{"id":"https://openalex.org/W1013854822","doi":null,"title":"Development of validation of RP-HPLC method for determination of novel derivatives of daunorubicin","display_name":"Development of validation of RP-HPLC method for determination of novel derivatives of daunorubicin","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W1013854822","mag":"1013854822"},"language":"en","primary_location":{"id":"mag:1013854822","doi":null,"is_oa":false,"landing_page_url":"https://www.infona.pl/resource/bwmeta1.element.baztech-article-BPP2-0003-0007?locale=en","pdf_url":null,"source":{"id":"https://openalex.org/S138558885","display_name":"Chemia Analityczna","issn_l":"0009-2223","issn":["0009-2223"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319762","host_organization_name":"Polish Chemical Society","host_organization_lineage":["https://openalex.org/P4310319762"],"host_organization_lineage_names":["Polish Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chemia Analityczna","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107823846","display_name":"Ma\u0142gorzata \u0141ukawska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118668","display_name":"Instytut Biotechnologii i Antybiotyk\u00f3w","ror":"https://ror.org/024za3n32","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210093239","https://openalex.org/I4210118668"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Ma\u0142gorzata \u0141ukawska","raw_affiliation_strings":["Department of Modified Antibiotics, Institute of Biotechnology and Antibiotics, ul Staro\u015bci\u0144ska 5, 02-515 Warszawa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Modified Antibiotics, Institute of Biotechnology and Antibiotics, ul Staro\u015bci\u0144ska 5, 02-515 Warszawa","institution_ids":["https://openalex.org/I4210118668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037791964","display_name":"Irena Oszczapowicz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Irena Oszczapowicz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008890719","display_name":"Anna Jeli\u0144ska","orcid":"https://orcid.org/0000-0002-3019-5844","observed_orcids":["https://orcid.org/0000-0002-3019-5844"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Jeli\u0144ska","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3019-5844","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060145089","display_name":"Judyta Cielecka\u2010Piontek","orcid":"https://orcid.org/0000-0003-0891-5419","observed_orcids":["https://orcid.org/0000-0003-0891-5419"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Judyta Cielecka\u2010Piontek","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0891-5419","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085855620","display_name":"Magdalena Zajac","orcid":"https://orcid.org/0000-0001-5744-3230","observed_orcids":["https://orcid.org/0000-0001-5744-3230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Zaja\u00e7","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5744-3230","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Leszek Dobrowolski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Leszek Dobrowolski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040323869","display_name":"Gra\u017cyna Zi\u00f3\u0142kowska","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gra\u017cyna Zi\u00f3\u0142kowska","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053894018","display_name":"Przemys\u0142aw Zalewski","orcid":"https://orcid.org/0000-0002-5116-9426","observed_orcids":["https://orcid.org/0000-0002-5116-9426"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Przemys\u0142aw Zalewski","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5116-9426","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046518465","display_name":"Miko\u0142aj Piekarski","orcid":"https://orcid.org/0000-0002-9800-0708","observed_orcids":["https://orcid.org/0000-0002-9800-0708"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miko\u0142aj Piekarski","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9800-0708","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Anna Krause","orcid":"https://orcid.org/0000-0003-1924-9183","observed_orcids":["https://orcid.org/0000-0003-1924-9183"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Krause","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1924-9183","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5038308791","display_name":"Justyna Uszak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Uszak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2258,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.54545891,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"54","issue":"5","first_page":"907","last_page":"917"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/daunorubicin-derivatives","display_name":"daunorubicin derivatives","score":0.9909999966621399},{"id":"https://openalex.org/keywords/rp-hplc-method-validation","display_name":"RP-HPLC method validation","score":0.8859999775886536},{"id":"https://openalex.org/keywords/simultaneous-determination","display_name":"simultaneous determination","score":0.7699999809265137},{"id":"https://openalex.org/keywords/methodological-robustness","display_name":"method robustness","score":0.5540000200271606},{"id":"https://openalex.org/keywords/drug-quantification","display_name":"pharmaceutical analysis","score":0.3619999885559082}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9251493215560913},{"id":"https://openalex.org/C2781021840","wikidata":"https://www.wikidata.org/wiki/Q411659","display_name":"Daunorubicin","level":3,"score":0.8901892304420471},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.8482152223587036},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.8075900077819824},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.5688666105270386},{"id":"https://openalex.org/C2777463227","wikidata":"https://www.wikidata.org/wiki/Q408047","display_name":"Acetonitrile","level":2,"score":0.5447434186935425},{"id":"https://openalex.org/C2779607525","wikidata":"https://www.wikidata.org/wiki/Q14982","display_name":"Methanol","level":2,"score":0.5171862840652466},{"id":"https://openalex.org/C118792377","wikidata":"https://www.wikidata.org/wiki/Q108584245","display_name":"Selectivity","level":3,"score":0.43324556946754456},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08067288994789124},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1013854822","doi":null,"is_oa":false,"landing_page_url":"https://www.infona.pl/resource/bwmeta1.element.baztech-article-BPP2-0003-0007?locale=en","pdf_url":null,"source":{"id":"https://openalex.org/S138558885","display_name":"Chemia Analityczna","issn_l":"0009-2223","issn":["0009-2223"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319762","host_organization_name":"Polish Chemical Society","host_organization_lineage":["https://openalex.org/P4310319762"],"host_organization_lineage_names":["Polish Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chemia Analityczna","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2481183414"],"related_works":["https://openalex.org/W4402540574","https://openalex.org/W4206070844","https://openalex.org/W4229372146","https://openalex.org/W3120884011","https://openalex.org/W4409830809","https://openalex.org/W2390150496","https://openalex.org/W7219419358","https://openalex.org/W2733785238","https://openalex.org/W2052550241","https://openalex.org/W7135647857"],"abstract_inverted_index":{"An":[0,30],"isocratic":[1],"HPLC":[2],"method":[3,75],"with":[4,78],"UV":[5],"detection":[6],"for":[7,105],"simultaneous":[8],"determination":[9,17,108],"of":[10,14,18,61,85,88,99,109,111,119],"four":[11],"novel":[12],"derivatives":[13,20,110],"daunorubicin":[15,112],"and":[16,28,32,90,92,107,115],"selected":[19],"in":[21,113],"commonly":[22],"used":[23,104],"intravenous":[24],"solvents":[25],"was":[26,71,76],"developed":[27],"validated.":[29],"RP-column":[31],"an":[33],"acetonitrile-methanol-(2.88":[34],"g":[35],"L":[36,44],"-1":[37,45,65],"sodium":[39],"laurisulfate":[40],"+":[41],"1.6":[42],"mL":[43,63],"85%":[47],"H":[48],"3":[49],"PO":[50],"4":[51],"),":[52],"9:1:10":[53],"v/v/v":[54],"mobile":[55],"phase":[56],"at":[57],"a":[58],"flow":[59],"rate":[60],"1.5":[62],"min":[64],"were":[67],"used.":[68],"Detection":[69],"wavelength":[70],"254":[72],"nm.":[73],"The":[74],"validated":[77],"regard":[79],"to":[80],"selectivity,":[81],"linearity,":[82],"precision,":[83],"limit":[84,87],"detection,":[86],"quantitation,":[89],"robustness,":[91],"did":[93],"not":[94],"require":[95],"any":[96],"preliminary":[97],"treatment":[98],"samples.":[100],"It":[101],"can":[102],"be":[103],"identification":[106],"pharmaceuticals":[114],"during":[116],"kinetic":[117],"studies":[118],"these":[120],"derivatives.":[121]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}