{"id":"https://openalex.org/W117153264","doi":null,"title":"Trypanosoma brucei brucei infected rats: micronucleated polychromatic erythrocytes.","display_name":"Trypanosoma brucei brucei infected rats: micronucleated polychromatic erythrocytes.","publication_year":2014,"publication_date":"2014-06-01","ids":{"openalex":"https://openalex.org/W117153264","mag":"117153264","pmid":"https://pubmed.ncbi.nlm.nih.gov/25134900"},"language":"en","primary_location":{"id":"pmid:25134900","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25134900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical biomedicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087486248","display_name":"Nathan Habila","orcid":"https://orcid.org/0000-0003-4186-895X","observed_orcids":["https://orcid.org/0000-0003-4186-895X"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"N Habila","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054446344","display_name":"Aliyu Idris Muhammad","orcid":"https://orcid.org/0000-0002-4167-7793","observed_orcids":["https://orcid.org/0000-0002-4167-7793"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"A Muhammad","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055847897","display_name":"Idowu Asegame Aimola","orcid":"https://orcid.org/0000-0001-7553-438X","observed_orcids":["https://orcid.org/0000-0001-7553-438X"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"I A Aimola","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039488538","display_name":"Gloria Dada Chechet","orcid":"https://orcid.org/0000-0003-2741-3940","observed_orcids":["https://orcid.org/0000-0003-2741-3940"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"G D Chechet","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083109904","display_name":"Mohammed Auwal Ibrahim","orcid":"https://orcid.org/0000-0002-0680-3889","observed_orcids":["https://orcid.org/0000-0002-0680-3889"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"M A Ibrahim","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018837184","display_name":"J A Kwanashie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"J A Kwanashie","raw_affiliation_strings":["Department of Crop Protection, Ahmadu Bello University, Zaria-Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Crop Protection, Ahmadu Bello University, Zaria-Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034253746","display_name":"O E Oche","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"O E Oche","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010729706","display_name":"Oyeronke A. Odunola","orcid":"https://orcid.org/0000-0002-2440-4400","observed_orcids":["https://orcid.org/0000-0002-2440-4400"]},"institutions":[{"id":"https://openalex.org/I181631907","display_name":"University of Ibadan","ror":"https://ror.org/03wx2rr30","country_code":"NG","type":"education","lineage":["https://openalex.org/I181631907"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"A O Odunola","raw_affiliation_strings":["Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, University of Ibadan, Ibadan, Oyo State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, University of Ibadan, Ibadan, Oyo State, Nigeria","institution_ids":["https://openalex.org/I181631907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2341,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.55839497,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"31","issue":"2","first_page":"312","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.04170000180602074,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trypanosoma-brucei-brucei","display_name":"Trypanosoma brucei brucei","score":1.0},{"id":"https://openalex.org/keywords/trypanosomiasis","display_name":"trypanosomiasis","score":0.8999999761581421},{"id":"https://openalex.org/keywords/genotoxicity","display_name":"genotoxicity","score":0.7059999704360962},{"id":"https://openalex.org/keywords/hematological-changes","display_name":"hematological changes","score":0.6899999976158142},{"id":"https://openalex.org/keywords/parasitemia","display_name":"parasitemia","score":0.902999997138977},{"id":"https://openalex.org/keywords/acute-infection","display_name":"acute infection","score":0.6050000190734863},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.578000009059906},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.9119549989700317},{"id":"https://openalex.org/C2779502636","wikidata":"https://www.wikidata.org/wiki/Q33244","display_name":"Trypanosoma brucei","level":3,"score":0.8670641183853149},{"id":"https://openalex.org/C2775867548","wikidata":"https://www.wikidata.org/wiki/Q1897162","display_name":"Parasitemia","level":4,"score":0.8512015342712402},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8251457214355469},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.7998678684234619},{"id":"https://openalex.org/C36681516","wikidata":"https://www.wikidata.org/wiki/Q1700733","display_name":"Micronucleus","level":4,"score":0.579382061958313},{"id":"https://openalex.org/C2778143080","wikidata":"https://www.wikidata.org/wiki/Q2443552","display_name":"Trypanosomiasis","level":2,"score":0.5542951822280884},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.5355486869812012},{"id":"https://openalex.org/C2776557347","wikidata":"https://www.wikidata.org/wiki/Q37187","display_name":"Red blood cell","level":2,"score":0.46758413314819336},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.42738598585128784},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.40491437911987305},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3811894357204437},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3250483572483063},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.22923243045806885},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22790050506591797},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.1323060393333435},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.10911485552787781},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08783003687858582},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0776042640209198},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.059935808181762695}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014346","descriptor_name":"Trypanosoma brucei brucei","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D014353","descriptor_name":"Trypanosomiasis, African","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015162","descriptor_name":"Micronucleus Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:25134900","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25134900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical biomedicine","raw_type":"Journal Article"},{"id":"mag:117153264","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25134900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1535982994","https://openalex.org/W1851532174","https://openalex.org/W1965124451","https://openalex.org/W1965636070","https://openalex.org/W1970144610","https://openalex.org/W1971807222","https://openalex.org/W1980680362","https://openalex.org/W1982183962","https://openalex.org/W1986742049","https://openalex.org/W1992577456","https://openalex.org/W1995652767","https://openalex.org/W1998585740","https://openalex.org/W2016154498","https://openalex.org/W2019624290","https://openalex.org/W2033073182","https://openalex.org/W2045879344","https://openalex.org/W2055788781","https://openalex.org/W2056626833","https://openalex.org/W2063270897","https://openalex.org/W2075308902","https://openalex.org/W2087175643","https://openalex.org/W2096889430","https://openalex.org/W2098831797","https://openalex.org/W2102654240","https://openalex.org/W2110732081","https://openalex.org/W2117650737"],"related_works":["https://openalex.org/W1986110668","https://openalex.org/W2597829786","https://openalex.org/W7016995085","https://openalex.org/W2183514841","https://openalex.org/W2055751724","https://openalex.org/W2106326024","https://openalex.org/W2408471533","https://openalex.org/W2125427758","https://openalex.org/W2098492061","https://openalex.org/W1190640312"],"abstract_inverted_index":{"The":[0,48,77],"emergence":[1],"of":[2,52,102,110,125],"bone":[3,24],"marrow":[4,25,31],"micronucleated":[5],"polychromatic":[6],"erythrocytes":[7],"(MN-PCE)":[8],"in":[9,19,27,82,94,114,122],"rats":[10,68,115],"experimentally":[11],"infected":[12,43,69],"with":[13,91],"Trypanosoma":[14],"brucei":[15,16,113],"was":[17,32,104],"examined":[18],"order":[20],"to":[21,133],"understand":[22],"the":[23,100,123,126],"effects":[26],"trypanosomiasis":[28],"infection.":[29],"Bone":[30],"collected":[33,41],"for":[34,45,67,70],"micronucleus":[35],"assay":[36],"while":[37],"blood":[38,89],"samples":[39],"were":[40],"from":[42],"rat":[44],"hematological":[46],"analysis.":[47],"results":[49],"showed":[50],"evidence":[51],"MN-PCE":[53,103],"at":[54],"12.75":[55],"\u00b1":[56,63],"0.65":[57],"micronuclei/":[58],"1000":[59],"PCE":[60,66],"and":[61,73,87,116],"9.60":[62],"2.95":[64],"micronuclei/1000":[65],"21":[71],"days":[72,75],"14":[74],"respectively.":[76],"hematology":[78],"examination":[79],"revealed":[80,98],"changes":[81],"packed":[83],"cell":[84],"volume,":[85],"haemoglobin":[86],"red":[88],"cells":[90],"concomitant":[92],"increase":[93],"parasitemia.":[95],"This":[96],"study":[97],"that":[99,128],"generation":[101],"induced":[105],"by":[106],"an":[107,119],"acute":[108],"infection":[109],"T.":[111],"b.":[112],"this":[117],"highlights":[118],"important":[120],"phase":[121],"pathogenesis":[124],"disease":[127],"may":[129],"indicate":[130],"possible":[131],"damage":[132],"genetic":[134],"information.":[135]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}