{"id":"https://openalex.org/W114352986","doi":"https://doi.org/10.1097/00007611-196305000-00015","title":"Hodgkin\u02bcs Disease Following Administration of Thorotrast","display_name":"Hodgkin\u02bcs Disease Following Administration of Thorotrast","publication_year":1963,"publication_date":"1963-05-01","ids":{"openalex":"https://openalex.org/W114352986","doi":"https://doi.org/10.1097/00007611-196305000-00015","mag":"114352986","pmid":"https://pubmed.ncbi.nlm.nih.gov/13996840"},"language":"en","primary_location":{"id":"doi:10.1097/00007611-196305000-00015","doi":"https://doi.org/10.1097/00007611-196305000-00015","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007611-196305000-00015","pdf_url":null,"source":{"id":"https://openalex.org/S89143414","display_name":"Southern Medical Journal","issn_l":"0038-4348","issn":["0038-4348","1541-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042301604","display_name":"John V. Verner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JOHN V. VERNER","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5064121083","display_name":"ALBERT G. SMITH","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ALBERT G. SMITH","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1435,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.78196756,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"56","issue":"5","first_page":"524","last_page":"528"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.40720000863075256,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.40720000863075256,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.26899999380111694,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.17579999566078186,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hodgkin-lymphoma","display_name":"Hodgkin's disease","score":0.9819999933242798},{"id":"https://openalex.org/keywords/thorotrast","display_name":"thorotrast","score":0.8880000114440918},{"id":"https://openalex.org/keywords/thorium-dioxide","display_name":"thorium dioxide","score":0.9779999852180481},{"id":"https://openalex.org/keywords/thorium","display_name":"thorium","score":0.3779999911785126},{"id":"https://openalex.org/keywords/radiation-induced-cancer","display_name":"radiation-induced cancer","score":0.7789999842643738},{"id":"https://openalex.org/keywords/reticuloendothelial-system","display_name":"reticuloendothelial system","score":0.7459999918937683},{"id":"https://openalex.org/keywords/reed-sternberg-cells","display_name":"Reed-Sternberg cells","score":0.9319999814033508},{"id":"https://openalex.org/keywords/pleomorphic-cells","display_name":"pleomorphic cells","score":0.6710000038146973},{"id":"https://openalex.org/keywords/cholangiocarcinoma","display_name":"cholangiocarcinoma","score":0.765999972820282},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.35600000619888306},{"id":"https://openalex.org/keywords/spleen","display_name":"spleen","score":0.9950000047683716},{"id":"https://openalex.org/keywords/lymph-nodes","display_name":"lymph nodes","score":0.8830000162124634}],"concepts":[{"id":"https://openalex.org/C2780353417","wikidata":"https://www.wikidata.org/wiki/Q423827","display_name":"Thorotrast","level":2,"score":0.976963460445404},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9675170183181763},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.547480583190918},{"id":"https://openalex.org/C2780765947","wikidata":"https://www.wikidata.org/wiki/Q12033531","display_name":"Administration (probate law)","level":2,"score":0.5202696919441223},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.286720871925354},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007680","descriptor_name":"Kidney Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011172","descriptor_name":"Portography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013160","descriptor_name":"Splenic Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013910","descriptor_name":"Thorium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013911","descriptor_name":"Thorium Dioxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/00007611-196305000-00015","doi":"https://doi.org/10.1097/00007611-196305000-00015","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007611-196305000-00015","pdf_url":null,"source":{"id":"https://openalex.org/S89143414","display_name":"Southern Medical Journal","issn_l":"0038-4348","issn":["0038-4348","1541-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern Medical Journal","raw_type":"journal-article"},{"id":"pmid:13996840","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13996840","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern medical journal","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1494576183","https://openalex.org/W13500388","https://openalex.org/W8698012","https://openalex.org/W2091063321","https://openalex.org/W2473101266","https://openalex.org/W2066219227","https://openalex.org/W1965451720","https://openalex.org/W2463747586","https://openalex.org/W2398628052","https://openalex.org/W2169137775"],"abstract_inverted_index":{"A":[0,214],"case":[1],"of":[2,10,20,27,33,73,85,102,120,133,160,163,168,178,187,198,234,239],"Hodgkin's":[3],"disease":[4,22,200],"developing":[5],"12":[6],"yr":[7],"following":[8],"administration":[9],"ThO/sub":[11,54,67,106,188],"2/":[12,68,107,189],"is":[13,216,242,246],"reported,":[14],"representing":[15,47],"the":[16,28,34,44,59,112,117,121,138,169,182,196,204,230],"only":[17],"known":[18],"example":[19],"this":[21],"associated":[23,223],"with":[24,53,83,201,224],"Th.":[25,213],"Radiography":[26],"abdomen":[29,45],"showed":[30],"increased":[31],"density":[32],"liver":[35,60,170],"and":[36,61,76,79,89,124,140,150,206],"spleen,":[37,123],"as":[38,40,115,252],"well":[39],"radiopaque":[41],"densities":[42,57],"in":[43,58,116,137,155,171,181,229,236],"presumably":[46],"nodes":[48],"which":[49],"were":[50,63,96,135,159],"heavily":[51],"infiltrated":[52],"2/.":[55,105],"The":[56,70,176],"spleen":[62,139],"also":[64,109],"ascribable":[65],"to":[66,100,147,203,249],"deposits.":[69],"tumor":[71,151,179],"consisted":[72],"pleomorphic":[74],"round":[75],"polyhedral":[77],"cells":[78,119,180],"Reed-Sternberg":[80],"cells,":[81],"along":[82],"areas":[84,158],"fibrosis,":[86],"necrosis,":[87],"hemorrhage,":[88],"mononuclear":[90],"cell":[91],"reaction.":[92],"Pleomorphic":[93],"cellular":[94],"changes":[95],"frequentiy":[97],"found":[98,110,228],"adjacent":[99],"deposits":[101],"ThO/":[103],"sub":[104],"was":[108],"throughout":[111],"reticuloendothelial":[113,183],"system,":[114],"reticulum":[118],"liver,":[122],"lymph":[125],"nodes.":[126],"Using":[127],"a":[128,253],"gas-flow":[129],"counter,":[130],"significant":[131],"counts":[132],"radiation":[134],"detected":[136],"periaortic":[141],"lymphoid":[142],"tissues,":[143],"sites":[144,220],"histologically":[145],"demonstrated":[146],"contain":[148],"Th":[149,192],"Proliferated":[152],"bile":[153,165],"ducts":[154],"hepatic":[156],"portal":[157],"interest":[161],"because":[162],"reported":[164],"duct":[166],"carcinoma":[167],"patients":[172],"previously":[173],"receiving":[174],"Thorotrast.":[175],"presence":[177],"system":[184],"surrounding":[185],"granules":[186],"suggests":[190],"that":[191,244],"induced":[193],"or":[194,211],"inttiated":[195],"development":[197],"Hodgkin'smore\u00a0\u00bb":[199],"spread":[202],"kidneys":[205],"other":[207],"organs":[208],"containirg":[209],"little":[210],"no":[212],"table":[215],"given":[217],"listing":[218],"anatomic":[219],"where":[221],"tumors":[222,235],"Thorotrast":[225,251],"have":[226],"been":[227],"commonly":[231],"recognized":[232],"types":[233],"rough":[237],"order":[238],"incidence.":[240],"It":[241],"suggested":[243],"there":[245],"ample":[247],"evidence":[248],"incriminate":[250],"definite":[254],"oncogenic":[255],"agent.":[256],"(H.H.D.)\u00ab\u00a0less":[257]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}