{"id":"https://openalex.org/T13313","display_name":"Dupuytren's Contracture and Treatments","description":"This cluster of papers focuses on the treatment, pathogenesis, and epidemiology of Dupuytren's disease, including the use of Collagenase Clostridium Histolyticum, fasciectomy, needle fasciotomy, and radiotherapy. It also explores genetic susceptibility, Wnt signaling, myofibroblasts, TGF-\u00df1 stimulation, and contracture recurrence.","keywords":[{"id":"https://openalex.org/keywords/dupuytren-s-contracture","display_name":"Dupuytren's contracture","score":0.8193},{"id":"https://openalex.org/keywords/peyronie-s-disease","display_name":"Peyronie's disease","score":0.2144},{"id":"https://openalex.org/keywords/collagenase-clostridium-histolyticum","display_name":"collagenase clostridium histolyticum","score":0.5354},{"id":"https://openalex.org/keywords/palmar-fascia","display_name":"palmar fascia","score":0.8726},{"id":"https://openalex.org/keywords/fasciectomy","display_name":"fasciectomy","score":0.7453},{"id":"https://openalex.org/keywords/hand-contracture","display_name":"hand contracture","score":0.5246},{"id":"https://openalex.org/keywords/collagenase-injection","display_name":"collagenase injection","score":0.6121},{"id":"https://openalex.org/keywords/palmar-aponeurosis","display_name":"palmar aponeurosis","score":0.5355},{"id":"https://openalex.org/keywords/percutaneous-needle-fasciotomy","display_name":"percutaneous needle fasciotomy","score":0.906},{"id":"https://openalex.org/keywords/finger-contracture","display_name":"finger contracture","score":0.3177},{"id":"https://openalex.org/keywords/limited-fasciectomy","display_name":"limited fasciectomy","score":0.9735},{"id":"https://openalex.org/keywords/plantar-fibromatosis","display_name":"plantar fibromatosis","score":0.3477},{"id":"https://openalex.org/keywords/fibroproliferative-disease","display_name":"fibroproliferative disorders","score":0.2671},{"id":"https://openalex.org/keywords/collagenase-clostridium-histolyticum-injection","display_name":"collagenase clostridium histolyticum injection","score":0.8206},{"id":"https://openalex.org/keywords/ledderhose-disease","display_name":"Ledderhose disease","score":0.5404},{"id":"https://openalex.org/keywords/needle-aponeurotomy","display_name":"needle aponeurotomy","score":0.8843},{"id":"https://openalex.org/keywords/needle-fasciotomy","display_name":"needle fasciotomy","score":0.8994},{"id":"https://openalex.org/keywords/dermofasciectomy","display_name":"dermofasciectomy","score":0.9172},{"id":"https://openalex.org/keywords/dupuytren-s-nodules","display_name":"Dupuytren's nodules","score":0.9504},{"id":"https://openalex.org/keywords/penile-plaque","display_name":"penile plaque","score":0.2846},{"id":"https://openalex.org/keywords/proximal-interphalangeal-joint-contracture","display_name":"proximal interphalangeal joint contracture","score":0.6582},{"id":"https://openalex.org/keywords/tunica-albuginea-fibrosis","display_name":"tunica albuginea fibrosis","score":0.4049},{"id":"https://openalex.org/keywords/partial-fasciectomy","display_name":"partial fasciectomy","score":0.9319},{"id":"https://openalex.org/keywords/dupuytren-s-cords","display_name":"Dupuytren's cords","score":0.9994},{"id":"https://openalex.org/keywords/metacarpophalangeal-joint-contracture","display_name":"metacarpophalangeal joint contracture","score":0.7692}],"legacy_keywords":"Collagenase Clostridium Histolyticum; Fasciectomy; Needle Fasciotomy; Wnt Signaling; Epidemiology; Genetic Susceptibility; Radiotherapy; Myofibroblasts; TGF-\u00df1 Stimulation; Contracture Recurrence","ids":{"openalex":"https://openalex.org/T13313","wikipedia":"https://en.wikipedia.org/wiki/Dupuytren%27s_contracture"},"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms"},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies"},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research"},{"id":"https://openalex.org/T10418","display_name":"Pelvic floor disorders treatments"},{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research"},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments"},{"id":"https://openalex.org/T11092","display_name":"Spondyloarthritis Studies and Treatments"},{"id":"https://openalex.org/T11576","display_name":"IgG4-Related and Inflammatory Diseases"},{"id":"https://openalex.org/T11991","display_name":"Soft tissue tumor case studies"},{"id":"https://openalex.org/T12110","display_name":"Bone and Dental Protein Studies"},{"id":"https://openalex.org/T12438","display_name":"Urticaria and Related Conditions"},{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes"},{"id":"https://openalex.org/T12604","display_name":"Glycogen Storage Diseases and Myoclonus"},{"id":"https://openalex.org/T12747","display_name":"Moyamoya disease diagnosis and treatment"},{"id":"https://openalex.org/T12800","display_name":"Musculoskeletal synovial abnormalities and treatments"},{"id":"https://openalex.org/T12866","display_name":"Urologic and reproductive health conditions"},{"id":"https://openalex.org/T12960","display_name":"Heterotopic Ossification and Related Conditions"},{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research"},{"id":"https://openalex.org/T13452","display_name":"GDF15 and Related Biomarkers"},{"id":"https://openalex.org/T13543","display_name":"Oropharyngeal Anatomy and Pathologies"},{"id":"https://openalex.org/T13962","display_name":"Omental and Epiploic Conditions"},{"id":"https://openalex.org/T14015","display_name":"Otitis Media and Relapsing Polychondritis"},{"id":"https://openalex.org/T14057","display_name":"Hypertrophic osteoarthropathy and related conditions"}],"works_count":8119,"cited_by_count":79871,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T13313","updated_date":"2026-10-21T03:01:35","created_date":"2024-01-23T15:27:17"}