{"id":"https://openalex.org/W1002503553","doi":null,"title":"Prevalence of Helicobacter pylori vacuolating cytotoxin A gene as apredictive marker for different gastrodoudenal diseases.","display_name":"Prevalence of Helicobacter pylori vacuolating cytotoxin A gene as apredictive marker for different gastrodoudenal diseases.","publication_year":2011,"publication_date":"2011-04-30","ids":{"openalex":"https://openalex.org/W1002503553","mag":"1002503553"},"language":"en","primary_location":{"id":"mag:1002503553","doi":null,"is_oa":false,"landing_page_url":"http://sites.kowsarpub.com/archcid/articles/73296.html#abstract","pdf_url":null,"source":{"id":"https://openalex.org/S2765030017","display_name":"Archives of Clinical Infectious Diseases","issn_l":"2345-2641","issn":["2345-2641"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319135","host_organization_name":"Shahid Beheshti University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319135"],"host_organization_lineage_names":["Shahid Beheshti University of Medical Sciences"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Archives of Clinical Infectious Diseases","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027069971","display_name":"Mohammad Kargar","orcid":"https://orcid.org/0000-0002-9531-3645","observed_orcids":["https://orcid.org/0000-0002-9531-3645"]},"institutions":[{"id":"https://openalex.org/I4210108307","display_name":"Islamic Azad University, Jahrom Branch","ror":"https://ror.org/01v0kyj08","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210108307"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Kargar","raw_affiliation_strings":["Department of Microbiology,Jahrom Branch Islamic Azad University, Jahrom, IR Iran"],"raw_orcid":"https://orcid.org/0000-0002-9531-3645","affiliations":[{"raw_affiliation_string":"Department of Microbiology,Jahrom Branch Islamic Azad University, Jahrom, IR Iran","institution_ids":["https://openalex.org/I4210108307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078796858","display_name":"Negar Souod","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108307","display_name":"Islamic Azad University, Jahrom Branch","ror":"https://ror.org/01v0kyj08","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210108307"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Negar Souod","raw_affiliation_strings":["Department of Microbiology, Jahrom Branch, Young Researchers Club, Islamic Azad University, Jahrom, IR Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Jahrom Branch, Young Researchers Club, Islamic Azad University, Jahrom, IR Iran","institution_ids":["https://openalex.org/I4210108307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044205978","display_name":"Abbas Doosti","orcid":"https://orcid.org/0000-0001-8052-5963","observed_orcids":["https://orcid.org/0000-0001-8052-5963","https://orcid.org/0000-0002-4889-3325"]},"institutions":[{"id":"https://openalex.org/I4210121772","display_name":"Islamic Azad University of Shahrekord","ror":"https://ror.org/02tbw3b35","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210121772"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Abbas Doosti","raw_affiliation_strings":["Biotechnology Research Center, Shahrekord Branch, Islamic Azad University, Shahrekord, IR Iran"],"raw_orcid":"https://orcid.org/0000-0001-8052-5963","affiliations":[{"raw_affiliation_string":"Biotechnology Research Center, Shahrekord Branch, Islamic Azad University, Shahrekord, IR Iran","institution_ids":["https://openalex.org/I4210121772"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064789742","display_name":"Sadegh Ghorbani-Dalini","orcid":"https://orcid.org/0000-0002-7166-0626","observed_orcids":["https://orcid.org/0000-0002-7166-0626"]},"institutions":[{"id":"https://openalex.org/I4210108307","display_name":"Islamic Azad University, Jahrom Branch","ror":"https://ror.org/01v0kyj08","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210108307"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Sadegh Ghorbani-Dalini","raw_affiliation_strings":["Department of Microbiology, Jahrom Branch, Young Researchers Club, Islamic Azad University, Jahrom, IR Iran"],"raw_orcid":"https://orcid.org/0000-0002-7166-0626","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Jahrom Branch, Young Researchers Club, Islamic Azad University, Jahrom, IR Iran","institution_ids":["https://openalex.org/I4210108307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8847,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.76434407,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"6","issue":"2","first_page":"85","last_page":"89"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":1.0},{"id":"https://openalex.org/keywords/vaca-gene","display_name":"vacA gene","score":0.8299999833106995},{"id":"https://openalex.org/keywords/vaca","display_name":"VacA","score":0.9120000004768372},{"id":"https://openalex.org/keywords/signal-peptide","display_name":"signal peptide","score":0.46399998664855957},{"id":"https://openalex.org/keywords/middle-region","display_name":"middle region","score":0.871999979019165},{"id":"https://openalex.org/keywords/gastroduodenal-diseases","display_name":"gastroduodenal diseases","score":0.8299999833106995},{"id":"https://openalex.org/keywords/molecular-epidemiology","display_name":"molecular epidemiology","score":0.6930000185966492},{"id":"https://openalex.org/keywords/chaharmahal-and-bakhtiari-province","display_name":"Chaharmahal and Bakhtiari Province","score":0.8870000243186951},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.8443416357040405},{"id":"https://openalex.org/C2778204961","wikidata":"https://www.wikidata.org/wiki/Q83146136","display_name":"CagA","level":4,"score":0.8416491746902466},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6334899663925171},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5437984466552734},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5166866779327393},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.49800682067871094},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.4611113369464874},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45095741748809814},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3744649887084961},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3355277478694916},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.28385406732559204},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2551170587539673}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1002503553","doi":null,"is_oa":false,"landing_page_url":"http://sites.kowsarpub.com/archcid/articles/73296.html#abstract","pdf_url":null,"source":{"id":"https://openalex.org/S2765030017","display_name":"Archives of Clinical Infectious Diseases","issn_l":"2345-2641","issn":["2345-2641"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319135","host_organization_name":"Shahid Beheshti University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319135"],"host_organization_lineage_names":["Shahid Beheshti University of Medical Sciences"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Archives of Clinical Infectious Diseases","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W87788839","https://openalex.org/W121944072","https://openalex.org/W1534504108","https://openalex.org/W1961207309","https://openalex.org/W1970422961","https://openalex.org/W1986867084","https://openalex.org/W1995832947","https://openalex.org/W2027513071","https://openalex.org/W2034974566","https://openalex.org/W2043046615","https://openalex.org/W2089821534","https://openalex.org/W2098846084","https://openalex.org/W2112157935","https://openalex.org/W2126007035","https://openalex.org/W2129552793","https://openalex.org/W2132387819","https://openalex.org/W2144870232","https://openalex.org/W2155053766","https://openalex.org/W2166849177","https://openalex.org/W2170711502","https://openalex.org/W2188354253","https://openalex.org/W2331236046","https://openalex.org/W4322578573"],"related_works":["https://openalex.org/W2022154133","https://openalex.org/W4322578573","https://openalex.org/W4389797191","https://openalex.org/W2277564035","https://openalex.org/W2137698924","https://openalex.org/W2012909349","https://openalex.org/W2793371315","https://openalex.org/W4408230520","https://openalex.org/W1502833057","https://openalex.org/W2338641634"],"abstract_inverted_index":{"Objectives:":[0],"Helicobacter":[3,308],"pylori":[4,8,72,129],"(":[6,40,54],"H.":[7,71,128],")":[9,45,59],"has":[10],"several":[11],"virulence":[12],"factors":[13],"such":[14],"as":[15],"vacA":[17,27,36,75,155,178],"and":[19,46,81,85,96,139,144,214,231,252,268,312],"cagA":[21],"genes.":[23],"Mosaicism":[24],"in":[25,79,121,249,293],"alleles":[29,53],"with":[30,88,272],"two":[31,47],"distinct":[32,48],"families":[33,49],"of":[34,50,64,69,124,153,284,296],"signal":[38],"sequences":[39],"s1":[41],",":[42,56,183,186,189,192,195,198,201,204,207,210,261,264],"s2":[44],"middle":[51],"region":[52,251],"m1":[55],"m2":[58],"is":[60],"reported.":[61],"The":[62,173],"aim":[63],"this":[65,250],"study":[66,102],"was":[67,103,254],"determination":[68],"allelic":[77],"types":[78],"Chaharmahal":[80,311],"Bakhtiyari":[82],"province,":[83],"Iran":[84],"their":[86,164],"correlation":[87],"six":[89],"different":[90,280],"gastroduodenal":[91],"diseases.":[92,315],"Patients":[95],"Methods:":[97],"This":[99],"cross-sectional":[100],"descriptive":[101],"performed":[104],"on":[105],"200":[106],"antral":[107],"gastric":[108,167,274],"biopsy":[109],"specimens":[110],"that":[111],"were":[112,132,160,218,244],"obtained":[113],"from":[114,281],"patients":[115],"undergoing":[116],"upper":[117],"gastrointestinal":[118],"tract":[119],"endoscopy":[120],"Hajar":[122],"Hospital":[123],"Shahrekord.":[125],"Initially,":[126],"strains":[131,243,248],"identified":[133],"by":[134],"rapid":[135],"urease":[136],"test":[137],"(RUT)":[138],"ureC":[141],"primers,":[143],"thereafter,":[145],"we":[146],"used":[147,161],"seven":[148],"specific":[149],"primers":[150],"for":[151],"detection":[152],"genotypes.":[157],"Statistical":[158],"analyses":[159],"to":[162,166],"find":[163],"relationship":[165,257],"disorders.":[168,275],"Results:":[171],"frequency":[174],"of\u00a0":[175],"the":[176,245,277,285],"alleles,":[180],"s1a/m1a":[182,260],"s1a/m1b":[185],"s1a/m2":[188,241,263],"s1b/m1a":[191],"s1b/m1b":[194],"s1b/m2":[197],"s1c/m1a":[200,270],"s1c/m1b":[203],"s1c/m2":[206],"s2/m1a":[209],"s2/m1b":[212],"s2/m2":[216,266],"respectively,":[219],"27(16.46%),":[220],"8(4.87%),":[221],"45(28.43%),":[222],"7(4.26%),":[223],"5(3.04%),":[224],"10(6.09%),":[225],"12(7.31%),":[226],"4(2.43%),":[227],"18(10.97%),":[228],"6(3.65%),":[229],"0":[230],"22(13.41%).":[232],"Conclusion:":[238],"most":[246],"prevalent":[247],"there":[253],"a":[255],"considerable":[256],"between":[258],"some":[273],"As":[276],"findings":[278],"are":[279,291],"other":[282,294],"regions":[283],"world,":[286],"extended":[287],"molecular":[288],"epidemiologic":[289],"investigations":[290],"recommended":[292],"cities":[295],"Iran.":[297],"Keywords":[303],":":[306],"pylori,":[309],"vacA,":[310],"Bakhtiari,":[313],"Gastroduodenal":[314]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}