{"id":"https://openalex.org/W110289574","doi":null,"title":"[Antimicrobial resistant test of H. pylori].","display_name":"[Antimicrobial resistant test of H. pylori].","publication_year":2001,"publication_date":"2001-02-01","ids":{"openalex":"https://openalex.org/W110289574","mag":"110289574","pmid":"https://pubmed.ncbi.nlm.nih.gov/11218400"},"language":"ja","primary_location":{"id":"pmid:11218400","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11218400","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon rinsho. Japanese journal of clinical medicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074085528","display_name":"Keiko Inoue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146500386","display_name":"Jichi Medical University","ror":"https://ror.org/010hz0g26","country_code":"JP","type":"education","lineage":["https://openalex.org/I146500386"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K Inoue","raw_affiliation_strings":["Department of Gastroenterology, Jichi Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Jichi Medical School","institution_ids":["https://openalex.org/I146500386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111414339","display_name":"Kaori Satoh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Satoh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005448266","display_name":"Hiroshi Muto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Muto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5038671870","display_name":"Kentaro Sugano","orcid":"https://orcid.org/0000-0002-8578-2974","observed_orcids":["https://orcid.org/0000-0002-8578-2974"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Sugano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2886,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.6110445,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"59","issue":"2","first_page":"291","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":1.0},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.8489999771118164},{"id":"https://openalex.org/keywords/clarithromycin-resistance","display_name":"clarithromycin resistance","score":0.9959999918937683},{"id":"https://openalex.org/keywords/metronidazole-resistance","display_name":"metronidazole resistance","score":0.9369999766349792},{"id":"https://openalex.org/keywords/e-test","display_name":"E-test","score":0.9319999814033508},{"id":"https://openalex.org/keywords/triple-therapy","display_name":"triple therapy","score":0.8180000185966492},{"id":"https://openalex.org/keywords/eradication-therapy","display_name":"eradication therapy","score":0.656000018119812},{"id":"https://openalex.org/keywords/antimicrobial-susceptibility-testing","display_name":"antimicrobial susceptibility testing","score":0.597000002861023}],"concepts":[{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.9179178476333618},{"id":"https://openalex.org/C2780493024","wikidata":"https://www.wikidata.org/wiki/Q19903202","display_name":"Agar dilution","level":4,"score":0.6862640976905823},{"id":"https://openalex.org/C2776962512","wikidata":"https://www.wikidata.org/wiki/Q118551","display_name":"Clarithromycin","level":3,"score":0.6757685542106628},{"id":"https://openalex.org/C40749294","wikidata":"https://www.wikidata.org/wiki/Q4631553","display_name":"23S ribosomal RNA","level":5,"score":0.615123987197876},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.596565842628479},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5182433128356934},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.5035037398338318},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4943537712097168},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.48874855041503906},{"id":"https://openalex.org/C2909292399","wikidata":"https://www.wikidata.org/wiki/Q19903202","display_name":"Agar Dilution Method","level":4,"score":0.45143797993659973},{"id":"https://openalex.org/C176944494","wikidata":"https://www.wikidata.org/wiki/Q1415380","display_name":"Point mutation","level":4,"score":0.42030957341194153},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40734583139419556},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.2507877051830292},{"id":"https://openalex.org/C176947019","wikidata":"https://www.wikidata.org/wiki/Q597889","display_name":"Minimum inhibitory concentration","level":3,"score":0.21846380829811096},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19705471396446228},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10532104969024658},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.047067791223526},{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D004352","descriptor_name":"Drug Resistance, Microbial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008795","descriptor_name":"Metronidazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008795","descriptor_name":"Metronidazole","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012338","descriptor_name":"RNA, Ribosomal, 23S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D017291","descriptor_name":"Clarithromycin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017291","descriptor_name":"Clarithromycin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:11218400","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11218400","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon rinsho. Japanese journal of clinical medicine","raw_type":"Journal Article"},{"id":"mag:110289574","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11218400","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2043141004","https://openalex.org/W2369304342","https://openalex.org/W2059956455","https://openalex.org/W1889281716","https://openalex.org/W13494016","https://openalex.org/W2038965036","https://openalex.org/W2361896422","https://openalex.org/W2109800747","https://openalex.org/W2023842018","https://openalex.org/W2794283165"],"abstract_inverted_index":{"The":[0,59,71],"resistance":[1],"of":[2,31,34,37,41,47,61,69,74],"Helicobacter":[3],"pylori":[4,52,83,93],"(H.":[5],"pylori)":[6],"to":[7,22,101],"antibiotics":[8],"leaves":[9],"great":[10],"influence":[11],"on":[12],"treatment":[13],"outcome.":[14],"Agar":[15],"and":[16,24,86,104],"broth":[17],"dilution":[18],"techniques":[19],"are":[20],"difficult":[21,100],"perform":[23],"not":[25],"practical.":[26],"E-test":[27],"has":[28],"the":[29],"advantage":[30],"allowing":[32],"visualization":[33],"resistant":[35],"subpopulations":[36],"bacteria":[38],"within":[39],"zones":[40],"inhibitions.":[42],"We":[43],"studied":[44],"point":[45],"mutation":[46],"23s-rRNA":[48],"gene":[49],"for":[50,80,90],"H.":[51,82,92,106],"strains.":[53],"(74":[54],"clarithromycin":[55],"(CAM)-resistant,":[56],"6":[57],"CAM-susceptible)":[58],"results":[60],"these":[62,68],"assays":[63],"were":[64],"well":[65],"correlated":[66],"with":[67,77,88],"E-test.":[70],"cure":[72],"rate":[73],"triple":[75],"therapy":[76],"metoronidazole":[78],"(MTZ)":[79],"CAM-resistant":[81],"is":[84,94,98],"100%(11/11),":[85],"that":[87],"CAM":[89,103],"MTZ-resistant":[91,105],"94.4%":[95],"(17/18).":[96],"It":[97],"very":[99],"eradicate":[102],"pylori.":[107]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}