{"id":"https://openalex.org/W1121595694","doi":null,"title":"Gastric motility: Measurement, symptoms and therapy","display_name":"Gastric motility: Measurement, symptoms and therapy","publication_year":2008,"publication_date":"2008-09-26","ids":{"openalex":"https://openalex.org/W1121595694","mag":"1121595694"},"language":"en","primary_location":{"id":"pmh:oai:helda.helsinki.fi:10138/22986","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10138/22986","pdf_url":null,"source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["ddh","jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10138/22986","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023934960","display_name":"Jari Punkkinen","orcid":"https://orcid.org/0000-0002-3993-819X","observed_orcids":["https://orcid.org/0000-0002-3993-819X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jari Punkkinen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5023934960"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastric-motility-disorders","display_name":"gastric motility disorders","score":0.8870000243186951},{"id":"https://openalex.org/keywords/delayed-gastric-emptying","display_name":"delayed gastric emptying","score":0.9110000133514404},{"id":"https://openalex.org/keywords/diabetic-gastroparesis","display_name":"diabetic gastroparesis","score":0.9079999923706055},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.906000018119812},{"id":"https://openalex.org/keywords/functional-dyspepsia","display_name":"functional dyspepsia","score":0.9580000042915344},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9950000047683716},{"id":"https://openalex.org/keywords/13c-octanoic-acid-breath-test","display_name":"13C-octanoic acid breath test","score":0.8640000224113464},{"id":"https://openalex.org/keywords/radionuclide-imaging","display_name":"scintigraphy","score":0.7820000052452087},{"id":"https://openalex.org/keywords/electrogastrography","display_name":"electrogastrography","score":0.9459999799728394},{"id":"https://openalex.org/keywords/gastric-slow-waves","display_name":"gastric slow waves","score":0.8519999980926514},{"id":"https://openalex.org/keywords/nizatidine","display_name":"nizatidine","score":0.7710000276565552},{"id":"https://openalex.org/keywords/prokinetic-drugs","display_name":"prokinetic drugs","score":0.746999979019165},{"id":"https://openalex.org/keywords/autonomic-neuropathy","display_name":"autonomic neuropathy","score":0.8799999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45788776874542236}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:helda.helsinki.fi:10138/22986","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10138/22986","pdf_url":null,"source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["ddh","jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoralThesis"},{"id":"mag:1121595694","doi":null,"is_oa":false,"landing_page_url":"https://helda.helsinki.fi/bitstream/10138/22986/1/gastricm.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:helda.helsinki.fi:10138/22986","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10138/22986","pdf_url":null,"source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["ddh","jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":173,"referenced_works":["https://openalex.org/W31078748","https://openalex.org/W33315382","https://openalex.org/W69020603","https://openalex.org/W70249653","https://openalex.org/W86210223","https://openalex.org/W90849382","https://openalex.org/W115618438","https://openalex.org/W132375180","https://openalex.org/W133856627","https://openalex.org/W155424429","https://openalex.org/W179146026","https://openalex.org/W184093693","https://openalex.org/W192970844","https://openalex.org/W202162180","https://openalex.org/W242894085","https://openalex.org/W265734301","https://openalex.org/W1513949244","https://openalex.org/W1534561431","https://openalex.org/W1535517181","https://openalex.org/W1603327495","https://openalex.org/W1607423153","https://openalex.org/W1658076298","https://openalex.org/W1805824803","https://openalex.org/W1813104943","https://openalex.org/W1841462180","https://openalex.org/W1947528570","https://openalex.org/W1963969020","https://openalex.org/W1964014336","https://openalex.org/W1964376194","https://openalex.org/W1966133025","https://openalex.org/W1966566333","https://openalex.org/W1968128120","https://openalex.org/W1969342338","https://openalex.org/W1970183414","https://openalex.org/W1971856590","https://openalex.org/W1973005829","https://openalex.org/W1976149361","https://openalex.org/W1976676485","https://openalex.org/W1977807712","https://openalex.org/W1979367855","https://openalex.org/W1984471157","https://openalex.org/W1985088203","https://openalex.org/W1986121938","https://openalex.org/W1988909786","https://openalex.org/W1989697076","https://openalex.org/W1989845723","https://openalex.org/W1990006831","https://openalex.org/W1990698232","https://openalex.org/W1991070573","https://openalex.org/W1993329622","https://openalex.org/W1995438902","https://openalex.org/W1995999141","https://openalex.org/W1999274639","https://openalex.org/W1999346440","https://openalex.org/W2001136165","https://openalex.org/W2001357215","https://openalex.org/W2001597080","https://openalex.org/W2004313956","https://openalex.org/W2004680277","https://openalex.org/W2005865101","https://openalex.org/W2006128463","https://openalex.org/W2007701360","https://openalex.org/W2009412074","https://openalex.org/W2011802448","https://openalex.org/W2013371242","https://openalex.org/W2013408103","https://openalex.org/W2016352914","https://openalex.org/W2017872822","https://openalex.org/W2018677788","https://openalex.org/W2019447315","https://openalex.org/W2020151607","https://openalex.org/W2021240874","https://openalex.org/W2021421843","https://openalex.org/W2021818870","https://openalex.org/W2024164039","https://openalex.org/W2025213762","https://openalex.org/W2026842737","https://openalex.org/W2028198940","https://openalex.org/W2029073901","https://openalex.org/W2029274902","https://openalex.org/W2029911061","https://openalex.org/W2031276263","https://openalex.org/W2033541852","https://openalex.org/W2034368445","https://openalex.org/W2037201003","https://openalex.org/W2039890850","https://openalex.org/W2044947078","https://openalex.org/W2045064077","https://openalex.org/W2046660901","https://openalex.org/W2049440415","https://openalex.org/W2049765836","https://openalex.org/W2049846847","https://openalex.org/W2050278073","https://openalex.org/W2054271473","https://openalex.org/W2054782808","https://openalex.org/W2054949836","https://openalex.org/W2055929172","https://openalex.org/W2061482115","https://openalex.org/W2061519578","https://openalex.org/W2061902184","https://openalex.org/W2062013642","https://openalex.org/W2062050992","https://openalex.org/W2064945708","https://openalex.org/W2065345014","https://openalex.org/W2067234575","https://openalex.org/W2069019124","https://openalex.org/W2072371345","https://openalex.org/W2072385395","https://openalex.org/W2073616832","https://openalex.org/W2078658164","https://openalex.org/W2080346447","https://openalex.org/W2080986537","https://openalex.org/W2081678747","https://openalex.org/W2082420583","https://openalex.org/W2082596952","https://openalex.org/W2083594541","https://openalex.org/W2083995065","https://openalex.org/W2085521848","https://openalex.org/W2089375608","https://openalex.org/W2090004842","https://openalex.org/W2091459554","https://openalex.org/W2093665896","https://openalex.org/W2094295387","https://openalex.org/W2096436906","https://openalex.org/W2099992271","https://openalex.org/W2106314041","https://openalex.org/W2109879785","https://openalex.org/W2111341963","https://openalex.org/W2114053326","https://openalex.org/W2117935569","https://openalex.org/W2118516610","https://openalex.org/W2122452022","https://openalex.org/W2124023802","https://openalex.org/W2127611187","https://openalex.org/W2129114009","https://openalex.org/W2129980920","https://openalex.org/W2131073992","https://openalex.org/W2132407181","https://openalex.org/W2135834619","https://openalex.org/W2136348956","https://openalex.org/W2141466583","https://openalex.org/W2145407244","https://openalex.org/W2146079901","https://openalex.org/W2150416321","https://openalex.org/W2152703178","https://openalex.org/W2153335875","https://openalex.org/W2154508925","https://openalex.org/W2155274481","https://openalex.org/W2157103773","https://openalex.org/W2157416528","https://openalex.org/W2164139561","https://openalex.org/W2167411320","https://openalex.org/W2168760107","https://openalex.org/W2185802037","https://openalex.org/W2187804661","https://openalex.org/W2243607894","https://openalex.org/W2264800746","https://openalex.org/W2285772130","https://openalex.org/W2313645769","https://openalex.org/W2319721330","https://openalex.org/W2327120124","https://openalex.org/W2327122843","https://openalex.org/W2330817593","https://openalex.org/W2334848097","https://openalex.org/W2346658448","https://openalex.org/W2361153334","https://openalex.org/W2407973560","https://openalex.org/W2418367649","https://openalex.org/W2420474657","https://openalex.org/W2427712193","https://openalex.org/W2922598414","https://openalex.org/W4250685527","https://openalex.org/W4251137455"],"related_works":["https://openalex.org/W2185147088","https://openalex.org/W2417372894","https://openalex.org/W2371070138","https://openalex.org/W2397718894","https://openalex.org/W2044461733","https://openalex.org/W2331050613","https://openalex.org/W1990251290","https://openalex.org/W2166452996","https://openalex.org/W2151250256","https://openalex.org/W3145249567"],"abstract_inverted_index":{"Gastric":[0,255],"motility":[1,135,155],"disorders,":[2,15],"including":[3],"delayed":[4,193],"gastric":[5,13,59,98,134,154,166,194,227,246,297,314,328,364,373],"emptying":[6,99,195,228,247,256,298,365,374],"(gastroparesis),":[7],"impaired":[8,216],"postprandial":[9],"fundic":[10,217],"relaxation,":[11],"and":[12,25,38,68,118,144,260,282,323,336,345,377],"myoelectrical":[14],"can":[16],"occur":[17],"in":[18,57,111,136,169,210,264,273,286,299,309,320,341,362],"type":[19,139,188,342],"1":[20,140,189,343],"diabetes,":[21,141],"chronic":[22,145],"renal":[23,146],"failure,":[24],"functional":[26,142],"dyspepsia":[27],"(FD).":[28],"Symptoms":[29],"like":[30],"upper":[31],"abdominal":[32,241],"pain,":[33],"early":[34],"satiation,":[35],"bloating,":[36],"nausea":[37],"vomiting":[39],"may":[40],"be":[41],"related":[42,48],"to":[43,49,71,176,182,245,349],"gastroparesis.":[44],"Diabetic":[45],"gastroparesis":[46],"is":[47,53,63,91,355],"autonomic":[50,220],"neuropathy.":[51],"Scintigraphy":[52],"the":[54,78,82,107,112,116,120,124,161,187,206,213,226,252,276,310,313,321,378,382],"gold":[55],"standard":[56],"measuring":[58,97,133,363],"emptying,":[60,167],"but":[61,235,268,289],"it":[62,369],"expensive,":[64],"requires":[65],"specific":[66],"equipment,":[67],"exposes":[69],"patients":[70,137,267,301,322],"radiation.":[72],"It":[73],"also":[74],"gives":[75],"information":[76,371],"about":[77,372],"intragastric":[79,203,249,270,379],"distribution":[80,204,250,271,380],"of":[81,96,115,123,132,163,196,205,212,230,251,257,275,284,293,312,331,366,375,381],"test":[83,89,207,253,384],"meal.":[84,254,385],"The":[85,219,325],"13C-octanoic":[86],"acid":[87],"breath":[88],"(OBT)":[90],"an":[92],"alternative,":[93],"indirect":[94],"method":[95],"with":[100,138,225],"a":[101,178],"stable":[102],"isotope.":[103],"Electrogastrography":[104],"(EGG)":[105],"registers":[106],"slow":[108,315],"wave":[109],"originating":[110],"pacemaker":[113],"area":[114],"stomach":[117],"regulating":[119],"peristaltic":[121],"contractions":[122],"antrum.":[125],"This":[126],"study":[127],"compares":[128],"these":[129],"three":[130],"methods":[131],"dyspepsia,":[143],"failure.":[147],"Currently":[148],"no":[149],"effective":[150],"drugs":[151],"for":[152],"treating":[153],"disorders":[156],"are":[157],"available.":[158],"We":[159],"studied":[160],"effect":[162,180],"nizatidine":[164,295],"on":[165],"because":[168],"preliminary":[170],"studies":[171],"this":[172,350],"drug":[173],"has":[174],"proven":[175],"have":[177],"prokinetic":[179],"due":[181],"its":[183],"cholinergic":[184],"properties.":[185],"Of":[186],"patients,":[190,214,288],"26%":[191],"had":[192],"solids":[197,231,259,332],"as":[198],"measured":[199,317,333],"by":[200,318,334],"scintigraphy.":[201],"Abnormal":[202],"meal":[208],"occurred":[209,272],"37%":[211],"indicating":[215],"relaxation.":[218],"neuropathy":[221],"score":[222],"correlated":[223],"positively":[224],"rate":[229],"(P":[232,302],"=":[233],"0.006),":[234],"HbA1C,":[236],"plasma":[237],"glucose":[238],"levels,":[239],"or":[240,248,360],"symptoms":[242],"were":[243],"unrelated":[244],"both":[258,340],"liquids":[261,376],"was":[262,338],"normal":[263],"all":[265],"FD":[266,287,300,346],"abnormal":[269],"38%":[274],"patients.":[277,347],"Nizatidine":[278],"improved":[279],"symptom":[280],"scores":[281],"quality":[283],"life":[285],"not":[290],"significantly.":[291],"Instead":[292],"enhancing,":[294],"slowed":[296],"<":[303],"0.05).":[304],"No":[305],"significant":[306],"difference":[307],"appeared":[308],"frequency":[311],"waves":[316],"EGG":[319,361],"controls.":[324],"correlation":[326],"between":[327],"half-emptying":[329],"times":[330],"scintigraphy":[335,354],"OBT":[337,359],"poor":[339],"diabetes":[344],"According":[348],"study,":[351],"dynamic":[352],"dual-tracer":[353],"more":[356],"accurate":[357],"than":[358],"solids.":[367],"Additionally":[368],"provides":[370],"ingested":[383]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
