{"id":"https://openalex.org/W112086181","doi":"https://doi.org/10.1007/978-1-4613-3476-7_2","title":"Regulation and Functions of Escherichia coli Genes Induced by DNA Damage","display_name":"Regulation and Functions of Escherichia coli Genes Induced by DNA Damage","publication_year":1982,"publication_date":"1982-01-01","ids":{"openalex":"https://openalex.org/W112086181","doi":"https://doi.org/10.1007/978-1-4613-3476-7_2","mag":"112086181","pmid":"https://pubmed.ncbi.nlm.nih.gov/6287997"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4613-3476-7_2","doi":"https://doi.org/10.1007/978-1-4613-3476-7_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4613-3476-7_2","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Mechanisms of Mutagenesis","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W619816389","display_name":"Molecular and Cellular Mechanisms of Mutagenesis"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112719442","display_name":"Graham Charles Walker","orcid":"https://orcid.org/0000-0001-7243-8261","observed_orcids":["https://orcid.org/0000-0001-7243-8261"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Graham C. Walker","raw_affiliation_strings":["Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053475144","display_name":"Cynthia J. Kenyon","orcid":"https://orcid.org/0000-0003-3446-2636","observed_orcids":["https://orcid.org/0000-0003-3446-2636"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cynthia J. Kenyon","raw_affiliation_strings":["Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000425451","display_name":"Anne Britt","orcid":"https://orcid.org/0000-0003-2244-1790","observed_orcids":["https://orcid.org/0000-0003-2244-1790"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anne Bagg","raw_affiliation_strings":["Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025914907","display_name":"Stephen Joseph Elledge","orcid":"https://orcid.org/0000-0001-7923-6283","observed_orcids":["https://orcid.org/0000-0001-7923-6283"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen J. Elledge","raw_affiliation_strings":["Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105369341","display_name":"Karen L. Perry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen L. Perry","raw_affiliation_strings":["Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016667558","display_name":"William G. Shanabruch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William G. Shanabruch","raw_affiliation_strings":["Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":null,"apc_paid":null,"fwci":4.9677,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.95499408,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":null,"first_page":"43","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.8633000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.8633000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.13449999690055847,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8939999938011169},{"id":"https://openalex.org/keywords/dna-damage-response","display_name":"DNA damage response","score":0.8880000114440918},{"id":"https://openalex.org/keywords/dna-repair-genes","display_name":"DNA repair genes","score":0.6039999723434448},{"id":"https://openalex.org/keywords/uvra","display_name":"uvrA","score":0.8209999799728394},{"id":"https://openalex.org/keywords/uvrb","display_name":"UvrB","score":1.0},{"id":"https://openalex.org/keywords/umuc","display_name":"UmuC","score":0.8610000014305115},{"id":"https://openalex.org/keywords/lexa-repressor","display_name":"LexA repressor","score":0.7419999837875366},{"id":"https://openalex.org/keywords/uv-mutagenesis","display_name":"UV mutagenesis","score":0.5960000157356262},{"id":"https://openalex.org/keywords/chemical-mutagenesis","display_name":"chemical mutagenesis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/pyrimidine-dimer-excision","display_name":"pyrimidine dimer excision","score":0.7360000014305115},{"id":"https://openalex.org/keywords/weigle-reactivation","display_name":"Weigle reactivation","score":0.6859999895095825},{"id":"https://openalex.org/keywords/bacteriophage-lambda","display_name":"bacteriophage lambda","score":0.8389999866485596}],"concepts":[{"id":"https://openalex.org/C413212","wikidata":"https://www.wikidata.org/wiki/Q7314274","display_name":"Repressor lexA","level":5,"score":0.9730418920516968},{"id":"https://openalex.org/C2780852648","wikidata":"https://www.wikidata.org/wiki/Q143584","display_name":"SOS response","level":4,"score":0.7389436364173889},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.6949617266654968},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6329295635223389},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.608467698097229},{"id":"https://openalex.org/C203075996","wikidata":"https://www.wikidata.org/wiki/Q139677","display_name":"Operon","level":4,"score":0.578536331653595},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5603402853012085},{"id":"https://openalex.org/C158448853","wikidata":"https://www.wikidata.org/wiki/Q425218","display_name":"Repressor","level":4,"score":0.5113041400909424},{"id":"https://openalex.org/C16318435","wikidata":"https://www.wikidata.org/wiki/Q149299","display_name":"Mutagenesis","level":4,"score":0.4998321533203125},{"id":"https://openalex.org/C170344550","wikidata":"https://www.wikidata.org/wiki/Q311359","display_name":"lac operon","level":4,"score":0.4766714870929718},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.4646705090999603},{"id":"https://openalex.org/C111829193","wikidata":"https://www.wikidata.org/wiki/Q1108970","display_name":"Fusion gene","level":3,"score":0.43696129322052},{"id":"https://openalex.org/C167975912","wikidata":"https://www.wikidata.org/wiki/Q1018722","display_name":"Pyrimidine dimer","level":4,"score":0.43424949049949646},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.41991183161735535},{"id":"https://openalex.org/C195286587","wikidata":"https://www.wikidata.org/wiki/Q424689","display_name":"Gene product","level":4,"score":0.41488033533096313},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32614022493362427},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.27684077620506287},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2590044140815735}],"mesh":[{"descriptor_ui":"D000099160","descriptor_name":"LexA Repressor Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005798","descriptor_name":"Genes, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009876","descriptor_name":"Operon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011938","descriptor_name":"Rec A Recombinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012697","descriptor_name":"Serine Endopeptidases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4613-3476-7_2","doi":"https://doi.org/10.1007/978-1-4613-3476-7_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4613-3476-7_2","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Mechanisms of Mutagenesis","raw_type":"book-chapter"},{"id":"pmid:6287997","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6287997","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Basic life sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8022458919","display_name":"Mutagenesis and Repair of DNA","funder_award_id":"R01CA021615","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W173195082","https://openalex.org/W252282098","https://openalex.org/W654084456","https://openalex.org/W1484984821","https://openalex.org/W1497428774","https://openalex.org/W1524519228","https://openalex.org/W1571486880","https://openalex.org/W1876873753","https://openalex.org/W1923728284","https://openalex.org/W1949490448","https://openalex.org/W1964222690","https://openalex.org/W1968724116","https://openalex.org/W1969107625","https://openalex.org/W1972168834","https://openalex.org/W1975833216","https://openalex.org/W1976917904","https://openalex.org/W1979410044","https://openalex.org/W1994331558","https://openalex.org/W2001949463","https://openalex.org/W2008138719","https://openalex.org/W2009774203","https://openalex.org/W2011609668","https://openalex.org/W2013260256","https://openalex.org/W2016059862","https://openalex.org/W2024208506","https://openalex.org/W2024607163","https://openalex.org/W2027024460","https://openalex.org/W2028048169","https://openalex.org/W2029720465","https://openalex.org/W2057180282","https://openalex.org/W2059390535","https://openalex.org/W2068270570","https://openalex.org/W2077069371","https://openalex.org/W2081800325","https://openalex.org/W2085730824","https://openalex.org/W2087831370","https://openalex.org/W2088471086","https://openalex.org/W2089679446","https://openalex.org/W2092650123","https://openalex.org/W2093679000","https://openalex.org/W2105255726","https://openalex.org/W2154936481","https://openalex.org/W2154960399","https://openalex.org/W2218142413","https://openalex.org/W2279397270","https://openalex.org/W2318287821","https://openalex.org/W2411855170","https://openalex.org/W2485968509","https://openalex.org/W2761639897","https://openalex.org/W3183899877","https://openalex.org/W4323019079","https://openalex.org/W6637445736"],"related_works":["https://openalex.org/W2401777461","https://openalex.org/W2093679000","https://openalex.org/W2001949463","https://openalex.org/W1989759588","https://openalex.org/W2027024460","https://openalex.org/W1033252775","https://openalex.org/W1618490316","https://openalex.org/W147431913","https://openalex.org/W2000120323","https://openalex.org/W1974210160"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
