{"id":"https://openalex.org/W113046439","doi":"https://doi.org/10.1007/978-1-4939-1176-9_6","title":"The Androgen Receptor as a Therapeutic Target for Castration-Resistant Prostate Cancer","display_name":"The Androgen Receptor as a Therapeutic Target for Castration-Resistant Prostate Cancer","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W113046439","doi":"https://doi.org/10.1007/978-1-4939-1176-9_6","mag":"113046439"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4939-1176-9_6","doi":"https://doi.org/10.1007/978-1-4939-1176-9_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4939-1176-9_6","pdf_url":null,"source":{"id":"https://openalex.org/S4210192721","display_name":"Current clinical urology","issn_l":"2197-7194","issn":["2197-7194","2197-7208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Clinical Urology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2476182623","display_name":"Management of Castration Resistant Prostate Cancer"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047583995","display_name":"Jarett L. Feldman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jarett L. Feldman","raw_affiliation_strings":["Department of Medicine, Memorial Sloan Kettering Cancer Center, Genitourinary Oncology Service, 1275 York Avenue, New York, NY, 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Memorial Sloan Kettering Cancer Center, Genitourinary Oncology Service, 1275 York Avenue, New York, NY, 10065, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002358672","display_name":"Dana E. Rathkopf","orcid":"https://orcid.org/0000-0002-4503-7582","observed_orcids":["https://orcid.org/0000-0002-4503-7582"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dana Rathkopf","raw_affiliation_strings":["Department of Medicine, Memorial Sloan Kettering Cancer Center, Genitourinary Oncology Service, 1275 York Avenue, New York, NY, 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Memorial Sloan Kettering Cancer Center, Genitourinary Oncology Service, 1275 York Avenue, New York, NY, 10065, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017288060","display_name":"Michael J. Morris","orcid":"https://orcid.org/0000-0002-9454-0096","observed_orcids":["https://orcid.org/0000-0002-9454-0096"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael J. Morris","raw_affiliation_strings":["Department of Medicine, Memorial Sloan Kettering Cancer Center, Genitourinary Oncology Service, 1275 York Avenue, New York, NY, 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Memorial Sloan Kettering Cancer Center, Genitourinary Oncology Service, 1275 York Avenue, New York, NY, 10065, USA","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5017288060"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05535248,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"77","last_page":"94"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/androgen-receptor","display_name":"androgen receptor","score":1.0},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/enzalutamide","display_name":"enzalutamide","score":0.9620000123977661},{"id":"https://openalex.org/keywords/androgen-receptor-antagonists","display_name":"androgen receptor antagonists","score":0.968999981880188},{"id":"https://openalex.org/keywords/androgen-receptor-signaling","display_name":"androgen receptor signaling","score":0.6639999747276306},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.6690000295639038},{"id":"https://openalex.org/keywords/metastatic-prostate-cancer","display_name":"metastatic prostate cancer","score":0.7900000214576721},{"id":"https://openalex.org/keywords/novel-therapeutic-agents","display_name":"novel therapeutic agents","score":0.6129999756813049},{"id":"https://openalex.org/keywords/clinical-trials","display_name":"clinical trials","score":0.49900001287460327}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.8646012544631958},{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.6815127730369568},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5784651637077332},{"id":"https://openalex.org/C2779256933","wikidata":"https://www.wikidata.org/wiki/Q58929","display_name":"Castration","level":3,"score":0.5583980083465576},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4630894958972931},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4040437340736389},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.24426984786987305},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.07633072137832642}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4939-1176-9_6","doi":"https://doi.org/10.1007/978-1-4939-1176-9_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4939-1176-9_6","pdf_url":null,"source":{"id":"https://openalex.org/S4210192721","display_name":"Current clinical urology","issn_l":"2197-7194","issn":["2197-7194","2197-7208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Clinical Urology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":114,"referenced_works":["https://openalex.org/W122252942","https://openalex.org/W1487307409","https://openalex.org/W1907894188","https://openalex.org/W1934946686","https://openalex.org/W1956906199","https://openalex.org/W1966880264","https://openalex.org/W1973588440","https://openalex.org/W1979897920","https://openalex.org/W1985580668","https://openalex.org/W1995039837","https://openalex.org/W1998668311","https://openalex.org/W1998721649","https://openalex.org/W1998786498","https://openalex.org/W1999343166","https://openalex.org/W2003955264","https://openalex.org/W2008473350","https://openalex.org/W2009402948","https://openalex.org/W2009948262","https://openalex.org/W2012600827","https://openalex.org/W2014476883","https://openalex.org/W2021051883","https://openalex.org/W2022635468","https://openalex.org/W2024432096","https://openalex.org/W2024534768","https://openalex.org/W2026654365","https://openalex.org/W2029054015","https://openalex.org/W2032649515","https://openalex.org/W2034710772","https://openalex.org/W2040997484","https://openalex.org/W2042646980","https://openalex.org/W2048098760","https://openalex.org/W2050551827","https://openalex.org/W2053887709","https://openalex.org/W2057038976","https://openalex.org/W2063956958","https://openalex.org/W2071057846","https://openalex.org/W2073100248","https://openalex.org/W2073374104","https://openalex.org/W2074497307","https://openalex.org/W2077301757","https://openalex.org/W2077438659","https://openalex.org/W2080139523","https://openalex.org/W2080748037","https://openalex.org/W2080761866","https://openalex.org/W2082581177","https://openalex.org/W2084637523","https://openalex.org/W2085847636","https://openalex.org/W2089518544","https://openalex.org/W2092991204","https://openalex.org/W2094269170","https://openalex.org/W2095722179","https://openalex.org/W2095873383","https://openalex.org/W2097084183","https://openalex.org/W2097226696","https://openalex.org/W2097299850","https://openalex.org/W2099367648","https://openalex.org/W2100115202","https://openalex.org/W2100611890","https://openalex.org/W2101127235","https://openalex.org/W2103059478","https://openalex.org/W2104345898","https://openalex.org/W2105129152","https://openalex.org/W2107633226","https://openalex.org/W2108426942","https://openalex.org/W2110841612","https://openalex.org/W2113031878","https://openalex.org/W2113962581","https://openalex.org/W2117296712","https://openalex.org/W2119504728","https://openalex.org/W2119581490","https://openalex.org/W2121312569","https://openalex.org/W2121846636","https://openalex.org/W2123158115","https://openalex.org/W2125069527","https://openalex.org/W2128521034","https://openalex.org/W2130189600","https://openalex.org/W2131931088","https://openalex.org/W2132665968","https://openalex.org/W2134988422","https://openalex.org/W2136294116","https://openalex.org/W2136344158","https://openalex.org/W2138684882","https://openalex.org/W2139920743","https://openalex.org/W2141453591","https://openalex.org/W2141569270","https://openalex.org/W2143329461","https://openalex.org/W2148643283","https://openalex.org/W2148998801","https://openalex.org/W2150447388","https://openalex.org/W2151603894","https://openalex.org/W2151635781","https://openalex.org/W2151922331","https://openalex.org/W2156272715","https://openalex.org/W2157592394","https://openalex.org/W2159448513","https://openalex.org/W2160534562","https://openalex.org/W2165300664","https://openalex.org/W2165782799","https://openalex.org/W2166918329","https://openalex.org/W2167188058","https://openalex.org/W2167331614","https://openalex.org/W2168011358","https://openalex.org/W2169599916","https://openalex.org/W2340799873","https://openalex.org/W2464502417","https://openalex.org/W2515346734","https://openalex.org/W2591124657","https://openalex.org/W2613104851","https://openalex.org/W2617245288","https://openalex.org/W2952807909","https://openalex.org/W2998910881","https://openalex.org/W2999276922","https://openalex.org/W3009012041","https://openalex.org/W4234452258"],"related_works":["https://openalex.org/W2091098941","https://openalex.org/W2891532655","https://openalex.org/W2044287047","https://openalex.org/W2412519912","https://openalex.org/W794048265","https://openalex.org/W2343736576","https://openalex.org/W2028539169","https://openalex.org/W1962442902","https://openalex.org/W1480366037","https://openalex.org/W1563617361"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}