{"id":"https://openalex.org/W10606457","doi":null,"title":"The Characterization of Campylobacter jejuni Respiratory Oxidases and Reductases and their Role in Host Colonization","display_name":"The Characterization of Campylobacter jejuni Respiratory Oxidases and Reductases and their Role in Host Colonization","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W10606457","mag":"10606457"},"language":"en","primary_location":{"id":"pmh:oai:repository.lib.ncsu.edu:1840.16/4062","doi":null,"is_oa":true,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.16/4062","pdf_url":"http://www.lib.ncsu.edu/resolver/1840.16/4062","source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://www.lib.ncsu.edu/resolver/1840.16/4062","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078489215","display_name":"Rebecca A. Weingarten","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rebecca A. Weingarten","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5078489215"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00171988,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/campylobacter-jejuni","display_name":"Campylobacter jejuni","score":0.9990000128746033},{"id":"https://openalex.org/keywords/electron-transport-chain","display_name":"electron transport chain","score":0.6840000152587891},{"id":"https://openalex.org/keywords/anaerobic-respiration","display_name":"anaerobic respiration","score":0.8320000171661377},{"id":"https://openalex.org/keywords/nitrate-reductase","display_name":"nitrate reductase","score":0.824999988079071},{"id":"https://openalex.org/keywords/nitrite-reductase","display_name":"nitrite reductase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/fumarate-reductase","display_name":"fumarate reductase","score":0.8880000114440918},{"id":"https://openalex.org/keywords/succinate-dehydrogenase","display_name":"succinate dehydrogenase","score":0.9860000014305115},{"id":"https://openalex.org/keywords/alternative-electron-acceptors","display_name":"alternative electron acceptors","score":0.8650000095367432},{"id":"https://openalex.org/keywords/host-colonization","display_name":"host colonization","score":0.640999972820282},{"id":"https://openalex.org/keywords/poultry","display_name":"poultry","score":0.8820000290870667},{"id":"https://openalex.org/keywords/microaerobic-growth","display_name":"microaerobic growth","score":0.6740000247955322},{"id":"https://openalex.org/keywords/campylobacteriosis","display_name":"campylobacteriosis","score":0.671999990940094}],"concepts":[{"id":"https://openalex.org/C2776957140","wikidata":"https://www.wikidata.org/wiki/Q265488","display_name":"Campylobacter jejuni","level":3,"score":0.8919456005096436},{"id":"https://openalex.org/C2776927270","wikidata":"https://www.wikidata.org/wiki/Q815962","display_name":"Colonization","level":2,"score":0.8084392547607422},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.6175414323806763},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6152275800704956},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4965437054634094},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.23628833889961243},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.15987160801887512},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11277827620506287}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:repository.lib.ncsu.edu:1840.16/4062","doi":null,"is_oa":true,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.16/4062","pdf_url":"http://www.lib.ncsu.edu/resolver/1840.16/4062","source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:10606457","doi":null,"is_oa":false,"landing_page_url":"http://europepmc.org/theses/ETH/3247","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repository.lib.ncsu.edu:1840.16/4062","doi":null,"is_oa":true,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.16/4062","pdf_url":"http://www.lib.ncsu.edu/resolver/1840.16/4062","source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320310013","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W10606457.pdf","grobid_xml":"https://content.openalex.org/works/W10606457.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2281260655","https://openalex.org/W2135878201","https://openalex.org/W2523355284","https://openalex.org/W6889674871","https://openalex.org/W2528062414","https://openalex.org/W2530200828","https://openalex.org/W3145740342","https://openalex.org/W7033783183","https://openalex.org/W3163588149","https://openalex.org/W2522802263"],"abstract_inverted_index":{"Campylobacter":[0],"jejuni":[1,14,42,50,72,133,318],"is":[2,15,43,62,128,134,162,310],"a":[3,16,55,211,250,261],"foodborne":[4],"human":[5],"pathogen":[6],"responsible":[7],"for":[8,64,168,197,272],"the":[9,20,26,37,44,58,67,78,88,97,173,194,216,246,254,303,311],"gastroenteritis":[10],"disease,":[11],"campylobacteriosis.":[12],"C.":[13,41,49,71,132,169,317],"commensal":[17],"microorganism":[18],"in":[19,94,150,155,215,294,320,323],"digestive":[21],"tract":[22],"of":[23,28,40,47,60,70,96,193],"birds":[24],"and":[25,57,116,143,203,209,235,267,279,289,322],"majority":[27],"campylobacteriosis":[29],"cases":[30],"are":[31,153],"linked":[32],"to":[33,80,86,136,172,190,224,238,275,283,301,316],"poultry":[34],"products.":[35],"Although":[36],"natural":[38],"habitat":[39],"anaerobic":[45,82],"ceca":[46],"birds,":[48],"has":[51],"long":[52],"been":[53],"considered":[54],"microaerophile":[56],"requirement":[59],"oxygen":[61,130,309],"mandatory":[63],"growth.":[65],"Surprisingly,":[66],"genome":[68],"sequence":[69],"contains":[73],"genes":[74],"that":[75,245,308],"should":[76],"allow":[77],"bacterium":[79],"utilize":[81,191],"respiration.":[83,241],"In":[84],"order":[85],"characterize":[87],"respiratory":[89,262,314],"chain,":[90],"mutants":[91,122,149],"were":[92,270,291],"constructed":[93,214],"each":[95,151],"following":[98],"enzymes:":[99],"nitrate":[100],"reductase":[101,104,108,118,202,226,252],"(napA::Cm),":[102],"nitrite":[103],"(nrfA::Cm),":[105],"SN":[106],"oxide":[107],"(Cj0264c::Cm),":[109],"cbb3-terminal":[110],"oxidase":[111,114,121],"(ccoN::Cm),":[112],"bd-terminal":[113],"(cydA::Cm),":[115],"fumarate":[117,201,208,225,251],"(frdA::Cm).":[119],"Both":[120,220],"grow":[123,137],"on":[124,157],"plates,":[125],"but":[126],"ccoN::Cm":[127,297],"extremely":[129],"sensitive.":[131],"able":[135,189],"anaerobically":[138],"utilizing":[139],"nitrate,":[140],"nitrite,":[141],"DMSO":[142],"TMAO":[144],"as":[145,249,260],"alternative":[146,165],"electron":[147,166,263],"acceptors;":[148],"enzyme":[152,247],"deficient":[154,293],"growth":[156,181],"their":[158,273],"respective":[159],"substrates.":[160],"Fumarate":[161],"not":[163],"an":[164,179],"acceptor":[167,315],"jejuni.":[170],"Compared":[171],"wild":[174,284],"type":[175,266],"strain,":[176],"frdA::Cm":[177,229],"had":[178,230],"affected":[180],"phenotype":[182],"under":[183],"microaerobic":[184],"conditions;":[185],"it":[186],"was":[187,213,236,243,253,298],"only":[188],"half":[192],"TCA":[195],"intermediates":[196],"biomass.":[198],"Because":[199],"both":[200,319],"succinate":[204,217,232,256],"dehydrogenase":[205,218,233],"can":[206],"interconvert":[207],"succinate,":[210],"mutant":[212,268],"(sdhA::Cm).":[219],"enzymes":[221],"equally":[222],"contribute":[223],"activity;":[227],"however,":[228],"no":[231],"activity":[234],"unable":[237,300],"perform":[239],"succinate-dependent":[240],"It":[242],"concluded":[244,307],"annotated":[248],"sole":[255],"dehydrogenase,":[257],"which":[258],"acts":[259],"donor.":[264],"Wild":[265],"strains":[269],"assessed":[271],"ability":[274],"colonize":[276,302],"poultry.":[277],"cydA::Cm":[278],"Cj0264c::Cm":[280],"colonized":[281],"similarly":[282],"type,":[285],"while":[286],"frdA::Cm,":[287],"napA::Cm,":[288],"nrfA::Cm":[290],"significantly":[292],"colonization":[295],"ability.":[296],"completely":[299],"avian":[304],"host.":[305],"We":[306],"most":[312],"important":[313],"vitro":[321],"vivo.":[324]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}