{"id":"https://openalex.org/W116571673","doi":null,"title":"Role of nitric oxide in developmental biology in plants, bacteria, and man.","display_name":"Role of nitric oxide in developmental biology in plants, bacteria, and man.","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W116571673","mag":"116571673","pmid":"https://pubmed.ncbi.nlm.nih.gov/24563585","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3930063"},"language":"en","primary_location":{"id":"pmid:24563585","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24563585","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current topics in pharmacology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3930063","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087465915","display_name":"Alexander V. Allain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander V Allain","raw_affiliation_strings":["Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010254355","display_name":"Van T. Hoang","orcid":"https://orcid.org/0000-0002-1561-0915","observed_orcids":["https://orcid.org/0000-0002-1561-0915"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Van T Hoang","raw_affiliation_strings":["Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003827020","display_name":"George F. Lasker","orcid":"https://orcid.org/0000-0002-2244-5946","observed_orcids":["https://orcid.org/0000-0002-2244-5946"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George F Lasker","raw_affiliation_strings":["Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063125816","display_name":"Edward A. Pankey","orcid":"https://orcid.org/0000-0001-9039-280X","observed_orcids":["https://orcid.org/0000-0001-9039-280X"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward A Pankey","raw_affiliation_strings":["Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060968419","display_name":"Subramanyam N. Murthy","orcid":"https://orcid.org/0000-0002-9337-329X","observed_orcids":["https://orcid.org/0000-0002-9337-329X"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Subramanyam N Murthy","raw_affiliation_strings":["Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108535774","display_name":"Philip J. Kadowitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip J Kadowitz","raw_affiliation_strings":["Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA","institution_ids":["https://openalex.org/I114832834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I114832834"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"15","issue":"2","first_page":"25","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":1.0},{"id":"https://openalex.org/keywords/nitric-oxide-synthase","display_name":"nitric oxide synthase","score":0.9800000190734863},{"id":"https://openalex.org/keywords/plant-development","display_name":"plant development","score":0.7519999742507935},{"id":"https://openalex.org/keywords/bacterial-signaling","display_name":"bacterial signaling","score":0.824999988079071},{"id":"https://openalex.org/keywords/biofilm-formation","display_name":"biofilm formation","score":0.8529999852180481},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.47600001096725464},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.8379999995231628},{"id":"https://openalex.org/keywords/antibacterial-defense","display_name":"antibacterial defense","score":0.652999997138977},{"id":"https://openalex.org/keywords/antifungal-defense","display_name":"antifungal defense","score":0.7360000014305115},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.8669999837875366},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6809999942779541},{"id":"https://openalex.org/keywords/nf-kappab","display_name":"NF-\u03baB","score":0.9409999847412109},{"id":"https://openalex.org/keywords/chemokines","display_name":"chemokines","score":0.9520000219345093},{"id":"https://openalex.org/keywords/erectile-function","display_name":"erectile function","score":0.7329999804496765},{"id":"https://openalex.org/keywords/endothelium","display_name":"endothelium","score":0.7419999837875366},{"id":"https://openalex.org/keywords/concentration-response-relationship","display_name":"concentration-dependent effects","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.8180186748504639},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6082836985588074},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5784451365470886},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.5388102531433105},{"id":"https://openalex.org/C2779525624","wikidata":"https://www.wikidata.org/wiki/Q225595","display_name":"Reactive nitrogen species","level":3,"score":0.5277417302131653},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.5060729384422302},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4965534806251526},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.46983572840690613},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4667195677757263},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4503081738948822},{"id":"https://openalex.org/C150555746","wikidata":"https://www.wikidata.org/wiki/Q210973","display_name":"Cell signaling","level":3,"score":0.43889838457107544},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3948588967323303},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.38624879717826843},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2539130449295044},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.23900020122528076},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmid:24563585","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24563585","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current topics in pharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2912281","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3930063","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3930063","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3930063/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Top Pharmacol","raw_type":"Text"},{"id":"mag:116571673","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24563585","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2912281","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3930063","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.428600013256073,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8016334885","display_name":"Stem Cell Therapy for Pulmonary Hypertension","funder_award_id":"R01HL077421","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G933344806","display_name":"CARDIOPULMONARY SURGERY RESEARCH","funder_award_id":"R01HL062000","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":95,"referenced_works":["https://openalex.org/W92508582","https://openalex.org/W122947453","https://openalex.org/W324849662","https://openalex.org/W1209101840","https://openalex.org/W1540820582","https://openalex.org/W1560571961","https://openalex.org/W1575028964","https://openalex.org/W1578257252","https://openalex.org/W1594103979","https://openalex.org/W1611522350","https://openalex.org/W1668019941","https://openalex.org/W1767563188","https://openalex.org/W1834041853","https://openalex.org/W1929009802","https://openalex.org/W1971377175","https://openalex.org/W1973568422","https://openalex.org/W1974930528","https://openalex.org/W1975404934","https://openalex.org/W1976501995","https://openalex.org/W1979521526","https://openalex.org/W1980414703","https://openalex.org/W1981450269","https://openalex.org/W1981930263","https://openalex.org/W1985404699","https://openalex.org/W1991251241","https://openalex.org/W1992179114","https://openalex.org/W1992622442","https://openalex.org/W1993675898","https://openalex.org/W1995384886","https://openalex.org/W1999446384","https://openalex.org/W2000397914","https://openalex.org/W2004107049","https://openalex.org/W2005279808","https://openalex.org/W2005355701","https://openalex.org/W2006124330","https://openalex.org/W2006157804","https://openalex.org/W2007737411","https://openalex.org/W2011237115","https://openalex.org/W2014592293","https://openalex.org/W2015609014","https://openalex.org/W2017973394","https://openalex.org/W2019341050","https://openalex.org/W2019756176","https://openalex.org/W2020840491","https://openalex.org/W2022870221","https://openalex.org/W2022901952","https://openalex.org/W2023633834","https://openalex.org/W2027511000","https://openalex.org/W2028971791","https://openalex.org/W2029187140","https://openalex.org/W2032512655","https://openalex.org/W2036610884","https://openalex.org/W2036929381","https://openalex.org/W2039406268","https://openalex.org/W2041753238","https://openalex.org/W2045106503","https://openalex.org/W2050712851","https://openalex.org/W2054665982","https://openalex.org/W2055566263","https://openalex.org/W2056147576","https://openalex.org/W2057528407","https://openalex.org/W2064971822","https://openalex.org/W2065237831","https://openalex.org/W2066415138","https://openalex.org/W2066515050","https://openalex.org/W2066983605","https://openalex.org/W2069682170","https://openalex.org/W2070696792","https://openalex.org/W2073132923","https://openalex.org/W2073672111","https://openalex.org/W2073879336","https://openalex.org/W2074100616","https://openalex.org/W2078209051","https://openalex.org/W2080089077","https://openalex.org/W2082233445","https://openalex.org/W2092145002","https://openalex.org/W2092170556","https://openalex.org/W2096049206","https://openalex.org/W2096703116","https://openalex.org/W2108173186","https://openalex.org/W2109793046","https://openalex.org/W2112896586","https://openalex.org/W2121358285","https://openalex.org/W2126009455","https://openalex.org/W2126033809","https://openalex.org/W2128888406","https://openalex.org/W2134496735","https://openalex.org/W2134727832","https://openalex.org/W2136798531","https://openalex.org/W2140099748","https://openalex.org/W2147049445","https://openalex.org/W2149200346","https://openalex.org/W2156455541","https://openalex.org/W2164189667","https://openalex.org/W2173833672"],"related_works":["https://openalex.org/W2356237841","https://openalex.org/W2017552942","https://openalex.org/W2970622044","https://openalex.org/W2351506304","https://openalex.org/W2073707289","https://openalex.org/W3126787810","https://openalex.org/W1530985889","https://openalex.org/W1606755075","https://openalex.org/W150745346","https://openalex.org/W4283321696"],"abstract_inverted_index":{"Since":[0],"its":[1],"discovery,":[2],"nitric":[3,53],"oxide":[4,54],"(NO)":[5],"has":[6,115],"been":[7],"observed":[8],"to":[9,73,148,170,219,228],"play":[10],"an":[11,204],"important":[12],"role":[13],"in":[14,35,63,118,153,214,217],"the":[15,31,79,100,119,122,154,201,215],"physiology":[16],"of":[17,33,46,87,139,156,178,187],"single-celled":[18],"organisms":[19],"as":[20,22],"well":[21],"high-order":[23],"vertebrates.":[24],"In":[25,83],"this":[26],"review,":[27],"we":[28],"will":[29],"discuss":[30],"involvement":[32],"NO":[34,41,60,72,88,98,114,123,129,149,171,208],"bacterial,":[36,49],"plant":[37,90],"and":[38,51,67,99,110,127,136,159,196,223],"human":[39],"systems.":[40],"originates":[42],"from":[43],"a":[44,133,185],"variety":[45],"sources,":[47],"namely":[48],"plant,":[50],"mammalian":[52],"synthases":[55],"which":[56,161,226],"oxidize":[57],"L-arginine.":[58],"Bacterial":[59],"is":[61,125,150,172,209],"involved":[62],"toxin":[64],"synthesis,":[65],"signaling":[66,189],"biofilm":[68],"formation.":[69],"Organisms":[70],"use":[71],"mediate":[74],"oxidative":[75],"stress":[76],"incurred":[77],"during":[78],"innate":[80],"immune":[81,120],"response.":[82,206],"plants,":[84],"large":[85],"amounts":[86],"hinder":[89],"growth,":[91],"while":[92],"lower":[93],"concentrations":[94],"regulate":[95],"normal":[96],"development.":[97],"associated":[101],"reactive":[102],"oxygen":[103],"species":[104],"(ROS)":[105],"are":[106],"effective":[107],"antibacterial,":[108],"anti-parasitic,":[109],"antifungal":[111],"agents.":[112],"Though":[113],"therapeutic":[116],"effects":[117],"system,":[121],"response":[124,147,169,218],"biphasic":[126,146],"concentration-dependent.":[128],"promotes":[130],"tumorigenesis":[131],"within":[132],"concentration":[134,173],"range,":[135],"induces":[137],"apoptosis":[138],"cancerous":[140],"cells":[141],"at":[142],"other":[143],"concentrations.":[144],"The":[145,167],"also":[151],"evident":[152],"regulation":[155],"chemokine,":[157],"interleukins,":[158],"NF-\u03baB,":[160],"can":[162],"promote":[163],"or":[164],"inhibit":[165],"inflammation.":[166],"physiologic":[168],"dependent.":[174],"NO,":[175],"by":[176],"way":[177],"non-adrenergic":[179],"noncholinergic":[180],"(NANC)":[181],"nerve":[182,221],"transmission,":[183],"propagates":[184],"cascade":[186],"molecular":[188],"that":[190],"facilitates":[191],"smooth":[192],"muscle":[193],"cell":[194],"relaxation":[195],"increased":[197],"arterial":[198],"inflow":[199],"into":[200],"corpora,":[202],"initiating":[203],"erectile":[205],"Additional":[207],"released":[210],"through":[211],"NOS":[212],"activity":[213,222],"endothelium":[216],"cholinergic":[220],"shear":[224],"stress,":[225],"helps":[227],"maintain":[229],"erection.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}