{"id":"https://openalex.org/W1124084901","doi":"https://doi.org/10.1007/978-1-4471-6678-8_4","title":"Is Environmental Epigenetics Relevant to Endocrine Disease?","display_name":"Is Environmental Epigenetics Relevant to Endocrine Disease?","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1124084901","doi":"https://doi.org/10.1007/978-1-4471-6678-8_4","mag":"1124084901"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4471-6678-8_4","doi":"https://doi.org/10.1007/978-1-4471-6678-8_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4471-6678-8_4","pdf_url":null,"source":{"id":"https://openalex.org/S4210193569","display_name":"Molecular and integrative toxicology","issn_l":"2168-4219","issn":["2168-4219","2168-4235"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Integrative Toxicology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4243292916","display_name":"Environmental Epigenetics"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020567229","display_name":"Abby F. Fleisch","orcid":"https://orcid.org/0000-0002-2789-6412","observed_orcids":["https://orcid.org/0000-0002-2789-6412"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Abby F. Fleisch","raw_affiliation_strings":["Division of Endocrinology, Boston Children\u2019s Hospital, Boston, MA, USA","Division of Endocrinology, Boston Children's Hospital, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Boston Children\u2019s Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]},{"raw_affiliation_string":"Division of Endocrinology, Boston Children's Hospital, Boston, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012824375","display_name":"Robert O. Wright","orcid":"https://orcid.org/0000-0003-1180-6459","observed_orcids":["https://orcid.org/0000-0003-1180-6459","https://orcid.org/0000-0002-4262-2807","https://orcid.org/0000-0001-6079-2749"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert O. Wright","raw_affiliation_strings":["Department of Preventive Medicine and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA","Department of Preventive Medicine and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Preventive Medicine and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069636788","display_name":"Andrea Baccarelli","orcid":"https://orcid.org/0000-0002-3436-0640","observed_orcids":["https://orcid.org/0000-0002-3436-0640"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea A. Baccarelli","raw_affiliation_strings":["Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA","Department of Environmental Health, Harvard School of Public Health, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Environmental Health, Harvard School of Public Health, Boston, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5020567229"],"corresponding_institution_ids":["https://openalex.org/I1288882113"],"apc_list":null,"apc_paid":null,"fwci":0.5327,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.63276968,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"55","last_page":"74"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.0203000009059906,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/environmental-epigenetics","display_name":"environmental epigenetics","score":0.9990000128746033},{"id":"https://openalex.org/keywords/endocrine-disruptors","display_name":"endocrine disruptors","score":0.9750000238418579},{"id":"https://openalex.org/keywords/epigenetic-regulation","display_name":"epigenetic regulation","score":0.7080000042915344},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/histone-modifications","display_name":"histone modifications","score":0.9890000224113464},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.9440000057220459},{"id":"https://openalex.org/keywords/transgenerational-epigenetic-inheritance","display_name":"transgenerational epigenetic inheritance","score":0.9649999737739563},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.8980000019073486},{"id":"https://openalex.org/keywords/ionizing-radiation","display_name":"ionizing radiation","score":0.9049999713897705},{"id":"https://openalex.org/keywords/hormone-receptor-signaling","display_name":"hormone receptor signaling","score":0.3930000066757202}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6801883578300476},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.6247172951698303},{"id":"https://openalex.org/C2776869705","wikidata":"https://www.wikidata.org/wiki/Q2661443","display_name":"Endocrine disease","level":4,"score":0.515038013458252},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3695530295372009},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34829825162887573},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33346593379974365},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3258854150772095},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24924200773239136},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15027427673339844},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.07682916522026062},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4471-6678-8_4","doi":"https://doi.org/10.1007/978-1-4471-6678-8_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4471-6678-8_4","pdf_url":null,"source":{"id":"https://openalex.org/S4210193569","display_name":"Molecular and integrative toxicology","issn_l":"2168-4219","issn":["2168-4219","2168-4235"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-20"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Integrative Toxicology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9074000120162964}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":95,"referenced_works":["https://openalex.org/W18258351","https://openalex.org/W172536849","https://openalex.org/W1486257535","https://openalex.org/W1487412251","https://openalex.org/W1572982878","https://openalex.org/W1608964217","https://openalex.org/W1693408209","https://openalex.org/W1784857457","https://openalex.org/W1821797507","https://openalex.org/W1914833882","https://openalex.org/W1932533342","https://openalex.org/W1963781146","https://openalex.org/W1965739931","https://openalex.org/W1971708895","https://openalex.org/W1981965784","https://openalex.org/W1989457196","https://openalex.org/W1993185333","https://openalex.org/W1993756347","https://openalex.org/W1995627657","https://openalex.org/W1997453048","https://openalex.org/W1998657660","https://openalex.org/W1998970086","https://openalex.org/W2001070286","https://openalex.org/W2004622373","https://openalex.org/W2009396016","https://openalex.org/W2011474247","https://openalex.org/W2014333106","https://openalex.org/W2017060001","https://openalex.org/W2019306356","https://openalex.org/W2024498651","https://openalex.org/W2030864780","https://openalex.org/W2036263818","https://openalex.org/W2036598382","https://openalex.org/W2038622868","https://openalex.org/W2038722690","https://openalex.org/W2041124206","https://openalex.org/W2045894781","https://openalex.org/W2046744395","https://openalex.org/W2052686784","https://openalex.org/W2053621737","https://openalex.org/W2053659717","https://openalex.org/W2053985016","https://openalex.org/W2054513817","https://openalex.org/W2057819889","https://openalex.org/W2062211740","https://openalex.org/W2062952077","https://openalex.org/W2065751798","https://openalex.org/W2067323501","https://openalex.org/W2069215536","https://openalex.org/W2071162594","https://openalex.org/W2077861918","https://openalex.org/W2081422943","https://openalex.org/W2083937864","https://openalex.org/W2085600699","https://openalex.org/W2087008478","https://openalex.org/W2090055934","https://openalex.org/W2091414779","https://openalex.org/W2091613175","https://openalex.org/W2091658754","https://openalex.org/W2096177579","https://openalex.org/W2099876016","https://openalex.org/W2100477217","https://openalex.org/W2101037833","https://openalex.org/W2101526557","https://openalex.org/W2102083376","https://openalex.org/W2106694682","https://openalex.org/W2107594198","https://openalex.org/W2108628225","https://openalex.org/W2109881276","https://openalex.org/W2117391818","https://openalex.org/W2118871005","https://openalex.org/W2123892768","https://openalex.org/W2127056941","https://openalex.org/W2127349594","https://openalex.org/W2130189740","https://openalex.org/W2130597092","https://openalex.org/W2131130277","https://openalex.org/W2131229011","https://openalex.org/W2135471644","https://openalex.org/W2135518377","https://openalex.org/W2136326352","https://openalex.org/W2141642891","https://openalex.org/W2143858605","https://openalex.org/W2145918648","https://openalex.org/W2149830483","https://openalex.org/W2150095915","https://openalex.org/W2150603155","https://openalex.org/W2150856909","https://openalex.org/W2155676752","https://openalex.org/W2155681361","https://openalex.org/W2156735784","https://openalex.org/W2162674813","https://openalex.org/W2165700542","https://openalex.org/W2170493345","https://openalex.org/W4290960820"],"related_works":["https://openalex.org/W2153796004","https://openalex.org/W7127166886","https://openalex.org/W3043841640","https://openalex.org/W7167267901","https://openalex.org/W2078899903","https://openalex.org/W3112144434","https://openalex.org/W1483855721","https://openalex.org/W4380318127","https://openalex.org/W2749638421","https://openalex.org/W2178495277"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}