{"id":"https://openalex.org/W105050403","doi":null,"title":"Low miR-34a and miR-192 are associated with unfavorable prognosis in patients suffering from osteosarcoma.","display_name":"Low miR-34a and miR-192 are associated with unfavorable prognosis in patients suffering from osteosarcoma.","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W105050403","mag":"105050403","pmid":"https://pubmed.ncbi.nlm.nih.gov/25755833","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346528"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:3319149","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346528","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346528","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Yuan Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Wang","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lian-Shun Jia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lian-Shun Jia","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059667427","display_name":"Wen Yuan","orcid":"https://orcid.org/0000-0001-9586-1601","observed_orcids":["https://orcid.org/0000-0001-9586-1601"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen Yuan","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038510476","display_name":"Weihong Zhao","orcid":"https://orcid.org/0000-0002-9645-7499","observed_orcids":["https://orcid.org/0000-0002-9645-7499"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao Wu","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hai-Bo Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hai-Bo Wang","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tao Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tao Xu","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085787450","display_name":"Jingchuan Sun","orcid":"https://orcid.org/0000-0002-8956-9409","observed_orcids":["https://orcid.org/0000-0002-8956-9409"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing-Chuan Sun","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ke-Fu Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ke-Fu Cheng","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]},{"author_position":"last","author":{"id":null,"display_name":"Jian-Gang Shi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian-Gang Shi","raw_affiliation_strings":["Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University Shanghai 200003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shanghai Changzheng Hospital, Second Military Medical University Shanghai 200003, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210099558"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6258,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.94406121,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"111","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.019899999722838402,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteosarcoma","display_name":"osteosarcoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mir-34a","display_name":"miR-34a","score":0.9670000076293945},{"id":"https://openalex.org/keywords/mir-192","display_name":"miR-192","score":1.0},{"id":"https://openalex.org/keywords/mir-34-family","display_name":"miR-34 family","score":0.7960000038146973},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.7770000100135803},{"id":"https://openalex.org/keywords/microrna-expression","display_name":"microRNA expression","score":0.7269999980926514},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8880000114440918},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.9890000224113464},{"id":"https://openalex.org/keywords/mir-31","display_name":"miR-31","score":0.9049999713897705},{"id":"https://openalex.org/keywords/mir-215","display_name":"miR-215","score":0.9819999933242798},{"id":"https://openalex.org/keywords/p53-signaling-pathway","display_name":"p53 pathway","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C2777760704","wikidata":"https://www.wikidata.org/wiki/Q549534","display_name":"Osteosarcoma","level":2,"score":0.8919269442558289},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.8546665906906128},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5943268537521362},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5937755703926086},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5426029562950134},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.4795520007610321},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4701780378818512},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44892215728759766},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.44364655017852783},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4273895025253296},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3382098972797394},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3280453085899353},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.15436917543411255},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11495745182037354}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:europepmc.org:3319149","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346528","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4346528","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346528","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},{"id":"pmid:25755833","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25755833","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3319149","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4346528","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W181426613","https://openalex.org/W1250740847","https://openalex.org/W1523828285","https://openalex.org/W1829039191","https://openalex.org/W1856564249","https://openalex.org/W1970431885","https://openalex.org/W1984208675","https://openalex.org/W1993916353","https://openalex.org/W1996543107","https://openalex.org/W2017422522","https://openalex.org/W2036814359","https://openalex.org/W2067529935","https://openalex.org/W2069266255","https://openalex.org/W2070765029","https://openalex.org/W2076526862","https://openalex.org/W2080489168","https://openalex.org/W2082114702","https://openalex.org/W2087110580","https://openalex.org/W2087126635","https://openalex.org/W2090371957","https://openalex.org/W2092658747","https://openalex.org/W2098062497","https://openalex.org/W2112778582","https://openalex.org/W2120307929","https://openalex.org/W2134548024","https://openalex.org/W2146483998","https://openalex.org/W2148077417","https://openalex.org/W2148734673","https://openalex.org/W2149954427","https://openalex.org/W2155070855","https://openalex.org/W2163132442","https://openalex.org/W2168290712","https://openalex.org/W2169285200"],"related_works":["https://openalex.org/W2589858998","https://openalex.org/W2553639003","https://openalex.org/W2180906782","https://openalex.org/W2095288245","https://openalex.org/W2566969081","https://openalex.org/W2999290771","https://openalex.org/W2140910532","https://openalex.org/W3139032822","https://openalex.org/W2784941219","https://openalex.org/W2732863382"],"abstract_inverted_index":{"BACKGROUND:":[0],"p53":[1,22,31,92,137,188,217],"is":[2],"a":[3],"well-known":[4],"tumor":[5,125],"suppressor":[6],"gene":[7],"involved":[8],"in":[9,32,42,62,124,134],"malignancy.":[10],"Many":[11],"microRNAs":[12],"(miRNAs)":[13],"have":[14],"recently":[15],"been":[16],"identified":[17,196],"as":[18],"key":[19],"components":[20],"of":[21,30,47,65,86,96,119,184,203,213,222],"signaling":[23],"networks,":[24],"owing":[25],"to":[26],"the":[27,84,117,182,193,201,211],"central":[28],"role":[29,41],"many":[33],"processes,":[34],"these":[35,227],"p53-regulated":[36],"miRNAs":[37,50,87],"may":[38],"possess":[39],"important":[40],"osteosarcoma.":[43,244],"METHODS:":[44],"The":[45],"expression":[46,88,139,160,179,190,208,235],"six":[48,106],"p53-related":[49],"(miR-34":[51],"family":[52],"[including":[53],"miR-34a,":[54],"34b":[55],"and":[56,60,67,83,94,111,132,157,177,181,206,210,233],"34c],":[57],"miR-31,":[58],"miR-192,":[59],"miR-215)":[61],"80":[63],"pairs":[64],"osteosarcoma":[66,151],"corresponding":[68,128],"noncancerous":[69,129],"bone":[70,130],"tissues":[71],"were":[72,98,219],"estimated":[73],"by":[74],"real-time":[75],"quantitative":[76],"reverse":[77],"transcription":[78],"polymerase":[79],"chain":[80],"reaction":[81],"(RT-qPCR),":[82],"associations":[85],"with":[89,127,136,144,153,174,187,216],"clinicopathological":[90],"factors,":[91],"status,":[93],"survival":[95,164,168],"patients":[97,135,152,173],"analyzed.":[99],"RESULTS:":[100],"We":[101],"found":[102],"that":[103,150,197,230],"among":[104],"all":[105],"miRNAs,":[107],"miR-34":[108],"family,":[109],"-192,":[110],"-215":[112],"had":[113,161],"decreased":[114],"levels,":[115],"whereas":[116],"level":[118],"miR-31":[120],"was":[121,140,170],"increased":[122],"(p<0.05)":[123],"compared":[126],"tissues,":[131],"miR-192/215":[133],"positive":[138,189,218],"lower":[141],"than":[142],"those":[143],"negative":[145],"p53.":[146],"Kaplan-Meier":[147],"analysis":[148,195],"demonstrated":[149],"low":[154,175,185,198,204,214],"miR-34a":[155,176,199,205,232],"(P=0.000)":[156],"miR-192":[158,178,186,207,215,234],"(P=0.022)":[159],"poorer":[162],"disease-free":[163,167],"(DFS).":[165],"Moreover,":[166],"(DFS)":[169],"shorter":[171,223],"for":[172,241],"(P=0.007)":[180],"combination":[183,202,212],"(P=0.000).":[191],"Furthermore,":[192],"multivariate":[194],"expression,":[200],"levels":[209],"independent":[220],"biomarkers":[221,240],"DFS.":[224],"CONCLUSIONS:":[225],"Together,":[226],"results":[228],"suggest":[229],"p53-associated":[231],"could":[236],"be":[237],"novel":[238],"prognosis":[239],"surgically":[242],"treated":[243]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":6}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2025-10-10T00:00:00"}