{"id":"https://openalex.org/W118596237","doi":null,"title":"Determinants of parental decision to abort or continue after non-aneuploid ultrasound-detected fetal abnormalities.","display_name":"Determinants of parental decision to abort or continue after non-aneuploid ultrasound-detected fetal abnormalities.","publication_year":1992,"publication_date":"1992-07-01","ids":{"openalex":"https://openalex.org/W118596237","mag":"118596237","pmid":"https://pubmed.ncbi.nlm.nih.gov/1603497"},"language":"en","primary_location":{"id":"pmid:1603497","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1603497","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031312989","display_name":"Peter G. Pryde","orcid":"https://orcid.org/0000-0001-8279-6943","observed_orcids":["https://orcid.org/0000-0001-8279-6943"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210130380","display_name":"Hutzel Women's Hospital","ror":"https://ror.org/02paek818","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800326109","https://openalex.org/I4210130380"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P G Pryde","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Michigan","institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210130380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111744586","display_name":"N B Isada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N B Isada","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015677560","display_name":"Mordechai Hallak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Hallak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113478915","display_name":"M P Johnson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M P Johnson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012204953","display_name":"A E Odgers","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A E Odgers","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103641815","display_name":"Mark I. Evans","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M I Evans","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0763,"has_fulltext":false,"cited_by_count":58,"citation_normalized_percentile":{"value":0.93022339,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"80","issue":"1","first_page":"52","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12716","display_name":"Congenital Anomalies and Fetal Surgery","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fetal-structural-anomalies","display_name":"fetal structural anomalies","score":0.640999972820282},{"id":"https://openalex.org/keywords/prenatal-ultrasound-diagnosis","display_name":"prenatal ultrasound diagnosis","score":0.5950000286102295},{"id":"https://openalex.org/keywords/abortion","display_name":"abortion","score":0.6959999799728394},{"id":"https://openalex.org/keywords/parental-decision-making","display_name":"parental decision-making","score":0.781000018119812},{"id":"https://openalex.org/keywords/gestational-age-at-diagnosis","display_name":"gestational age at diagnosis","score":0.8479999899864197},{"id":"https://openalex.org/keywords/neonatal-interventions","display_name":"neonatal interventions","score":0.8259999752044678}],"concepts":[{"id":"https://openalex.org/C2777549182","wikidata":"https://www.wikidata.org/wiki/Q15117556","display_name":"Abort","level":2,"score":0.9090635776519775},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8984564542770386},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.7071096897125244},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.699941873550415},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6287155151367188},{"id":"https://openalex.org/C50965678","wikidata":"https://www.wikidata.org/wiki/Q2724302","display_name":"Abnormality","level":2,"score":0.5755982398986816},{"id":"https://openalex.org/C2778642596","wikidata":"https://www.wikidata.org/wiki/Q8452","display_name":"Abortion","level":3,"score":0.5364867448806763},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.5134164094924927},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.473916620016098},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.45019981265068054},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.4456346035003662},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.4138812720775604},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3402351140975952},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.329079806804657},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.16698282957077026},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000013","descriptor_name":"Congenital Abnormalities","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000028","descriptor_name":"Abortion, Induced","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003657","descriptor_name":"Decision Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010290","descriptor_name":"Parents","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016216","descriptor_name":"Ultrasonography, Prenatal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037841","descriptor_name":"Pregnant People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:1603497","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1603497","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Journal Article"},{"id":"pmh:oai:repository.library.georgetown.edu:10822/544447","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10822/544447","pdf_url":null,"source":{"id":"https://openalex.org/S4306402467","display_name":"DigitalGeorgetown (Georgetown University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210145449","host_organization_name":"Center for Security and Emerging Technology","host_organization_lineage":["https://openalex.org/I4210145449"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"119115","raw_type":null},{"id":"mag:118596237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1603497","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2011245539","https://openalex.org/W4220765434","https://openalex.org/W2061121325","https://openalex.org/W2070337490","https://openalex.org/W2090017326","https://openalex.org/W1985809021","https://openalex.org/W2313502033","https://openalex.org/W2014817866","https://openalex.org/W2071152791","https://openalex.org/W767997433"],"abstract_inverted_index":{"OBJECTIVE:":[0],"This":[1,200],"study":[2],"evaluated":[3],"factors":[4],"influencing":[5],"the":[6,13,58,87,93,110,124,135,149,153,158,175,198],"decision":[7,94,154,176],"to":[8,95,155,177,196,202],"abort":[9,96,156,178],"after":[10,57],"abnormalities":[11,29,47,189],"in":[12,109,174,212],"karyotypically":[14],"normal":[15],"fetus":[16],"were":[17,48,54,72,104,209],"found":[18],"through":[19,37],"ultrasonography.":[20],"METHODS:":[21],"We":[22],"reviewed":[23],"all":[24],"pregnancies":[25,141],"complicated":[26],"by":[27,215],"ultrasound-detected":[28],"managed":[30],"on":[31],"our":[32],"service":[33],"from":[34],"April":[35],"1990":[36],"August":[38],"1991":[39],"(N":[40,50,65],"=":[41,51,66],"262).":[42],"Cases":[43],"with":[44,92,142,188,191],"associated":[45,190],"karyotypic":[46],"excluded":[49],"35),":[52],"as":[53],"cases":[55,71],"diagnosed":[56],"legal":[59],"gestational":[60,126,165],"age":[61,127,166],"limit":[62],"for":[63,179,206],"abortion":[64],"68).":[67],"The":[68,83,117,164],"remaining":[69],"159":[70],"stratified":[73],"into":[74],"prognosis":[75],"groups":[76],"of":[77,86,102,146,152,160],"\"severe,\"":[78],"\"uncertain,\"":[79,112],"and":[80,107,113,121,123],"\"mild.\"":[81],"RESULTS:":[82],"prognostic":[84],"severity":[85,159],"ultrasound":[88,144],"abnormality":[89],"strongly":[90],"correlated":[91],"(P":[97],"less":[98],"than":[99],".0001).":[100],"Rates":[101],"termination":[103],"0,":[105],"12,":[106],"66%":[108],"\"mild,\"":[111],"\"severe\"":[114],"groups,":[115],"respectively.":[116],"patients'":[118],"age,":[119],"gravidity,":[120],"parity,":[122],"fetal":[125,147,161,180],"at":[128,167],"diagnosis":[129,145,168],"did":[130],"not":[131,170],"differ":[132],"significantly":[133],"between":[134],"groups.":[136],"CONCLUSIONS:":[137],"1)":[138],"In":[139],"non-aneuploid":[140],"an":[143,171],"abnormality,":[148],"major":[150],"predictor":[151],"was":[157,169],"prognosis.":[162],"2)":[163],"important":[172],"variable":[173],"structural":[181],"abnormalities.":[182],"3)":[183],"Parents":[184],"who":[185],"had":[186],"fetuses":[187],"uncertain":[192],"prognoses":[193],"usually":[194],"opted":[195],"continue":[197],"pregnancy.":[199],"appeared":[201],"be":[203],"particularly":[204],"true":[205],"defects":[207],"that":[208],"potentially":[210],"correctable":[211],"utero":[213],"or":[214],"neonatal":[216],"intervention":[217],"(even":[218],"if":[219],"investigational).":[220]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}