{"id":"https://openalex.org/W112647491","doi":null,"title":"Costs and quality of life in patients with myelodysplastic syndromes.","display_name":"Costs and quality of life in patients with myelodysplastic syndromes.","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W112647491","mag":"112647491","pmid":"https://pubmed.ncbi.nlm.nih.gov/23997987","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3755523"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:2747262","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3755523","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3755523","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006429617","display_name":"Carlo Lucioni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlo Lucioni","raw_affiliation_strings":["Springer Healthcare Italia S.r.l. Milano"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Springer Healthcare Italia S.r.l. Milano","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070851212","display_name":"Carlo Finelli","orcid":"https://orcid.org/0000-0001-9372-1197","observed_orcids":["https://orcid.org/0000-0001-9372-1197"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlo Finelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108371468","display_name":"S. Mazzi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Silvio Mazzi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5084240197","display_name":"Esther N. Oliva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Esther N Oliva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.2392,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.93717033,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"3","issue":"3","first_page":"246","last_page":"59"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12708","display_name":"Economic and Financial Impacts of Cancer","score":0.8227999806404114,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12708","display_name":"Economic and Financial Impacts of Cancer","score":0.8227999806404114,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.07680000364780426,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.06270000338554382,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":1.0},{"id":"https://openalex.org/keywords/health-care-costs","display_name":"health care costs","score":0.8349999785423279},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9829999804496765},{"id":"https://openalex.org/keywords/transfusion-dependence","display_name":"transfusion dependence","score":0.875},{"id":"https://openalex.org/keywords/red-blood-cell-transfusion","display_name":"red blood cell transfusion","score":0.8610000014305115},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.7400000095367432},{"id":"https://openalex.org/keywords/economic-burden","display_name":"economic burden","score":0.40799999237060547}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9344651103019714},{"id":"https://openalex.org/C2780817109","wikidata":"https://www.wikidata.org/wiki/Q954625","display_name":"Myelodysplastic syndromes","level":3,"score":0.8702172040939331},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.7472036480903625},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.447469025850296},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.43597540259361267},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.42783182859420776},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3711804747581482},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3460003137588501},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.13998422026634216},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:2747262","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3755523","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:23997987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23997987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of blood research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3755523","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3755523/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Blood Res","raw_type":"Text"},{"id":"mag:112647491","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23997987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:2741642396","doi":null,"is_oa":false,"landing_page_url":"http://www.ajblood.us/files/ajbr1305004.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2747262","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3755523","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W147324995","https://openalex.org/W187238933","https://openalex.org/W1595046345","https://openalex.org/W1701718929","https://openalex.org/W1832079326","https://openalex.org/W1855038159","https://openalex.org/W1974673911","https://openalex.org/W1979144446","https://openalex.org/W1996092443","https://openalex.org/W2000445173","https://openalex.org/W2000597113","https://openalex.org/W2009620771","https://openalex.org/W2021333892","https://openalex.org/W2022444634","https://openalex.org/W2052822682","https://openalex.org/W2066053804","https://openalex.org/W2076225806","https://openalex.org/W2077411388","https://openalex.org/W2083307780","https://openalex.org/W2091077261","https://openalex.org/W2091771435","https://openalex.org/W2102908631","https://openalex.org/W2117291755","https://openalex.org/W2118771330","https://openalex.org/W2126751948","https://openalex.org/W2149982846","https://openalex.org/W2159931986","https://openalex.org/W2246965407","https://openalex.org/W2255329095","https://openalex.org/W2531186606","https://openalex.org/W2563067310","https://openalex.org/W2577339139","https://openalex.org/W2581859421","https://openalex.org/W2590227580","https://openalex.org/W2599784429"],"related_works":["https://openalex.org/W2741642396","https://openalex.org/W2612494870","https://openalex.org/W1967961601","https://openalex.org/W2590227580","https://openalex.org/W2165758537","https://openalex.org/W2284338374","https://openalex.org/W4405039826","https://openalex.org/W2076225806","https://openalex.org/W2118552577","https://openalex.org/W2009620771"],"abstract_inverted_index":{"Myelodysplastic":[0],"syndromes":[1],"(MDS)":[2],"encompass":[3],"a":[4,11,23],"range":[5,83],"of":[6,48,51,72,148],"myeloid":[7],"neoplasms":[8],"characterised":[9],"by":[10,132],"defect":[12],"in":[13,19,53,101,121],"haematopoietic":[14],"stem":[15],"cell":[16,37],"maturation,":[17],"resulting":[18],"peripheral":[20],"cytopenias.":[21],"As":[22],"major":[24],"consequence,":[25],"most":[26],"MDS":[27],"patients":[28,149,164],"become":[29],"anaemic,":[30],"so":[31],"as":[32],"to":[33,87,98,114,119,126,160],"require":[34],"red":[35],"blood":[36],"transfusions.":[38],"To":[39],"investigate":[40],"the":[41,44,91,102,111,115,122,136,146,166],"costs":[42,80,144],"and":[43,56,66,94,145,165],"impact":[45],"on":[46,135,143],"quality":[47],"life":[49],"(QOL)":[50],"MDS-separately":[52],"transfusion-independent":[54],"(TI)":[55],"-dependent":[57],"(TD)":[58],"patients-a":[59],"literature":[60],"search":[61],"was":[62],"conducted.":[63],"From":[64],"Medline":[65],"Embase,":[67],"742":[68],"studies":[69],"were":[70,75],"identified,":[71],"which":[73],"17":[74],"considered":[76],"eligible.":[77],"Total":[78],"medical":[79],"per":[81],"patient/year":[82],"from":[84,95,110,124],"$":[85,88,96,99],"9,840":[86],"19,811":[89],"for":[90,163],"TI":[92,125],"condition":[93,113,140],"29,608":[97],"51,066":[100],"TD":[103,139],"condition,":[104],"more":[105],"than":[106],"doubling":[107],"when":[108],"moving":[109],"former":[112],"latter.":[116],"With":[117],"regard":[118],"QOL,":[120],"transition":[123],"TD,":[127],"QOL":[128,147],"could":[129],"be":[130],"reduced":[131],"half":[133],"depending":[134],"studies.":[137],"The":[138],"negatively":[141],"impacts":[142],"with":[150],"MDS.":[151],"Therapeutic":[152],"strategies":[153],"that":[154],"reduce":[155],"transfusion":[156],"dependence":[157],"may":[158],"lead":[159],"broad":[161],"benefits":[162],"community.":[167]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}