{"id":"https://openalex.org/W115348553","doi":null,"title":"Sensitization of guinea-pigs to measles vaccines.","display_name":"Sensitization of guinea-pigs to measles vaccines.","publication_year":1969,"publication_date":"1969-11-01","ids":{"openalex":"https://openalex.org/W115348553","mag":"115348553","pmid":"https://pubmed.ncbi.nlm.nih.gov/4982816","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1579140"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1579140","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1579140","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1579140","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113581340","display_name":"MARIE A. APRILE","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M A Aprile","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035928234","display_name":"D. Kadar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Kadar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5050379884","display_name":"S. Wilson","orcid":"https://orcid.org/0000-0002-0814-301X","observed_orcids":["https://orcid.org/0000-0002-0814-301X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Wilson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0204,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.78760674,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"5","first_page":"531","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/measles-vaccine","display_name":"measles vaccine","score":0.9150000214576721},{"id":"https://openalex.org/keywords/guinea-pig","display_name":"guinea pig","score":0.7519999742507935},{"id":"https://openalex.org/keywords/attenuated-measles-virus","display_name":"attenuated measles virus","score":0.8460000157356262},{"id":"https://openalex.org/keywords/inactivated-measles-vaccine","display_name":"inactivated measles vaccine","score":0.8989999890327454},{"id":"https://openalex.org/keywords/chick-embryo-tissue-culture","display_name":"chick embryo tissue culture","score":0.746999979019165},{"id":"https://openalex.org/keywords/monkey-kidney-tissue-culture","display_name":"monkey kidney tissue culture","score":0.9890000224113464},{"id":"https://openalex.org/keywords/adjuvants","display_name":"adjuvants","score":0.765999972820282},{"id":"https://openalex.org/keywords/tween-80","display_name":"Tween 80","score":0.8059999942779541},{"id":"https://openalex.org/keywords/ether-treatment","display_name":"ether treatment","score":0.5809999704360962},{"id":"https://openalex.org/keywords/tissue-culture-fluid","display_name":"tissue culture fluid","score":0.4860000014305115},{"id":"https://openalex.org/keywords/schultz-dale-reaction","display_name":"Schultz-Dale reaction","score":0.7260000109672546},{"id":"https://openalex.org/keywords/passive-cutaneous-anaphylaxis","display_name":"passive cutaneous anaphylaxis","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C2776438120","wikidata":"https://www.wikidata.org/wiki/Q79793","display_name":"Measles","level":3,"score":0.7747917771339417},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6892876029014587},{"id":"https://openalex.org/C2778199166","wikidata":"https://www.wikidata.org/wiki/Q573943","display_name":"Measles virus","level":4,"score":0.671230673789978},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5474399924278259},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5342653393745422},{"id":"https://openalex.org/C2776217527","wikidata":"https://www.wikidata.org/wiki/Q944828","display_name":"Sensitization","level":2,"score":0.5206910371780396},{"id":"https://openalex.org/C90703135","wikidata":"https://www.wikidata.org/wiki/Q3287622","display_name":"Tissue culture","level":3,"score":0.5131645798683167},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5108744502067566},{"id":"https://openalex.org/C2778815084","wikidata":"https://www.wikidata.org/wiki/Q79803","display_name":"Guinea pig","level":2,"score":0.5027003288269043},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.4967249035835266},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.2339710295200348},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.11923754215240479},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000276","descriptor_name":"Adjuvants, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000882","descriptor_name":"Haplorhini","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002642","descriptor_name":"Chick Embryo","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005019","descriptor_name":"Ethyl Ethers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008458","descriptor_name":"Measles Vaccine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008459","descriptor_name":"Measles virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010323","descriptor_name":"Passive Cutaneous Anaphylaxis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012698","descriptor_name":"Serologic Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013501","descriptor_name":"Surface-Active Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046508","descriptor_name":"Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:1579140","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1579140","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},{"id":"pmid:4982816","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4982816","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental immunology","raw_type":"Journal Article"},{"id":"mag:115348553","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4982816","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1579140","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1579140","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1546412281","https://openalex.org/W2028543254","https://openalex.org/W2038571884","https://openalex.org/W2039431525","https://openalex.org/W2043188942","https://openalex.org/W2044885197","https://openalex.org/W2047330128","https://openalex.org/W2057075520","https://openalex.org/W2084740336","https://openalex.org/W2125080051","https://openalex.org/W2241546110"],"related_works":["https://openalex.org/W2038571884","https://openalex.org/W2402097896","https://openalex.org/W2397430773","https://openalex.org/W222362522","https://openalex.org/W2119644174","https://openalex.org/W1964663192","https://openalex.org/W1760838182","https://openalex.org/W1986400437","https://openalex.org/W4313376353","https://openalex.org/W6888430137"],"abstract_inverted_index":{"Attenuated":[0],"measles":[1,13,71],"virus":[2,72],"vaccine":[3],"of":[4,26,40,68,79],"chick":[5,45],"embryo":[6,46],"tissue":[7,19,47,77],"culture":[8,20,48],"origin":[9],"and":[10,44,74,82],"unadsorbed":[11],"inactivated":[12],"vaccines":[14,39],"derived":[15],"from":[16],"monkey":[17,42],"kidney":[18,43],"produced":[21],"little":[22],"or":[23,33],"no":[24],"sensitization":[25],"guinea-pigs,":[27],"as":[28],"monitored":[29],"by":[30],"the":[31,65],"Schultz\u2013Dale":[32],"passive":[34],"cutaneous":[35],"anaphylaxis":[36],"techniques.":[37],"Inactivated":[38],"both":[41],"origins":[49],"were":[50],"sensitizing":[51,59],"when":[52],"they":[53],"contained":[54],"a":[55],"mineral":[56],"adjuvant.":[57],"The":[58],"activity":[60],"was":[61],"also":[62],"present":[63],"in":[64,75],"aqueous":[66],"phase":[67],"Tween":[69],"80\u2013ether-treated":[70],"fluid":[73],"uninfected":[76],"cultures":[78],"simian,":[80],"avian":[81],"human":[83],"origins.":[84]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}