{"id":"https://openalex.org/W119370613","doi":null,"title":"Lenses of diabetic patients \"yellow\" at an accelerated rate similar to older normals.","display_name":"Lenses of diabetic patients \"yellow\" at an accelerated rate similar to older normals.","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W119370613","mag":"119370613","pmid":"https://pubmed.ncbi.nlm.nih.gov/1987100"},"language":"en","primary_location":{"id":"pmid:1987100","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1987100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055404184","display_name":"Margaret Lutze","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Lutze","raw_affiliation_strings":["Department of Ophthalmology, University of Wisconsin, Madison"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, University of Wisconsin, Madison","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019952240","display_name":"George H. Bresnick","orcid":"https://orcid.org/0000-0001-9604-5403","observed_orcids":["https://orcid.org/0000-0001-9604-5403"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G H Bresnick","raw_affiliation_strings":["Department of Ophthalmology, University of Wisconsin\u2010Madison"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, University of Wisconsin\u2010Madison","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I135310074"],"apc_list":null,"apc_paid":null,"fwci":3.1426,"has_fulltext":false,"cited_by_count":76,"citation_normalized_percentile":{"value":0.91224077,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"32","issue":"1","first_page":"194","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.3411000072956085,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.3411000072956085,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.2451000064611435,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10381","display_name":"Ophthalmology and Visual Impairment Studies","score":0.12120000272989273,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lens-yellowing","display_name":"lens yellowing","score":0.7879999876022339},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.7200000286102295},{"id":"https://openalex.org/keywords/lens-transmission","display_name":"lens transmission","score":0.515999972820282},{"id":"https://openalex.org/keywords/lens-density","display_name":"lens density","score":0.5299999713897705},{"id":"https://openalex.org/keywords/accelerated-aging","display_name":"accelerated aging","score":0.7459999918937683},{"id":"https://openalex.org/keywords/glycosylation","display_name":"glycosylation","score":0.8149999976158142},{"id":"https://openalex.org/keywords/lens-proteins","display_name":"lens proteins","score":0.9160000085830688},{"id":"https://openalex.org/keywords/plasma-glucose","display_name":"plasma glucose","score":0.8930000066757202}],"concepts":[{"id":"https://openalex.org/C15336307","wikidata":"https://www.wikidata.org/wiki/Q1766051","display_name":"Lens (geology)","level":2,"score":0.7410645484924316},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6338094472885132},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5977681875228882},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.49052876234054565},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46765202283859253},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.31828898191452026},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18625473976135254},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003623","descriptor_name":"Dark Adaptation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007908","descriptor_name":"Lens, Crystalline","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007908","descriptor_name":"Lens, Crystalline","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011601","descriptor_name":"Psychophysics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1987100","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1987100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},{"id":"mag:119370613","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1987100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4581533663","display_name":"ELECTRORETINOGRAPHIC STUDIES IN DIABETIC RETINOPATHY","funder_award_id":"R01EY003084","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1979489445","https://openalex.org/W1993476219","https://openalex.org/W2077034296","https://openalex.org/W2088776000","https://openalex.org/W2129785995","https://openalex.org/W2412510738"],"related_works":["https://openalex.org/W4321070402","https://openalex.org/W2411057119","https://openalex.org/W124295472","https://openalex.org/W21556860","https://openalex.org/W2563572294","https://openalex.org/W1929337589","https://openalex.org/W2019247909","https://openalex.org/W2067443910","https://openalex.org/W7100213084","https://openalex.org/W2088824511"],"abstract_inverted_index":{"The":[0,19,70],"authors":[1],"used":[2],"a":[3],"psychophysical":[4],"method":[5],"to":[6,59,87],"measure":[7],"lens":[8,31,74,92,111,138,143],"transmission":[9,32],"of":[10,29,43,61,67,72,83,90,137],"young,":[11,44],"type":[12,45],"I":[13,46],"diabetic":[14,38,47,119],"patients":[15,48],"and":[16,35,121,131],"normal":[17,22,62,124],"controls.":[18],"results":[20],"from":[21,37],"controls":[23,63],"agreed":[24],"with":[25,33,80,98],"previously":[26],"published":[27],"reports":[28],"decreasing":[30],"age,":[34],"those":[36],"subjects":[39],"suggested":[40],"that":[41,56,60,76,94],"lenses":[42],"age":[49,66,100],"or":[50],"\"yellow\"":[51],"at":[52],"an":[53],"accelerated":[54,73,91,110,135],"rate":[55,71,89],"was":[57],"similar":[58,86],"over":[64,101],"the":[65,81,88,109,122],"60":[68,102],"yr.":[69,103],"density":[75,93],"occurs":[77,95],"per":[78,96],"year":[79,97],"duration":[82],"diabetes":[84],"is":[85,116],"patient":[99],"A":[104],"possible":[105],"molecular":[106],"explanation":[107],"for":[108],"yellowing":[112],"in":[113],"both":[114],"populations":[115,125],"discussed.":[117],"Both":[118],"individuals":[120],"older":[123],"have":[126,134],"elevated":[127],"plasma":[128],"glucose":[129],"levels":[130],"therefore":[132],"may":[133],"glycosylation":[136],"proteins":[139],"which":[140],"causes":[141],"increased":[142],"yellowing.":[144]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}