{"id":"https://openalex.org/W100887304","doi":null,"title":"Lipodystrophy and dyslipidemia among patients taking first-line, World Health Organization-recommended highly active antiretroviral therapy regimens in Western India.","display_name":"Lipodystrophy and dyslipidemia among patients taking first-line, World Health Organization-recommended highly active antiretroviral therapy regimens in Western India.","publication_year":2005,"publication_date":"2005-06-01","ids":{"openalex":"https://openalex.org/W100887304","mag":"100887304","pmid":"https://pubmed.ncbi.nlm.nih.gov/15905737"},"language":"en","primary_location":{"id":"pmid:15905737","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15905737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of acquired immune deficiency syndromes (1999)","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035384275","display_name":"Sanjay N. Pujari","orcid":"https://orcid.org/0000-0002-4571-650X","observed_orcids":["https://orcid.org/0000-0002-4571-650X"]},"institutions":[{"id":"https://openalex.org/I2801897644","display_name":"Ruby Hall Clinic","ror":"https://ror.org/017bedv79","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2801897644"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sanjay N Pujari","raw_affiliation_strings":["Department of HIV Medicine, Ruby Hall Clinic, Pune, Maharashtra, India. san1@medscape.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of HIV Medicine, Ruby Hall Clinic, Pune, Maharashtra, India. san1@medscape.com","institution_ids":["https://openalex.org/I2801897644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036485618","display_name":"Ameet N. Dravid","orcid":"https://orcid.org/0000-0002-1909-7530","observed_orcids":["https://orcid.org/0000-0002-1909-7530"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ameet Dravid","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086113891","display_name":"Eknath Naik","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eknath Naik","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069564304","display_name":"Shobha Bhagat","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shobha Bhagat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067458683","display_name":"Kaley Tash","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kaley Tash","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054011082","display_name":"Jeffrey P. Nadler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey P Nadler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5061720004","display_name":"John T. Sinnott","orcid":"https://orcid.org/0000-0002-4062-6150","observed_orcids":["https://orcid.org/0000-0002-4062-6150"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John T Sinnott","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.1231,"has_fulltext":false,"cited_by_count":101,"citation_normalized_percentile":{"value":0.97532163,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"39","issue":"2","first_page":"199","last_page":"202"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipodystrophy","display_name":"lipodystrophy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9710000157356262},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.9879999756813049},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.9269999861717224},{"id":"https://openalex.org/keywords/highly-active-antiretroviral-therapy","display_name":"highly active antiretroviral therapy","score":0.9629999995231628},{"id":"https://openalex.org/keywords/zidovudine","display_name":"zidovudine","score":0.8399999737739563},{"id":"https://openalex.org/keywords/stavudine","display_name":"stavudine","score":0.8759999871253967},{"id":"https://openalex.org/keywords/nevirapine","display_name":"nevirapine","score":0.875},{"id":"https://openalex.org/keywords/lipoatrophy","display_name":"lipoatrophy","score":0.8930000066757202},{"id":"https://openalex.org/keywords/lipohypertrophy","display_name":"lipohypertrophy","score":0.9559999704360962},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.8130000233650208},{"id":"https://openalex.org/keywords/antiretroviral-therapy-adverse-effects","display_name":"antiretroviral therapy adverse effects","score":0.6830000281333923},{"id":"https://openalex.org/keywords/tenofovir","display_name":"tenofovir","score":0.7870000004768372},{"id":"https://openalex.org/keywords/abacavir","display_name":"abacavir","score":0.9610000252723694}],"concepts":[{"id":"https://openalex.org/C2780941825","wikidata":"https://www.wikidata.org/wiki/Q1538213","display_name":"Lipodystrophy","level":5,"score":0.9443157911300659},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.8482906222343445},{"id":"https://openalex.org/C2779889181","wikidata":"https://www.wikidata.org/wiki/Q423984","display_name":"Stavudine","level":5,"score":0.7657264471054077},{"id":"https://openalex.org/C2779546735","wikidata":"https://www.wikidata.org/wiki/Q3500973","display_name":"Lipoatrophy","level":5,"score":0.7194964289665222},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6938962936401367},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6046672463417053},{"id":"https://openalex.org/C2777869810","wikidata":"https://www.wikidata.org/wiki/Q422631","display_name":"Lamivudine","level":4,"score":0.6019809246063232},{"id":"https://openalex.org/C2780216070","wikidata":"https://www.wikidata.org/wiki/Q198504","display_name":"Zidovudine","level":4,"score":0.5553075671195984},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.42983344197273254},{"id":"https://openalex.org/C2779130552","wikidata":"https://www.wikidata.org/wiki/Q263713","display_name":"Nevirapine","level":5,"score":0.4140769839286804},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3540290594100952},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.21245133876800537},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.20568951964378357},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.18344685435295105},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.16171610355377197},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.11268740892410278},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.0727805495262146},{"id":"https://openalex.org/C2780593183","wikidata":"https://www.wikidata.org/wiki/Q6844","display_name":"Hepatitis B virus","level":3,"score":0.0},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003710","descriptor_name":"Demography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008060","descriptor_name":"Lipodystrophy","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D008060","descriptor_name":"Lipodystrophy","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014944","descriptor_name":"World Health Organization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023241","descriptor_name":"Antiretroviral Therapy, Highly Active","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:15905737","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15905737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of acquired immune deficiency syndromes (1999)","raw_type":"Journal Article"},{"id":"mag:100887304","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15905737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W168881706","https://openalex.org/W1984738039","https://openalex.org/W2015473003","https://openalex.org/W2022225339","https://openalex.org/W2025721425","https://openalex.org/W2026770987","https://openalex.org/W2033271256","https://openalex.org/W2056779298","https://openalex.org/W2081299887","https://openalex.org/W2084224138","https://openalex.org/W2105912359","https://openalex.org/W2106984740","https://openalex.org/W2142854127","https://openalex.org/W2156424907","https://openalex.org/W2159584933","https://openalex.org/W2323323105","https://openalex.org/W2324473093"],"related_works":["https://openalex.org/W2139602925","https://openalex.org/W19488281","https://openalex.org/W2128159831","https://openalex.org/W7057965870","https://openalex.org/W2322187157","https://openalex.org/W1223465430","https://openalex.org/W7100045492","https://openalex.org/W2021067597","https://openalex.org/W7096677525","https://openalex.org/W1996742702"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"determine":[2],"the":[3,133,145,170,188,197],"prevalence":[4,146,160,207],"of":[5,147,161,174,208],"lipodystrophy,":[6,209],"dyslipidemia,":[7,210],"and":[8,37,49,59,62,111,122,141,151,163,211,245],"hyperglycemia":[9,165,212],"among":[10],"HIV-infected":[11],"patients":[12,36,135,175,214],"taking":[13,215],"long-term,":[14],"first-line,":[15],"World":[16],"Health":[17],"Organization":[18],"(WHO)-recommended":[19],"generic":[20,218],"highly":[21],"active":[22],"antiretroviral":[23,233],"therapy":[24],"(HAART)":[25],"regimens":[26],"in":[27,169,187,213,220],"India.":[28,222],"DESIGN:":[29],":":[30],"Cross-sectional":[31],"study.":[32],"METHODS:":[33],"Asymptomatic,":[34],"antiretroviral-naive":[35],"those":[38],"treated":[39],"for":[40,55],">":[41,86,94,100,117,179],"1":[42],"year":[43],"with":[44,126,156,176],"zidovudine":[45],"(ZDV)/lamivudine":[46],"(3TC)/nevirapine":[47],"(NVP)":[48],"stavudine":[50],"(d4T)/3TC/NVP":[51],"were":[52,65,79,129],"subjectively":[53],"assessed":[54],"lipodystrophy":[56,148],"(lipoatrophy,":[57],"lipohypertrophy,":[58],"mixed":[60],"patterns),":[61],"lipid":[63],"profiles":[64],"determined":[66],"after":[67],"an":[68],"overnight":[69],"fast.":[70],"The":[71,159],"US":[72],"National":[73],"Cholesterol":[74],"Education":[75],"Program":[76],"III":[77],"guidelines":[78],"used":[80],"to":[81,224,229,239],"define":[82],"dyslipidemia":[83,162],"(total":[84],"cholesterol":[85,93,107,115],"or":[87,95,101,118,180],"=":[88,96,102,119,181],"200":[89],"mg/dL,":[90,98,104,110],"low-density":[91],"lipoprotein":[92,106,114,178,200],"130":[97],"triglycerides":[99],"150":[103,142],"high-density":[105,177],"<":[108],"40":[109],"total":[112,198],"cholesterol/high-density":[113,199],"ratio":[116],"6.5).":[120],"Prevalence":[121],"risk":[123],"factors":[124],"associated":[125,155],"these":[127,226],"complications":[128,227],"determined.":[130],"RESULTS:":[131],"Of":[132],"306":[134],"(126":[136],"controls,":[137],"30":[138],"on":[139,143,196],"ZDV/3TC/NVP,":[140],"d4T/3TC/NVP),":[144],"was":[149,153,166,184],"46.1%,":[150],"lipoatrophy":[152],"significantly":[154,167,185],"d4T":[157],"use.":[158],"fasting":[164],"higher":[168,186],"treatment":[171,189],"groups.":[172],"Proportion":[173],"60":[182],"mg/dL":[183],"groups;":[190],"however,":[191],"this":[192],"had":[193],"little":[194],"impact":[195],"ratio.":[201],"CONCLUSION:":[202],"There":[203],"is":[204],"a":[205],"high":[206],"long-term":[216],"WHO-recommended":[217],"HAART":[219],"western":[221],"Interventions":[223],"address":[225],"need":[228],"be":[230],"incorporated":[231],"into":[232],"scale-up":[234],"programs,":[235],"including":[236],"improving":[237],"access":[238],"alternative":[240],"less-offending":[241],"drugs":[242],"like":[243],"tenofovir":[244],"abacavir.":[246]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}