{"id":"https://openalex.org/W107455541","doi":null,"title":"IgG-F-actin antibodies in celiac disease and dermatitis herpetiformis.","display_name":"IgG-F-actin antibodies in celiac disease and dermatitis herpetiformis.","publication_year":2010,"publication_date":"2010-10-01","ids":{"openalex":"https://openalex.org/W107455541","mag":"107455541","pmid":"https://pubmed.ncbi.nlm.nih.gov/21462831"},"language":"en","primary_location":{"id":"pmid:21462831","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21462831","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Roumanian archives of microbiology and immunology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057105143","display_name":"Gabriel Sama\u015fc\u0103","orcid":"https://orcid.org/0000-0002-7645-0716","observed_orcids":["https://orcid.org/0000-0002-7645-0716"]},"institutions":[{"id":"https://openalex.org/I208470662","display_name":"Iuliu Ha\u021bieganu University of Medicine and Pharmacy","ror":"https://ror.org/051h0cw83","country_code":"RO","type":"education","lineage":["https://openalex.org/I208470662"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Gabriel Sama\u015fca","raw_affiliation_strings":["Department of Immunology, \"Iuliu Ha\u0163ieganu\" University of Medicine and Pharmacy, Cluj-Napoca, Romania. Gabriel.Samasca@umfcluj.ro"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, \"Iuliu Ha\u0163ieganu\" University of Medicine and Pharmacy, Cluj-Napoca, Romania. Gabriel.Samasca@umfcluj.ro","institution_ids":["https://openalex.org/I208470662"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041578218","display_name":"Adrian Lucian Baican","orcid":"https://orcid.org/0000-0002-4116-6459","observed_orcids":["https://orcid.org/0000-0002-4116-6459"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adrian B\u0103ican","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022839118","display_name":"Tudor Lucian Pop","orcid":"https://orcid.org/0000-0002-4931-1219","observed_orcids":["https://orcid.org/0000-0002-4931-1219"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tudor Pop","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090969767","display_name":"Alexandru P\u00eervan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexandru P\u00eervan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089009304","display_name":"Nicolae Miu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicolae Miu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062268176","display_name":"Mariana Andreica","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mariana Andreica","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110307563","display_name":"Victor Cristea","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Victor Cristea","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5031146961","display_name":"D Dejic\u00e0","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Doru Dejica","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8516,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.76115526,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"69","issue":"4","first_page":"177","last_page":"82"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12538","display_name":"Eosinophilic Esophagitis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10733","display_name":"Wheat and Barley Genetics and Pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/celiac-disease","display_name":"celiac disease","score":0.9039999842643738},{"id":"https://openalex.org/keywords/dermatitis-herpetiformis","display_name":"dermatitis herpetiformis","score":1.0},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.8759999871253967},{"id":"https://openalex.org/keywords/pediatric-celiac-disease","display_name":"pediatric celiac disease","score":0.875},{"id":"https://openalex.org/keywords/gluten-free-diet","display_name":"gluten-free diet","score":0.8420000076293945},{"id":"https://openalex.org/keywords/autoimmune-enteropathy","display_name":"autoimmune enteropathy","score":0.4950000047683716}],"concepts":[{"id":"https://openalex.org/C2778728583","wikidata":"https://www.wikidata.org/wiki/Q1151507","display_name":"Dermatitis herpetiformis","level":3,"score":0.9818754196166992},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7555015087127686},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.673143208026886},{"id":"https://openalex.org/C2780366471","wikidata":"https://www.wikidata.org/wiki/Q1072420","display_name":"Primary biliary cirrhosis","level":2,"score":0.5191799402236938},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.495063453912735},{"id":"https://openalex.org/C178498320","wikidata":"https://www.wikidata.org/wiki/Q14903608","display_name":"Tissue transglutaminase","level":3,"score":0.4823881685733795},{"id":"https://openalex.org/C2993432164","wikidata":"https://www.wikidata.org/wiki/Q868506","display_name":"Villous atrophy","level":4,"score":0.47867709398269653},{"id":"https://openalex.org/C2776029263","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Hepatitis","level":2,"score":0.43131959438323975},{"id":"https://openalex.org/C2776336767","wikidata":"https://www.wikidata.org/wiki/Q188251","display_name":"Gluten","level":2,"score":0.42223218083381653},{"id":"https://openalex.org/C2777203481","wikidata":"https://www.wikidata.org/wiki/Q786844","display_name":"Autoimmune hepatitis","level":3,"score":0.4159248173236847},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4015709161758423},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3928382992744446},{"id":"https://openalex.org/C2780349322","wikidata":"https://www.wikidata.org/wiki/Q11088","display_name":"Coeliac disease","level":3,"score":0.3108718991279602},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24632969498634338},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.16970118880271912},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10124146938323975},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002446","descriptor_name":"Celiac Disease","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003874","descriptor_name":"Dermatitis Herpetiformis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011503","descriptor_name":"Transglutaminases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012383","descriptor_name":"Romania","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":1,"locations":[{"id":"pmid:21462831","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21462831","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Roumanian archives of microbiology and immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":165,"referenced_works":["https://openalex.org/W2070378","https://openalex.org/W19871479","https://openalex.org/W120391560","https://openalex.org/W143913873","https://openalex.org/W198376462","https://openalex.org/W210029225","https://openalex.org/W1540591140","https://openalex.org/W1575585006","https://openalex.org/W1582631423","https://openalex.org/W1661416591","https://openalex.org/W1674079630","https://openalex.org/W1867019379","https://openalex.org/W1893279295","https://openalex.org/W1939125543","https://openalex.org/W1955612312","https://openalex.org/W1967620589","https://openalex.org/W1968274808","https://openalex.org/W1970336778","https://openalex.org/W1971457804","https://openalex.org/W1973029849","https://openalex.org/W1975304425","https://openalex.org/W1975815647","https://openalex.org/W1976284083","https://openalex.org/W1976656293","https://openalex.org/W1981008354","https://openalex.org/W1981709837","https://openalex.org/W1983019708","https://openalex.org/W1984684560","https://openalex.org/W1987520066","https://openalex.org/W1987560620","https://openalex.org/W1987735044","https://openalex.org/W1989925309","https://openalex.org/W1990827391","https://openalex.org/W1991193659","https://openalex.org/W1993539774","https://openalex.org/W1994349104","https://openalex.org/W1995311160","https://openalex.org/W1997058116","https://openalex.org/W1999600031","https://openalex.org/W2002932151","https://openalex.org/W2003561111","https://openalex.org/W2003585821","https://openalex.org/W2003877633","https://openalex.org/W2004708987","https://openalex.org/W2007631222","https://openalex.org/W2010382327","https://openalex.org/W2013146483","https://openalex.org/W2020142073","https://openalex.org/W2023128342","https://openalex.org/W2028145032","https://openalex.org/W2029640857","https://openalex.org/W2030682069","https://openalex.org/W2031468489","https://openalex.org/W2037299986","https://openalex.org/W2037995910","https://openalex.org/W2038976543","https://openalex.org/W2041371533","https://openalex.org/W2044941282","https://openalex.org/W2049372707","https://openalex.org/W2052998574","https://openalex.org/W2057371700","https://openalex.org/W2057549168","https://openalex.org/W2059237476","https://openalex.org/W2060973099","https://openalex.org/W2063105468","https://openalex.org/W2066869952","https://openalex.org/W2068639447","https://openalex.org/W2069648173","https://openalex.org/W2070423314","https://openalex.org/W2072488504","https://openalex.org/W2072799417","https://openalex.org/W2072805667","https://openalex.org/W2072952459","https://openalex.org/W2073332085","https://openalex.org/W2073450677","https://openalex.org/W2073802471","https://openalex.org/W2074150842","https://openalex.org/W2074641515","https://openalex.org/W2075326117","https://openalex.org/W2075617465","https://openalex.org/W2075737026","https://openalex.org/W2077492907","https://openalex.org/W2080721009","https://openalex.org/W2080935386","https://openalex.org/W2081139271","https://openalex.org/W2081360252","https://openalex.org/W2083145206","https://openalex.org/W2084786488","https://openalex.org/W2085852125","https://openalex.org/W2087115630","https://openalex.org/W2089929836","https://openalex.org/W2091271580","https://openalex.org/W2091603456","https://openalex.org/W2093474480","https://openalex.org/W2094778938","https://openalex.org/W2096994712","https://openalex.org/W2100645101","https://openalex.org/W2101014162","https://openalex.org/W2101170125","https://openalex.org/W2101230909","https://openalex.org/W2101365364","https://openalex.org/W2104934636","https://openalex.org/W2105402817","https://openalex.org/W2106685695","https://openalex.org/W2108244474","https://openalex.org/W2110491264","https://openalex.org/W2112982595","https://openalex.org/W2114059045","https://openalex.org/W2116015828","https://openalex.org/W2116378268","https://openalex.org/W2116878856","https://openalex.org/W2117835779","https://openalex.org/W2118029870","https://openalex.org/W2118793193","https://openalex.org/W2118831097","https://openalex.org/W2120010406","https://openalex.org/W2122556781","https://openalex.org/W2123777075","https://openalex.org/W2125328419","https://openalex.org/W2127029141","https://openalex.org/W2127330185","https://openalex.org/W2128211931","https://openalex.org/W2131230616","https://openalex.org/W2131857169","https://openalex.org/W2136338773","https://openalex.org/W2137300622","https://openalex.org/W2142692636","https://openalex.org/W2143366420","https://openalex.org/W2146292204","https://openalex.org/W2146604395","https://openalex.org/W2146986536","https://openalex.org/W2147016467","https://openalex.org/W2150505180","https://openalex.org/W2150906077","https://openalex.org/W2151865733","https://openalex.org/W2152642587","https://openalex.org/W2154424724","https://openalex.org/W2157921582","https://openalex.org/W2158790015","https://openalex.org/W2158921004","https://openalex.org/W2158956822","https://openalex.org/W2159533261","https://openalex.org/W2161030582","https://openalex.org/W2161111013","https://openalex.org/W2163902276","https://openalex.org/W2166282414","https://openalex.org/W2166646646","https://openalex.org/W2167792556","https://openalex.org/W2168071213","https://openalex.org/W2169233545","https://openalex.org/W2170068914","https://openalex.org/W2171065323","https://openalex.org/W2171279050","https://openalex.org/W2171356723","https://openalex.org/W2204506686","https://openalex.org/W2256369611","https://openalex.org/W2281726765","https://openalex.org/W2397237133","https://openalex.org/W2417979456","https://openalex.org/W2424607300","https://openalex.org/W2468014020","https://openalex.org/W2499285607","https://openalex.org/W2772222670","https://openalex.org/W3036092946","https://openalex.org/W4254280253"],"related_works":["https://openalex.org/W2085835493","https://openalex.org/W2127330185","https://openalex.org/W2065009451","https://openalex.org/W7000360863","https://openalex.org/W38668210","https://openalex.org/W2383213181","https://openalex.org/W2944960359","https://openalex.org/W1995430466","https://openalex.org/W2012773318","https://openalex.org/W2092826164"],"abstract_inverted_index":{"Anti-actin":[0],"antibodies":[1,30,68,76,125],"are":[2],"found":[3],"in":[4,16,42,48,86,155,168,182,204,214,223],"52-85%":[5],"of":[6,18,35,56,62,65,134,176,180,186,231],"patients":[7,19,25,107,117,206,216],"with":[8,20,26,32,72,108,118,207,217,233],"autoimmune":[9],"hepatitis":[10,14],"or":[11],"chronic":[12],"active":[13],"and":[15,45,89,92,114,158,178,213],"22%":[17],"primary":[21],"biliary":[22],"cirrhosis.":[23],"In":[24],"celiac":[27,43,87,109,156,208],"disease,":[28],"anti-actin":[29],"correlate":[31],"the":[33,63,132,141,183],"degree":[34],"villous":[36],"atrophy.":[37],"Studies":[38],"on":[39],"their":[40],"involvement":[41],"disease":[44,88,110,157,209],"dermatitis":[46,90,119,169,218],"herpetiformis":[47,91],"Romania":[49],"have":[50],"not":[51,201],"been":[52],"done.":[53],"The":[54,102,123],"purpose":[55],"this":[57],"study":[58,103],"was":[59,173],"to":[60,93,137],"evaluate":[61],"quality":[64],"IgG":[66],"anti-F-actin":[67],"(IgG-AAA)":[69],"tests":[70],"compared":[71,136],"IgA":[73,79],"tissue":[74],"transglutaminase":[75],"(IgA-TgA)":[77],"having":[78],"endomysial":[80],"antibody":[81],"(IgA-EmA)":[82],"as":[83],"gold":[84],"standard":[85],"see":[94],"if":[95],"there":[96,172],"is":[97],"any":[98],"relationship":[99,230],"between":[100],"them.":[101,234],"included":[104],"70":[105],"pediatric":[106],"under":[111,210],"gluten-free":[112,211],"diets":[113,212],"10":[115],"adult":[116,215],"herpetiformis,":[120],"during":[121],"2010.":[122],"IgG-AAA":[124,135,181,199],"levels":[126],"were":[127,193],"determined":[128],"by":[129],"ELISA.":[130],"Assessing":[131],"qualities":[133],"IgA-TgA,":[138],"we":[139,196],"obtained":[140],"following":[142],"values":[143],"sensitivity":[144],"(Se)":[145],"27.8%,":[146],"specificity":[147],"(Sp)":[148],"79.4%,":[149],"respectively":[150,163],"Se":[151,159,164],"88.9%,":[152],"Sp":[153,161,166],"79.4%":[154],"33.3%,":[160],"100%,":[162,165],"100%":[167],"herpetiformis.":[170,219],"Also,":[171],"a":[174,229],"prevalence":[175],"24.3%":[177],"30%":[179],"two":[184],"groups":[185],"patients,":[187],"but":[188,227],"no":[189],"statistically":[190],"significant":[191],"associations":[192],"found.":[194],"Therefore,":[195],"concluded":[197],"that":[198],"can":[200],"replace":[202],"IgA-TgA":[203],"children":[205],"AAA-IgG":[220],"serum":[221],"activity":[222],"both":[224],"diseases":[225],"exist,":[226],"without":[228],"association":[232]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}