{"id":"https://openalex.org/W111437162","doi":null,"title":"Resveratrol + ethanol preconditioning and neuroprotection","display_name":"Resveratrol + ethanol preconditioning and neuroprotection","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W111437162","mag":"111437162"},"language":"en","primary_location":{"id":"pmh:oai:ecommons.luc.edu:luc_theses-1822","doi":null,"is_oa":true,"landing_page_url":"https://ecommons.luc.edu/luc_theses/823","pdf_url":"https://ecommons.luc.edu/luc_theses/823","source":{"id":"https://openalex.org/S4306402030","display_name":"Loyola eCommons (Loyola University of Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1925986","host_organization_name":"Loyola University Chicago","host_organization_lineage":["https://openalex.org/I1925986"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Master's Theses","raw_type":"text"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ecommons.luc.edu/luc_theses/823","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057036793","display_name":"Nastaran Khodaie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nastaran Khodaie","raw_affiliation_strings":["#N#        Loyola University, Chicago"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"#N#        Loyola University, Chicago","institution_ids":["https://openalex.org/I1925986"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5057036793"],"corresponding_institution_ids":["https://openalex.org/I1925986"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9106000065803528,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9106000065803528,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11051","display_name":"Sirtuins and Resveratrol in Medicine","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.009399999864399433,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/resveratrol","display_name":"resveratrol","score":0.9950000047683716},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.8220000267028809},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.5329999923706055},{"id":"https://openalex.org/keywords/synergistic-protection","display_name":"synergistic protection","score":0.7889999747276306},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C2776816829","wikidata":"https://www.wikidata.org/wiki/Q407329","display_name":"Resveratrol","level":2,"score":0.9475510716438293},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.8148903846740723},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.7766442894935608},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.755233645439148},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6395296454429626},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5661351680755615},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.43667858839035034},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3955652713775635},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16470098495483398},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.04106324911117554},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ecommons.luc.edu:luc_theses-1822","doi":null,"is_oa":true,"landing_page_url":"https://ecommons.luc.edu/luc_theses/823","pdf_url":"https://ecommons.luc.edu/luc_theses/823","source":{"id":"https://openalex.org/S4306402030","display_name":"Loyola eCommons (Loyola University of Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1925986","host_organization_name":"Loyola University Chicago","host_organization_lineage":["https://openalex.org/I1925986"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Master's Theses","raw_type":"text"},{"id":"mag:111437162","doi":null,"is_oa":false,"landing_page_url":"https://ecommons.luc.edu/cgi/viewcontent.cgi?article=1822&context=luc_theses","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:ecommons.luc.edu:luc_theses-1822","doi":null,"is_oa":true,"landing_page_url":"https://ecommons.luc.edu/luc_theses/823","pdf_url":"https://ecommons.luc.edu/luc_theses/823","source":{"id":"https://openalex.org/S4306402030","display_name":"Loyola eCommons (Loyola University of Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1925986","host_organization_name":"Loyola University Chicago","host_organization_lineage":["https://openalex.org/I1925986"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Master's Theses","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W111437162.pdf","grobid_xml":"https://content.openalex.org/works/W111437162.grobid-xml"},"referenced_works_count":83,"referenced_works":["https://openalex.org/W1486012879","https://openalex.org/W1789813876","https://openalex.org/W1805975457","https://openalex.org/W1902469108","https://openalex.org/W1926151057","https://openalex.org/W1966350354","https://openalex.org/W1969728057","https://openalex.org/W1969962826","https://openalex.org/W1979148107","https://openalex.org/W1982317469","https://openalex.org/W1985148856","https://openalex.org/W1996721832","https://openalex.org/W1998779872","https://openalex.org/W1999481655","https://openalex.org/W2018354461","https://openalex.org/W2018994056","https://openalex.org/W2019204835","https://openalex.org/W2019433277","https://openalex.org/W2020671379","https://openalex.org/W2032048326","https://openalex.org/W2034075575","https://openalex.org/W2045063779","https://openalex.org/W2045486084","https://openalex.org/W2045642258","https://openalex.org/W2049562411","https://openalex.org/W2051901597","https://openalex.org/W2052555866","https://openalex.org/W2056516126","https://openalex.org/W2058833335","https://openalex.org/W2060240527","https://openalex.org/W2060760516","https://openalex.org/W2061511405","https://openalex.org/W2062016541","https://openalex.org/W2062269191","https://openalex.org/W2062701384","https://openalex.org/W2067644861","https://openalex.org/W2071925677","https://openalex.org/W2073797247","https://openalex.org/W2074948025","https://openalex.org/W2076812730","https://openalex.org/W2079383900","https://openalex.org/W2088381487","https://openalex.org/W2091044388","https://openalex.org/W2097180816","https://openalex.org/W2101940624","https://openalex.org/W2102319322","https://openalex.org/W2105385967","https://openalex.org/W2110380015","https://openalex.org/W2121070541","https://openalex.org/W2126726883","https://openalex.org/W2132256276","https://openalex.org/W2132435179","https://openalex.org/W2132526241","https://openalex.org/W2132737274","https://openalex.org/W2132827179","https://openalex.org/W2134881250","https://openalex.org/W2136175619","https://openalex.org/W2136830554","https://openalex.org/W2138005066","https://openalex.org/W2138195191","https://openalex.org/W2138528245","https://openalex.org/W2144699537","https://openalex.org/W2145437036","https://openalex.org/W2147381220","https://openalex.org/W2147665626","https://openalex.org/W2147717040","https://openalex.org/W2151089147","https://openalex.org/W2153403046","https://openalex.org/W2154847232","https://openalex.org/W2156339957","https://openalex.org/W2158496331","https://openalex.org/W2159815605","https://openalex.org/W2163828960","https://openalex.org/W2165061476","https://openalex.org/W2167550154","https://openalex.org/W2169107043","https://openalex.org/W2171467827","https://openalex.org/W2248059988","https://openalex.org/W2324841714","https://openalex.org/W2337341934","https://openalex.org/W2338441777","https://openalex.org/W2506068387","https://openalex.org/W4292691741"],"related_works":["https://openalex.org/W2790278766","https://openalex.org/W2129978302","https://openalex.org/W2307140082","https://openalex.org/W7095070344","https://openalex.org/W2094741813","https://openalex.org/W1987129577","https://openalex.org/W1981242723","https://openalex.org/W2131153615","https://openalex.org/W2092386362","https://openalex.org/W2970516066"],"abstract_inverted_index":{"Our":[0],"lab":[1],"established":[2],"that":[3,25,114],"moderate":[4],"ethanol":[5,62,69,89,105,129,137],"preconditioning":[6,103],"(MEP)":[7],"for":[8],"6":[9],"days":[10],"blocked":[11],"the":[12,28,32,44,57,93],"A\u00e225-35":[13,66,77,99,144],"toxicity":[14,100],"in":[15,78,96,120],"cerebellar":[16,79],"mixed":[17,80],"cell":[18,45,81,122],"cultures":[19,123],"and":[20,63,70,90,130,138],"It":[21],"has":[22],"been":[23],"shown":[24],"MEP":[26,41],"cause":[27],"up":[29],"regulation":[30],"of":[31,61,85,88,98,128,133,136],"pre-survival":[33],"enzymes":[34],"such":[35],"as":[36],"proxiredoxin2":[37,115],"(PRX2),":[38],"which":[39],"suggests":[40],"can":[42],"activate":[43],"survival":[46],"pathways":[47],"against":[48,65,76,143],"upcoming":[49],"toxins.":[50],"This":[51],"study":[52],"was":[53],"performed":[54],"to":[55,102],"verify":[56],"possible":[58],"combinatory":[59],"effect":[60],"resveratrol":[64,71,91,107,139],"toxicity.":[67,145],"Both":[68],"sub-protective":[72,86,126,134],"concentrations":[73],"were":[74,117],"detected":[75],"cultures.":[82],"The":[83,109],"combination":[84],"levels":[87,116,135],"showed":[92,140],"significantly":[94,119],"reduction":[95],"number":[97],"compare":[101],"with":[104,124],"or":[106],"alone.":[108],"western":[110],"blot":[111],"analysis":[112],"revealed":[113],"increased":[118],"preconditioned":[121],"combined":[125],"level":[127],"resveratrol.":[131],"Combination":[132],"synergistic":[141],"protection":[142]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
