{"id":"https://openalex.org/W100057741","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.669.1","title":"Exploratory Microarray Analysis Provides Genetic Insights into Nutrition and Nutrition Plus Strength Training Interventions in Latino Adolescents","display_name":"Exploratory Microarray Analysis Provides Genetic Insights into Nutrition and Nutrition Plus Strength Training Interventions in Latino Adolescents","publication_year":2010,"publication_date":"2010-04-01","ids":{"openalex":"https://openalex.org/W100057741","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.669.1","mag":"100057741"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.24.1_supplement.669.1","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.669.1","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.24.1_supplement.669.1","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033019632","display_name":"Michael C. Gao","orcid":"https://orcid.org/0000-0003-0534-4403","observed_orcids":["https://orcid.org/0000-0003-0534-4403"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael C Gao","raw_affiliation_strings":["Physiological Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiological Science","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006092878","display_name":"Daniel M. Croymans","orcid":"https://orcid.org/0000-0001-9805-8048","observed_orcids":["https://orcid.org/0000-0001-9805-8048"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel M Croymans","raw_affiliation_strings":["Physiological Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiological Science","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081109402","display_name":"Hooman Allayee","orcid":"https://orcid.org/0000-0002-2384-5239","observed_orcids":["https://orcid.org/0000-0002-2384-5239"]},"institutions":[{"id":"https://openalex.org/I4210095633","display_name":"General Department of Preventive Medicine","ror":"https://ror.org/00ntrnw83","country_code":"VN","type":"government","lineage":["https://openalex.org/I4210095633"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Hooman Allayee","raw_affiliation_strings":["Preventive Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Preventive Medicine","institution_ids":["https://openalex.org/I4210095633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014339990","display_name":"Michael I. Goran","orcid":"https://orcid.org/0000-0002-6897-6961","observed_orcids":["https://orcid.org/0000-0002-6897-6961"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210095633","display_name":"General Department of Preventive Medicine","ror":"https://ror.org/00ntrnw83","country_code":"VN","type":"government","lineage":["https://openalex.org/I4210095633"]}],"countries":["US","VN"],"is_corresponding":false,"raw_author_name":"Michael I Goran","raw_affiliation_strings":["Physiology and Biophysics, Keck School of Medicine University of Southern California, Los Angeles, CA","Preventive Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiology and Biophysics, Keck School of Medicine University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Preventive Medicine","institution_ids":["https://openalex.org/I4210095633"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110120255","display_name":"Christian K. Roberts","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christian K Roberts","raw_affiliation_strings":["Epidemiology and Center for Metabolic Disease Prevention, University of California Los Angeles, Los Angeles, CA","Physiological Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Center for Metabolic Disease Prevention, University of California Los Angeles, Los Angeles, CA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Physiological Science","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00989252,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"24","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13354","display_name":"Genetics and Physical Performance","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nutrition-education","display_name":"nutrition education","score":0.6759999990463257},{"id":"https://openalex.org/keywords/resistance-training","display_name":"resistance training","score":0.8679999709129333},{"id":"https://openalex.org/keywords/latino-adolescents","display_name":"Latino adolescents","score":0.9750000238418579},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.8700000047683716},{"id":"https://openalex.org/keywords/leukocytes","display_name":"leukocytes","score":0.7749999761581421},{"id":"https://openalex.org/keywords/type-2-diabetes-prevention","display_name":"type 2 diabetes prevention","score":0.7829999923706055},{"id":"https://openalex.org/keywords/metabolic-adaptation","display_name":"metabolic adaptation","score":0.6259999871253967},{"id":"https://openalex.org/keywords/carbohydrate-metabolism","display_name":"carbohydrate metabolism","score":0.9240000247955322},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":1.0},{"id":"https://openalex.org/keywords/functional-gene-networks","display_name":"functional gene networks","score":0.5690000057220459},{"id":"https://openalex.org/keywords/dietary-fiber","display_name":"dietary fiber","score":0.5270000100135803},{"id":"https://openalex.org/keywords/low-sugar-diet","display_name":"low-sugar diet","score":0.7429999709129333},{"id":"https://openalex.org/keywords/exercise-intervention","display_name":"exercise intervention","score":0.4519999921321869}],"concepts":[{"id":"https://openalex.org/C2779018089","wikidata":"https://www.wikidata.org/wiki/Q17014303","display_name":"Fold change","level":4,"score":0.5148465037345886},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.48712706565856934},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.483296662569046},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4675760567188263},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4583302438259125},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.42472606897354126},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4128449857234955},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4054073691368103},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34379255771636963},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30978846549987793}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.24.1_supplement.669.1","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.669.1","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.24.1_supplement.669.1","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.4359000027179718}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2022339586","https://openalex.org/W7097273600","https://openalex.org/W2006221725","https://openalex.org/W2001544031","https://openalex.org/W2109148864","https://openalex.org/W2341043834","https://openalex.org/W2060314544","https://openalex.org/W7099147672","https://openalex.org/W2158884591","https://openalex.org/W4415094305"],"abstract_inverted_index":{"Diet":[0],"and":[1,51,64,92,103,123,142,146,150,168,180,182],"exercise":[2],"are":[3,24],"critical":[4],"for":[5,166,170],"preventing":[6],"metabolic":[7,22],"diseases":[8],"such":[9],"as":[10],"type":[11,190],"2":[12,41],"diabetes,":[13],"but":[14],"the":[15,53,130,156,189],"underlying":[16],"gene":[17],"expression":[18],"changes":[19,177],"associated":[20],"with":[21],"adaptations":[23],"unclear.":[25],"We":[26,59,74],"previously":[27],"implemented":[28],"a":[29],"16\u2010week":[30],"high\u2010fiber":[31],"low\u2010sugar":[32],"nutrition":[33],"education":[34],"program":[35],"(N,":[36],"n=16)":[37],"or":[38,82],"that":[39],"plus":[40],"d/wk":[42],"of":[43,129,155,191,195],"strength":[44],"training":[45],"(N+ST,":[46],"n=12)":[47],"in":[48,70,80,89,106],"Latino":[49],"adolescents,":[50],"explored":[52],"intervention":[54],"effects":[55],"on":[56],"transcriptional":[57],"profiles.":[58],"measured":[60],"mRNA":[61,175],"levels":[62],"pre\u2010":[63],"post\u2010intervention":[65],"using":[66],"Illumina's":[67],"Expression":[68],"BeadChip":[69],"white":[71],"blood":[72],"cells.":[73],"selected":[75],"genes":[76,197],"which":[77],"were":[78,127,153],"changed":[79,116],"N":[81,179],"N+ST":[83,136,181],"(p<0.05,":[84],"fold":[85],"change":[86],">1.41,":[87],"unchanged":[88],"control":[90],"group)":[91],"then":[93],"used":[94],"Ingenuity":[95],"Pathway":[96],"Analysis":[97],"to":[98,188],"determine":[99],"functional":[100,117,184],"networks":[101],"(p<0.001)":[102],"their":[104,183],"representation":[105],"established":[107],"canonical":[108,164],"pathways":[109,133,165],"(p<0.01).":[110],"For":[111,135],"N,":[112,167],"we":[113,137,161],"found":[114,138,162],"14":[115],"networks.":[118],"Carbohydrate":[119],"metabolism,":[120,122],"lipid":[121],"small":[124],"molecule":[125],"biochemistry":[126],"3":[128],"top":[131,157],"5":[132,169],"noted.":[134],"33;":[139],"cell\u2010to\u2010cell":[140],"signaling":[141],"interaction,":[143],"cell":[144,151],"growth":[145],"proliferation,":[147],"cellular":[148],"movement,":[149],"development":[152],"4":[154],"5.":[158],"In":[159],"addition,":[160],"8":[163],"N+ST.":[171],"Results":[172],"show":[173],"relevant":[174],"level":[176],"after":[178],"groupings":[185],"broadly":[186],"relate":[187],"intervention.":[192],"Further":[193],"investigation":[194],"these":[196],"may":[198],"provide":[199],"valuable":[200],"insights":[201],"into":[202],"therapeutic":[203],"mechanisms.":[204]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}