":[22,68,256,417,549,575],"more":[23,257,554],"years":[24,399],"disability":[26],"and":[27,40,51,75,83,131,157,210,235,244,268,311,360,367,394,402,413,427,435,476,483,521,541,557,569],"frailty.":[28,452,493,504],"The":[29,117,150,172,197,297,329,352,439,505,515],"emergence":[30],"geriatric":[32,567],"disorders":[33],"such":[34],"as":[35,339,358,374],"vascular":[36,126,270,446,486,498,527,544,579],"disease,":[37],"depression,":[38,359],"frailty":[39,130,458,467,532,555],"cognitive":[41,128,241,366,376,395,425,437],"decline":[42],"in":[43,142,168,175,231,294,318,336,362],"aging":[45,433],"US":[46],"population":[47],"place":[48],"additional":[49],"strain":[50],"expense":[52],"on":[53,239],"already":[55],"over-burdened":[56],"public":[57],"health":[58,80],"care":[59,65,81,88,565],"system.":[60],"Meanwhile,":[61],"integrated":[62,87,564],"models":[63],"are":[66,140,547],"associated":[67,548],"preserved":[69],"functional":[70],"independence,":[71],"reduced":[72],"medical":[73],"costs,":[74],"greater":[76,207,278],"satisfaction":[77],"for":[78,194,451,472,503,566,573],"both":[79],"providers":[82],"patients.":[84],"Implementation":[85],"demands":[89],"process-models":[90],"disease":[92],"that":[93,146,203,211,248,276,303,344,380,445,497,543],"contextualize":[94],"symptoms":[95,286,393,404,546,556],"within":[96],"broader":[97],"patterns":[98],"decline.":[100,377],"This":[101,190,561],"dissertation":[102,177],"proposes":[103],"model":[105,139,511,516],"representing":[106,305],"hypothesized":[108,118],"late-life":[109],"clinical":[110,551],"trajectory":[111,119,552],"following":[112],"from":[113,154,218,288,526],"high":[114,204,289],"cerebrovascular":[115],"burden.":[116],"includes":[120],"higher":[121],"rates":[122],"depression":[124,208,220,232,261,271,429,447,487,499,528,545,580],"(of":[125],"origin),":[127],"decline,":[129],"shortened":[132],"remaining":[133,559],"lifespan.":[134,560],"Different":[135],"facets":[136],"this":[138,148,176,319,337],"tested":[141,200,300,442,508],"four":[144],"studies":[145],"comprise":[147],"dissertation.":[149],"sample":[151,164,320],"was":[152,192,226,334,356,388,459,468,533],"drawn":[153],"Health":[156],"Retirement":[158],"Study;":[159],"longitudinal,":[161],"demographically-representative":[162],"data":[163],"adults":[167],"United":[170],"States.":[171],"sub-sample":[173,191],"used":[174,227],"included":[178],"1,368":[179],"stroke-free":[180,322],"at":[187,233,249,381,405,411],"baseline":[188,234],"(1998).":[189],"followed":[193],"10":[195],"years.":[196,351],"first":[198],"study":[199,299,441,507],"hypotheses":[202],"CVB":[205,340,401],"predicts":[206],"symptoms,":[209,430],"brain":[212,265],"reserve":[213,266],"(i.e.:":[214],"education)":[215],"protects":[216],"elders":[217],"developing":[219],"symptoms.":[221,262,581],"A":[222],"latent":[223],"growth":[224],"curve":[225],"to":[228,529],"identify":[229],"differences":[230],"time":[237],"based":[238],"CVB,":[240,253,290,391,423],"functioning,":[242,478],"education":[243,258,279],"age.":[245],"Results":[246,263,535],"indicate":[247],"any":[250],"level":[251],"experienced":[259],"fewer":[260],"support":[264,536],"theory":[267,434],"hypothesis.":[272],"These":[273,494],"results":[274],"suggest":[275,496,542],"having":[277],"may":[280],"postpone":[281],"development":[282],"clinically-significant":[284],"depressive":[285,392,403],"resulting":[287],"thereby":[291],"preserving":[292],"mood":[293],"late":[295],"life.":[296],"second":[298],"hypothesis":[302,444],"variables":[304],"three":[307],"domains":[308],"Rowe":[310],"Kahn's":[312],"Healthy":[313],"Aging":[314],"framework":[315,540],"predict":[316],"longevity":[317,420],"80.":[328],"\"avoidance":[330],"disease\"":[332],"domain":[333,371],"characterized":[335],"paper":[338],"-":[341],"chronic":[342],"comorbidites":[343],"slowly":[345],"erode":[346],"adaptive":[347],"functioning":[348,369,426],"many":[350],"\"sustained":[353],"engagement\"":[354],"criteria":[355],"conceptualized":[357],"deficits":[361],"\"preservation":[364],"physical":[368],"\"":[370],"were":[372],"identified":[373],"rapid":[375],"We":[378],"found":[379],"most":[382],"waves":[383],"(2002,":[384],"2004,":[385],"2006)":[386],"mortality":[387,410,530],"predicted":[389,409,489],"by":[390],"drop":[396],"measured":[397],"2":[398],"prior.":[400],"2000":[407],"wave":[408],"6":[412],"8-years.":[414],"Older":[415],"greatest":[419],"had":[421],"low":[422],"robust":[424],"few":[428],"supporting":[431],"successful":[432],"terminal":[436],"drop.":[438],"third":[440],"is":[448,500],"prodrome":[450,502],"At":[453],"baseline,":[454],"prevalence":[456],"31.5%.":[460],"Over":[461],"4-years":[463],"incidence":[465],"31.8%.":[469],"After":[470],"controlling":[471],"age,":[473],"education,":[474],"ADL":[475],"IADL":[477],"arthritis,":[479],"pulmonary":[480],"disorders,":[481],"cancer,":[482],"self-rated":[484],"health,":[485],"significantly":[488],"new":[490],"cases":[491],"findings":[495],"fourth":[506],"proposed":[510,538],"using":[512],"structural":[513],"modeling.":[514],"demonstrated":[517],"good":[518],"overall":[519],"fit":[520],"significant":[523],"indirect":[524],"pathway":[525],"through":[531],"identified.":[534],"theoretical":[539],"including":[553],"shorted":[558],"finding":[562],"supports":[563],"patients":[568,577],"suggests":[570],"specific":[571],"targets":[572],"intervention":[574],"experiencing":[578]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}
