{"id":"https://openalex.org/W103437044","doi":null,"title":"A Closed-Loop Deep Brain Stimulation Device With a Logarithmic Pipeline ADC.","display_name":"A Closed-Loop Deep Brain Stimulation Device With a Logarithmic Pipeline ADC.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W103437044","mag":"103437044"},"language":"en","primary_location":{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/60733","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/60733","pdf_url":"https://hdl.handle.net/2027.42/60733","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/2027.42/60733","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004089240","display_name":"Jongwoo Lee","orcid":"https://orcid.org/0000-0002-3434-0121","observed_orcids":["https://orcid.org/0000-0002-3434-0121"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jongwoo Lee","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3434-0121","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5004089240"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10323","display_name":"Analog and Mixed-Signal Circuit Design","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10323","display_name":"Analog and Mixed-Signal Circuit Design","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Deep Brain Stimulation and Movement Disorders","score":0.10220000147819519,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/closed-loop-deep-brain-stimulation","display_name":"closed-loop deep brain stimulation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/subthalamic-nucleus","display_name":"subthalamic nucleus","score":0.7599999904632568},{"id":"https://openalex.org/keywords/neural-amplifier","display_name":"neural amplifier","score":0.7459999918937683},{"id":"https://openalex.org/keywords/current-steering-dac","display_name":"current-steering DAC","score":0.7770000100135803},{"id":"https://openalex.org/keywords/neural-spike-detection","display_name":"neural spike detection","score":0.5630000233650208},{"id":"https://openalex.org/keywords/implantable-neural-recording","display_name":"implantable neural recording","score":0.6949999928474426},{"id":"https://openalex.org/keywords/principal-component-analysis","display_name":"principal component analysis","score":0.9129999876022339},{"id":"https://openalex.org/keywords/low-power-integrated-circuits","display_name":"low-power integrated circuits","score":0.47699999809265137},{"id":"https://openalex.org/keywords/in-vivo-neural-recording","display_name":"in vivo neural recording","score":0.5149999856948853}],"concepts":[{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.6658609509468079},{"id":"https://openalex.org/C39927690","wikidata":"https://www.wikidata.org/wiki/Q11197","display_name":"Logarithm","level":2,"score":0.6345162987709045},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.5834267735481262},{"id":"https://openalex.org/C3019251811","wikidata":"https://www.wikidata.org/wiki/Q5135346","display_name":"Closed loop","level":2,"score":0.5757913589477539},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5110186338424683},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40182602405548096},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.301614910364151},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.28056037425994873},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.16170600056648254},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.14625349640846252},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13759851455688477},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.12033456563949585},{"id":"https://openalex.org/C133731056","wikidata":"https://www.wikidata.org/wiki/Q4917288","display_name":"Control engineering","level":1,"score":0.10609400272369385},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.09496793150901794},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08736273646354675},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/60733","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/60733","pdf_url":"https://hdl.handle.net/2027.42/60733","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1021.982","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1021.982","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://deepblue.lib.umich.edu/bitstream/handle/2027.42/60733/milaca_1.pdf%3Bjsessionid%3D0199CCFB0AFDE45372AFE1F1497CC27A?sequence%3D1","raw_type":"text"},{"id":"mag:103437044","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/60733","pdf_url":null,"source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Deep Blue (University of Michigan)","raw_type":null}],"best_oa_location":{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/60733","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/60733","pdf_url":"https://hdl.handle.net/2027.42/60733","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310822","display_name":"Catalyst Foundation","ror":"https://ror.org/012jwf593"},{"id":"https://openalex.org/F4320332195","display_name":"Samsung","ror":"https://ror.org/04w3jy968"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W103437044.pdf","grobid_xml":"https://content.openalex.org/works/W103437044.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W20586221","https://openalex.org/W1039793373","https://openalex.org/W1499460360","https://openalex.org/W1517689994","https://openalex.org/W1536945048","https://openalex.org/W1560200935","https://openalex.org/W1564201208","https://openalex.org/W1674977024","https://openalex.org/W1788281108","https://openalex.org/W1831098733","https://openalex.org/W1966132736","https://openalex.org/W1966617461","https://openalex.org/W1967701192","https://openalex.org/W1970924588","https://openalex.org/W1974338262","https://openalex.org/W1975118873","https://openalex.org/W1996291059","https://openalex.org/W1999087799","https://openalex.org/W2003311156","https://openalex.org/W2006412030","https://openalex.org/W2007937858","https://openalex.org/W2016913550","https://openalex.org/W2029522319","https://openalex.org/W2033845134","https://openalex.org/W2040897011","https://openalex.org/W2040996230","https://openalex.org/W2047283250","https://openalex.org/W2056876741","https://openalex.org/W2062865989","https://openalex.org/W2065833894","https://openalex.org/W2074616189","https://openalex.org/W2079557092","https://openalex.org/W2081855094","https://openalex.org/W2087901757","https://openalex.org/W2090662556","https://openalex.org/W2100282901","https://openalex.org/W2101556294","https://openalex.org/W2101741048","https://openalex.org/W2101895727","https://openalex.org/W2103399773","https://openalex.org/W2107635023","https://openalex.org/W2107738534","https://openalex.org/W2109178509","https://openalex.org/W2111563599","https://openalex.org/W2111937020","https://openalex.org/W2112611349","https://openalex.org/W2116353065","https://openalex.org/W2118210921","https://openalex.org/W2123716779","https://openalex.org/W2126868221","https://openalex.org/W2136248087","https://openalex.org/W2136377989","https://openalex.org/W2138060015","https://openalex.org/W2138208292","https://openalex.org/W2138531353","https://openalex.org/W2143126434","https://openalex.org/W2143703270","https://openalex.org/W2145583813","https://openalex.org/W2147652535","https://openalex.org/W2148281748","https://openalex.org/W2148352592","https://openalex.org/W2149638288","https://openalex.org/W2150538259","https://openalex.org/W2152434001","https://openalex.org/W2154488179","https://openalex.org/W2157472016","https://openalex.org/W2163198209","https://openalex.org/W2163486232","https://openalex.org/W2164072701","https://openalex.org/W2165412438","https://openalex.org/W2172139367","https://openalex.org/W2177464813","https://openalex.org/W2237468501","https://openalex.org/W2328435466","https://openalex.org/W2538593453","https://openalex.org/W2540908517","https://openalex.org/W2546716407","https://openalex.org/W2771198110"],"related_works":["https://openalex.org/W391985485","https://openalex.org/W2008917039","https://openalex.org/W2165412438","https://openalex.org/W2176438391","https://openalex.org/W4280621860","https://openalex.org/W4408423692","https://openalex.org/W4400845265","https://openalex.org/W977258166","https://openalex.org/W2535332438","https://openalex.org/W4390188304"],"abstract_inverted_index":{"This":[0],"dissertation":[1],"is":[2,21,44,69,143],"a":[3,22,61,70,96,124,138,208,211,277],"summary":[4],"of":[5,16,25,46,51,78,87,168,210,268,305,328],"the":[6,26,37,47,56,99,156,159,177,185,197,232,245,326,329],"research":[7],"on":[8],"integrated":[9],"closed-loop":[10,72],"deep":[11],"brain":[12],"stimulation":[13,88,193],"for":[14,158,333],"treatment":[15],"Parkinson\u2019s":[17,52],"disease.":[18],"Parkinson's":[19],"disease":[20],"progressive":[23],"disorder":[24],"central":[27],"nervous":[28],"system":[29,101],"affecting":[30],"more":[31,103],"than":[32,90],"three":[33],"million":[34],"people":[35],"in":[36,255],"United":[38],"States.":[39],"Deep":[40],"Brain":[41],"Stimulation":[42],"(DBS)":[43],"one":[45],"most":[48],"effective":[49],"treatments":[50],"symptoms.":[53],"DBS":[54,73],"excites":[55],"Subthalamic":[57],"Nucleus":[58],"(STN)":[59],"with":[60,91,244,290,323],"high":[62,139],"frequency":[63,179],"electrical":[64],"signal.":[65],"The":[66,151,202,225,260,283,299,317],"proposed":[67],"device":[68,247,332],"single-chip":[71],"(CDBS)":[74],"system.":[75],"Closed-loop":[76],"feedback":[77],"sensed":[79],"neural":[80,118,180,186,240,266,281,285,315,319,336],"activity":[81,241],"promises":[82],"better":[83],"control":[84,149,196],"and":[85,109,135,162,218,294],"optimization":[86],"parameters":[89],"open-loop":[92],"devices.":[93],"Thanks":[94],"to":[95,112,123,195,236,249,334],"novel":[97],"architecture,":[98],"prototype":[100,246],"incorporates":[102],"functionality":[104],"yet":[105],"consumes":[106],"less":[107],"power":[108,136],"area":[110,134,230],"compared":[111],"other":[113],"systems.":[114],"Eight":[115],"front-end":[116],"low-noise":[117],"amplifiers":[119],"(LNAs)":[120],"are":[121,205],"multiplexed":[122],"single":[125,212,291,312],"high-dynamic-range":[126],"logarithmic,":[127],"pipeline":[128],"analog-to-digital":[129],"converter":[130],"(ADC).":[131],"To":[132],"save":[133],"consumption,":[137],"dynamic-range":[140],"log":[141],"ADC":[142],"used,":[144],"making":[145],"analog":[146,170],"automatic":[147],"gain":[148],"unnecessary.":[150],"redundant":[152],"1.5b":[153],"architecture":[154],"relaxes":[155],"requirements":[157],"comparator":[160,163],"accuracy":[161],"reference":[164],"voltage":[165],"accuracy.":[166],"Instead":[167],"an":[169,172],"filter,":[171],"on-chip":[173,190,199],"digital":[174],"filter":[175],"separates":[176],"low":[178],"field":[181],"potential":[182],"signal":[183,263],"from":[184,280,303,310],"spike":[187],"energy.":[188],"An":[189],"controller":[191],"generates":[192],"patterns":[194],"64":[198,203,219],"current-steering":[200],"DACs.":[201,224],"DACs":[204],"formed":[206],"as":[207,274,276],"cascade":[209],"shared":[213],"2-bit":[214],"coarse":[215],"current":[216],"DAC":[217],"individual":[220],"bi-directional":[221],"4-bit":[222],"fine":[223],"coarse/fine":[226],"configuration":[227],"saves":[228],"die":[229],"since":[231],"MSB":[233],"devices":[234],"tend":[235],"be":[237],"large.":[238],"Real-time":[239],"was":[242],"recorded":[243,261,284],"connected":[248],"microprobes":[250],"that":[251],"were":[252],"chronically":[253],"implanted":[254],"two":[256],"Long":[257],"Evans":[258],"rats.":[259],"in-vivo":[262,335],"clearly":[264],"shows":[265],"spikes":[267],"10.2":[269],"dB":[270],"signal-to-noise":[271],"ratio":[272],"(SNR)":[273],"well":[275],"periodic":[278],"artifact":[279],"stimulation.":[282],"information":[286,309],"has":[287],"been":[288],"analyzed":[289],"unit":[292],"sorting":[293,320],"principal":[295],"component":[296],"analysis":[297,321],"(PCA).":[298],"PCA":[300,324],"scattering":[301],"plots":[302],"multi-layers":[304],"cortex":[306],"represent":[307],"diverse":[308],"either":[311],"or":[313],"multiple":[314],"sources.":[316],"single-unit":[318],"along":[322],"verifies":[325],"feasibility":[327],"implantable":[330],"CDBS":[331],"recording":[337],"interface":[338],"applications.":[339]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}