{"id":"https://openalex.org/W107263156","doi":null,"title":"Effect of housing rats in dim light or long nights on heart rate.","display_name":"Effect of housing rats in dim light or long nights on heart rate.","publication_year":2008,"publication_date":"2008-07-01","ids":{"openalex":"https://openalex.org/W107263156","mag":"107263156","pmid":"https://pubmed.ncbi.nlm.nih.gov/18702448","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2694710"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2694710","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2694710","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Assoc Lab Anim Sci","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2694710","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038205089","display_name":"Toni A. Azar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Toni A Azar","raw_affiliation_strings":["Department of Physiology, Wayne State University School of Medicine, Detroit, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Wayne State University School of Medicine, Detroit, MI, USA","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079832052","display_name":"Jody L Sharp","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jody L Sharp","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"David M Lawson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David M Lawson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.5583,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.86601568,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"47","issue":"4","first_page":"25","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10838","display_name":"Animal Behavior and Welfare Studies","score":0.6509000062942505,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10838","display_name":"Animal Behavior and Welfare Studies","score":0.6509000062942505,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.2791000008583069,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.023499999195337296,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-night","display_name":"long nights","score":0.7850000262260437},{"id":"https://openalex.org/keywords/resting-heart-rate","display_name":"resting heart rate","score":0.8999999761581421},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3930000066757202},{"id":"https://openalex.org/keywords/spontaneously-hypertensive-rats","display_name":"spontaneously hypertensive rats","score":0.9620000123977661},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.49900001287460327},{"id":"https://openalex.org/keywords/housing-stress","display_name":"housing stress","score":0.42800000309944153},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7129999995231628},{"id":"https://openalex.org/keywords/strain-differences","display_name":"strain differences","score":0.8880000114440918},{"id":"https://openalex.org/keywords/animal-welfare","display_name":"animal welfare","score":0.42500001192092896},{"id":"https://openalex.org/keywords/radio-telemetry","display_name":"radio telemetry","score":0.5460000038146973}],"concepts":[{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.5311340689659119},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5287755727767944},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5148269534111023},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5082287788391113},{"id":"https://openalex.org/C3017965124","wikidata":"https://www.wikidata.org/wiki/Q4929359","display_name":"Blue light","level":2,"score":0.4820705056190491},{"id":"https://openalex.org/C2992067456","wikidata":"https://www.wikidata.org/wiki/Q210064","display_name":"Artificial light","level":3,"score":0.4783605933189392},{"id":"https://openalex.org/C55969652","wikidata":"https://www.wikidata.org/wiki/Q259028","display_name":"photoperiodism","level":2,"score":0.4758731424808502},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.47413110733032227},{"id":"https://openalex.org/C2779027399","wikidata":"https://www.wikidata.org/wiki/Q204170","display_name":"Darkness","level":2,"score":0.4704146683216095},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.416176438331604},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35903310775756836},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3319886326789856},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1096358597278595},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10450947284698486},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.07986265420913696},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C36365805","wikidata":"https://www.wikidata.org/wiki/Q194411","display_name":"Illuminance","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000822","descriptor_name":"Animal Husbandry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006234","descriptor_name":"Handling, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007756","descriptor_name":"Laboratory Animal Science","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008029","descriptor_name":"Lighting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011918","descriptor_name":"Rats, Inbred SHR","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013686","descriptor_name":"Telemetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017440","descriptor_name":"Photoperiod","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2694710","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2694710","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Assoc Lab Anim Sci","raw_type":"Text"},{"id":"pmid:18702448","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18702448","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Association for Laboratory Animal Science : JAALAS","raw_type":"Comparative Study"},{"id":"mag:107263156","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18702448","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2694710","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2694710","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Assoc Lab Anim Sci","raw_type":"Text"},"sustainable_development_goals":[{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W47314421","https://openalex.org/W48309384","https://openalex.org/W84089627","https://openalex.org/W87724286","https://openalex.org/W121753883","https://openalex.org/W151073356","https://openalex.org/W153106834","https://openalex.org/W200719915","https://openalex.org/W1836239441","https://openalex.org/W1965366786","https://openalex.org/W1965777758","https://openalex.org/W1968023975","https://openalex.org/W1969222626","https://openalex.org/W1975068804","https://openalex.org/W1981755144","https://openalex.org/W1983431763","https://openalex.org/W1991410461","https://openalex.org/W1994122020","https://openalex.org/W1997927714","https://openalex.org/W1999146924","https://openalex.org/W2000040971","https://openalex.org/W2005576024","https://openalex.org/W2012134558","https://openalex.org/W2017971332","https://openalex.org/W2020582575","https://openalex.org/W2020595085","https://openalex.org/W2033916592","https://openalex.org/W2037343795","https://openalex.org/W2037355675","https://openalex.org/W2038872972","https://openalex.org/W2044292231","https://openalex.org/W2044352300","https://openalex.org/W2051824012","https://openalex.org/W2052690097","https://openalex.org/W2058879833","https://openalex.org/W2060686160","https://openalex.org/W2061007676","https://openalex.org/W2064119007","https://openalex.org/W2069374405","https://openalex.org/W2072568231","https://openalex.org/W2074796005","https://openalex.org/W2077283632","https://openalex.org/W2078521426","https://openalex.org/W2080156296","https://openalex.org/W2085200167","https://openalex.org/W2087970300","https://openalex.org/W2092406429","https://openalex.org/W2106994691","https://openalex.org/W2107562230","https://openalex.org/W2124712039","https://openalex.org/W2130415523","https://openalex.org/W2136048213","https://openalex.org/W2149446930","https://openalex.org/W2168638573","https://openalex.org/W2175243815","https://openalex.org/W2195045622","https://openalex.org/W2196377790","https://openalex.org/W2210790712","https://openalex.org/W2236080467","https://openalex.org/W2410932980","https://openalex.org/W2413340450","https://openalex.org/W2415287568","https://openalex.org/W2416588412","https://openalex.org/W2474741217","https://openalex.org/W2993729367","https://openalex.org/W2994254594"],"related_works":["https://openalex.org/W638330382","https://openalex.org/W2327724573","https://openalex.org/W2601848052","https://openalex.org/W2035505446","https://openalex.org/W2993729367","https://openalex.org/W7133393039","https://openalex.org/W2335597132","https://openalex.org/W4320473723","https://openalex.org/W4367467423","https://openalex.org/W19626093"],"abstract_inverted_index":{"Housing":[0],"laboratory":[1],"animals":[2],"under":[3,60,72,90,193,207],"lighting":[4],"conditions":[5,214],"that":[6,204,221],"more":[7],"closely":[8],"mimic":[9],"the":[10,20,106,119,125,231],"natural":[11],"environment":[12],"may":[13],"improve":[14],"their":[15,37],"wellbeing.":[16],"This":[17],"study":[18],"examined":[19],"effects":[21,174],"of":[22,34,108,127,173],"dim":[23,145,222],"light":[24,100,146,213,223],"or":[25,71,142,147,197,224],"a":[26,61,91],"long-night":[27],"photocycle":[28,64,76,94],"on":[29],"resting":[30],"heart":[31],"rate":[32],"(HR)":[33],"rats":[35,87,117,135,190,206],"and":[36,44,48,57,101,111,114,121,164,178,181],"HR":[38,107,126,153,186,233],"responses":[39,154,161,166,234],"to":[40,139,155,162,167],"acute":[41,237],"procedures.":[42,170,238],"Male":[43],"female":[45,116,182],"Sprague-Dawley":[46],"(SD)":[47],"spontaneously":[49],"hypertensive":[50],"(SHR)":[51],"rats,":[52],"instrumented":[53],"with":[54,65,77,85,95],"radiotelemetry":[55],"transmitters":[56],"housed":[58,89,192],"individually":[59,88],"12:12-h":[62,92,208],"light:dark":[63,75,93,200],"10":[66,194],"lx":[67,79,97,195,211],"illumination":[68,80,196],"(dim":[69],"light)":[70],"an":[73,198],"8:16-h":[74,199],"200":[78,96,210],"(long":[81],"nights),":[82],"were":[83,136,191],"compared":[84],"control":[86],"illumination.":[98],"Dim":[99],"long":[102,148,225],"nights":[103,149,226],"significantly":[104],"reduced":[105,152,188],"undisturbed":[109,128],"SD":[110,129],"SHR":[112,115],"male":[113,180],"during":[118],"day":[120],"at":[122],"night;":[123],"however,":[124],"females":[130],"was":[131,187,215],"not":[132,159,228],"affected.":[133],"When":[134],"subjected":[137],"acutely":[138],"husbandry,":[140],"experimental,":[141],"stressful":[143],"procedures,":[144,157],"(or":[150],"both)":[151],"some":[156],"did":[158,227],"alter":[160],"others,":[163],"increased":[165,232],"yet":[168],"other":[169],"The":[171],"pattern":[172],"varied":[175],"between":[176,179],"strains":[177],"rats.":[183],"Because":[184],"basal":[185],"when":[189],"photocycle,":[201],"we":[202],"concluded":[203,220],"housing":[205],"light:dark,":[209],"ambient":[212],"potentially":[216],"stressful,":[217],"We":[218],"also":[219],"uniformly":[229],"reduce":[230],"induced":[235],"by":[236]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}