{"id":"https://openalex.org/W1094897","doi":null,"title":"The effects of chronic tea intake on platelet activation and vascular biology: a double-blind placebo controlled trial","display_name":"The effects of chronic tea intake on platelet activation and vascular biology: a double-blind placebo controlled trial","publication_year":2007,"publication_date":"2007-08-01","ids":{"openalex":"https://openalex.org/W1094897","mag":"1094897"},"language":"en","primary_location":{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:3315","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/3315/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Atherosclerosis , 193 (2) pp. 277-282. (2007)","raw_type":"Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005721369","display_name":"Andrew Steptoe","orcid":"https://orcid.org/0000-0001-7808-4943","observed_orcids":["https://orcid.org/0000-0001-7808-4943"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew Steptoe","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7808-4943","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010413232","display_name":"Erika Gibson","orcid":"https://orcid.org/0009-0001-9598-6153","observed_orcids":["https://orcid.org/0009-0001-9598-6153"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erika Gibson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004267510","display_name":"Raisa Vuononvirta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raisa Vuononvirta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040846869","display_name":"Mark Hamer","orcid":"https://orcid.org/0000-0002-8726-7992","observed_orcids":["https://orcid.org/0000-0002-8726-7992"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Hamer","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8726-7992","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026663035","display_name":"Jane Wardle","orcid":"https://orcid.org/0000-0002-1691-593X","observed_orcids":["https://orcid.org/0000-0002-1691-593X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jane Wardle","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073032277","display_name":"Jane A. Rycroft","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jane A. Rycroft","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100879602","display_name":"JF Martin","orcid":"https://orcid.org/0000-0003-4804-8890","observed_orcids":["https://orcid.org/0000-0003-4804-8890"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.F. Martin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058482452","display_name":"Jorge D. Erusalimsky","orcid":"https://orcid.org/0000-0002-4253-5789","observed_orcids":["https://orcid.org/0000-0002-4253-5789"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jorge D. Erusalimsky","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4253-5789","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00027641,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/black-tea","display_name":"black tea","score":0.9110000133514404},{"id":"https://openalex.org/keywords/platelet-activation","display_name":"platelet activation","score":0.847000002861023},{"id":"https://openalex.org/keywords/platelet-leukocyte-aggregates","display_name":"platelet-leukocyte aggregates","score":0.7609999775886536},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9459999799728394},{"id":"https://openalex.org/keywords/soluble-p-selectin","display_name":"soluble P-selectin","score":0.8080000281333923},{"id":"https://openalex.org/keywords/total-antioxidant-status","display_name":"total antioxidant status","score":0.8259999752044678},{"id":"https://openalex.org/keywords/coronary-heart-disease-prevention","display_name":"coronary heart disease prevention","score":0.7279999852180481},{"id":"https://openalex.org/keywords/cardiovascular-health","display_name":"cardiovascular health","score":0.9139999747276306},{"id":"https://openalex.org/keywords/healthy-men","display_name":"healthy men","score":0.4180000126361847}],"concepts":[{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.7641769051551819},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7604677677154541},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.73124098777771},{"id":"https://openalex.org/C3018697912","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Platelet activation","level":3,"score":0.705444872379303},{"id":"https://openalex.org/C2781195455","wikidata":"https://www.wikidata.org/wiki/Q422766","display_name":"C-reactive protein","level":3,"score":0.5565676093101501},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.465177983045578},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4344310760498047},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.4121287763118744},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.26787325739860535},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.12150949239730835},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11677992343902588},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08791789412498474},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:3315","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/3315/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Atherosclerosis , 193 (2) pp. 277-282. (2007)","raw_type":"Article"},{"id":"mag:1094897","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/id/eprint/3315","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1976039425","https://openalex.org/W2119564633","https://openalex.org/W7100059582","https://openalex.org/W2330159460","https://openalex.org/W2146732879","https://openalex.org/W2051404982","https://openalex.org/W2136185152","https://openalex.org/W2117192402","https://openalex.org/W2022934178","https://openalex.org/W246705519"],"abstract_inverted_index":{"Background:":[0],"\\nTea":[1],"drinking":[2],"appears":[3],"to":[4,60,188,200],"protect":[5],"against":[6],"the":[7,15,22,116,155],"development":[8],"of":[9,24,27,97,196],"coronary":[10],"heart":[11],"disease":[12],"(CHD),":[13],"but":[14,86],"mediating":[16],"pathways":[17],"are":[18],"uncertain.":[19],"We":[20],"studied":[21],"effects":[23,195],"6":[25,95],"weeks":[26,96],"black":[28,61],"tea":[29,62,117,172,197],"or":[30,66,83,166,191],"placebo":[31,67,89,156],"on":[32],"platelet":[33,175],"activation,":[34],"C-reactive":[35,144,179],"protein":[36,145,180],"(CRP),":[37],"total":[38,135,163],"antioxidant":[39,164],"status,":[40],"and":[41,141,177],"soluble":[42,167],"(s)":[43],"P-Selectin":[44],"in":[45,162,181],"a":[46,72],"randomized":[47,59],"double-blind":[48],"trial.":[49],"\\n":[50,112,169],"\\nMethods:":[51],"\\nHealthy":[52],"non-smoking":[53],"men":[54],"aged":[55],"18\u201355":[56],"years":[57],"were":[58,92,159],"(N":[63,68],"=":[64,69,128,133,139,152],"37)":[65],"38)":[70],"following":[71],"4-week":[73],"washout":[74],"period":[75],"during":[76],"which":[77],"they":[78],"drank":[79],"no":[80,160],"tea,":[81],"coffee":[82],"caffeinated":[84,88],"beverages,":[85],"consumed":[87],"tea.":[90],"Bloods":[91],"drawn":[93],"after":[94],"treatment.":[98],"Platelet":[99],"activation":[100,176],"was":[101],"assessed":[102],"by":[103],"measuring":[104],"leukocyte\u2013platelet":[105,136],"aggregates":[106,122,131,137],"using":[107],"whole":[108],"blood":[109],"flow":[110],"cytometry.":[111],"\\nResults:":[113],"\\nFollowing":[114],"treatment,":[115],"group":[118],"had":[119],"fewer":[120],"monocyte\u2013platelet":[121],"(means":[123,146],"5.84":[124],"versus":[125,148],"6.60%,":[126],"P":[127,151],"0.027),":[129,140],"neutrophil\u2013platelet":[130],"(P":[132,138],"0.017),":[134],"lower":[142],"plasma":[143,178],"0.76":[147],"0.97":[149],"mg/L,":[150],"0.05)":[153],"than":[154],"group.":[157],"There":[158],"differences":[161],"status":[165],"P-Selectin.":[168],"\\nConclusions:":[170],"\\nChronic":[171],"consumption":[173],"reduces":[174],"healthy":[182],"men.":[183],"Effects":[184],"cannot":[185],"be":[186],"attributed":[187],"observer":[189],"bias":[190],"lifestyle":[192],"confounders.":[193],"These":[194],"may":[198],"contribute":[199],"sustained":[201],"cardiovascular":[202],"health.":[203]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}