{"id":"https://openalex.org/W10422884","doi":null,"title":"Prophylactic cefazolin in gastric bypass surgery.","display_name":"Prophylactic cefazolin in gastric bypass surgery.","publication_year":1981,"publication_date":"1981-08-01","ids":{"openalex":"https://openalex.org/W10422884","mag":"10422884","pmid":"https://pubmed.ncbi.nlm.nih.gov/7020141"},"language":"en","primary_location":{"id":"pmid:7020141","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7020141","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006705762","display_name":"Walter J. Pories","orcid":"https://orcid.org/0000-0002-5768-7507","observed_orcids":["https://orcid.org/0000-0002-5768-7507"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W J Pories","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050475981","display_name":"Andr\u00e9 M. van Rij","orcid":"https://orcid.org/0000-0001-5436-2291","observed_orcids":["https://orcid.org/0000-0001-5436-2291"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A M van Rij","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079527257","display_name":"B T Burlingham","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B T Burlingham","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008760113","display_name":"R S Fulghum","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R S Fulghum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5031418271","display_name":"Diane Meelheim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Meelheim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.5348,"has_fulltext":false,"cited_by_count":64,"citation_normalized_percentile":{"value":0.95806954,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"90","issue":"2","first_page":"426","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11080","display_name":"Surgical site infection prevention","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10569","display_name":"Bariatric Surgery and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cefazolin","display_name":"cefazolin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/antibiotic-prophylaxis","display_name":"antibiotic prophylaxis","score":0.9729999899864197},{"id":"https://openalex.org/keywords/gastric-bypass","display_name":"gastric bypass","score":0.9520000219345093},{"id":"https://openalex.org/keywords/morbid-obesity","display_name":"morbid obesity","score":0.9739999771118164},{"id":"https://openalex.org/keywords/surgical-site-infection","display_name":"surgical site infection","score":0.7990000247955322},{"id":"https://openalex.org/keywords/postoperative-infection","display_name":"postoperative infection","score":0.7419999837875366},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.9380000233650208},{"id":"https://openalex.org/keywords/pulmonary-infection","display_name":"pulmonary infection","score":0.9589999914169312},{"id":"https://openalex.org/keywords/perioperative-antibiotics","display_name":"perioperative antibiotics","score":0.75}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9656069874763489},{"id":"https://openalex.org/C2778353156","wikidata":"https://www.wikidata.org/wiki/Q415739","display_name":"Cefazolin","level":3,"score":0.9591102600097656},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.7162052392959595},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.6723573207855225},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5766928195953369},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5736459493637085},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.519224226474762},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4766165316104889},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.46271368861198425},{"id":"https://openalex.org/C2778300832","wikidata":"https://www.wikidata.org/wiki/Q1589604","display_name":"Premedication","level":2,"score":0.4526805281639099},{"id":"https://openalex.org/C2778602436","wikidata":"https://www.wikidata.org/wiki/Q4774943","display_name":"Antibiotic prophylaxis","level":3,"score":0.44763362407684326},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D002437","descriptor_name":"Cefazolin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D011300","descriptor_name":"Preoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:7020141","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7020141","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Clinical Trial"},{"id":"mag:10422884","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7020141","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1608444013","https://openalex.org/W4250000742","https://openalex.org/W2009948417","https://openalex.org/W2170482131","https://openalex.org/W2091239517","https://openalex.org/W2401057257","https://openalex.org/W2396180101","https://openalex.org/W1973502881","https://openalex.org/W2509887586","https://openalex.org/W2415515079"],"abstract_inverted_index":{"Because":[0],"surgery":[1,46],"in":[2,38,100,154,204,222,237,265],"obese":[3],"patients":[4,41,51,119],"is":[5],"associated":[6],"with":[7],"a":[8,28,150,238],"high":[9],"risk":[10],"of":[11,24,32,70,87,106,127,157,164,169,183,199,210,213,240],"infection,":[12],"gastric":[13,44,216],"bypass":[14,45,217],"procedures":[15,218],"offer":[16],"an":[17,84],"excellent":[18],"opportunity":[19],"to":[20,54,66,149,174,191,234,247,252,256],"test":[21,206],"the":[22,101,137,158,167,181,205,245,249],"efficacy":[23],"prophylactic":[25,33,211,232,253],"antibiotics.":[26],"Accordingly,":[27],"double-blind":[29],"prospective":[30],"trial":[31],"cefazolin":[34,59,165,214],"was":[35,134,142],"carried":[36],"out":[37],"53":[39],"consecutive":[40],"who":[42],"underwent":[43],"for":[47,79,122,215],"morbid":[48],"obesity.":[49],"The":[50,132,160,208],"were":[52,95,108,120,147],"randomized":[53],"two":[55],"treatment":[56],"arms:":[57],"(1)":[58],"intravenously,":[60],"1":[61],"gm":[62,75],"2":[63],"hours":[64,78],"prior":[65],"surgery,":[67,118],"at":[68,90,97],"induction":[69],"anesthesia,":[71],"and":[72,99,113,136,180,186,255],"then":[73],"0.5":[74],"every":[76],"6":[77],"48":[80],"hours,":[81],"or":[82],"(2)":[83],"indistinguishable":[85],"placebo":[86],"5%":[88],"dextrose":[89],"identical":[91],"intervals.":[92],"Serial":[93],"cultures":[94],"taken":[96],"operation":[98],"postoperative":[102],"period.":[103],"Antibiotic":[104],"levels":[105,198],"fat":[107],"measured":[109],"by":[110,124],"tissue":[111],"extraction":[112],"B.":[114],"subtilis":[115],"assay.":[116],"After":[117],"monitored":[121],"infection":[123,171],"clinicians":[125],"unaware":[126],"their":[128],"random":[129],"assignment":[130],"group.":[131],"study":[133],"terminated":[135],"code":[138],"broken":[139],"when":[140],"it":[141],"evident":[143],"that":[144],"wound":[145,170],"infections":[146,188],"increased":[148],"statistically":[151],"significant":[152],"difference":[153],"one":[155],"arm":[156],"study.":[159,224],"brief":[161],"perioperative":[162,259],"administration":[163,212],"reduced":[166],"incidence":[168,182],"from":[172,189],"21%":[173],"4%":[175],"(P":[176,193],"less":[177,194],"than":[178,195],"0.05)":[179],"urinary":[184],"tract":[185],"pulmonary":[187],"17%":[190],"0%":[192],"0.05).":[196],"Tissue":[197],"antibiotics":[200,233,254,260],"confirmed":[201],"adequate":[202],"dosages":[203],"subjects.":[207],"advantages":[209],"are":[219],"clearly":[220],"demonstrated":[221],"this":[223],"This":[225],"confirms":[226],"other":[227],"reports":[228],"which":[229],"have":[230],"shown":[231],"be":[235,262],"useful":[236],"variety":[239],"procedures.":[241],"These":[242],"studies":[243],"suggest":[244],"need":[246],"reconsider":[248],"traditional":[250],"opposition":[251],"determine":[257],"whether":[258],"should":[261],"used":[263],"routinely":[264],"all":[266],"major":[267],"operations.":[268]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}