{"id":"https://openalex.org/W118090679","doi":"https://doi.org/10.1007/978-1-4614-7645-0_17","title":"Tumor Phylogenetics in the NGS Era: Strategies, Challenges, and Future Prospects","display_name":"Tumor Phylogenetics in the NGS Era: Strategies, Challenges, and Future Prospects","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W118090679","doi":"https://doi.org/10.1007/978-1-4614-7645-0_17","mag":"118090679"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4614-7645-0_17","doi":"https://doi.org/10.1007/978-1-4614-7645-0_17","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4614-7645-0_17","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Next Generation Sequencing in Cancer Research","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2488005911","display_name":"Next Generation Sequencing in Cancer Research"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031387460","display_name":"Ayshwarya Subramanian","orcid":"https://orcid.org/0000-0002-4134-7612","observed_orcids":["https://orcid.org/0000-0002-4134-7612"]},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayshwarya Subramanian","raw_affiliation_strings":["Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, 15213, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, 15213, USA","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027859218","display_name":"Stanley E. Shackney","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stanley Shackney","raw_affiliation_strings":["Intelligent Oncotherapeutics, LLP, Pittsburgh, PA, 15243, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intelligent Oncotherapeutics, LLP, Pittsburgh, PA, 15243, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051953313","display_name":"Russell S. Schwartz","orcid":"https://orcid.org/0000-0002-4970-2252","observed_orcids":["https://orcid.org/0000-0002-4970-2252"]},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Russell Schwartz","raw_affiliation_strings":["Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, 15213, USA","Lane Center for Computational Biology, Carnegie Mellon University, Pittsburgh, PA, 15213, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, 15213, USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Lane Center for Computational Biology, Carnegie Mellon University, Pittsburgh, PA, 15213, USA","institution_ids":["https://openalex.org/I74973139"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051953313"],"corresponding_institution_ids":["https://openalex.org/I74973139"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08477237,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"335","last_page":"357"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tumor-evolution","display_name":"tumor evolution","score":0.7919999957084656},{"id":"https://openalex.org/keywords/phylogenetic-reconstruction","display_name":"phylogenetic inference","score":0.9020000100135803},{"id":"https://openalex.org/keywords/tumor-heterogeneity","display_name":"tumor heterogeneity","score":0.7350000143051147},{"id":"https://openalex.org/keywords/tumor-subtypes","display_name":"tumor subtypes","score":0.8169999718666077},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.4909999966621399},{"id":"https://openalex.org/keywords/whole-genome-sequencing","display_name":"whole genome sequencing","score":0.7739999890327454},{"id":"https://openalex.org/keywords/next-generation-sequencing","display_name":"next-generation sequencing","score":0.8090000152587891},{"id":"https://openalex.org/keywords/somatic-mutations","display_name":"somatic mutations","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.7729945182800293},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.6955472826957703},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6026598215103149},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5712551474571228},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4914041757583618},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.4714062213897705},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4182506203651428},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.37309569120407104},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32751747965812683},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.24587422609329224},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19127368927001953},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12601405382156372}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4614-7645-0_17","doi":"https://doi.org/10.1007/978-1-4614-7645-0_17","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4614-7645-0_17","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Next Generation Sequencing in Cancer Research","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":110,"referenced_works":["https://openalex.org/W116063010","https://openalex.org/W188996788","https://openalex.org/W1504702575","https://openalex.org/W1536971344","https://openalex.org/W1575092008","https://openalex.org/W1881971346","https://openalex.org/W1915587770","https://openalex.org/W1937941822","https://openalex.org/W1964154017","https://openalex.org/W1967304777","https://openalex.org/W1968328642","https://openalex.org/W1968393646","https://openalex.org/W1989169241","https://openalex.org/W1989825702","https://openalex.org/W1990085600","https://openalex.org/W1999463736","https://openalex.org/W2000111986","https://openalex.org/W2001258296","https://openalex.org/W2009569945","https://openalex.org/W2014982185","https://openalex.org/W2016531291","https://openalex.org/W2017220980","https://openalex.org/W2020627627","https://openalex.org/W2025183726","https://openalex.org/W2030345723","https://openalex.org/W2030447420","https://openalex.org/W2032518018","https://openalex.org/W2034629821","https://openalex.org/W2035593347","https://openalex.org/W2042536531","https://openalex.org/W2045582876","https://openalex.org/W2046601740","https://openalex.org/W2047823654","https://openalex.org/W2047928920","https://openalex.org/W2048844098","https://openalex.org/W2053256077","https://openalex.org/W2055598216","https://openalex.org/W2055764798","https://openalex.org/W2056025993","https://openalex.org/W2056126445","https://openalex.org/W2060761276","https://openalex.org/W2065288894","https://openalex.org/W2067507447","https://openalex.org/W2073294762","https://openalex.org/W2077858999","https://openalex.org/W2091870725","https://openalex.org/W2093573907","https://openalex.org/W2093890858","https://openalex.org/W2095268740","https://openalex.org/W2096128575","https://openalex.org/W2097255042","https://openalex.org/W2097348296","https://openalex.org/W2097706568","https://openalex.org/W2098225187","https://openalex.org/W2098608887","https://openalex.org/W2101250487","https://openalex.org/W2104078444","https://openalex.org/W2105054044","https://openalex.org/W2105644651","https://openalex.org/W2108187125","https://openalex.org/W2108234281","https://openalex.org/W2108698786","https://openalex.org/W2109077054","https://openalex.org/W2109363337","https://openalex.org/W2109596230","https://openalex.org/W2112641584","https://openalex.org/W2113633750","https://openalex.org/W2114204060","https://openalex.org/W2115162083","https://openalex.org/W2117013689","https://openalex.org/W2117649404","https://openalex.org/W2117692326","https://openalex.org/W2120819924","https://openalex.org/W2123558100","https://openalex.org/W2123576600","https://openalex.org/W2124442734","https://openalex.org/W2124810156","https://openalex.org/W2126903025","https://openalex.org/W2131994307","https://openalex.org/W2133174470","https://openalex.org/W2134535550","https://openalex.org/W2134706183","https://openalex.org/W2135640980","https://openalex.org/W2139465853","https://openalex.org/W2140817080","https://openalex.org/W2141913814","https://openalex.org/W2142097336","https://openalex.org/W2142518990","https://openalex.org/W2143093088","https://openalex.org/W2148930557","https://openalex.org/W2149573463","https://openalex.org/W2149843794","https://openalex.org/W2150160098","https://openalex.org/W2150575159","https://openalex.org/W2152576550","https://openalex.org/W2161444534","https://openalex.org/W2163166770","https://openalex.org/W2163584430","https://openalex.org/W2166542854","https://openalex.org/W2167383891","https://openalex.org/W2170958846","https://openalex.org/W2171170496","https://openalex.org/W2179763962","https://openalex.org/W2179893475","https://openalex.org/W2610167300","https://openalex.org/W3186215825","https://openalex.org/W3199943451","https://openalex.org/W4233815609","https://openalex.org/W4285719527","https://openalex.org/W4388212639"],"related_works":["https://openalex.org/W104023327","https://openalex.org/W3206046625","https://openalex.org/W2588969809","https://openalex.org/W2939491123","https://openalex.org/W1968393646","https://openalex.org/W2562231496","https://openalex.org/W2595259427","https://openalex.org/W3094384887","https://openalex.org/W7163018979","https://openalex.org/W2078529459"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}
