{"id":"https://openalex.org/W1124157797","doi":null,"title":"Modulation Of Inner Retinal Inhibition With Light Adaptation","display_name":"Modulation Of Inner Retinal Inhibition With Light Adaptation","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1124157797","mag":"1124157797"},"language":"en","primary_location":{"id":"pmh:oai:repository.arizona.edu:10150/565903","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10150/565903","pdf_url":null,"source":{"id":"https://openalex.org/S4306400271","display_name":"UA Campus Repository (The University of Arizona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138006243","host_organization_name":"University of Arizona","host_organization_lineage":["https://openalex.org/I138006243"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080778283","display_name":"Reece E. Mazade","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Reece Mazade","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5080778283"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.7041000127792358,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.7041000127792358,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.18850000202655792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.0908999964594841,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adaptation","display_name":"adaptation","score":0.9950000047683716},{"id":"https://openalex.org/keywords/off-bipolar-cells","display_name":"OFF bipolar cells","score":0.996999979019165},{"id":"https://openalex.org/keywords/glycinergic-inhibition","display_name":"glycinergic inhibition","score":0.8309999704360962},{"id":"https://openalex.org/keywords/gabaergic-inhibition","display_name":"GABAergic inhibition","score":1.0},{"id":"https://openalex.org/keywords/visual-acuity","display_name":"visual acuity","score":0.8339999914169312},{"id":"https://openalex.org/keywords/retinal-signal-processing","display_name":"retinal signal processing","score":0.7379999756813049},{"id":"https://openalex.org/keywords/retinal-adaptation","display_name":"retinal adaptation","score":0.4059999883174896},{"id":"https://openalex.org/keywords/dark-adaptation","display_name":"dark adaptation","score":0.34599998593330383},{"id":"https://openalex.org/keywords/light-adaptation","display_name":"light adaptation","score":0.4180000126361847},{"id":"https://openalex.org/keywords/retinal-interneurons","display_name":"retinal interneurons","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.621357798576355},{"id":"https://openalex.org/C123079801","wikidata":"https://www.wikidata.org/wiki/Q750240","display_name":"Modulation (music)","level":2,"score":0.5793092846870422},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5092195272445679},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.3609277904033661},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3349054455757141},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.295518159866333},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24314457178115845},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2217060923576355},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.21650275588035583},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09682270884513855},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:repository.arizona.edu:10150/565903","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10150/565903","pdf_url":null,"source":{"id":"https://openalex.org/S4306400271","display_name":"UA Campus Repository (The University of Arizona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138006243","host_organization_name":"University of Arizona","host_organization_lineage":["https://openalex.org/I138006243"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Dissertation"},{"id":"mag:1124157797","doi":null,"is_oa":false,"landing_page_url":"http://arizona.openrepository.com/arizona/handle/10150/565903","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":218,"referenced_works":["https://openalex.org/W20397492","https://openalex.org/W63581682","https://openalex.org/W68074898","https://openalex.org/W189597957","https://openalex.org/W270306878","https://openalex.org/W305284461","https://openalex.org/W1172163568","https://openalex.org/W1492744702","https://openalex.org/W1496512675","https://openalex.org/W1503265626","https://openalex.org/W1509709236","https://openalex.org/W1514240524","https://openalex.org/W1530526801","https://openalex.org/W1536858825","https://openalex.org/W1537531622","https://openalex.org/W1541441850","https://openalex.org/W1555852936","https://openalex.org/W1558650119","https://openalex.org/W1573923509","https://openalex.org/W1580112359","https://openalex.org/W1585415456","https://openalex.org/W1589137348","https://openalex.org/W1591384720","https://openalex.org/W1599318880","https://openalex.org/W1601532569","https://openalex.org/W1669823852","https://openalex.org/W1678355425","https://openalex.org/W1727542344","https://openalex.org/W1740455381","https://openalex.org/W1757146080","https://openalex.org/W1832218041","https://openalex.org/W1894078726","https://openalex.org/W1894311993","https://openalex.org/W1897692605","https://openalex.org/W1918496169","https://openalex.org/W1937743922","https://openalex.org/W1958166723","https://openalex.org/W1958948484","https://openalex.org/W1964854188","https://openalex.org/W1966044421","https://openalex.org/W1966324921","https://openalex.org/W1970348722","https://openalex.org/W1971933392","https://openalex.org/W1972100604","https://openalex.org/W1972425459","https://openalex.org/W1974873957","https://openalex.org/W1976109952","https://openalex.org/W1976169752","https://openalex.org/W1978178232","https://openalex.org/W1979190657","https://openalex.org/W1980767795","https://openalex.org/W1981804374","https://openalex.org/W1983113602","https://openalex.org/W1984082716","https://openalex.org/W1984329186","https://openalex.org/W1985164690","https://openalex.org/W1985170417","https://openalex.org/W1985768427","https://openalex.org/W1988849438","https://openalex.org/W1988883664","https://openalex.org/W1991994600","https://openalex.org/W1992618284","https://openalex.org/W1993736839","https://openalex.org/W1994434699","https://openalex.org/W1995321954","https://openalex.org/W1995891037","https://openalex.org/W1996151191","https://openalex.org/W1999612489","https://openalex.org/W2000026424","https://openalex.org/W2000060355","https://openalex.org/W2001183497","https://openalex.org/W2002055668","https://openalex.org/W2002761019","https://openalex.org/W2003029394","https://openalex.org/W2003564852","https://openalex.org/W2003898776","https://openalex.org/W2003922790","https://openalex.org/W2006409404","https://openalex.org/W2007169459","https://openalex.org/W2008180484","https://openalex.org/W2008624261","https://openalex.org/W2009866472","https://openalex.org/W2013586680","https://openalex.org/W2014396933","https://openalex.org/W2015013046","https://openalex.org/W2015667532","https://openalex.org/W2017558827","https://openalex.org/W2022545162","https://openalex.org/W2023003977","https://openalex.org/W2024404891","https://openalex.org/W2026755389","https://openalex.org/W2027465915","https://openalex.org/W2027541804","https://openalex.org/W2029545261","https://openalex.org/W2029613523","https://openalex.org/W2031043324","https://openalex.org/W2032633728","https://openalex.org/W2032846064","https://openalex.org/W2037084455","https://openalex.org/W2037414097","https://openalex.org/W2038334426","https://openalex.org/W2039180341","https://openalex.org/W2039358746","https://openalex.org/W2044659112","https://openalex.org/W2045045758","https://openalex.org/W2045465871","https://openalex.org/W2045541273","https://openalex.org/W2048635093","https://openalex.org/W2049486926","https://openalex.org/W2051028807","https://openalex.org/W2056356727","https://openalex.org/W2056527325","https://openalex.org/W2057540120","https://openalex.org/W2058483899","https://openalex.org/W2060586674","https://openalex.org/W2060920553","https://openalex.org/W2062613673","https://openalex.org/W2064094924","https://openalex.org/W2067143949","https://openalex.org/W2067438800","https://openalex.org/W2067674238","https://openalex.org/W2069038123","https://openalex.org/W2069182600","https://openalex.org/W2069746024","https://openalex.org/W2070887858","https://openalex.org/W2071003791","https://openalex.org/W2071292731","https://openalex.org/W2071355643","https://openalex.org/W2071569046","https://openalex.org/W2072060769","https://openalex.org/W2072759014","https://openalex.org/W2075157296","https://openalex.org/W2075212294","https://openalex.org/W2075877638","https://openalex.org/W2076229468","https://openalex.org/W2076272623","https://openalex.org/W2077516044","https://openalex.org/W2078000948","https://openalex.org/W2078125977","https://openalex.org/W2078509321","https://openalex.org/W2079249488","https://openalex.org/W2080917564","https://openalex.org/W2081251587","https://openalex.org/W2082861955","https://openalex.org/W2084462378","https://openalex.org/W2085514362","https://openalex.org/W2085538038","https://openalex.org/W2086068652","https://openalex.org/W2086262272","https://openalex.org/W2086542477","https://openalex.org/W2086898522","https://openalex.org/W2087361927","https://openalex.org/W2087635974","https://openalex.org/W2088274582","https://openalex.org/W2090196720","https://openalex.org/W2090542190","https://openalex.org/W2090651497","https://openalex.org/W2091165717","https://openalex.org/W2092978835","https://openalex.org/W2094034401","https://openalex.org/W2094530674","https://openalex.org/W2095107814","https://openalex.org/W2095136980","https://openalex.org/W2099370772","https://openalex.org/W2100020529","https://openalex.org/W2100975530","https://openalex.org/W2104228780","https://openalex.org/W2105623061","https://openalex.org/W2107226097","https://openalex.org/W2107773943","https://openalex.org/W2109613652","https://openalex.org/W2109821241","https://openalex.org/W2110185620","https://openalex.org/W2111274886","https://openalex.org/W2111846174","https://openalex.org/W2112893073","https://openalex.org/W2113215715","https://openalex.org/W2116286472","https://openalex.org/W2117851116","https://openalex.org/W2118582303","https://openalex.org/W2120428149","https://openalex.org/W2121289914","https://openalex.org/W2123256480","https://openalex.org/W2124878846","https://openalex.org/W2125086080","https://openalex.org/W2126160703","https://openalex.org/W2127023470","https://openalex.org/W2127238314","https://openalex.org/W2129876877","https://openalex.org/W2130109194","https://openalex.org/W2135946934","https://openalex.org/W2136207339","https://openalex.org/W2136829487","https://openalex.org/W2141789143","https://openalex.org/W2141943024","https://openalex.org/W2143323541","https://openalex.org/W2143726349","https://openalex.org/W2145404277","https://openalex.org/W2145718470","https://openalex.org/W2146089420","https://openalex.org/W2146116342","https://openalex.org/W2150899253","https://openalex.org/W2153050302","https://openalex.org/W2158177029","https://openalex.org/W2158808108","https://openalex.org/W2159206020","https://openalex.org/W2161274454","https://openalex.org/W2165472303","https://openalex.org/W2168467160","https://openalex.org/W2170749456","https://openalex.org/W2212384750","https://openalex.org/W2305283737","https://openalex.org/W2329534657","https://openalex.org/W2329785166","https://openalex.org/W2410000813","https://openalex.org/W2413680656","https://openalex.org/W2468421412","https://openalex.org/W2477287325"],"related_works":["https://openalex.org/W2279890600","https://openalex.org/W2000060355","https://openalex.org/W1995891037","https://openalex.org/W2914730902","https://openalex.org/W3006350604","https://openalex.org/W2190815521","https://openalex.org/W2805044115","https://openalex.org/W826921966","https://openalex.org/W1964753147","https://openalex.org/W3216797158"],"abstract_inverted_index":{"The":[0],"retina":[1,364,436],"is":[2,20,45,131,275,393],"able":[3],"to":[4,34,48,58,87,107,115,135,155,178,189,219,244,251,288,298,311,334,344,353,367,378,402,421],"adjust":[5],"its":[6],"signaling":[7,110],"over":[8],"a":[9,237,280,323,441],"wide":[10],"range":[11],"of":[12,18,39,63,70,125,192,286,315,407],"light":[13,50,141,148,169,308,355,397,431,448,453],"levels.":[14],"A":[15],"functional":[16],"result":[17],"this":[19,277],"increased":[21],"visual":[22,369,463],"acuity":[23],"at":[24,60,122],"brighter":[25],"luminance":[26],"levels,":[27],"such":[28],"as":[29,49,202],"during":[30],"the":[31,37,61,64,67,71,93,120,123,136,147,153,156,175,190,249,256,283,294,316,329,341,345,350,363,375,396],"day,":[32],"due":[33,104,343],"changes":[35,54,97,114,139,145,154,224,377,420],"in":[36,76,98,105,194,199,248,255,282,340,349,395,417,444],"organization":[38],"retinal":[40,109,126,200,208,408],"receptive":[41,81,320],"fields.":[42,321],"This":[43,357],"process":[44],"commonly":[46],"referred":[47],"adaptation.":[51],"These":[52],"organizational":[53],"have":[55,74,160],"been":[56,161,400],"shown":[57,401],"occur":[59],"level":[62],"ganglion":[65,99,230,336],"cells,":[66,119,186,273],"output":[68,227,333],"neurons":[69],"retina,":[72],"which":[73,187,455],"shifts":[75],"their":[77,85,226],"excitatory":[78],"center-inhibitory":[79],"surround":[80],"fields":[82],"that":[83,95,159,234,293,328,374,430],"increase":[84,368],"sensitivity":[86,102,464],"small":[88,354],"stimuli.":[89,356],"Recent":[90],"work":[91],"supports":[92],"idea":[94],"light-adapted":[96,217],"cell":[100,173,319,332],"spatial":[101,284,295,351],"are":[103,268,384,412],"part":[106],"inner":[108,435],"changes,":[111],"possibly":[112],"including":[113],"inhibition":[116,134,243,254,262,287,437],"onto":[117,228],"bipolar":[118,137,157,172,180,185,246,300,318,331,380,423],"interneurons":[121],"center":[124],"signal":[127,149],"processing.":[128],"However,":[129,410],"it":[130,274],"unknown":[132],"how":[133,143,168,221],"cells":[138,158,181,247,301,337,381],"with":[140,307,382],"adaptation,":[142,309],"any":[144,222],"affect":[146],"or":[150],"what":[151],"mediates":[152],"suggested":[162,327],"by":[163,270,387],"previous":[164],"reports.":[165],"To":[166],"determine":[167,220],"adaptation":[170,201,432],"affects":[171,225],"inhibition,":[174],"inhibitory":[176,223,296,313,376,419],"inputs":[177,211],"OFF":[179,184,245,299,317,330,379,422],"were":[182,212],"measured.":[183],"respond":[188],"offset":[191],"light,":[193,342],"particular":[195],"may":[196,456],"be":[197,360,403,458],"involved":[198,416],"they":[203],"bridge":[204],"dim-":[205],"and":[206,216,260,267,305,347,398,438,446,465],"bright-light":[207],"pathways.":[209],"Their":[210],"compared":[213],"between":[214],"dark-":[215],"conditions":[218,454],"downstream":[229,335],"cells.":[231,290,424],"We":[232,291],"found":[233,292,373],"there":[235,411],"was":[236,338],"compensatory":[238],"switch":[239,278],"from":[240],"primarily":[241,252],"glycinergic-mediated":[242],"dark":[250],"GABAergic-mediated":[253],"light.":[257],"Since":[258],"glycinergic":[259],"GABAergic":[261],"perform":[263],"very":[264],"different":[265,272,451],"roles":[266],"mediated":[269,386],"morphologically":[271],"likely":[276,413,439],"underlies":[279],"change":[281],"distribution":[285],"these":[289,426],"input":[297],"became":[302],"significantly":[303],"smaller":[304,312],"narrower":[306],"translating":[310],"surrounds":[314],"Through":[322,425],"model,":[324],"our":[325],"data":[326],"stronger":[339],"narrowing":[346],"reduction":[348],"input,":[352],"would":[358],"effectively":[359],"one":[361,459],"way":[362],"could":[365],"use":[366],"acuity.":[370,466],"Additionally,":[371],"we":[372,428],"light-adaptation":[383],"partially":[385],"dopamine":[388],"D1":[389],"receptor":[390],"signaling.":[391],"Dopamine":[392],"released":[394],"has":[399],"an":[404],"important":[405],"modulator":[406],"light-adaptation.":[409],"other":[414],"factors":[415],"mediating":[418],"studies,":[427],"show":[429],"heavily":[433],"influences":[434],"plays":[440],"prominent":[442],"role":[443],"determining":[445],"shaping":[447],"signals":[449],"under":[450],"ambient":[452],"ultimately":[457],"mechanism":[460],"for":[461],"increasing":[462]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
