{"id":"https://openalex.org/W113900619","doi":null,"title":"Exogenous Melatonin: Its Relationship to Prolactin and Its Efficacy at Reducing or Alleviating Stress.","display_name":"Exogenous Melatonin: Its Relationship to Prolactin and Its Efficacy at Reducing or Alleviating Stress.","publication_year":1998,"publication_date":"1998-09-01","ids":{"openalex":"https://openalex.org/W113900619","mag":"113900619"},"language":"en","primary_location":{"id":"mag:113900619","doi":null,"is_oa":false,"landing_page_url":"https://apps.dtic.mil/dtic/tr/fulltext/u2/a356135.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019853761","display_name":"Albert W. Kirby","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Albert W. Kirby","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044084833","display_name":"Carlos A. Comperatore","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlos A. Comperatore","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018871900","display_name":"Pik Rivera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pik Rivera","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Santiago Arroyo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Santiago Arroyo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065384808","display_name":"Regina Bay-Wright","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Regina Bay-Wright","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00810081,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exogenous-melatonin","display_name":"exogenous melatonin","score":0.9700000286102295},{"id":"https://openalex.org/keywords/prolactin","display_name":"prolactin","score":0.9449999928474426},{"id":"https://openalex.org/keywords/stress-reduction","display_name":"stress reduction","score":0.7070000171661377},{"id":"https://openalex.org/keywords/premenstrual-syndrome","display_name":"premenstrual syndrome","score":0.8420000076293945},{"id":"https://openalex.org/keywords/menstrual-cycle","display_name":"menstrual cycle","score":0.7829999923706055},{"id":"https://openalex.org/keywords/time-zone-change","display_name":"time zone change","score":0.5989999771118164},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.6539999842643738},{"id":"https://openalex.org/keywords/mood","display_name":"mood","score":0.38600000739097595}],"concepts":[{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.9697716236114502},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.9499309062957764},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7054712772369385},{"id":"https://openalex.org/C187785154","wikidata":"https://www.wikidata.org/wiki/Q5464664","display_name":"Follicular phase","level":2,"score":0.6440679430961609},{"id":"https://openalex.org/C143228043","wikidata":"https://www.wikidata.org/wiki/Q2363481","display_name":"Luteal phase","level":3,"score":0.618432343006134},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5835155844688416},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49555981159210205},{"id":"https://openalex.org/C3017583242","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Placebo group","level":4,"score":0.4320318102836609},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4219318628311157},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3265044093132019},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.27270233631134033},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:113900619","doi":null,"is_oa":false,"landing_page_url":"https://apps.dtic.mil/dtic/tr/fulltext/u2/a356135.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W121603428","https://openalex.org/W1536700299","https://openalex.org/W1547975228","https://openalex.org/W1634519075","https://openalex.org/W1642124290","https://openalex.org/W1969735301","https://openalex.org/W1972172524","https://openalex.org/W1990573443","https://openalex.org/W2008059968","https://openalex.org/W2009634330","https://openalex.org/W2016767846","https://openalex.org/W2019148495","https://openalex.org/W2019801298","https://openalex.org/W2022496632","https://openalex.org/W2032572383","https://openalex.org/W2038305850","https://openalex.org/W2047816798","https://openalex.org/W2047884250","https://openalex.org/W2052297185","https://openalex.org/W2052598407","https://openalex.org/W2058232887","https://openalex.org/W2068392981","https://openalex.org/W2092213743","https://openalex.org/W2095279793","https://openalex.org/W2098464612","https://openalex.org/W2124124560","https://openalex.org/W2140473103","https://openalex.org/W2252602892","https://openalex.org/W2287833581","https://openalex.org/W2396108327","https://openalex.org/W2419159684","https://openalex.org/W3217134939"],"related_works":["https://openalex.org/W2002930716","https://openalex.org/W2047884250","https://openalex.org/W1586869006","https://openalex.org/W2008059968","https://openalex.org/W2062804079","https://openalex.org/W2095279793","https://openalex.org/W2098464612","https://openalex.org/W2181826116","https://openalex.org/W2055680100","https://openalex.org/W2947391738"],"abstract_inverted_index":{"Abstract":[0],":":[1],"Recently":[2],"we":[3,49],"completed":[4,144],"a":[5,28,145,169,185,202],"study":[6,68,112],"designed":[7],"to":[8,36,57,78],"investigate":[9],"the":[10,51,59,63,86,94,102,106,111,116,160,175,181,197,209,214],"effect":[11],"of":[12,46,93,110,138,147,155,199],"melatonin":[13,55,139,182,195,206],"administration":[14,108,163,207],"(10":[15],"mg)":[16],"at":[17,172,188],"1300":[18,173],"on":[19,115,153,174],"menstrual":[20,95],"characteristics,":[21],"prolactin,":[22,200],"and":[23,72,89,113,133,140,201,208],"premenstrual":[24],"syndrome-like":[25],"symptoms":[26],"during":[27,85],"simulated":[29,65],"eastward":[30,38],"deployment.":[31,66],"Bright":[32],"lights":[33],"were":[34,127,134],"utilized":[35],"simulate":[37],"movement":[39],"across":[40],"six":[41],"time":[42],"zones.":[43],"During":[44],"analysis":[45,137],"biochemical":[47],"results,":[48],"made":[50],"fortuitous":[52],"discovery":[53],"that":[54,194],"appears":[56],"alleviate":[58],"stress":[60],"associated":[61],"with":[62],"in-house":[64,161],"The":[67,165],"was":[69,76],"double":[70],"blind":[71],"placebo":[73,166],"controlled.":[74],"Melatonin":[75],"given":[77],"healthy":[79],"females":[80],"for":[81,136],"5":[82],"consecutive":[83],"days":[84,157],"late":[87],"follicular":[88],"early":[90],"luteal":[91],"phases":[92],"cycle.":[96],"Volunteers":[97,142],"spent":[98],"24":[99],"hours":[100],"in":[101],"hospital":[103],"before":[104],"entering":[105],"dose":[107,118,162,177],"phase":[109],"again":[114],"last":[117,176],"day.":[119],"On":[120],"those":[121],"2":[122],"days,":[123],"hourly":[124],"blood":[125],"samples":[126],"collected":[128],"from":[129],"an":[130],"in-dwelling":[131],"catheter":[132],"used":[135],"prolactin.":[141],"also":[143],"profile":[146],"moods":[148],"state":[149],"questionnaire":[150],"upon":[151],"waking":[152],"each":[154],"8":[156],"which":[158],"overlapped":[159],"days.":[164],"group":[167,183],"showed":[168,184],"prolactin":[170,186,210],"peak":[171,187,211],"day/blood":[178],"draw,":[179],"while":[180],"1500.":[189],"It":[190],"is":[191,212],"well":[192],"known":[193],"stimulates":[196],"release":[198],"2-hour":[203],"delay":[204],"between":[205],"within":[213],"normal":[215],"expected":[216],"delay.":[217]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}