{"id":"https://openalex.org/W117129271","doi":"https://doi.org/10.1007/978-1-59259-736-9_21","title":"Control of Osteoblast Function and Bone Extracellular Matrix Mineralization by Vitamin D","display_name":"Control of Osteoblast Function and Bone Extracellular Matrix Mineralization by Vitamin D","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W117129271","doi":"https://doi.org/10.1007/978-1-59259-736-9_21","mag":"117129271"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-59259-736-9_21","doi":"https://doi.org/10.1007/978-1-59259-736-9_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-59259-736-9_21","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Skeleton","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4243786036","display_name":"The Skeleton"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088091678","display_name":"Johannes P.T.M. van Leeuwen","orcid":"https://orcid.org/0000-0002-2282-4006","observed_orcids":["https://orcid.org/0000-0002-2282-4006","https://orcid.org/0000-0001-8503-6958"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Johannes P. T. M. van Leeuwen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110028849","display_name":"Marjolein van Driel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marjolein van Driel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5114003949","display_name":"Hulbert A. P. Pols","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hulbert A. P. Pols","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7167,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.86234022,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"307","last_page":"332"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":1.0},{"id":"https://openalex.org/keywords/osteoblast-activity","display_name":"osteoblast activity","score":0.9480000138282776},{"id":"https://openalex.org/keywords/vitamin-d-receptor","display_name":"vitamin D receptor","score":0.8119999766349792},{"id":"https://openalex.org/keywords/rickets","display_name":"rickets","score":0.8550000190734863},{"id":"https://openalex.org/keywords/calcium-homeostasis","display_name":"calcium homeostasis","score":0.9729999899864197},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.6930000185966492},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7924367785453796},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7445313930511475},{"id":"https://openalex.org/C2776489590","wikidata":"https://www.wikidata.org/wiki/Q183392","display_name":"Rickets","level":3,"score":0.7220958471298218},{"id":"https://openalex.org/C179639408","wikidata":"https://www.wikidata.org/wiki/Q417057","display_name":"Calcitriol receptor","level":3,"score":0.6906135082244873},{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.6645838618278503},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.6531835198402405},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.5306687951087952},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.5118629336357117},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4980030059814453},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.4878397285938263},{"id":"https://openalex.org/C2779740938","wikidata":"https://www.wikidata.org/wiki/Q4138762","display_name":"vitamin D deficiency","level":3,"score":0.4474772810935974},{"id":"https://openalex.org/C111696902","wikidata":"https://www.wikidata.org/wiki/Q6864413","display_name":"Mineralization (soil science)","level":3,"score":0.41779589653015137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32756179571151733},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21162310242652893},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11239087581634521},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06408920884132385},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C537208039","wikidata":"https://www.wikidata.org/wiki/Q627","display_name":"Nitrogen","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/978-1-59259-736-9_21","doi":"https://doi.org/10.1007/978-1-59259-736-9_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-59259-736-9_21","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Skeleton","raw_type":"book-chapter"},{"id":"pmh:eur:oai:pure.eur.nl:publications/6fd903b3-50c5-4383-8a96-c03ef272b178","doi":null,"is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/6fd903b3-50c5-4383-8a96-c03ef272b178","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Skeleton: biochemical, genetic,and molecular interactions in development and homeostasis., 307 - 332","raw_type":"info:eu-repo/semantics/bookpart"},{"id":"pmh:oai:pure.eur.nl:openaire_cris_publications/6fd903b3-50c5-4383-8a96-c03ef272b178","doi":null,"is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/6fd903b3-50c5-4383-8a96-c03ef272b178","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"van Leeuwen, H, Driel, M & Pols, H 2004, Control of osteoblast function and bone extracellular matrix mineralization by vitamin D. in EJ Massaro & JM Rogers (eds), The Skeleton: biochemical, genetic,and molecular interactions in development and homeostasis.. Humana Press Inc, Totowa, pp. 307-332.","raw_type":"info:eu-repo/semantics/bookPart"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.766700029373169}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":333,"referenced_works":["https://openalex.org/W30516660","https://openalex.org/W53273794","https://openalex.org/W142967008","https://openalex.org/W633735835","https://openalex.org/W1482092913","https://openalex.org/W1483809793","https://openalex.org/W1489729774","https://openalex.org/W1491020898","https://openalex.org/W1501084548","https://openalex.org/W1519499635","https://openalex.org/W1521828067","https://openalex.org/W1527588610","https://openalex.org/W1529465070","https://openalex.org/W1537090264","https://openalex.org/W1553049056","https://openalex.org/W1557149681","https://openalex.org/W1564323166","https://openalex.org/W1576923208","https://openalex.org/W1695610564","https://openalex.org/W1708518265","https://openalex.org/W1890394592","https://openalex.org/W1943239370","https://openalex.org/W1963816194","https://openalex.org/W1963882270","https://openalex.org/W1964174955","https://openalex.org/W1964721682","https://openalex.org/W1964874260","https://openalex.org/W1966170252","https://openalex.org/W1966976296","https://openalex.org/W1968241785","https://openalex.org/W1968869424","https://openalex.org/W1971067879","https://openalex.org/W1971158606","https://openalex.org/W1971445361","https://openalex.org/W1971931989","https://openalex.org/W1972037841","https://openalex.org/W1972107464","https://openalex.org/W1972304250","https://openalex.org/W1972451601","https://openalex.org/W1972556179","https://openalex.org/W1972599893","https://openalex.org/W1972950322","https://openalex.org/W1973392312","https://openalex.org/W1974366297","https://openalex.org/W1974659965","https://openalex.org/W1974853113","https://openalex.org/W1975224992","https://openalex.org/W1975716976","https://openalex.org/W1977196589","https://openalex.org/W1977875815","https://openalex.org/W1977950612","https://openalex.org/W1978593433","https://openalex.org/W1981582835","https://openalex.org/W1981595493","https://openalex.org/W1983990225","https://openalex.org/W1985414693","https://openalex.org/W1985434939","https://openalex.org/W1985812086","https://openalex.org/W1986000416","https://openalex.org/W1988683928","https://openalex.org/W1989042099","https://openalex.org/W1989164151","https://openalex.org/W1989569585","https://openalex.org/W1989572590","https://openalex.org/W1990386002","https://openalex.org/W1990493556","https://openalex.org/W1990591325","https://openalex.org/W1990900725","https://openalex.org/W1990935283","https://openalex.org/W1992602047","https://openalex.org/W1993819824","https://openalex.org/W1993990815","https://openalex.org/W1995546038","https://openalex.org/W1995575762","https://openalex.org/W1995862119","https://openalex.org/W1996203783","https://openalex.org/W1996691196","https://openalex.org/W1997697459","https://openalex.org/W1999520741","https://openalex.org/W1999917020","https://openalex.org/W2000822822","https://openalex.org/W2001121103","https://openalex.org/W2002875264","https://openalex.org/W2003991299","https://openalex.org/W2004907776","https://openalex.org/W2004930284","https://openalex.org/W2005296604","https://openalex.org/W2007091948","https://openalex.org/W2008374372","https://openalex.org/W2008544782","https://openalex.org/W2010846442","https://openalex.org/W2010870415","https://openalex.org/W2010960003","https://openalex.org/W2011198003","https://openalex.org/W2011649728","https://openalex.org/W2011927327","https://openalex.org/W2012014125","https://openalex.org/W2012333093","https://openalex.org/W2012978387","https://openalex.org/W2013242986","https://openalex.org/W2013482945","https://openalex.org/W2013850508","https://openalex.org/W2015020531","https://openalex.org/W2015496410","https://openalex.org/W2015547112","https://openalex.org/W2016537897","https://openalex.org/W2017015835","https://openalex.org/W2017038501","https://openalex.org/W2017859346","https://openalex.org/W2018155868","https://openalex.org/W2018497749","https://openalex.org/W2018809127","https://openalex.org/W2019113771","https://openalex.org/W2019353790","https://openalex.org/W2019417087","https://openalex.org/W2020067119","https://openalex.org/W2020874304","https://openalex.org/W2021099662","https://openalex.org/W2021323848","https://openalex.org/W2021653464","https://openalex.org/W2022217449","https://openalex.org/W2023845557","https://openalex.org/W2024081735","https://openalex.org/W2024871259","https://openalex.org/W2026330507","https://openalex.org/W2027878661","https://openalex.org/W2027881211","https://openalex.org/W2029347271","https://openalex.org/W2030205954","https://openalex.org/W2030908725","https://openalex.org/W2030951215","https://openalex.org/W2031705624","https://openalex.org/W2031930348","https://openalex.org/W2032286996","https://openalex.org/W2032653240","https://openalex.org/W2032776490","https://openalex.org/W2033004685","https://openalex.org/W2033187542","https://openalex.org/W2033231214","https://openalex.org/W2033592063","https://openalex.org/W2033919638","https://openalex.org/W2033971261","https://openalex.org/W2034386950","https://openalex.org/W2035087930","https://openalex.org/W2035845888","https://openalex.org/W2036380902","https://openalex.org/W2037761234","https://openalex.org/W2038012173","https://openalex.org/W2039448824","https://openalex.org/W2040137910","https://openalex.org/W2040552779","https://openalex.org/W2042037577","https://openalex.org/W2042713071","https://openalex.org/W2042721916","https://openalex.org/W2042887349","https://openalex.org/W2043033796","https://openalex.org/W2045000145","https://openalex.org/W2045561085","https://openalex.org/W2046409934","https://openalex.org/W2046932891","https://openalex.org/W2047044760","https://openalex.org/W2047182075","https://openalex.org/W2047347345","https://openalex.org/W2047632227","https://openalex.org/W2047656173","https://openalex.org/W2048662055","https://openalex.org/W2048873273","https://openalex.org/W2049109419","https://openalex.org/W2049746083","https://openalex.org/W2050867626","https://openalex.org/W2051874740","https://openalex.org/W2052232074","https://openalex.org/W2053611977","https://openalex.org/W2054362917","https://openalex.org/W2054604495","https://openalex.org/W2055028932","https://openalex.org/W2055224067","https://openalex.org/W2055338052","https://openalex.org/W2055504706","https://openalex.org/W2055673006","https://openalex.org/W2058579856","https://openalex.org/W2058691287","https://openalex.org/W2058750989","https://openalex.org/W2058766023","https://openalex.org/W2058800758","https://openalex.org/W2058838706","https://openalex.org/W2062270413","https://openalex.org/W2062290662","https://openalex.org/W2062588151","https://openalex.org/W2062972824","https://openalex.org/W2063407079","https://openalex.org/W2063664011","https://openalex.org/W2063987586","https://openalex.org/W2064683965","https://openalex.org/W2065546558","https://openalex.org/W2065694321","https://openalex.org/W2065780064","https://openalex.org/W2066104914","https://openalex.org/W2066144690","https://openalex.org/W2067118606","https://openalex.org/W2067171350","https://openalex.org/W2067872631","https://openalex.org/W2067993173","https://openalex.org/W2068521053","https://openalex.org/W2068678088","https://openalex.org/W2069258124","https://openalex.org/W2069309983","https://openalex.org/W2069979659","https://openalex.org/W2070027660","https://openalex.org/W2070167568","https://openalex.org/W2070667772","https://openalex.org/W2072256043","https://openalex.org/W2072423174","https://openalex.org/W2072480224","https://openalex.org/W2074696981","https://openalex.org/W2074789698","https://openalex.org/W2075151279","https://openalex.org/W2075700478","https://openalex.org/W2075833408","https://openalex.org/W2076655658","https://openalex.org/W2077559627","https://openalex.org/W2078119270","https://openalex.org/W2078423621","https://openalex.org/W2078978436","https://openalex.org/W2079230724","https://openalex.org/W2079442568","https://openalex.org/W2079736991","https://openalex.org/W2079762638","https://openalex.org/W2080572028","https://openalex.org/W2081047941","https://openalex.org/W2081259002","https://openalex.org/W2081470188","https://openalex.org/W2082212016","https://openalex.org/W2084623555","https://openalex.org/W2085943835","https://openalex.org/W2086068321","https://openalex.org/W2086219448","https://openalex.org/W2086683059","https://openalex.org/W2087100948","https://openalex.org/W2087255769","https://openalex.org/W2088637374","https://openalex.org/W2090464853","https://openalex.org/W2092723956","https://openalex.org/W2092804172","https://openalex.org/W2092806266","https://openalex.org/W2092948213","https://openalex.org/W2094291999","https://openalex.org/W2094338166","https://openalex.org/W2094425445","https://openalex.org/W2095518256","https://openalex.org/W2097191932","https://openalex.org/W2099056711","https://openalex.org/W2099438166","https://openalex.org/W2099551278","https://openalex.org/W2104519624","https://openalex.org/W2105024913","https://openalex.org/W2105491559","https://openalex.org/W2106197569","https://openalex.org/W2107131674","https://openalex.org/W2108571742","https://openalex.org/W2109608328","https://openalex.org/W2111291015","https://openalex.org/W2111378405","https://openalex.org/W2112953209","https://openalex.org/W2114230491","https://openalex.org/W2114528551","https://openalex.org/W2114948431","https://openalex.org/W2117106626","https://openalex.org/W2118835331","https://openalex.org/W2119119706","https://openalex.org/W2121096379","https://openalex.org/W2121780717","https://openalex.org/W2122112217","https://openalex.org/W2124768014","https://openalex.org/W2129812644","https://openalex.org/W2130281902","https://openalex.org/W2133562234","https://openalex.org/W2136376840","https://openalex.org/W2136414742","https://openalex.org/W2136498711","https://openalex.org/W2139640000","https://openalex.org/W2141486993","https://openalex.org/W2145708538","https://openalex.org/W2146200346","https://openalex.org/W2147428009","https://openalex.org/W2148507006","https://openalex.org/W2150721897","https://openalex.org/W2153156904","https://openalex.org/W2153663000","https://openalex.org/W2154102213","https://openalex.org/W2155561263","https://openalex.org/W2156422955","https://openalex.org/W2157732592","https://openalex.org/W2161061874","https://openalex.org/W2161983593","https://openalex.org/W2162088346","https://openalex.org/W2162946316","https://openalex.org/W2163895773","https://openalex.org/W2167405461","https://openalex.org/W2167714900","https://openalex.org/W2169357450","https://openalex.org/W2169897886","https://openalex.org/W2170232732","https://openalex.org/W2184391580","https://openalex.org/W2304774880","https://openalex.org/W2314110838","https://openalex.org/W2315992235","https://openalex.org/W2324537316","https://openalex.org/W2331052920","https://openalex.org/W2335681019","https://openalex.org/W2336000481","https://openalex.org/W2345294145","https://openalex.org/W2396338222","https://openalex.org/W2400408360","https://openalex.org/W2404480779","https://openalex.org/W2406489612","https://openalex.org/W2408035150","https://openalex.org/W2411760157","https://openalex.org/W2415882316","https://openalex.org/W2417972591","https://openalex.org/W4211200865","https://openalex.org/W4232275671","https://openalex.org/W4233708126","https://openalex.org/W4242052585","https://openalex.org/W4245222516","https://openalex.org/W4246156072","https://openalex.org/W4247351964","https://openalex.org/W4252200616","https://openalex.org/W4252973580","https://openalex.org/W4253057573","https://openalex.org/W4256733803","https://openalex.org/W4299353467","https://openalex.org/W4322388195"],"related_works":["https://openalex.org/W2028813486","https://openalex.org/W2621643496","https://openalex.org/W2091741388","https://openalex.org/W2528748261","https://openalex.org/W3212138639","https://openalex.org/W2013072943","https://openalex.org/W1999924012","https://openalex.org/W4317036473","https://openalex.org/W2110018909","https://openalex.org/W7005609819"],"abstract_inverted_index":{"Vitamin":[0,102,127,135,165],"D":[1,30,57,71,87,99,103,112,128,136,166],"is":[2,67,106],"the":[3,11,19,28,48,97,114,138],"major":[4],"regulator":[5],"of":[6,50,116,126,140,164],"calcium":[7,14,91],"homeostasis":[8],"and":[9,24,40,79,83,110,124,132,142],"protects":[10],"organism":[12],"from":[13],"deficiency":[15],"via":[16],"effects":[17,46,63],"on":[18,47,64,76,129],"intestine,":[20],"kidney,":[21],"parathyroid":[22],"gland,":[23],"bone.":[25,51,65],"Disturbances":[26],"in":[27,44,84,108,119,146,152],"vitamin":[29,35,56,70,86,98,111],"endocrine":[31],"system,":[32],"for":[33],"example,":[34],"D-dependent":[36],"rickets":[37,82],"type":[38,41],"I":[39],"II,":[42],"result":[43],"profound":[45],"mineralization":[49],"Also,":[52],"recent":[53],"studies":[54],"with":[55,154,167],"receptor":[58,88,100],"(VDR)":[59],"knockout":[60,89],"mice":[61],"show":[62],"It":[66],"questioned":[68],"whether":[69],"has":[72],"a":[73],"direct":[74],"effect":[75],"bone":[77,94],"formation":[78],"mineralization.":[80,95],"In":[81],"particular":[85],"mice,":[90],"supplementation":[92],"restores":[93],"However,":[96],"(see":[101,121,160],"Receptor":[104],"section)":[105],"present":[107],"osteoblasts,":[109],"affects":[113],"expression":[115,139],"various":[117],"genes":[118,141],"osteoblasts":[120],"Introduction:":[122],"Osteoblasts":[123],"Effects":[125],"Osteoblast":[130],"Function":[131],"Mineralization":[133],"sections).":[134],"regulates":[137],"osteoblast":[143],"activity":[144],"not":[145],"an":[147],"independent":[148],"manner":[149],"but":[150],"often":[151],"interaction":[153],"other":[155],"hormones":[156],"and/or":[157],"growth":[158],"factors":[159],"section":[161],"titled":[162],"Interaction":[163],"Other":[168],"Factors).":[169]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}