{"id":"https://openalex.org/W111993323","doi":null,"title":"Cushing's syndrome and autoimmunity.","display_name":"Cushing's syndrome and autoimmunity.","publication_year":1979,"publication_date":"1979-05-01","ids":{"openalex":"https://openalex.org/W111993323","mag":"111993323","pmid":"https://pubmed.ncbi.nlm.nih.gov/110282"},"language":"en","primary_location":{"id":"pmid:110282","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/110282","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of pathology & laboratory medicine","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110105804","display_name":"J A Andrada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J A Andrada","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087149160","display_name":"Frederick T. Murray","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F T Murray","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036241800","display_name":"Enia Comini Andrada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E C Andrada","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5029207203","display_name":"CALVIN EZRIN","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Ezrin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6778,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.66262918,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"103","issue":"5","first_page":"244","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.22360000014305115,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cushing-s-syndrome","display_name":"Cushing's syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.8080000281333923},{"id":"https://openalex.org/keywords/adrenal-autoantibodies","display_name":"adrenal autoantibodies","score":0.8309999704360962},{"id":"https://openalex.org/keywords/adrenal-nodular-hyperplasia","display_name":"adrenal nodular hyperplasia","score":0.8629999756813049},{"id":"https://openalex.org/keywords/pituitary-cushing-s-disease","display_name":"pituitary Cushing's disease","score":0.8769999742507935}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.79990553855896},{"id":"https://openalex.org/C152669594","wikidata":"https://www.wikidata.org/wiki/Q904197","display_name":"Complement fixation test","level":4,"score":0.7157238721847534},{"id":"https://openalex.org/C2908812692","wikidata":"https://www.wikidata.org/wiki/Q3269477","display_name":"Lymphocytic infiltration","level":2,"score":0.7024052739143372},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.6608744263648987},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.6244314908981323},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.539810836315155},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.5372889041900635},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4942953586578369},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.4832497239112854},{"id":"https://openalex.org/C153400128","wikidata":"https://www.wikidata.org/wiki/Q3150731","display_name":"Infiltration (HVAC)","level":2,"score":0.48243221640586853},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.47885891795158386},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.11025205254554749},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000311","descriptor_name":"Adrenal Glands","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003168","descriptor_name":"Complement Fixation Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003480","descriptor_name":"Cushing Syndrome","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005779","descriptor_name":"Immunodiffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006386","descriptor_name":"Hemagglutination Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:110282","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/110282","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of pathology & laboratory medicine","raw_type":"Case Reports"},{"id":"mag:111993323","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/110282","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2024917635","https://openalex.org/W2409863820","https://openalex.org/W1964557937","https://openalex.org/W1985274810","https://openalex.org/W2394856477","https://openalex.org/W2474491679","https://openalex.org/W2410215679","https://openalex.org/W2409435944","https://openalex.org/W2129043014","https://openalex.org/W2320541385"],"abstract_inverted_index":{"Is":[0],"Cushing's":[1,23],"syndrome":[2],"ever":[3],"caused":[4],"by":[5],"adrenal":[6,44,61,81],"stimulating":[7],"autoantibodies?":[8],"Specific":[9],"antiadrenal":[10],"antibodies":[11,82],"were":[12,32],"found":[13],"in":[14,47,50,70],"the":[15,43,76],"serum":[16],"of":[17,19,42,52,59],"three":[18],"seven":[20],"patients":[21],"with":[22,63,72],"syndrome.":[24],"The":[25],"immunologic":[26],"techniques":[27],"that":[28],"showed":[29],"positive":[30],"results":[31],"complement":[33],"fixation,":[34],"tanned":[35],"RBC":[36],"hemagglutination,":[37],"and":[38,79],"immunofluorescence.":[39],"Lymphocytic":[40],"infiltration":[41],"was":[45],"present":[46],"two":[48],"cases,":[49],"one":[51],"which":[53],"nodular":[54],"hyperplasia":[55],"seemed":[56],"to":[57,86],"be":[58],"primary":[60],"origin":[62],"autoimmunity":[64],"as":[65],"a":[66],"possible":[67],"cause.":[68],"However,":[69],"cases":[71],"clear-cut":[73],"pituitary":[74],"origin,":[75],"lymphocytic":[77],"adrenalitis":[78],"circulating":[80],"are":[83],"likely":[84],"secondary":[85],"antigen":[87],"leaking":[88],"from":[89],"damaged":[90],"tissue.":[91]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}