{"id":"https://openalex.org/W10648352","doi":null,"title":"Diagnostic imaging in patients with paragangliomas. Computed tomography, magnetic resonance and MIBG scintigraphy comparison.","display_name":"Diagnostic imaging in patients with paragangliomas. Computed tomography, magnetic resonance and MIBG scintigraphy comparison.","publication_year":1996,"publication_date":"1996-12-01","ids":{"openalex":"https://openalex.org/W10648352","mag":"10648352","pmid":"https://pubmed.ncbi.nlm.nih.gov/9050342"},"language":"en","primary_location":{"id":"pmid:9050342","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9050342","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR)","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054151228","display_name":"Simone Maurea","orcid":"https://orcid.org/0000-0002-8269-3765","observed_orcids":["https://orcid.org/0000-0002-8269-3765"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S Maurea","raw_affiliation_strings":["Medicina Nucleare, Universit\u00e0 degli Studi di Napoli, Federico II, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicina Nucleare, Universit\u00e0 degli Studi di Napoli, Federico II, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075223014","display_name":"Alberto Cuocolo","orcid":"https://orcid.org/0000-0003-3431-7658","observed_orcids":["https://orcid.org/0000-0003-3431-7658"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Cuocolo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108552338","display_name":"James C. Reynolds","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J C Reynolds","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109336300","display_name":"Ronald D. Neumann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R D Neumann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"M Salvatore","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Salvatore","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5226,"has_fulltext":false,"cited_by_count":88,"citation_normalized_percentile":{"value":0.80442213,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"40","issue":"4","first_page":"365","last_page":"71"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11054","display_name":"Adrenal and Paraganglionic Tumors","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11054","display_name":"Adrenal and Paraganglionic Tumors","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paraganglioma","display_name":"paraganglioma","score":0.9850000143051147},{"id":"https://openalex.org/keywords/mibg-scintigraphy","display_name":"MIBG scintigraphy","score":0.9769999980926514},{"id":"https://openalex.org/keywords/131i-mibg","display_name":"131I-MIBG","score":0.9430000185966492},{"id":"https://openalex.org/keywords/computed-tomography","display_name":"computed tomography","score":0.9789999723434448},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"magnetic resonance imaging","score":0.9990000128746033},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.546999990940094},{"id":"https://openalex.org/keywords/benign-versus-malignant-differentiation","display_name":"benign versus malignant differentiation","score":0.652999997138977},{"id":"https://openalex.org/keywords/postoperative-follow-up","display_name":"postoperative follow-up","score":0.8560000061988831},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.7770000100135803},{"id":"https://openalex.org/keywords/extra-adrenal-paraganglioma","display_name":"extra-adrenal paraganglioma","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8614135980606079},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.744889497756958},{"id":"https://openalex.org/C2779902710","wikidata":"https://www.wikidata.org/wiki/Q1130465","display_name":"Scintigraphy","level":2,"score":0.6100397109985352},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.6055322885513306},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5069706439971924},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.4749603271484375},{"id":"https://openalex.org/C2776734335","wikidata":"https://www.wikidata.org/wiki/Q581592","display_name":"Paraganglioma","level":2,"score":0.43752825260162354}],"mesh":[{"descriptor_ui":"D000310","descriptor_name":"Adrenal Gland Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007462","descriptor_name":"Iodobenzenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010235","descriptor_name":"Paraganglioma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010673","descriptor_name":"Pheochromocytoma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019797","descriptor_name":"3-Iodobenzylguanidine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9050342","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9050342","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR)","raw_type":"Comparative Study"},{"id":"mag:10648352","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9050342","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2302317766","https://openalex.org/W2884211131","https://openalex.org/W2019324024","https://openalex.org/W2411368199","https://openalex.org/W4399704531","https://openalex.org/W2981069242","https://openalex.org/W2038439665","https://openalex.org/W3202560956","https://openalex.org/W4205863658","https://openalex.org/W3203030038"],"abstract_inverted_index":{"OBJECTIVE:":[0],"We":[1],"compared":[2,90,101,137,191,261],"iodine-131":[3],"metaiodobenzylguanidine":[4],"(MIBG),":[5],"computed":[6],"tomography":[7],"(CT)":[8],"and":[9,62,76,104,115,128,149,159,165,176,181,204,241],"magnetic":[10],"resonance":[11],"(MR)":[12],"imaging":[13],"studies":[14],"in":[15,41,173,189,209,258],"40":[16],"patients":[17,25,43,69,123,214,228],"with":[18,44,215],"suspected":[19,216],"or":[20,49,232],"proven":[21],"paragangliomas.":[22,39,217],"PATIENTS:":[23],"21":[24],"were":[26,34,65,120,161,171],"studied":[27,70],"during":[28,71,222],"the":[29,72,109,154,210,223],"initial":[30,73,211],"evaluation,":[31,74],"while":[32,238],"19":[33],"evaluated":[35,124],"after":[36,125],"surgery":[37],"for":[38,88,107,118,135,152],"Furthermore,":[40],"18":[42],"benign":[45,180,193,252,263],"(n":[46,51],"=":[47,52],"10)":[48],"malignant":[50,182,190,231,249,259],"8)":[53],"tumors,":[54,183,253],"MIBG":[55,92,95,112,127,141,184,218,254],"uptake,":[56],"MR":[57,77,105,116,129,150,158,174,205,239],"signal":[58],"intensity":[59],"ratios":[60],"(SIR)":[61],"CT":[63,75,103,114,139,148,160,177,203,242],"parameters":[64],"analyzed.":[66],"RESULTS:":[67],"In":[68,122],"had":[78,130],"a":[79,97,266],"significant":[80,169],"(p":[81,195],"<":[82,196],"0.05)":[83],"higher":[84,98,188,257],"diagnostic":[85,267],"sensitivity":[86,133],"(100%":[87],"both)":[89,119,136],"to":[91,102,138,192,247,262,269],"(82%);":[93],"conversely,":[94],"showed":[96,142],"specificity":[99,145],"(100%)":[100,146],"(50%":[106],"both);":[108,153],"accuracy":[110,155],"of":[111,156,213,226],"(86%),":[113],"(91%":[117],"similar.":[121],"surgery,":[126],"slightly":[131],"better":[132,144],"(85%":[134],"(77%).":[140],"again":[143],"than":[147],"(83%":[151],"MIBG,":[157],"respectively":[162],"90%,":[163],"84%":[164],"79%.":[166],"While":[167],"no":[168],"differences":[170],"observed":[172],"SIR":[175,240],"findings":[178],"between":[179],"uptake":[185,255],"was":[186],"significantly":[187],"lesions":[194,260],"0.03).":[197],"CONCLUSIONS:":[198],"Our":[199],"results":[200],"suggest":[201],"that":[202],"are":[206,244],"particularly":[207],"useful":[208],"evaluation":[212],"should":[219],"be":[220],"recommended":[221],"post-surgical":[224],"follow-up":[225],"such":[227],"since":[229],"recurrent,":[230],"extra-adrenal":[233],"disease":[234],"frequently":[235],"occur.":[236],"Finally,":[237],"features":[243],"not":[245],"able":[246],"distinguish":[248],"paragangliomas":[250],"from":[251],"is":[256],"tumors":[264],"providing":[265],"criterion":[268],"differentiate":[270],"these":[271],"lesions.":[272]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}