{"id":"https://openalex.org/W115901917","doi":"https://doi.org/10.1123/ijsnem.18.2.142","title":"Effects of Creatine Loading on Electromyographic Fatigue Threshold in Cycle Ergometry in College-Age Men","display_name":"Effects of Creatine Loading on Electromyographic Fatigue Threshold in Cycle Ergometry in College-Age Men","publication_year":2008,"publication_date":"2008-04-01","ids":{"openalex":"https://openalex.org/W115901917","doi":"https://doi.org/10.1123/ijsnem.18.2.142","mag":"115901917","pmid":"https://pubmed.ncbi.nlm.nih.gov/18458358"},"language":"en","primary_location":{"id":"doi:10.1123/ijsnem.18.2.142","doi":"https://doi.org/10.1123/ijsnem.18.2.142","is_oa":false,"landing_page_url":"https://doi.org/10.1123/ijsnem.18.2.142","pdf_url":null,"source":{"id":"https://openalex.org/S54215592","display_name":"International Journal of Sport Nutrition and Exercise Metabolism","issn_l":"1526-484X","issn":["1526-484X","1543-2742"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310322142","host_organization_name":"Human Kinetics","host_organization_lineage":["https://openalex.org/P4310322142"],"host_organization_lineage_names":["Human Kinetics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Sport Nutrition and Exercise Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103791647","display_name":"Ashley A. Walter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashley A. Walter","raw_affiliation_strings":["Department of Health and Exercise Science, University of Oklahoma, Norman, OK, USA","University of Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health and Exercise Science, University of Oklahoma, Norman, OK, USA","institution_ids":["https://openalex.org/I8692664"]},{"raw_affiliation_string":"University of Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046014997","display_name":"Abbie E. Smith\u2010Ryan","orcid":"https://orcid.org/0000-0002-5405-304X","observed_orcids":["https://orcid.org/0000-0002-5405-304X"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abbie E. Smith","raw_affiliation_strings":["University of Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053216088","display_name":"Trent J. Herda","orcid":"https://orcid.org/0000-0002-5555-5156","observed_orcids":["https://orcid.org/0000-0002-5555-5156"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trent J. Herda","raw_affiliation_strings":["University of Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091598235","display_name":"Eric D. Ryan","orcid":"https://orcid.org/0000-0001-9589-4534","observed_orcids":["https://orcid.org/0000-0001-9589-4534"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric D. Ryan","raw_affiliation_strings":["University of Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109195963","display_name":"Jordan Robert Moon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jordan R. Moon","raw_affiliation_strings":["University of Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025919991","display_name":"Joel T. Cramer","orcid":"https://orcid.org/0000-0002-5270-9359","observed_orcids":["https://orcid.org/0000-0002-5270-9359"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel T. Cramer","raw_affiliation_strings":["University of Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050388027","display_name":"Jeffrey R. Stout","orcid":"https://orcid.org/0000-0001-6114-1649","observed_orcids":["https://orcid.org/0000-0001-6114-1649"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey R. Stout","raw_affiliation_strings":["University of Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I8692664"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.01531967,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"18","issue":"2","first_page":"142","last_page":"151"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10157","display_name":"Sports Performance and Training","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10784","display_name":"Muscle activation and electromyography studies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/creatine-loading","display_name":"creatine loading","score":0.8349999785423279},{"id":"https://openalex.org/keywords/creatine-supplementation","display_name":"creatine supplementation","score":0.8820000290870667},{"id":"https://openalex.org/keywords/muscle-fatigue","display_name":"muscle fatigue","score":0.7110000252723694},{"id":"https://openalex.org/keywords/cycle-ergometry","display_name":"cycle ergometry","score":0.8529999852180481},{"id":"https://openalex.org/keywords/vastus-lateralis","display_name":"vastus lateralis","score":0.972000002861023},{"id":"https://openalex.org/keywords/placebo-effect","display_name":"placebo effect","score":0.41600000858306885},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C2779896295","wikidata":"https://www.wikidata.org/wiki/Q223600","display_name":"Creatine","level":2,"score":0.668787956237793},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6631804704666138},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5465025305747986},{"id":"https://openalex.org/C2777515770","wikidata":"https://www.wikidata.org/wiki/Q507369","display_name":"Electromyography","level":2,"score":0.48341429233551025},{"id":"https://openalex.org/C43893838","wikidata":"https://www.wikidata.org/wiki/Q840545","display_name":"Sports medicine","level":2,"score":0.4398883283138275},{"id":"https://openalex.org/C2776874296","wikidata":"https://www.wikidata.org/wiki/Q6940317","display_name":"Muscle fatigue","level":3,"score":0.43386316299438477},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4227031469345093},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36278751492500305},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3501678705215454}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001642","descriptor_name":"Bicycling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003401","descriptor_name":"Creatine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004576","descriptor_name":"Electromyography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010807","descriptor_name":"Physical Endurance","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010807","descriptor_name":"Physical Endurance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013647","descriptor_name":"Task Performance and Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018763","descriptor_name":"Muscle Fatigue","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018763","descriptor_name":"Muscle Fatigue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1123/ijsnem.18.2.142","doi":"https://doi.org/10.1123/ijsnem.18.2.142","is_oa":false,"landing_page_url":"https://doi.org/10.1123/ijsnem.18.2.142","pdf_url":null,"source":{"id":"https://openalex.org/S54215592","display_name":"International Journal of Sport Nutrition and Exercise Metabolism","issn_l":"1526-484X","issn":["1526-484X","1543-2742"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310322142","host_organization_name":"Human Kinetics","host_organization_lineage":["https://openalex.org/P4310322142"],"host_organization_lineage_names":["Human Kinetics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Sport Nutrition and Exercise Metabolism","raw_type":"journal-article"},{"id":"pmid:18458358","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18458358","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of sport nutrition and exercise metabolism","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W1521478705","https://openalex.org/W1546129375","https://openalex.org/W1554940439","https://openalex.org/W1570988358","https://openalex.org/W1573193689","https://openalex.org/W1762661743","https://openalex.org/W1810560969","https://openalex.org/W1880822625","https://openalex.org/W1940483143","https://openalex.org/W1962568506","https://openalex.org/W1964720379","https://openalex.org/W1971696658","https://openalex.org/W1973031101","https://openalex.org/W1975433786","https://openalex.org/W1985384589","https://openalex.org/W1991913871","https://openalex.org/W1995129323","https://openalex.org/W2002407634","https://openalex.org/W2005370586","https://openalex.org/W2007786861","https://openalex.org/W2010580264","https://openalex.org/W2014323306","https://openalex.org/W2015154405","https://openalex.org/W2016366492","https://openalex.org/W2017129538","https://openalex.org/W2019467471","https://openalex.org/W2025772491","https://openalex.org/W2028436089","https://openalex.org/W2030282308","https://openalex.org/W2051040956","https://openalex.org/W2059464152","https://openalex.org/W2060249029","https://openalex.org/W2073219514","https://openalex.org/W2073238594","https://openalex.org/W2084405775","https://openalex.org/W2084821630","https://openalex.org/W2086206562","https://openalex.org/W2098500937","https://openalex.org/W2100578094","https://openalex.org/W2113689204","https://openalex.org/W2113806307","https://openalex.org/W2118449816","https://openalex.org/W2129961360","https://openalex.org/W2151030494","https://openalex.org/W2153371250","https://openalex.org/W2158705184","https://openalex.org/W2159929798","https://openalex.org/W2164476255","https://openalex.org/W2170928888","https://openalex.org/W2176120039","https://openalex.org/W2209420503","https://openalex.org/W2216177017","https://openalex.org/W2315138737","https://openalex.org/W2415827509","https://openalex.org/W2438944616","https://openalex.org/W2922541706"],"related_works":["https://openalex.org/W2159476091","https://openalex.org/W1978150106","https://openalex.org/W2153371250","https://openalex.org/W2808049887","https://openalex.org/W2022959210","https://openalex.org/W2082869550","https://openalex.org/W2014367835","https://openalex.org/W2744892970","https://openalex.org/W2060141758","https://openalex.org/W2512877839"],"abstract_inverted_index":{"The":[0,169],"purpose":[1],"of":[2,10,13,62,80,130,165,244],"this":[3,49,254],"study":[4,51],"was":[5,148,172,229,240],"to":[6,116,141,152,160,191],"examine":[7],"the":[8,18,127,131,155,232,251],"effects":[9],"5":[11,102],"d":[12],"creatine":[14],"(Cr)":[15],"loading":[16,89,246],"on":[17,126,247],"electromyographic":[19],"fatigue":[20],"threshold":[21],"(EMG":[22],"FT)":[23],"in":[24,48,208,227,231,253],"college-age":[25],"men.":[26],"Sixteen":[27],"men":[28],"(age":[29],"22.4":[30],"+/-":[31,36,41,45],"2.6":[32],"yr,":[33],"height":[34],"177.4":[35],"6.8":[37],"cm,":[38],"weight":[39,228],"79.5":[40],"10.6":[42],"kg;":[43],"M":[44],"SD)":[46],"participated":[47],"double-blind":[50],"and":[52,106,217],"were":[53,144,189],"randomly":[54],"placed":[55,125],"into":[56],"either":[57],"placebo":[58],"(Pl;":[59],"10":[60,78,163],"g":[61,74,79],"flavored":[63,81],"fructose":[64,82],"powder":[65,83],"per":[66,84],"packet;":[67,85],"n":[68,86],"=":[69,87,225],"8)":[70,88],"or":[71],"Cr":[72,233,245],"(5":[73],"dicreatine":[75],"citrate":[76],"plus":[77],"groups.":[90],"Each":[91],"participant":[92,110],"ingested":[93],"1":[94],"packet":[95],"4":[96],"times/d,":[97],"totaling":[98],"20":[99],"g/d":[100],"for":[101,154,177,215,250],"days":[103],"(loading).":[104],"Before":[105],"after":[107],"loading,":[108],"each":[109,178,185],"performed":[111],"a":[112,209,221,241],"discontinuous":[113],"cycle-ergometer":[114],"test":[115],"determine":[117],"his":[118],"EMG":[119,170,193,248],"FT,":[120],"using":[121],"bipolar":[122],"surface":[123],"electrodes":[124],"vastus":[128],"lateralis":[129],"right":[132],"thigh.":[133],"Four":[134],"60-s":[135,179],"work":[136,180,187],"bouts":[137,151],"(ranging":[138],"from":[139,184],"200":[140],"400":[142],"W)":[143],"completed.":[145],"Adequate":[146],"rest":[147],"given":[149],"between":[150],"allow":[153],"participants'":[156],"heart":[157],"rate":[158],"(HR)":[159],"drop":[161],"within":[162],"beats":[164],"their":[166],"resting":[167],"HR.":[168],"amplitude":[171],"averaged":[173],"over":[174],"5-s":[175],"intervals":[176],"bout.":[181],"Resulting":[182],"slopes":[183],"successive":[186],"bout":[188],"used":[190],"calculate":[192],"FT.":[194],"A":[195],"2-way":[196],"ANOVA,":[197],"Group":[198],"(Cr":[199],"vs.":[200,205],"Pl)":[201],"x":[202],"Time":[203],"(pre":[204],"post),":[206],"resulted":[207],"nonsignificant":[210],"(p":[211,224],">":[212],".05)":[213],"interaction":[214],"supplement":[216],"time.":[218],"In":[219],"addition,":[220],"significant":[222],"increase":[223],".009)":[226],"observed":[230],"group.":[234],"These":[235],"data":[236],"suggest":[237],"that":[238],"there":[239],"minimal":[242],"influence":[243],"FT":[249],"participants":[252],"study.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}