{"id":"https://openalex.org/W120308753","doi":"https://doi.org/10.1055/s-0033-1335808","title":"S2k-Leitlinie Chronische Obstipation: Definition, Pathophysiologie, Diagnostik und Therapie","display_name":"S2k-Leitlinie Chronische Obstipation: Definition, Pathophysiologie, Diagnostik und Therapie","publication_year":2013,"publication_date":"2013-07-09","ids":{"openalex":"https://openalex.org/W120308753","doi":"https://doi.org/10.1055/s-0033-1335808","mag":"120308753","pmid":"https://pubmed.ncbi.nlm.nih.gov/23839919"},"language":"de","primary_location":{"id":"doi:10.1055/s-0033-1335808","doi":"https://doi.org/10.1055/s-0033-1335808","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0033-1335808","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0033-1335808.pdf","source":{"id":"https://openalex.org/S189922908","display_name":"Zeitschrift f\u00fcr Gastroenterologie","issn_l":"0044-2771","issn":["0044-2771","1439-7803"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Gastroenterologie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0033-1335808.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050602462","display_name":"Viola Andresen","orcid":"https://orcid.org/0000-0002-3695-3327","observed_orcids":["https://orcid.org/0000-0002-3695-3327"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"V. Andresen","raw_affiliation_strings":["Israelitisches Krankenhaus, Orchideenstieg 14, 22297 Hamburg. v.andresen@ik-h.de"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Israelitisches Krankenhaus, Orchideenstieg 14, 22297 Hamburg. v.andresen@ik-h.de","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073465749","display_name":"Paul Enck","orcid":"https://orcid.org/0000-0001-8873-0486","observed_orcids":["https://orcid.org/0000-0001-8873-0486"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P. Enck","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051385156","display_name":"Thomas Frieling","orcid":"https://orcid.org/0000-0001-8270-1975","observed_orcids":["https://orcid.org/0000-0001-8270-1975"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T. Frieling","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076772052","display_name":"A. Herold","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. Herold","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024860933","display_name":"P. Ilgenstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P. Ilgenstein","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056820764","display_name":"Nadine Jesse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"N. Jesse","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019203750","display_name":"Michael Karaus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Karaus","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Kasparek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Kasparek","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108426086","display_name":"J. Keller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J. Keller","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051418822","display_name":"Rita Kuhlbusch-Zicklam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R. Kuhlbusch-Zicklam","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112716493","display_name":"Heinz J. Krammer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Krammer","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038707461","display_name":"Martin Ernst Kreis","orcid":"https://orcid.org/0000-0002-9312-4840","observed_orcids":["https://orcid.org/0000-0002-9312-4840"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Kreis","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110030208","display_name":"Peter Layer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P. Layer","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009127419","display_name":"Ahmed Madisch","orcid":"https://orcid.org/0000-0001-9163-5893","observed_orcids":["https://orcid.org/0000-0001-9163-5893"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. Madisch","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022903373","display_name":"Harald Matthes","orcid":"https://orcid.org/0000-0002-4053-4379","observed_orcids":["https://orcid.org/0000-0002-4053-4379"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Matthes","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048354512","display_name":"Hubert M\u00f6nnikes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. M\u00f6nnikes","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114151751","display_name":"Stefan A M\u00fcller-Lissner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S. M\u00fcller-Lissner","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072233456","display_name":"J. Prei\u00df","orcid":"https://orcid.org/0000-0002-0901-1422","observed_orcids":["https://orcid.org/0000-0002-0901-1422"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J. Preiss","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Sailer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Sailer","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044612561","display_name":"Michael Schemann","orcid":"https://orcid.org/0000-0003-1007-9843","observed_orcids":["https://orcid.org/0000-0003-1007-9843","https://orcid.org/0009-0002-4069-2251"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Schemann","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031045352","display_name":"Juliane Schwille\u2010Kiuntke","orcid":"https://orcid.org/0000-0001-5224-4881","observed_orcids":["https://orcid.org/0000-0001-5224-4881"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J. Schwille-Kiuntke","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110355021","display_name":"W. A. Voderholzer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. Voderholzer","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063094129","display_name":"Ivo van der Voort","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"I. van der Voort","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014497378","display_name":"Thilo Wedel","orcid":"https://orcid.org/0000-0002-8146-2711","observed_orcids":["https://orcid.org/0000-0002-8146-2711"]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T. Wedel","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085842700","display_name":"Christian Pehl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138168","display_name":"Israelitisches Krankenhaus","ror":"https://ror.org/03r30hs79","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138168"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C. Pehl","raw_affiliation_strings":["Institut","Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut","institution_ids":[]},{"raw_affiliation_string":"Israelitisches Krankenhaus Orchideenstieg 14 22297 Hamburg","institution_ids":["https://openalex.org/I4210138168"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210138168"],"apc_list":null,"apc_paid":null,"fwci":4.3213,"has_fulltext":true,"cited_by_count":111,"citation_normalized_percentile":{"value":0.93827742,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"51","issue":"07","first_page":"651","last_page":"672"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10418","display_name":"Pelvic floor disorders treatments","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12089","display_name":"Intestinal and Peritoneal Adhesions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-constipation","display_name":"chronic constipation","score":0.9860000014305115},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.6959999799728394},{"id":"https://openalex.org/keywords/diagnosis","display_name":"diagnosis","score":0.7409999966621399},{"id":"https://openalex.org/keywords/treatment","display_name":"treatment","score":0.7179999947547913},{"id":"https://openalex.org/keywords/laxatives","display_name":"laxatives","score":0.5699999928474426},{"id":"https://openalex.org/keywords/self-medication","display_name":"self-medication","score":0.6489999890327454},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.7910000085830688},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome-with-constipation","display_name":"irritable bowel syndrome with constipation","score":0.5609999895095825},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":0.5849999785423279},{"id":"https://openalex.org/keywords/functional-gastrointestinal-disorders","display_name":"functional gastrointestinal disorders","score":0.4050000011920929},{"id":"https://openalex.org/keywords/lifestyle-modification","display_name":"lifestyle modification","score":0.3179999887943268},{"id":"https://openalex.org/keywords/patient-education","display_name":"patient education","score":0.3100000023841858},{"id":"https://openalex.org/keywords/role-of-pharmacists","display_name":"pharmacist role","score":0.4129999876022339},{"id":"https://openalex.org/keywords/quality-of-evidence","display_name":"quality of evidence","score":0.38199999928474426},{"id":"https://openalex.org/keywords/evidence-based-medicine","display_name":"evidence-based medicine","score":0.335999995470047}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6484309434890747},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4829122722148895}],"mesh":[{"descriptor_ui":"D003248","descriptor_name":"Constipation","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003248","descriptor_name":"Constipation","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003248","descriptor_name":"Constipation","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003938","descriptor_name":"Diagnostic Techniques, Digestive System","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D004043","descriptor_name":"Dietary Fiber","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005762","descriptor_name":"Gastroenterology","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D005765","descriptor_name":"Gastrointestinal Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005858","descriptor_name":"Germany","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1055/s-0033-1335808","doi":"https://doi.org/10.1055/s-0033-1335808","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0033-1335808","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0033-1335808.pdf","source":{"id":"https://openalex.org/S189922908","display_name":"Zeitschrift f\u00fcr Gastroenterologie","issn_l":"0044-2771","issn":["0044-2771","1439-7803"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Gastroenterologie","raw_type":"journal-article"},{"id":"pmid:23839919","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23839919","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift fur Gastroenterologie","raw_type":"Journal Article"},{"id":"mag:2589870664","doi":null,"is_oa":false,"landing_page_url":"https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0033-1335808.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1055/s-0033-1335808","doi":"https://doi.org/10.1055/s-0033-1335808","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0033-1335808","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0033-1335808.pdf","source":{"id":"https://openalex.org/S189922908","display_name":"Zeitschrift f\u00fcr Gastroenterologie","issn_l":"0044-2771","issn":["0044-2771","1439-7803"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Gastroenterologie","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W120308753.pdf","grobid_xml":"https://content.openalex.org/works/W120308753.grobid-xml"},"referenced_works_count":253,"referenced_works":["https://openalex.org/W4090007","https://openalex.org/W17847393","https://openalex.org/W85117232","https://openalex.org/W86276696","https://openalex.org/W87452291","https://openalex.org/W98359721","https://openalex.org/W120282241","https://openalex.org/W123269161","https://openalex.org/W132779679","https://openalex.org/W167458392","https://openalex.org/W172476541","https://openalex.org/W178941457","https://openalex.org/W196318749","https://openalex.org/W1481988434","https://openalex.org/W1486462492","https://openalex.org/W1488117727","https://openalex.org/W1490141590","https://openalex.org/W1491518420","https://openalex.org/W1504237202","https://openalex.org/W1511281268","https://openalex.org/W1515885878","https://openalex.org/W1516221174","https://openalex.org/W1521005513","https://openalex.org/W1534087234","https://openalex.org/W1536522020","https://openalex.org/W1552656977","https://openalex.org/W1553759809","https://openalex.org/W1570847228","https://openalex.org/W1573236912","https://openalex.org/W1582795936","https://openalex.org/W1584102271","https://openalex.org/W1586344864","https://openalex.org/W1601202529","https://openalex.org/W1921373566","https://openalex.org/W1959276090","https://openalex.org/W1965150381","https://openalex.org/W1965170794","https://openalex.org/W1965194352","https://openalex.org/W1967424343","https://openalex.org/W1967426171","https://openalex.org/W1968228152","https://openalex.org/W1968285023","https://openalex.org/W1968380796","https://openalex.org/W1969468715","https://openalex.org/W1970590822","https://openalex.org/W1973915683","https://openalex.org/W1973982536","https://openalex.org/W1974193786","https://openalex.org/W1974376797","https://openalex.org/W1975167841","https://openalex.org/W1975667650","https://openalex.org/W1976200263","https://openalex.org/W1976656065","https://openalex.org/W1979432045","https://openalex.org/W1979880202","https://openalex.org/W1981316817","https://openalex.org/W1981867849","https://openalex.org/W1983889266","https://openalex.org/W1984819815","https://openalex.org/W1985472116","https://openalex.org/W1986027267","https://openalex.org/W1987172422","https://openalex.org/W1988480237","https://openalex.org/W1988861021","https://openalex.org/W1989076609","https://openalex.org/W1989721370","https://openalex.org/W1991496489","https://openalex.org/W1991782395","https://openalex.org/W1992857911","https://openalex.org/W1992935856","https://openalex.org/W1993226188","https://openalex.org/W1993910923","https://openalex.org/W1995870777","https://openalex.org/W1997800332","https://openalex.org/W1999580880","https://openalex.org/W2002414046","https://openalex.org/W2004063103","https://openalex.org/W2005068072","https://openalex.org/W2007024901","https://openalex.org/W2007109458","https://openalex.org/W2008876886","https://openalex.org/W2009711584","https://openalex.org/W2011057837","https://openalex.org/W2011067498","https://openalex.org/W2011814583","https://openalex.org/W2012079990","https://openalex.org/W2012236727","https://openalex.org/W2012990071","https://openalex.org/W2014557782","https://openalex.org/W2014563956","https://openalex.org/W2016199303","https://openalex.org/W2017662558","https://openalex.org/W2018154855","https://openalex.org/W2018828467","https://openalex.org/W2019015071","https://openalex.org/W2019181558","https://openalex.org/W2019556071","https://openalex.org/W2020188527","https://openalex.org/W2020607350","https://openalex.org/W2021644665","https://openalex.org/W2022599897","https://openalex.org/W2022852462","https://openalex.org/W2022999398","https://openalex.org/W2023242215","https://openalex.org/W2024449898","https://openalex.org/W2025409221","https://openalex.org/W2026468855","https://openalex.org/W2027670376","https://openalex.org/W2032300996","https://openalex.org/W2032762072","https://openalex.org/W2035100254","https://openalex.org/W2037410387","https://openalex.org/W2039297899","https://openalex.org/W2041423290","https://openalex.org/W2041581988","https://openalex.org/W2041631242","https://openalex.org/W2042615016","https://openalex.org/W2045441077","https://openalex.org/W2045854219","https://openalex.org/W2046201279","https://openalex.org/W2046572579","https://openalex.org/W2046843788","https://openalex.org/W2047467575","https://openalex.org/W2047613598","https://openalex.org/W2047714868","https://openalex.org/W2049021534","https://openalex.org/W2049063453","https://openalex.org/W2050474370","https://openalex.org/W2050769859","https://openalex.org/W2051720609","https://openalex.org/W2051741199","https://openalex.org/W2052825160","https://openalex.org/W2053616856","https://openalex.org/W2053773667","https://openalex.org/W2055062901","https://openalex.org/W2056042238","https://openalex.org/W2057419362","https://openalex.org/W2057616255","https://openalex.org/W2060478811","https://openalex.org/W2061136386","https://openalex.org/W2061212461","https://openalex.org/W2061983344","https://openalex.org/W2062164727","https://openalex.org/W2063621782","https://openalex.org/W2064017014","https://openalex.org/W2064137248","https://openalex.org/W2064201279","https://openalex.org/W2065061684","https://openalex.org/W2066242844","https://openalex.org/W2068454300","https://openalex.org/W2070556044","https://openalex.org/W2071102937","https://openalex.org/W2075060035","https://openalex.org/W2075171137","https://openalex.org/W2075825545","https://openalex.org/W2075901099","https://openalex.org/W2076235879","https://openalex.org/W2076373003","https://openalex.org/W2077138162","https://openalex.org/W2077540878","https://openalex.org/W2078248922","https://openalex.org/W2079448135","https://openalex.org/W2079545941","https://openalex.org/W2082111966","https://openalex.org/W2082390684","https://openalex.org/W2084196341","https://openalex.org/W2085025198","https://openalex.org/W2085412181","https://openalex.org/W2087233808","https://openalex.org/W2088344246","https://openalex.org/W2089092750","https://openalex.org/W2089667582","https://openalex.org/W2090144284","https://openalex.org/W2091067422","https://openalex.org/W2092547603","https://openalex.org/W2092969298","https://openalex.org/W2093710588","https://openalex.org/W2095211103","https://openalex.org/W2095271340","https://openalex.org/W2095464607","https://openalex.org/W2097844643","https://openalex.org/W2098064583","https://openalex.org/W2106952837","https://openalex.org/W2108007239","https://openalex.org/W2109576127","https://openalex.org/W2113067487","https://openalex.org/W2117853594","https://openalex.org/W2118790021","https://openalex.org/W2119541654","https://openalex.org/W2121519021","https://openalex.org/W2125611641","https://openalex.org/W2126464556","https://openalex.org/W2130413157","https://openalex.org/W2132145612","https://openalex.org/W2132379521","https://openalex.org/W2132419648","https://openalex.org/W2136157744","https://openalex.org/W2138857851","https://openalex.org/W2139696857","https://openalex.org/W2146057131","https://openalex.org/W2148439671","https://openalex.org/W2148613124","https://openalex.org/W2150055664","https://openalex.org/W2152594924","https://openalex.org/W2154491858","https://openalex.org/W2158281754","https://openalex.org/W2161364374","https://openalex.org/W2161575163","https://openalex.org/W2162478283","https://openalex.org/W2162836422","https://openalex.org/W2164341191","https://openalex.org/W2166167540","https://openalex.org/W2166563630","https://openalex.org/W2167159877","https://openalex.org/W2168967776","https://openalex.org/W2169063511","https://openalex.org/W2170633974","https://openalex.org/W2170665307","https://openalex.org/W2171477352","https://openalex.org/W2188133065","https://openalex.org/W2228576357","https://openalex.org/W2266799291","https://openalex.org/W2322540686","https://openalex.org/W2326231927","https://openalex.org/W2333952961","https://openalex.org/W2363736511","https://openalex.org/W2397187023","https://openalex.org/W2403598178","https://openalex.org/W2407164291","https://openalex.org/W2410950947","https://openalex.org/W2411451060","https://openalex.org/W2411882168","https://openalex.org/W2412825140","https://openalex.org/W2412998126","https://openalex.org/W2414562981","https://openalex.org/W2414685123","https://openalex.org/W2419108533","https://openalex.org/W2426716448","https://openalex.org/W2443067216","https://openalex.org/W2464604880","https://openalex.org/W2496999344","https://openalex.org/W2792876819","https://openalex.org/W3025714204","https://openalex.org/W4230073929","https://openalex.org/W4232048077","https://openalex.org/W4234376416","https://openalex.org/W4236621864","https://openalex.org/W4240958664","https://openalex.org/W4241495333","https://openalex.org/W4242976592","https://openalex.org/W4243088983","https://openalex.org/W4248995128","https://openalex.org/W4249342203"],"related_works":["https://openalex.org/W2317123836","https://openalex.org/W4304807329","https://openalex.org/W3134748098","https://openalex.org/W4281486778","https://openalex.org/W2056743031","https://openalex.org/W1983127040","https://openalex.org/W4367595890","https://openalex.org/W4400085405","https://openalex.org/W4367154644","https://openalex.org/W2009847360"],"abstract_inverted_index":{"Einleitung":[0,727],"und":[1,29,50,82,104,147,174,188,293,320,337,397,495,514,532,581,586,597,608,636,639,645,651,670,728,741,755,764,774,781,789,863,876,879,885,892,913,933,949,996,1021,1056,1074,1078,1130,1144,1257,1331,1346,1361,1378,1392,1412,1423,1438,1472,1519,1605,1682],"Methodik":[2,555,561,729],"E-1":[3,731],"Hintergrund":[4,732],"Chronische":[5],"Obstipationsbeschwerden":[6],"z\u00e4hlen":[7],"mit":[8,25,259,654,943,1457,1489,1536,1665],"einer":[9,98,378,410,480,1070,1458,1633],"Pr\u00e4valenz":[10,24],"von":[11,100,219,276,283,629,749,1038,1045,1099,1353,1409,1558,1566,1577,1588,1599],"5":[12,551,957,1182],"\u2013":[13,110,114,1569,1580],"15":[14],"%":[15,1561,1571,1582,1592],"zu":[16,86,288,316,335,405,443,566,578,719],"den":[17,313,395,444,478,1000,1039,1111,1338,1478],"h\u00e4ufigen":[18],"Gesundheitsst\u00f6rungen":[19],"in":[20,107,166,177,249,373,426,435,440,516,519,1029,1085,1110,1117,1384,1524,1547,1632],"Deutschland,":[21],"wobei":[22],"die":[23,60,94,126,134,167,178,358,364,388,458,466,510,524,543,563,593,640,661,672,700,701,714,952,980,999,1061,1081,1450,1454,1497,1502,1534,1651],"dem":[26,572],"Alter":[27],"zunimmt":[28],"Frauen":[30],"deutlich":[31,113],"h\u00e4ufiger":[32],"betroffen":[33],"sind":[34,47,116,571,1109,1116,1470,1483,1523,1631],"als":[35,131,399,421,430,968,1590],"M\u00e4nner":[36],"[":[37,40,117,120,550,956,1118,1525],"1":[38,1128,1261,1310,1662],"]":[39,119,552,1262,1528],"2":[41,1142],"].":[42,122,958],"Die":[43,55,419,449,502,588,631,681,938,959,973,985,1024,1052,1114,1517,1595,1625],"zugrunde":[44,1539],"liegenden":[45,1540],"Pathomechanismen":[46],"komplex,":[48],"uneinheitlich":[49],"nur":[51,129],"z.":[52,111],"T.":[53,112,1149,1155],"aufgekl\u00e4rt.":[54],"verf\u00fcgbare":[56],"Evidenz":[57,237,331],"hat":[58,940],"aber":[59,437],"traditionelle":[61],"Auffassung":[62,206],"widerlegt,":[63],"dass":[64,93,145,242,357],"es":[65,243],"sich":[66,244,390,453,506,599,1646],"lediglich":[67,160],"um":[68,254],"eine":[69,255,361,469,497,722,1037,1498],"banale":[70],"Befindlichkeitsst\u00f6rung":[71],"ohne":[72],"Krankheitswert":[73],"handele,":[74],"welche":[75,275],"\u00fcberdies":[76],"durch":[77,979,994,1365,1434,1449,1513],"falsche":[78],"Lebensgewohnheiten":[79],"selbst":[80],"verschuldet":[81],"daher":[83,189,391,429],"auch":[84,142,214,239,351,392,522],"leicht":[85],"korrigieren":[87],"sei.":[88],"So":[89],"wurde":[90,692,992,1044,1067,1097,1597],"\u00fcberzeugend":[91],"belegt,":[92],"Betroffenen":[95],"dabei":[96,454,496,686,713,1612,1647],"unter":[97,161,1635],"Vielzahl":[99],"bel\u00e4stigenden":[101],"Symptomen":[102],"leiden":[103],"sie":[105,213],"dadurch":[106,143],"ihrer":[108,221],"Lebensqualit\u00e4t":[109],"beeintr\u00e4chtigt":[115],"3":[118,1030,1153,1410],"4":[121,1166],"Dessen":[123],"ungeachtet":[124],"wird":[125,141,193,537],"chronische":[127,359],"Obstipation":[128,248,270,324,360,525,976,1455],"unzureichend":[130],"ein":[132,366,669,717,1514],"f\u00fcr":[133,154,207,465,523,592,634,643,699,883,890,899,905,911,918,947,970,1080,1603,1668,1674,1680,1687],"Patienten":[135],"oft":[136,398],"relevantes":[137],"Gesundheitsproblem":[138],"akzeptiert.":[139],"Dies":[140],"deutlich,":[144],"etablierte":[146],"effektive":[148],"medikament\u00f6se":[149,432,816,828,1186,1204],"Therapieans\u00e4tze,":[150],"deren":[151],"regelm\u00e4\u00dfige":[152],"Einnahme":[153],"schwerer":[155],"Betroffene":[156],"meist":[157,209],"unverzichtbar":[158],"ist,":[159,363],"der":[162,169,180,196,246,250,252,267,269,304,307,322,329,352,374,376,409,414,461,472,486,498,512,560,569,576,604,606,626,655,657,674,683,736,746,772,908,944,962,1019,1026,1046,1054,1086,1100,1125,1246,1318,1325,1350,1363,1375,1396,1414,1421,1426,1436,1490,1504,1507,1511,1521,1537,1562,1572,1583,1593,1600,1616,1622,1628,1643,1650,1653,1677],"undefinierten":[163,396],"Etikettierung":[164],"\u201eLaxans\u201c":[165,404],"Sparte":[168],"nicht":[170,257,439,1550],"verschreibungsf\u00e4higen":[171],"Selbstmedikation":[172],"verbannt":[173],"quasi":[175],"allein":[176,194],"H\u00e4nde":[179],"Apotheker":[181],"\u00fcbergeben":[182],"worden":[183],"sind.":[184],"Selbst":[185],"neueren,":[186],"innovativen":[187],"noch":[190,1398],"verschreibungspflichtigen":[191],"Medikamenten":[192],"aufgrund":[195],"Indikation":[197],"\u201eObstipation\u201c":[198],"ihre":[199],"allgemeine":[200],"Erstattungsf\u00e4higkeit":[201],"genommen.":[202],"Tats\u00e4chlich":[203],"mag":[204],"diese":[205,971],"milde,":[208],"transiente":[210],"Obstipationsbeschwerden,":[211],"wie":[212,238,620],"viele":[215],"Gesunde":[216],"im":[217,281,333,455,960,986,1068],"Rahmen":[218,479,518,961,1069],"\u00c4nderungen":[220],"Lebensumst\u00e4nde":[222],"(z.":[223],"B.":[224],"Reisen,":[225],"fremdl\u00e4ndische":[226],"Kost":[227],"o.":[228],"\u00c4.)":[229],"erleben,":[230],"angemessen":[231],"sein.":[232,984],"Demgegen\u00fcber":[233],"untermauern":[234],"sowohl":[235],"wissenschaftliche":[236],"medizinische":[240,595],"Realit\u00e4t,":[241],"bei":[245,325,1337],"chronischen":[247,323,462],"Mehrzahl":[251,375],"F\u00e4lle":[253,377],"persistierende,":[256],"selten":[258],"hohem":[260],"Leidensdruck":[261],"einhergehende":[262],"Erkrankung":[263,362,411],"handelt.":[264],"Dabei":[265],"kann":[266],"Symptomkomplex":[268],"ganz":[271],"unterschiedliche":[272],"Ursachen":[273],"haben,":[274],"unerw\u00fcnschten":[277],"Arzneimittelwirkungen":[278,1486],"\u00fcber":[279],"Stoffwechselst\u00f6rungen":[280],"Sinne":[282,296],"sekund\u00e4ren":[284,467],"Obstipationsformen":[285,468,488],"bis":[286,1320,1356,1370,1387,1405,1417,1428,1445],"hin":[287],"Erkrankungen":[289],"des":[290,403,663,1432,1440,1638],"enterischen":[291],"Nerven-":[292],"Muskelsystems":[294],"(im":[295],"prim\u00e4rer":[297],"Obstipationsformen)":[298],"reichen":[299],"k\u00f6nnen.":[300,1658],"#":[301,554,623,872,895,926,927,1016,1659,1660,1661],"E-2":[302,734],"Ziele":[303,735],"Leitlinie":[305,349,428,482,577,702,737,1416,1427,1596,1654],"Ziel":[306],"vorliegenden":[308,503],"interdisziplin\u00e4ren":[309],"S2k-Leitlinie":[310,1549],"war":[311,724],"es,":[312],"aktuellen":[314],"Kenntnisstand":[315],"Definition,":[317],"Pathophysiologie,":[318],"Diagnostik":[319,607,796,1154],"Therapie":[321,381,416,609,802,813,817,825,835,838,844,852,860,1167,1183,1187,1201,1223,1226,1238,1251,1254,1482],"Erwachsenen":[326],"auf":[327,457,509,542],"Basis":[328,969],"wissenschaftlichen":[330],"zusammenzufassen,":[332],"Experten-Konsens":[334],"bewerten":[336],"daraus":[338],"praxisrelevante":[339],"Empfehlungen":[340,504,589,773,805,1020,1027,1170,1535,1652],"abzuleiten.":[341],"Hierzu":[342],"seien":[343],"einige":[344],"erl\u00e4uternde":[345],"Vorbemerkungen":[346],"vorausgeschickt:":[347],"Diese":[348,659],"soll":[350],"allgemeinen":[353],"Aufkl\u00e4rung":[354],"dar\u00fcber":[355],"dienen,":[356],"grunds\u00e4tzlich":[365],"gewisses":[367],"Ma\u00df":[368],"an":[369,539,600,605,621,1060],"diagnostischer":[370],"Abkl\u00e4rung":[371],"sowie":[372,562,1509],"dauerhaften":[379],"medikament\u00f6sen":[380,415,1481],"zugef\u00fchrt":[382],"werden":[383,425,1089],"muss.":[384],"Ganz":[385],"bewusst":[386,438],"setzen":[387],"Leitlinienautoren":[389,570],"daf\u00fcr":[393],"ein,":[394],"negativ":[400],"empfundenen":[401],"Begriff":[402,413],"verlassen.":[406],"Vielmehr":[407],"sollte":[408,977],"angemessene":[412],"bevorzugt":[417],"werden.":[418],"bisher":[420],"\u201eLaxanzien\u201c":[422],"bekannten":[423],"Behandlungsformen":[424],"dieser":[427,540,1095,1548],"konventionelle":[431],"Therapieans\u00e4tze":[433,829,1205],"bezeichnet":[434],"historischer,":[436],"formaler":[441],"Abgrenzung":[442],"modernen":[445],"Arzneimittel-Entwicklungen":[446],"zur":[447,975,1480],"Obstipationsbehandlung.":[448],"erl\u00e4uterten":[450],"Therapiekonzepte":[451],"beschr\u00e4nken":[452],"Wesentlichen":[456],"prim\u00e4ren":[459,487],"Formen":[460],"Obstipation,":[463],"da":[464],"umfassende":[470,546],"Darlegung":[471],"therapeutischen":[473],"Optionen":[474],"aller":[475,520,1403],"m\u00f6glichen":[476],"Grundkrankheiten/-st\u00f6rungen":[477],"evidenzbasierten":[481],"\u00fcbersteigen":[483],"w\u00fcrde.":[484],"Innerhalb":[485],"stellt":[489],"das":[490,601],"obstipationspr\u00e4dominante":[491],"Reizdarmsyndrom":[492,527,536,549,954,989],"einen":[493,706],"Sonderfall":[494],"wichtigsten":[499],"Untergruppen":[500],"dar.":[501],"richten":[505,598],"jedoch":[507,538,1014,1464],"prim\u00e4r":[508,687],"Behandlung":[511],"Obstipationssymptome":[513],"haben":[515],"diesem":[517],"Regel":[521],"beim":[526],"G\u00fcltigkeit.":[528],"F\u00fcr":[529],"umfassendere":[530],"Informationen":[531],"Therapieempfehlungen":[533],"zum":[534,548,806,1171],"polysymptomatischen":[535],"Stelle":[541],"k\u00fcrzlich":[544],"publizierte":[545],"S3-Leitlinie":[547,953],"verwiesen.":[553],"Hinweis:":[556],"Eine":[557,1009,1064,1608],"ausf\u00fchrliche":[558],"Beschreibung":[559],"detaillierten":[564],"Angaben":[565],"potenziellen":[567],"Interessenkonflikten":[568],"separat":[573],"ver\u00f6ffentlichten":[574],"Methodik-Report":[575],"entnehmen":[579],"(Preiss":[580],"Andresen,":[582,1207,1295],"AWMF).":[583],"M-1":[584,679,739,1123],"Versorgungsbereich":[585,740],"Zielgruppen":[587,742],"gelten":[590,703],"insbesondere":[591],"ambulante":[594],"Versorgung":[596],"gesamte":[602],"Spektrum":[603],"beteiligten":[610,710,1451],"Berufsgruppen":[611],"(Allgemeinmediziner,":[612],"Internisten,":[613],"Gastroenterologen,":[614],"Proktologen,":[615],"Chirurgen,":[616],"Psychologen,":[617],"Psychosomatiker)":[618],"ebenso":[619],"Betroffene.":[622],"M-2":[624,744,1034,1316],"Zusammensetzung":[625,745],"Leitliniengruppe:":[627,747],"Beteiligung":[628,748],"Interessengruppen":[630,750],"Deutsche":[632,641,881,888,897,916,921,1666,1685,1690],"Gesellschaft":[633,642,882,889,898,910,917,946,1602,1667,1679,1686],"Neurogastroenterologie":[635,884,1604],"Motilit\u00e4t":[637,886,1606],"(DGNM)":[638,887,1137],"Verdauungs-":[644,891,948],"Stoffwechselkrankheiten":[646,893,950],"(DGVS)":[647,894,951,1161],"beauftragten":[648],"Viola":[649],"Andresen":[650],"Christian":[652],"Pehl":[653],"Koordination":[656,880,1293],"Leitlinie.":[658,972,1126,1319],"legten":[660],"Eckpunkte":[662],"Konsentierungsverfahrens":[664],"fest,":[665],"luden":[666],"andere":[667],"Fachgesellschaften":[668,711,756,877,1341,1452],"w\u00e4hlten":[671],"Mitglieder":[673,1615],"Arbeitsgruppen":[675,1040,1062],"aus":[676,696],"([":[677,1032],"Tab.":[678,1033,1119,1122,1315,1526,1552],"]).":[680,1035],"Auswahl":[682,763,932],"AG-Mitglieder":[684],"erfolgte":[685,1013,1028,1611],"nach":[688,1395],"fachlicher":[689],"Expertise.":[690],"Es":[691],"Wert":[693],"darauf":[694],"gelegt,":[695],"jeder":[697],"Berufsgruppe,":[698],"soll,":[704],"mindestens":[705,716],"Vertreter":[707],"miteinzubeziehen.":[708],"Alle":[709,1614],"hatten":[712],"M\u00f6glichkeit,":[715],"AG-Mitglied":[718],"benennen.":[720],"Auch":[721],"Patientenvertreterin":[723],"beteiligt.":[725],"Inhaltsverzeichnis":[726],"651":[730,733],"652":[738,743,751],"M-3":[752,873,1120,1553],"Beteiligte":[753,874],"Gruppierungen":[754,875],"653":[757,760,769,777],"M-4":[758,928,1527],"Durchf\u00fchrung":[759,929],"a)":[761,930],"Recherche,":[762,931],"Bewertung":[765,934],"wissenschaftlicher":[766,935],"Belege":[767,936],"(Evidenzbasierung)":[768,937],"b)":[770,1017],"Formulierung":[771,1018,1508],"strukturierte":[775,1022],"Konsensfindung":[776,1023],"Kapitel":[778,786,794,800,811,823,833,842,850,858,987],"1:":[779],"Definition":[780,1129],"Epidemiologie":[782,1131],"(AG":[783,791,797,808,820,830,839,847,855,867],"1)":[784],"654":[785],"2:":[787],"\u00c4tiologie":[788,1143],"Pathophysiologie":[790,1145],"2)":[792,1344],"655":[793],"3:":[795],"3)":[798],"657":[799],"4:":[801],"A:":[803,1168],"Allgemeine":[804,1169],"Therapie-Management":[807,1172],"4)":[809],"658":[810],"5:":[812],"B:":[814,1184],"Konventionelle":[815,1185],"(konventionelle":[818,1188],"\u201eLaxanzien\u201c)":[819,1189],"5)":[821],"660":[822],"6:":[824],"C:":[826,1202],"Neue":[827,1203],"6)":[831],"662":[832],"7:":[834],"D:":[836,1224],"Chirurgische":[837,903,1225,1672],"7)":[840],"663":[841],"8:":[843],"E:":[845,1239],"Biofeedback":[846,1240],"8)":[848],"665":[849],"9:":[851],"F:":[853,1252],"Probiotika":[854,1253],"9)":[856,868],"666":[857,869],"10:":[859],"G:":[861,1255],"Komplement\u00e4re":[862,1256],"alternativmedizinische":[864,1258],"Methoden":[865,1259],"(CAM)":[866],"Literatur":[870,974,991,1437,1541],"667":[871],"Federf\u00fchrung":[878],"Mitarbeit":[896],"Innere":[900,1669],"Medizin":[901,1670],"(DGIM)":[902],"Arbeitsgemeinschaft":[904,1673],"Coloproktologie":[906,1675],"(CACP)":[907,1676],"Deutschen":[909,945,1601,1678],"Allgemein-":[912,1681],"Viszeralchirurgie":[914,1683],"(DGAV)":[915],"Koloproktologie":[919,1688],"(DGK)":[920,1266],"Reizdarmselbsthilfe":[922,1275,1691],"e.":[923,1276,1692],"V.":[924,1206,1294,1693],"(Patientenorganisation)":[925,1694],"DGNM":[939],"2011":[941,1323,1348,1359,1373,1381,1389],"gemeinsam":[942,1488],"herausgegeben":[955],"dort":[963],"durchgef\u00fchrten":[964],"systematischen":[965],"Literatursuche":[966,1012],"diente":[967],"weitgehend":[978],"verwendete":[981],"Suchstrategie":[982],"abgedeckt":[983],"obstipationsbetontes":[988],"ausgew\u00e4hlte":[990],"erg\u00e4nzt":[993],"weitere":[995],"neuere":[997],"Arbeiten,":[998],"Arbeitsgruppenmitgliedern":[1001],"bekannt":[1002],"waren":[1003],"oder":[1004,1107,1544],"individuell":[1005],"neu":[1006],"recherchiert":[1007],"wurden.":[1008],"erneute":[1010,1390],"systematische":[1011],"nicht.":[1015,1613],"Konsentierung":[1025],"Phasen":[1031],"\u00dcber":[1036],"erstellte":[1041],"erste":[1042],"Version":[1043,1066],"gesamten":[1047],"Konsensgruppe":[1048],"per":[1049,1102,1367],"E-Mail":[1050,1103,1368],"abgestimmt.":[1051,1104],"Ergebnisse":[1053],"Abstimmung":[1055,1420],"obligatorische":[1057],"Kommentare":[1058,1404],"wurden":[1059,1091,1533,1546],"zur\u00fcckgespiegelt.":[1063],"zweite":[1065],"2-t\u00e4gigen":[1071],"Konsensuskonferenz":[1072,1383],"diskutiert":[1073],"bearbeitet.":[1075],"Einige":[1076],"Statements":[1077,1351,1376],"Empfehlungen,":[1079],"kein":[1082,1585,1648],"ausreichender":[1083],"Konsens":[1084,1556,1564,1586],"Plenarsitzung":[1087],"erreicht":[1088],"konnte,":[1090],"erneut":[1092,1098],"\u00fcberarbeitet.":[1093],"In":[1094,1477,1530,1663],"Phase":[1096],"Konsensusgruppe":[1101,1617],"Persistierender":[1105],"Dissens":[1106],"Minderheitenmeinungen":[1108],"Kommentaren":[1112,1355,1532],"diskutiert.":[1113,1493],"Konsensst\u00e4rken":[1115],"]dargestellt.":[1121],"Mitarbeiter":[1124],"AG":[1127,1141,1152,1165,1181,1199,1221,1236,1249],"Prof.":[1132],"Dr.":[1133],"P.":[1134,1216,1271],"Enck,":[1135],"T\u00fcbingen":[1136,1140],"J.":[1138,1158,1280,1312],"Schwille-Kiuntke,":[1139],"M.":[1146,1178,1227,1230,1290],"Schemann,":[1147],"M\u00fcnchen":[1148,1229],"Wedel,":[1150],"Kiel":[1151],"Frieling,":[1156],"Krefeld":[1157,1164],"Keller,":[1159],"Hamburg":[1160,1208,1214,1218,1296,1309],"R.":[1162],"Kuhlbusch-Zicklam,":[1163],"C.":[1173,1281,1300],"Pehl,":[1174,1301],"Vilsbiburg":[1175,1302],"(DGNM,":[1176,1209,1297,1303],"DGVS)":[1177,1304],"Karaus,":[1179],"G\u00f6ttingen":[1180],"A.":[1190,1286],"Madisch,":[1191],"Hannover":[1192],"S.":[1193],"M\u00fcller-Lissner,":[1194],"Berlin":[1195,1198,1233,1243,1248,1269,1283],"W.":[1196],"Voderholzer,":[1197],"6":[1200],"DGVS,":[1210,1298],"DGIM)":[1211,1220,1299],"N.":[1212],"Jesse,":[1213],"(Allgemeinmedizin)":[1215],"Layer,":[1217],"(DGVS,":[1219],"7":[1222],"Kasparek,":[1228],"E.":[1231],"Kreis,":[1232],"(DGAV,":[1234],"DGK)":[1235],"8":[1237],"H.":[1241,1263,1267],"M\u00f6nnikes,":[1242],"I.":[1244],"van":[1245],"Voort,":[1247],"9":[1250,1637],"(CAM)[":[1260],"Krammer,":[1264],"Mannheim":[1265,1288],"Matthes,":[1268],"Patientenvertreter":[1270],"Ilgenstein,":[1272],"Burgdorf":[1273],"(Deutsche":[1274],"V.)":[1277],"methodische":[1278],"Beratung":[1279,1285],"Prei\u00df,":[1282],"inhaltliche":[1284,1609],"Herold,":[1287],"(CACP-DGAV)":[1289,1292],"Sailer":[1291],"redaktionelle":[1305],"Unterst\u00fctzung":[1306],"D.":[1307],"Menge,":[1308],"Beratung:":[1311],"Langhorst,":[1313],"Essen.":[1314],"Zeitplan":[1317],"Ende":[1321,1357],"Mai":[1322],"Zusammenstellung":[1324],"Gruppen:":[1326],"Auswahl,":[1327],"Anfragen":[1328],"Zu-/Absagen":[1329],"(Gruppen":[1330],"Teilnehmer":[1332,1563,1573,1584,1594],"siehe":[1333],"Punkt":[1334,1343,1636],"3)+":[1335],"Anfrage":[1336],"anderen":[1339],"unterst\u00fctzenden":[1340],"(siehe":[1342],"Juni":[1345,1418],"Juli":[1347],"Entwurf":[1349],"UND":[1352],"begleitenden":[1354],"August":[1358],"Sichtung":[1360],"Kommentierung":[1362],"Entw\u00fcrfe":[1364],"alle":[1366],"(Delphi)":[1369],"Mitte":[1371],"September":[1372,1380],"\u00dcberarbeitung":[1374,1391],"14.":[1377],"17.":[1379],"2-t\u00e4gige":[1382],"Leipzig":[1385],"Oktober":[1386],"Dezember":[1388],"E-Mail-Abstimmung":[1393],"einiger":[1394],"KK":[1397],"offenen":[1399],"Statements;":[1400],"au\u00dferdem":[1401],"Fertigstellung":[1402,1413,1431],"M\u00e4rz":[1406],"2012":[1407,1419,1430],"Erg\u00e4nzung":[1408,1439],"CAM-Statements":[1411,1422],"\u00fcbrigen":[1415],"finale":[1424],"Freigabe":[1425],"November":[1429],"Manuskripts":[1433],"Einarbeitung":[1435],"Methodikteils":[1441],"+":[1442],"separaten":[1443],"Methodik-Reports":[1444],"Februar":[1446],"2013":[1447],"Begutachtung":[1448],"Da":[1453],"zwar":[1456],"deutlichen":[1459],"Lebensqualit\u00e4tseinbu\u00dfe":[1460],"verbunden":[1461],"sein":[1462],"kann,":[1463],"\u00fcblicherweise":[1465],"keine":[1466],"erh\u00f6hte":[1467],"Mortalit\u00e4t":[1468],"hat,":[1469],"Nutzen":[1471],"Risiken":[1473],"besonders":[1474],"vorsichtig":[1475],"abzuw\u00e4gen.":[1476],"Kapiteln":[1479],"potenzielle":[1484,1619],"unerw\u00fcnschte":[1485],"jeweils":[1487,1538],"erwarteten":[1491],"Wirkung":[1492],"Bei":[1494],"allen":[1495,1531],"Statements,":[1496],"Handlungs-Empfehlung":[1499],"darstellen,":[1500],"ist":[1501],"St\u00e4rke":[1503],"Empfehlung":[1505],"anhand":[1506,1510],"Kennzeichnung":[1512],"Pfeilsymbol":[1515],"ersichtlich.":[1516],"Formulierungen":[1518],"Bedeutung":[1520],"Empfehlungsst\u00e4rken":[1522],"dargelegt.":[1529],"verkn\u00fcpft.":[1542],"Evidenz-":[1543],"Empfehlungsgrade":[1545],"vergeben.":[1551],"Konsensusst\u00e4rken.":[1554],"starker":[1555],"Zustimmung":[1557,1565,1575,1576,1587],">":[1559,1567,1578],"95":[1560,1570],"75":[1568,1581],"mehrheitliche":[1574],"50":[1579,1591],"weniger":[1589],"unmittelbar":[1598],"finanziert.":[1607],"Beeinflussung":[1610],"mussten":[1618],"Interessenkonflikte":[1620],"entsprechend":[1621],"AWMF-Vorgaben":[1623],"offenlegen.":[1624],"jeweiligen":[1626],"Ausf\u00fchrungen":[1627],"einzelnen":[1629],"Leitlinienmitglieder":[1630],"\u00dcbersichtstabelle":[1634],"Methodikreports":[1639],"zusammengefasst.":[1640],"Nach":[1641],"Einsch\u00e4tzung":[1642],"Koordinatoren":[1644],"ergab":[1645],"Interessenkonflikt,":[1649],"h\u00e4tte":[1655],"relevant":[1656],"verzerren":[1657],"Zusammenarbeit":[1664],"(DGIM),":[1671],"(DGAV),":[1684],"(DGK),":[1689]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":19},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
